Andrea Cossarizza’s research while affiliated with University of Modena and Reggio Emilia and other places

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Publications (14)


Response to Pfründer about the Kaspar Hauser case
  • Article

August 2024

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13 Reads

Clinics in Dermatology

Michael E. Habicht

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[...]

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Francesco Maria Galassi

Author Correction: Africa-specific human genetic variation near CHD1L associates with HIV-1 load
  • Article
  • Publisher preview available

September 2023

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84 Reads

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1 Citation

Nature

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Media release: Kaspar Hauser had been vaccinated. A detailed medical observation debunks the legend of captivity without any contact with humans (2023)

June 2023

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99 Reads

Media information: Press Kit English


Kaspar Hauser, the Child of Europe: are smallpox vaccination scars the clue to a two-century-old mystery?

June 2023

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29 Reads

We have explored the 19 th-century mystery of the identity of Kaspar Hauser, the so-called Child of Europe, from the perspective of the smallpox vaccination. We have highlighted the improbability that he was secretly inoculated based on the vaccination policies and methodologies applied at the time. This consideration allows for a reflection on the whole case and the importance of vaccination scars in ascertaining immunization against one of humanity's deadliest killers, especially given the recent monkeypox outbreak. https://www.sciencedirect.com/science/article/abs/pii/S0738081X23000500


Kaspar Hauser, the Child of Europe: Are smallpox vaccination scars the clue to a 2-century-old mystery?

June 2023

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12 Reads

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6 Citations

Clinics in Dermatology

We have explored the 19th-century mystery of the identity of Kaspar Hauser, the so-called Child of Europe, from the perspective of the smallpox vaccination. We have highlighted the improbability that he was secretly inoculated based on the vaccination policies and methodologies applied at the time. This consideration allows for a reflection on the whole case and the importance of vaccination scars in ascertaining immunization against one of humanity's deadliest killers, especially given the recent monkeypox outbreak.


Superior Vena Cava Syndrome and Gynecomastia in Antiquity: Paleodermatologic Considerations on Ageing in the Past

May 2023

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12 Reads

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4 Citations

Clinics in Dermatology

We explore the antiquity of two well-known conditions, often associated with advancing age, namely the superior vena cava syndrome and gynecomastia, through the veristic sculptural representation dating back to the Classical Age. The statue of the Old Fisherman from the "Paolo Orsi" Regional Archaeological Museum of Syracuse, Italy thanks to the extremely accurate rendering of the appearance of the cutaneous tissues, makes it possible to open a window on the antiquity and morphologic presentation of pathologic phenomena that would be difficult to infer solely from the human skeleton remains. The analysis of this statue also offers an opportunity to highlight the capacity of Hellenistic art in portraying human misery and illness.





Citations (6)


... 16 Another study analyzed a statue from Hellenistic art period, between 300 and 30 BC, of showing gynecomastia, marked by male breast tissue hypertrophy due to age-related endocrine changes. 17 However, gynecomastia can have a psychological impact to men due to the perception of a normal male body shape. ...

Reference:

A Dermatological Intervention of Gynecomastia in Young Asian Man with a History of Soy Product Consumption: A Case Report
Superior Vena Cava Syndrome and Gynecomastia in Antiquity: Paleodermatologic Considerations on Ageing in the Past
  • Citing Article
  • May 2023

Clinics in Dermatology

... La crisis sanitaria global fomentó la colaboración científica global, generando rápidamente datos clave del SARS-CoV-2, incluyendo genomas de referencia [5] y factores genéticos de susceptibilidad. Diversos proyectos internacionales, como estudios GWAS y de exoma completo [6,7] han investigado la variabilidad interpersonal frente al virus, y se han determinado una serie de polimorfismos (SNPs) que se asociarían una susceptibilidad genética a una mayor gravedad [8][9][10]. ...

A first update on mapping the human genetic architecture of COVID-19

Nature

... La crisis sanitaria global fomentó la colaboración científica global, generando rápidamente datos clave del SARS-CoV-2, incluyendo genomas de referencia [5] y factores genéticos de susceptibilidad. Diversos proyectos internacionales, como estudios GWAS y de exoma completo [6,7] han investigado la variabilidad interpersonal frente al virus, y se han determinado una serie de polimorfismos (SNPs) que se asociarían una susceptibilidad genética a una mayor gravedad [8][9][10]. ...

Mapping the human genetic architecture of COVID-19

Nature

... MeV is a morbillivirus of the family Paramyxoviridae that is transmitted through the respiratory tract, where alveolar macrophages and dendritic cells are the initial cellular targets of infection (18,19). These infected immune cells then traffic to the draining lymph nodes, where the virus replicates rapidly in lymphocytes that express the entry factor CD150/SLAMF1 (20)(21)(22)(23), followed by egress through lung epithelium that is mediated by basolateral expression of the Nectin-4 receptor (23)(24)(25)(26)(27). MeV is also known for causing immune amnesia through the depletion of CD150 + B and T cells in both primary and secondary lymphoid organs, increasing the morbidity and mortality rates from secondary infections with common childhood pathogens (28)(29)(30)(31)(32)(33)(34)(35). Immunological amnesia following MeV infection has been shown to markedly reduce the antibody repertoire toward common childhood pathogens, such as the human parainfluenza viruses, respiratory syncytial virus, coronaviruses, and cytomegalovirus (36). ...

Measles-induced immune amnesia likely recorded in the 18th century
  • Citing Article
  • July 2021

Journal of Clinical Virology

... One notable example of endorsement of vaccine hesitancy can be attributed to the poet and politician and leading exponent of Romanticism, Lord Byron (1788-1824), was openly sceptical of the smallpox immunisation method developed by Jenner in 1749. He went so far as to compare it to questionable medical practices and quackery prevalent at the time [38]. Although tetanus is now uncommon in resource-rich settings, the disease remains a threat to all unvaccinated people, particularly in resource-limited countries where the continued existence of C. tetani in the environment indicates that while the disease can be controlled, it cannot be eradicated. ...

Lord Byron (1788-1824) as the precursor of celebrities endorsing vaccine hesitancy: a cultural anthropological lesson for COVID-19 immunisation strategies
  • Citing Article
  • January 2021

Anthropologie

... In a 1999 editorial, the editor-in-chief of BMJ famously described peer review as "slow [authors' note--that is an especially problematic issue for early career researchers when it comes to grant applications or meeting the requirements for a graduate degree], expensive, highly subjective, prone to bias, easily abused, and poor at detecting gross defects." Recent highprofile cases that involved fraud and associated retractions (Clark et al. 2016;Byrne 2019;Bucci et al. 2020;Ledford andVan Noorden 2020, Viglione 2020;Pennisi 2021), the presence of paper mills (Else and Van Noorden 2021;Sabel et al. 2023;United2Act 2024), spoof articles in predatory journals (Bohannon 2013;Grudniewicz et al. 2019), editorial or procedural incompetence and bias (Weller 2001;Wang et al. 2016;Horbach and Halffman 2019), and the replication crisis (Open Science Collaboration 2015; Baker 2016a; Guttinger and Love 2019) have negatively impacted trust in a process that is foundational to science (Rowland 2002). It is important to note that the erosion of trust is mainly in the general public; researchers continue to show a strong level of trust in peer review as a process to improve the quality of science and scientific publications (Kratz and Strasser 2015; Elsevier and Sense about Science 2019). ...

Safety and efficacy of the Russian COVID-19 vaccine: more information needed

The Lancet