Am Sharifa's scientific contributions

Publications (13)

Article
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Rheumatoid arthritis (RA) is an autoimmune disorder that mainly affects joints.The cause of RA is believed to be a combination of genetic and environmental factors. Family history of RA increases the risk around three to five times. Smoking,Caucasian populations, increasing risk of RA.Periodontal disease has been associated with RA.Disease progress...
Article
Multidrug-resistant(MDR)bacteria was discovered as early as 1950s.Transmissible R factors of Enterobacteriaceae received greatest attention, the existence of plasmids were identified which confer antibiotic resistance in many genera. Plasmids also confer resistance to penicillin, chloramphenicol, erythromycin, and number of heavy metals. Multidrug-...
Article
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Thyroid cancer (TC) affects more women than men and those of Asian descent. Environmentalexposure to ionizing radiation from natural and artificial sources plays a significant role. Genetic causes include endocrine neoplasia type 2, particularly of the rare medullary form of the disease. Initial symptom is enlarged nodule, pain, changes in voice du...
Article
Full-text available
Thyroid cancer (TC) affects more women than men and those of Asian descent. Environmentalexposure to ionizing radiation from natural and artificial sources plays a significant role. Genetic causes include endocrine neoplasia type 2, particularly of the rare medullary form of the disease. Initial symptom is enlarged nodule, pain, changes in voice du...
Article
Full-text available
Gastric cancer (GC) is the most common cancer with high mortality worldwide. Highrate of GC deaths reported in China, Japan, and Korea. There are 56% new cases from Eastern Asia,41% from China, and11% from Japan. The common causes of GC include Helicobacter pylori infection which accounts for 60% of cases, pickled vegetables, smoking, alcohol intak...
Article
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In 2016,World Health Organization (WHO) declared a Public Health Emergency due to the recent outbreak of Zika fever in Brazil.Zika virus is a mosquito-borne flavivirus related to dengue virus. Infection can also spread by sexual transmission from infected men. Cases of vertical perinatal transmission have been reported, with multiple problems, incl...
Article
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Parkinson's disease (PD) is a metacentric neurodegenerative disorder results with accumulation and aggregation of alpha-synculein (α-Syn) (or alpha-synculeinopathy) in the substantia nigra in the central nervous system (CNS). Contributory factors include pesticide exposure, head injury and agriculture background. PD has been considered to be a non-...
Article
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Necrotizing fasciitis (NF) is a severe disease of sudden onset that spreads rapidly. The disease is more common in the adults and is rare in the children. The infection enters the body through a break in the skin such as cut or burn. Majority of the cases involve methicillin resistant Staphylococcus aureus(MRSA), anaerobic species, Enterobacteriace...
Article
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Thalassemia's are genetic disorders inherited from a person's parents. Thalassemia's are prevalent worldwide with 25,000 deaths in 2013.Highest rates are in the Mediterranean, Italy, Greece, Turkey, West Asia, North Africa, South Asian, and Southeast Asia. Highest carriers(30% of the population) in the Maldives.Thalassemia's are classified into alp...
Article
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Hemophilia a genetic disorder with patient's inability to stop bleeding. There are two main types of hemophilia, hemophiliaA due to not enough clotting factor VIII and hemophilia B due to not enough factor IX,and acquired hemophilia A(AHA) caused by autoantibodies against clotting factor VIII(FVIII).AHA is associated with malignancy,autoimmune diso...
Article
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Breast cancer is the common invasive cancer with high mortality worldwide. High incidence of breast cancer in South and central America,Southren ,Northren, Westren Europe, Ocenia and North America. Lowest breast cancer incidence in Africa and Asia.Risk factors includes: female sex old age, lifestyle, oral contraceptive, hormone replacement therapy,...
Article
Full-text available
Diphtheria outbreaks, though very rare, still occur worldwide, in the developed and developing countries. Diphtheria has high mortality in non-vaccinated populations. Corynebacterium diphtheria produce very potent toxin when infected with a bacteriophage that migrates the toxin-encoding genetic elements into bacteria. The R domain binds to a cell s...
Article
Rabies a zoonotic disease prevalent worldwide, with high mortality, more than a third of global toll in India. Dogs are the common animals involved. In Americas, bat bites are the most common source of rabies infection in humans. Rabies is caused by lyssaviruses including rabies virus and Australian bat lyssavirus. Disease produces almost fatal enc...

Citations

... This term (Rheumatoid arthritis) is based on the Greek for watery and sore joints. A affects about 24.5 million people of the worlds in 2015 (Murtaza et al, 2018). This is between 0.5 and 1% of adults in the urban globe with 5 and 50 per 100,000 new cases is developing the condition each year (Smolen et al, 2016). ...
... The physical problems of GC include dyspepsia, heart burn, anorexia, abdominal pain, nausea, vomiting, weight loss, and elimination-related problems. [5] In addition to physical problems, acute psychological distress manifested by depression and anxiety is also quite common among patients with GC. [6] These patients also have a wide range of physical, psychological, and educational needs [6][7][8] which are usually fulfilled ineffectively. Unfulfilled needs in these patients negatively affect the different aspects of their quality of life. ...
... Similarly, Unger et al. suggested that in PD patient not only gut microbiota but also SCFA concentration is found to diminish. They also found reduction of acetate, propionate and butyrate in the fecal sample of PD patient thereby reducing the SCFA and might be liable for inducing alterations in ENS and causes GI dysmotility in PD [55]. The gut bacteria's helps to breakdown the dietary fibers and produces SCFA such as acetate and butyrate are the major products of the bacterial fermentation of carbohydrates and proteins in the gut [56]. ...
... [4,5] Initial presenting features may include erythema not sharply demarcated, edema, tenderness, skin lesions, blister formation, ulceration, necrosis, crepitus, pain out of proportion, and subcutaneous tissue induration. [1,6] Overlying tissue may appear unaffected despite underlying fascial infection. [6] Surgical intervention is the only definitive modality to differentiate between NF, myositis, and pyomyositis. ...
... Left untreated, thalassemia major patients die mostly from heart failure. [15] Qualitative hemoglobin disorders are caused by mutations that distort the normal globin 3-dimensional structure. [16] The glutamate to valine at the sixth amino acid position on the β-globin subunit. ...
... The breast cancer tissues are created by the breast cancer generally [3]. There are some common symptoms exhibited by the females suffering from breast cancer, these symptoms include breast irregularities, skin dimpling especially across the affected area, a trade in the shape of breast, inverted nipple all of a sudden, oozing liquid from the areolas and nipples, scaly patch which appears purplish [4]. ...
... Di Belgia pada tahun 2016, seorang gadis berusia 3 tahun meninggal karena difteri. Pada bulan Juni, Juli 2016, terdapat 22 kasus difteri dengan 5 meninggal karena difteri di Malaysia (Mustafa et al., 2016). Di Yaman, di mana perang saudara telah berlangsung sejak Maret 2015, wabah besar difteri diketahui pada Oktober 2017 dan Mei 2020, wabah difteri masih berlangsung (Badell et al., 2021). ...
... Inflammation is mostly present in the midbrain and medulla in furious stage and the spinal cord in paralytic rabies stage. The virus spreads from the brain to many tissues and organs, replicates in salivary glands and excreted in saliva (Mustafa et al. 2015). ...