Andrea Olea’s research while affiliated with Universidad del Desarrollo and other places

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Publications (4)


Arsenic Exposure During Pregnancy and Childhood: Factors Explaining Changes over a Decade
  • Article
  • Full-text available

March 2025

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24 Reads

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Mauricio Apablaza

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Arsenic chronic exposure, particularly in its inorganic form, represents a significant public health concern. This study was conducted in Arica, the northernmost city in the country, whose inhabitants have been exposed to inorganic arsenic both naturally through drinking water and anthropogenically due to a toxic waste disposal site. We explored changes in inorganic arsenic levels in a cohort of pregnant women and their children over a decade, identifying exposure trends and their determinants. We used data on arsenic exposure through maternal urine samples during pregnancy, collected by the Health Authority between 2013 and 2016 (measurement 1), and followed up with assessments of their children in 2023 (measurement 2). Temporal changes in inorganic arsenic concentration were analyzed using the Wilcoxon Signed-Rank test, and a mixed linear regression model was employed to determine which factors contributed to urinary inorganic arsenic levels. We did not observe significant differences in mean arsenic concentrations between the two-time points (p = 0.4026). The mixed linear regression model revealed that children consuming bottled water had 8.3% lower urinary inorganic arsenic concentrations than those drinking tap water (95% CI: −15.36 to −0.54%). Additionally, children from ethnic groups had 8.64% higher inorganic arsenic concentrations (95% CI: 0.49 to 17.5%), while those with caregivers with higher education showed a 13.67% reduction (95% CI: −25.06 to −0.56%). Despite mitigation efforts, these findings underscore the ongoing risk of inorganic arsenic exposure among vulnerable populations. They further emphasize the importance of addressing natural arsenic contamination in water and implementing targeted interventions to reduce disparities associated with socioeconomic and demographic factors.

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FIGURE 1 | Flowchart of study selection according to scoping review process (Worldwide, 2022).
FIGURE 2 | Summary of characteristics of included documents according to Population, Context, Concept (PCC) model (Worldwide, 2022).
FIGURE 4 | Proportion of documents by health objective and hardware (Worldwide, 2022).
Navigating Through Innovation in Elderly’s Health: A Scoping Review of Digital Health Interventions

Public Health Reviews

Objectives Comprehensively map and summarize digital health initiatives for the elderly and caregivers. Methods Scoping review between April and May 2022 based on Joanna Briggs methodology. Databases used included PubMed, Cochrane Library, CINAHL Plus, and Web of Science, along with grey literature and hand searches. Two reviewers independently conducted screening and eligibility phases, with a third resolving disagreements. Data were thematically analyzed. Results The review included 421 documents. Most documents were published between 2013 and 2022, with a recent increase. Most studies, originating from high-income countries, focused on home applications and were mainly in the testing and validation stages. Telephones and computers were the predominant devices. Health objectives included monitoring, prevention, and treatment, with interventions utilizing directed communication and personal health monitoring for individuals, and telemedicine and decision support for healthcare providers. Conclusion Increasing integration of technology in older adults’ lives, along with their increasing proficiency, is driving a significant rise in digital health interventions. Despite this growth, further research in middle- and low-income countries, for caregivers and evaluating effectiveness and feasibility of these technological interventions is needed.



IS DIGITAL HEALTH ENOUGH FOR THE ELDERLY AND CAREGIVERS IN CHILE, 2022?

September 2023

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8 Reads

The elderly's relationship with technology is limited, except for those who used digital devices for work. Technology is seen as a facilitator for daily tasks, including healthcare. Concerns mainly revolve around fraud, scams, misuse of personal information, and fear of device damage, widening the digital gap. O B J E C T I V E To understand experiences, interactions, and expectations that elderly, relatives and caregivers have regarding digital health.