Alice F Murray's research while affiliated with Boston Medical Center and other places

Publications (19)

Article
Full-text available
Objectives: Few studies of point-of-care ultrasound training and use in low resource settings have reported the impact of examinations on clinical management or the longer-term quality of trainee-performed studies. We characterized the long-term effect of a point-of-care ultrasound program on clinical decision making, and evaluated the quality of...
Article
Full-text available
The utility of point-of-care ultrasound is well supported by the medical literature. Consequently, pediatric emergency medicine providers have embraced this technology in everyday practice. Recently, the American Academy of Pediatrics published a policy statement endorsing the use of point-of-care ultrasound by pediatric emergency medicine provider...
Article
SonoGames was created by the Academy of Emergency Ultrasound for the 2012 annual meeting of the Society for Academic Emergency Medicine. The assessment of resident knowledge and of the performance of point-of-care ultrasound examinations is an integral component of ultrasound education and is required in emergency medicine residency training. With...
Article
The value of point-of-care ultrasound education in resource-limited settings is increasingly recognized, though little guidance exists on how to best construct a sustainable training program. Herein we offer a practical overview of core factors to consider when developing and implementing a point-of-care ultrasound education program in a resource-l...
Article
Ultrasonography is of growing importance within internal medicine (IM), but the optimal method of training doctors to use it is uncertain. In this study, the authors provide the first objective comparison of two approaches to training IM residents in ultrasonography. In this randomised trial, a simulation-based ultrasound training curriculum was im...
Article
This review describes ultrasound techniques of potential use to high altitude researchers and discusses technical issues related to using ultrasound for high altitude research. Ultrasound allows portable, noninvasive evaluation of many physiologic parameters of interest to high altitude researchers. We discuss techniques that have been extensively...
Article
Point-of-care ultrasound is being increasingly implemented in resource-poor settings in an ad hoc fashion. We developed a focused maternal ultrasound-training program for midwives in a rural health district in Zambia. Four hundred forty-one scans were recorded by 21 midwives during the 6-month study period. In 74 scans (17%), the ultrasound finding...
Article
Full-text available
Increased intracranial pressure is suspected in the pathogenesis of acute mountain sickness (AMS), but no studies have correlated it with the presence or severity of AMS. We sought to determine whether increased optic nerve sheath diameter, a surrogate measure of intracranial pressure, is associated with the presence and severity of AMS. We perform...
Article
Sonographic B-lines, also known as lung comets, have been shown to correlate with the presence of extravascular lung water (EVLW). Absent in normal lungs, these sonographic findings become prominent as interstitia and alveoli fill with fluid. Characterization of the dynamics of B-lines, specifically their rate of disappearance as volume is removed,...
Article
Objectives: Sonographic thoracic B-lines and N-terminal pro-brain-type natriuretic peptide (NT-ProBNP) have been shown to help differentiate between congestive heart failure (CHF) and chronic obstructive pulmonary disease (COPD). The authors hypothesized that ultrasound (US) could be used to predict CHF and that it would provide additional predict...
Article
The comet-tail technique of chest ultrasonography has been described for the diagnosis of cardiogenic pulmonary edema. This is the first report describing its use for the diagnosis and monitoring of high-altitude pulmonary edema (HAPE), the leading cause of death from altitude illness. Eleven consecutive patients presenting to the Himalayan Rescue...
Article
Studies on the neurologic effects of high-altitude travel have focused on psychometric and cognitive testing and the long-term effects of hypoxia on memory and cognition. Few authors have discussed overt clinical psychiatric illness during high-altitude travel, and those few have focused on patients with preexisting psychiatric diagnoses. We descri...
Article
Vascular thrombosis is an uncommon but recognized peril of high altitude travel. Traditionally, this has been associated with prolonged exposure to extreme altitudes where dehydration, hemoconcentration, cold, use of constrictive clothing, and enforced stasis due to severe weather have been named as contributing factors. It is widely hypothesized t...
Article
High altitude pulmonary edema (HAPE) is the leading cause of death from altitude illness and rapid descent is often considered a life-saving foundation of therapy. Nevertheless, in the remote settings where HAPE often occurs, immediate descent sometimes places the victim and rescuers at risk. We treated 11 patients (7 Nepalese, 4 foreigners) for HA...
Article
We sought to determine if optic nerve sheath diameter (ONSD), a surrogate measure of ICP, is increased in high altitude pulmonary edema (HAPE). Five HAPE patients (one with a codiagnosis of high altitude cerebral edema [HACE]) treated at the Himalayan Rescue Association clinic in Pheriche, Nepal (4240 m), underwent optic nerve sheath ultrasonograph...

