Alize J. Ferrari's research while affiliated with The University of Queensland and other places
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Publications (58)
Background:
The Global Burden of Disease Study (GBD) estimates burden by cause with major relevance for resource allocators globally. Non-fatal burden estimates are influenced by disorder severity. However, for many disorders, global severity is sourced from a single high-income country survey. We aimed to estimate severity distributions that vary...
Objective:
To investigate the associations between low education and risk of mental disorders, substance use disorders and self-harm in different age-groups.
Methods:
All subjects in Stockholm born between 1931 and 1990 were linked to their own or their parent's highest education in 2000 and followed-up for these disorders in health care registe...
Background
Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading cause...
Background
Mental disorders (MDs) are known risk factors for suicide. This systematic review updates the evidence base for this association and improves upon analytic approaches by incorporating study-level and methodological variables to account for measurement error in pooled suicide risk estimates.
Methods
A systematic review was conducted to r...
Summary
Background
Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a sta...
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countr...
Background:
In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publ...
Background
Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardise...
This paper estimated mortality for 282 causesof death in 195 countries from 1980 to 2017, adding 18 causes to its estimates compared to GBD 2016. In 2017, the GBD study added numerous data sources, including 127 country-years of vital registration data and 502
country-years of cancer registry data.
Background
The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has le...
Background
The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has le...
Background
How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifi...
Background
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved method...
Summary
Background: How long one lives, how many years of life are spent in good and poor health, and how the population’s state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which...
Summary
Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improv...
Background:
Alcohol and drug use can have negative consequences on the health, economy, productivity, and social aspects of communities. We aimed to use data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 to calculate global and regional estimates of the prevalence of alcohol, amphetamine, cannabis, cocaine, and op...
Background:
The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the impo...
Background: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of “leaving no one behind”. Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016...
Background: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study...
The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of add...
Background: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years l...
Background: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluat...
eFigure 1. Socio-Demographic Index quintiles by GBD subnational level 1 geography, 2015
eFigure 2a. Top 25 Global Causes of Death, by 5 SDI quintiles and 21 GBD regions, Aged 0-6 days, Females & Males, 2015
eFigure 2b. Top 25 Global Causes of Death, by 5 SDI quintiles and 21 GBD regions, Aged 7-27 days, Females & Males, 2015
eFigure 2c. Top 25 Glob...
The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow a...
Progress towards the Sustainable Development Goals.
BACKGROUND:
In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015).
ME...
This methods appendix provides further methodological detail for the health-related Sustainable Development Goals (SDGs). The appendix is organized into broad sections following the structure of the main paper. The supplementary results offer additional results tables and figures, as well as more detailed methodological figures.
The supplementary results offer additional results tables and figures, as well as more detailed
methodological figures.
Citations
... 9 In children and adolescents, mental health conditions are a major cause of morbidity 10 and are increasingly prevalent. 11 Since the COVID-19 pandemic, a global increase has been reported in young people presenting at accident and emergency departments (A&E) for self-harm and other psychiatric emergencies. 12 Post-discharge mental health follow-up for these young people is crucial. ...
... Parametric dental models, which describe shape and position variations of dental models in a population, also have broad applications in digital dentistry, such as teeth segmentation [11], dental mesh repairing [12] and 3D teeth reconstruction [13,7]. The construction of paramet-ric dental models involves the following steps [14,15]: (1) rigidly aligning all the dental models to a common space, (2) estimating the point-to-point correspondence between the aligned dental models and (3) employing Principal Component Analysis (PCA) [16] to determine subspaces of the parametric dental models. However, the accuracy of existing parametric dental models is limited due to the lack of an unbiased dental template, which is essential for precise spatial alignment and point-to-point correspondence estimation. ...
... Interpersonal factors such as suicide attempts being seen as attention seeking [22,29] and the impact of relationship breakup [21], as well as traditional masculinity norms as a barrier to help-seeking [2] potentially, contribute to suicidal behaviours in LMICs. Recent studies have emphasised mental disorders (MDs) [30,31] as well as mental and substance use disorders [32] as the mounting risk factors for suicide. A recent study focused on the lack of treatment coverage and underdiagnosis status of major depressive disorders in LMICs [33], highlights the ways in which support of mental health conditions create potential threats for deaths by suicide. ...
... The global burden of ischemic heart disease (IHD) has been increasing steadily since 1990 and transferred from a global health threat to primarily affecting low-and middle-income countries, including China ( Roth et al., 2020 ). In 2019, IHD was the second leading cause of death in the Chinese population, accounting for 17.6% of all deaths and 9.1% of disabilityadjusted life years, and this proportion will continue to rise in the future ( Murray et al., 2020 ). Changes in population dynamics or environmental risk factors may play a role in the development of IHD ( Virani et al., 2020 ). ...
... As the primary ambient air pollutants in urban settings, fine particulate matters with aerodynamic diameter ≤2.5 μm (PM 2.5 ) and ozone are the top leading environmental threat of global heath, resulting in 4.5 million premature deaths in 2019 [1]. Associations of long-term survival with PM 2.5 and ozone exposure have been broadly investigated in North America and Europe [2][3][4], whereas longitudinal research from low-and middle-income countries (LMICs) is still at the infancy stage owing to a lack of wide-coverage ground-based measurements and well-established population cohorts. ...
... Depression gives rise to a large proportion of the health burden from mental disorder and substantially diminishes quality of life with an increased prevalence across the globe (Moreno-Agostino et al., 2021;Vos et al., 2020). Given the social and health care burden of this disorder, it is imperative to identify modifiable risk factors for prevention of depression. ...
... Overweight and obesity in Latin America children and adolescents has increased considerably in recent years. [1] Regarding Chile, 27% overweight and 31% obesity were estimated in this population in 2021, [2] indicating an alarming public health situation because they are important risk factors for hypertension, [3] 2 Godoy-Cumillaf et al. • Medicine (2023) 102: 21 Medicine diabetes mellitus, [4] cardiovascular diseases, [5] some types of cancer, [6] and premature death. [7] Physical activity (PA) interventions have been a proven effective means to prevent or treat overweight and obesity and thus improve health-related values in children and adolescents. ...
... Prior to differential gene expression analysis, samples from raw meta-file were independently quantile normalized based on the microarray platform used. Illumina, single-channel Agilent, and Affymetrix datasets were normalized using lumi (Du et al., 2008), limma (Ritchie et al., 2015), and Affy (Gautier et al., 2004) packages respectively. The normalized data was further batch corrected using ComBat (Leek JT, Johnson WE, Parker HS, Fertig EJ, Jaffe AE, Zhang Y, Storey JD, 2020) and subjected to differential gene expression analysis (DGEA) using limma. ...
... Depression can affect cognitive functions, and there are many people with depressive symptoms and cognitive decline in the aging population [1,2]. Taiwan became an aging society in 2018. ...
... Meanwhile, stroke was the third-leading cause of death and disability combined and the second-leading cause of global death in 2017 (G.D.a. H. Collaborators, 2018). As the burden of most NSDs increased with age (Sundquist et al., 2004), an increasing number of people are reaching an age where they are likely to experience neurological illness due to the growth of the population and an ageing population worldwide (G.N. ...