Andrea Cossarizza’s research while affiliated with University of Modena and Reggio Emilia and other places

... 16 Another study analyzed a statue from Hellenistic art period, between 300 and 30 BC, of showing gynecomastia, marked by male breast tissue hypertrophy due to age-related endocrine changes. 17 However, gynecomastia can have a psychological impact to men due to the perception of a normal male body shape. ...

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A Dermatological Intervention of Gynecomastia in Young Asian Man with a History of Soy Product Consumption: A Case Report

... A range of international projects, including GWAS and whole exome studies [6,7], were conducted to assess between-subject variability in susceptibility to the virus. These studies uncovered a potential association between different polymorphisms (SNPs) and genetic predisposition to develop critical disease [8][9][10]. ...

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Use of artificial intelligence to assess genetic predisposition to develop critical COVID-19 disease: a comparative study of machine learning models

... Mitigation of the immune response to SARS-CoV-2 infection is also the primary rationale for dexamethasone treatment, which was found to positively impact survival in patients with severe COVID-19 6 . Studies in large European cohorts of patients with COVID-19 have identified several risk factors for viral susceptibility and survival, but have not shown any association with the IFNL4 locus 14,30,31 . This difference between the present study and previous large genome wide association studies can be explained by distinct endpoints. ...

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The common genetic variant rs1278960 determining expression of Interferon-lambda predicts inflammatory response in critically ill COVID-19 patients

... MeV is a morbillivirus of the family Paramyxoviridae that is transmitted through the respiratory tract, where alveolar macrophages and dendritic cells are the initial cellular targets of infection (18,19). These infected immune cells then traffic to the draining lymph nodes, where the virus replicates rapidly in lymphocytes that express the entry factor CD150/SLAMF1 (20)(21)(22)(23), followed by egress through lung epithelium that is mediated by basolateral expression of the Nectin-4 receptor (23)(24)(25)(26)(27). MeV is also known for causing immune amnesia through the depletion of CD150 + B and T cells in both primary and secondary lymphoid organs, increasing the morbidity and mortality rates from secondary infections with common childhood pathogens (28)(29)(30)(31)(32)(33)(34)(35). Immunological amnesia following MeV infection has been shown to markedly reduce the antibody repertoire toward common childhood pathogens, such as the human parainfluenza viruses, respiratory syncytial virus, coronaviruses, and cytomegalovirus (36). ...

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Immunological landscape of human lymphoid explants during measles virus infection

... One notable example of endorsement of vaccine hesitancy can be attributed to the poet and politician and leading exponent of Romanticism, Lord Byron (1788-1824), was openly sceptical of the smallpox immunisation method developed by Jenner in 1749. He went so far as to compare it to questionable medical practices and quackery prevalent at the time [38]. Although tetanus is now uncommon in resource-rich settings, the disease remains a threat to all unvaccinated people, particularly in resource-limited countries where the continued existence of C. tetani in the environment indicates that while the disease can be controlled, it cannot be eradicated. ...

Reference:

Tetanus: historical and palaeopathological aspects considering its current health impact

... The Russian review reported how the speed with which the COVID-19 Sputnik vaccine was developed and approved raised concerns about its safety and efficacy (Bucci et al. 2020). Russia became the first country in the world to approve a COVID-19 vaccine for widespread public use in August 2020, but the vaccine's efficacy and safety were allegedly announced before the clinical trials had been completed or data published . ...

Reference:

The PREPARED Code: A Global Code of Conduct for Research During Pandemics