Citations

... A standardized scoring system was used to grade image quality on a scale of 0 to 4 (0: no meaningful images; 1: poor, not sufficient for interpretation; 2: good, acceptable for interpretation; 3: excellent, minor suggestions for improvement; and 4: outstanding, no suggestions for improvement). This scoring system is currently in use in the Kenya rural ultrasound training program [9] as well as other similar training programs in the African region [14,15] (Additional file 1: Appendix A). ...
... Cardiac POCUS is a focused ultrasound-based imaging strategy performed by a healthcare provider at the bedside to identify a limited list of cardiac findings which could be the etiology of the patient's often critical presentation. Typically limited to qualitative, binary assessments of systolic function and the presence of pericardial fluid, cardiac POCUS is not comprehensive nor consultative cardiac imaging, e.g., echocardiography [5][6][7]. Multiple single center pediatric research studies show noncardiologists utilizing cardiac POCUS, predominantly as a screening tool, to diagnose depressed systolic function with reasonable accuracy compared to the gold standard of echocardiography [7][8][9][10][11][12]. These studies are either evaluations of specific cardiac POCUS training programs for noncardiologists [9,10,12] or they are evaluations of cohorts of credentialed cardiac POCUS providers working within POCUS imaging programs [7,8], typically compromised of longitudinal training prerequisites, credentialing systems, image storage and reporting, and quality assurance programs. ...
... Despite advantages for resource-limited settings, few reports of LUS training programs in low-and middle-income countries (LMICs) exist (2)(3)(4)(16)(17)(18)(19). All LMIC LUS training programs were led by experts using a multifaceted curriculum of lectures, handson instruction, and practice examinations. ...
... Building on the gamification movement, a competitive gamification approach for point-of-care ultrasound (POCUS) was first popularized by the SonoGames competition that began at the Society for Academic Emergency Medicine Annual Meeting in 2012. 9 The basis of this competitive event was to use games and competition-based learning as a tool for resident ultrasound education. Results from this and other gamification events have shown an increase in resident enthusiasm for POCUS learning. ...
... Further, POCUS skills can be difficult to retain without ongoing practice and mentorship support. 5 Rural practitioners are typically "generalist" family physicians who combine family medicine with hospital-based practices such as obstetrics, EM and inpatient care. They often work in low-volume settings with few opportunities to use POCUS for clinical care, and most do not have access to local POCUS mentorship. ...
... Several authors have investigated how the use of videos, manuals, simulators, and other aids promote self-learning, self-direction, self-efficacy, self-monitoring, and selfevaluation in students to achieve learning; all of these are components of self-regulation [16,19,2,17,18]. However, these research investigations have been conducted through an implicit process. ...
... Solar-powered panels utilize mechanical motors requiring additional power for the reflectors [19]. The mechanical motors generate noise that cannot be removed during image processing for patient images [20,21]. ...
... 3,7 The use of point-of-care ultrasound (POCUS) in evaluating interstitial edema has been shown to be highly sensitive and specific for the evaluation of both cardiac and non-cardiac pulmonary edema. [8][9][10][11][12] Previous studies have also shown an association between geographical elevation and the development of non-cardiac pulmonary edema on ultrasound through identification of B-lines (previously "comet tails"). [13][14][15] Advances in portability and the reduced cost of POCUS units have introduced an opportunity for its application in screening for subclinical interstitial edema at altitude. ...
... Increased confidence, scanning frequency and impact on patient outcomes and management (as perceived by the clinicians) were described by the trainees as a result of the training; improvement in patient management and clinical diagnoses was reported by 62% of trainees, and earlier diagnoses and changes to patient management was reported by 46% of trainees. Other studies evaluating obstetric PoCUS training report similar improvements in pre-post course testing [56][57][58][59], trainee confidence [60][61][62][63], and knowledge retention [36,56,64]. ...
... This basic examination diagnoses the majority of life threatening conditions like pericardial tamponade, wall motion abnormality and hypovolemia. Repeated examinations allow us to monitor therapeutic intervention and patient progress [22]. Qualitative measure of ejection fraction of left ventricle can be estimated by observation and is comparable to quantitative measures [23]. ...