Allen D. Seftel’s research while affiliated with Cooper University Hospital and other places

... In the past decades, several studies across different medical disciplines have indicated the therapeutic efficacy of ESWT to various degrees against diverse medial conditions, including spasticity after upper motor neuron injury [26], tendinopathies, musculoskeletal conditions and soft tissue disorders [27][28][29][30][31][32], refractory angina pectoris [33], erectile dysfunction [34], and sexual conditions other than erectile dysfunction [35,36]. While several studies have also suggested that the use of ESWT exerts a beneficial effect in patients with CP/CPPS [8,[15][16][17][18][19][20][21][22][23][24], as with erectile dysfunction [37], the application of ESWT in the management of CP/CPPS is not without its controversies [23,25]. ...

Reference:

Extracorporeal Shockwave Therapy (ESWT) Alleviates Pain, Enhances Erectile Function and Improves Quality of Life in Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome

... In the case of earlystage prostate cancer, for example, patients and clinicians must carefully consider the patients' capacities and preferences when choosing among alternative treatment choices, including active surveillance, surgery, or various forms of radiation treatment [24,25]. Thus, promoting patients' autonomy in urological decision-making is crucial, and implementation of SDM is demanded by current urological and urooncological treatment guidelines [26][27][28]. Consistently, a survey among German urologists indicated that 84% consider SDM the preferred method of patient-clinician communication [29]. ...

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Power asymmetry and embarrassment in shared decision-making: predicting participation preference and decisional conflict

... The USA Government provides funding and support for the Office on Women's Health (OWH), which coordinates women's health initiatives across the Department of Health and Human Services. To demonstrate and prioritize the social and economic importance of MRH, legislation should be passed to establish an Office on Men's Health (OMH) with the vision of: 'all men and boys achieve the best possible health' (Miner et al., 2018). For men's overall and reproductive health care seeking and needs to be met, there must be an investment by the government to formulate policy changes and provide funding to support reorientation of men's health care services (Shand and Marcell, 2021), and that starts with identifying how men best communicate. ...

Reference:

Current global status of male reproductive health

... [26][27][28] Other studies report on recurrent complications related to this treatment, like infection of the stent-graft with the need to convert to open surgery. 6,[29][30][31] However, all of these studies did not determine the rate of stent-graft infection and recurrent bleeding. In our study, we used endovascular treatment in 80% of our patients. ...

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Endovascular and open surgical options in the treatment of uretero-arterial fistulas

... Failure was assumed to be associated with the peripherally acting nature of epelsiban. However, interest in the inhibition of both central and peripheral oxytocin receptors in the treatment of PE remained, leading to research on another oxytocin antagonist, cligosiban 6 . ...

Reference:

Oxytocin antagonists: the next frontier in PE treatment

... Surveillance rectal swab is performed in various hospitals worldwide to monitor the gut colonization by MDR bacteria during long-term hospitalization. Diverse studies in the last year showed how these surveillances provide valuable information to clinicians [95,96], helping them define the empirical treatment for severe diseases such as sepsis and preventing post-operatory or trauma-related infections, besides informing about MDR dissemination through colonization [97][98][99]. The current problem is how to refine the methods to enable the search of multiple pathogens, including non-MDR, to prevent infection in intensive care units and hospital wards. ...

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Virulence Profile, Antibiotic Resistance, and Phylogenetic Relationships among Escherichia coli Strains Isolated from the Feces and Urine of Hospitalized Patients

... In the European Male Ageing Study (EMAS), only three sexual symptoms (poor morning erections, low frequency of sexual thoughts and erectile dysfunction) showed a clear Table 4 Signs and symptoms potentially indicative of (acquired) testosterone deficiency in ageing men [12 for review] Sexual symptoms -Decreased sexual desire (libido) -Decreased sexual thoughts -Decreased sexual activity -Decreased frequency of morning erections -Erectile dysfunction General physical symptoms -Fatigue -Lack of energy -Decreased work capacity, vitality, strength -Hot flushes -sweats -Decreased general wellbeing Psychological and neurological symptoms -Depressed mood -Poor motivation, initiative -Poor self-confidence -Mood changes, irritability -Poor concentration -Impaired short-term memory -Sleep disturbances -daytime sleepiness Physical signs -Decreased lean muscle mass -Decreased muscle strength, sarcopenia -Increased (abdominal) adiposity -Gynecomastia -Decreased testis volume -Loss of facial, axillary, pubic hair -slow beard growth -Unexplained anaemia (mild, normocytic, normochromic) -Height loss -low bone mineral density -osteoporosis -Frailty interview (Androtest) concentrating on sexual symptoms showed a somewhat better specificity (~ 65-70%) to predict low T in a specific population of patients consulting with sexual dysfunction [40,41]. For the Sexual Arousal, Interest, and Drive Scale [42,43] and the Hypogonadism Impact of Symptoms Questionnaire [44], which have been more recently developed, available clinical data is limited and obtained more in the context of treatment-outcome measure than as diagnostic tool. ...

Reference:

Diagnosis of hypogonadism in ageing men

... The practice of physical activity was assessed using the physical activity scale for individuals with physical disabilities score (10). Low total testosterone was defined as ≤ 300 ng/dL (11). The diagnostic criteria outlined by the international consensus for MASLD were applied (8). ...

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Low testosterone is associated with steatosis in the male population with spinal cord injury

... The results of this study was limited by the characteristics of study participants. The study did not include men with severe LUTS, who were the main concern in prescribing testosterone replacement 38 . Since the problem remains unsolved, patients with LUTS should be treated carefully regarding testosterone replacement therapy. ...

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Factors Associated with Bothersome Lower Urinary Tract Symptoms in Middle-Aged Men Receiving Health Checkup

... Clinical trial proved that the tadalafil once daily treatment could be used to maintain cavernosal tissue integrity. More trials confirm that state [30][31]. Moreover, one of these studies proved that stretched penile length was significantly more retained after tadalafil once a day than after a placebo [31]. ...

Reference:

After Radical Prostatectomy: Erectile Dysfunction Diagnosis and Its Treatment - A Literature Review