Ali Ghafir’s scientific contributions

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Publications (3)


Prevalence of IgM and IgG Antibodies to Toxoplasma gondii in females and males in Benghazi city-Libya
  • Article
  • Full-text available

July 2022

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53 Reads

Khyber Medical University Journal

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Khadija Saeed

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Nesrine Miloud Al-Awkally

The protozoan Toxoplasma gondii is one of the most common infectious pathogenic parasites and can cause severe medical complications in infants and immune-compromised individuals. The current study was done in Benghazi, Libya from January to September 2020. This study was done on a total of 260 people attending private laboratories. Latex agglutination test (LAT) and enzyme linked immunosorbent assay (ELISA) were used to detect the prevalence of anti-Toxoplasma IgM and IgG antibodies, The present study showed that the positive diagnosis of Toxoplasma gondii infection was only in females, and the different between the sexes was observed. The highest ratio of IgM antibodies was in age group 31 to 40, n=12 (7%), followed by 21 to 30, n=9 (5%). Toxoplasma infections were higher in autumn 151 (90%) followed by summer 14 (8%) while the lowest was recorded in spring 2 (1%). To avoid human infection, all meat should be cooked well and fruits and vegetables washed before eating, protection such as wearing gloves and washing hands should be taken through and after gardening to avoid connection to the soil polluted with T. gondii oocytes expelled in cat feces, and 291 consumption of dirty water should be evaded, especially in developing countries. Future studies are required to determine the prevalence of Toxoplasma gondii antibodies in more people by using ELISA methods.

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Prevalence of IgM and IgG Antibodies to Toxoplasma gondii in females and males in Benghazi city-Libya

March 2022

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110 Reads

The protozoan Toxoplasma gondii is one of the most common infectious pathogenic parasites and can cause severe medical complications in infants and immune-compromised individuals. The current study was done in Benghazi, Libya from January to September 2020. This study was done on a total of 260 people attending private laboratories. Latex agglutination test (LAT) and enzyme linked immunosorbent assay (ELISA) were used to detect the prevalence of anti-Toxoplasma IgM and IgG antibodies, The present study showed that the positive diagnosis of Toxoplasma gondii infection was only in females, and the different between the sexes was observed. The highest ratio of IgM antibodies was in age group 31 to 40, n=12 (7%), followed by 21 to 30, n=9 (5%). Toxoplasma infections were higher in autumn 151 (90%) followed by summer 14 (8%) while the lowest was recorded in spring 2 (1%). To avoid human infection, all meat should be cooked well and fruits and vegetables washed before eating, protection such as wearing gloves and washing hands should be taken through and after gardening to avoid connection to the soil polluted with T. gondii oocytes expelled in cat feces, and 291 consumption of dirty water should be evaded, especially in developing countries. Future studies are required to determine the prevalence of Toxoplasma gondii antibodies in more people by using ELISA methods.


Variation in thyroid hormone levels among children in Benghazi city -Libya

January 2021

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55 Reads

Advanced Pharmaceutical Bulletin

Thyroid hormones play a vital part in development, of metabolism, nervous system myelination, and organ functions. Thyroid complaints can be tough to identify clinically, but thyroid function tests can assist in making a diagnosis. Evaluating thyroid stimulating hormone is the major step. If it is abnormal, free thyroxin should be measured. An elevated concentration of thyroid stimulating hormone with a low concentration of free thyroxin suggests hypothyroidism. A low concentration of thyroid stimulating hormone with a great concentration of free thyroxin suggests hyperthyroidism. A cross sectional study was done in children attending to Pediatric hospital- Benghazi for one year from January 2018 to December 2018. Total of 221 children, 94 (43%) were males and 127 (57%) were females attending the hospital for thyroid hormone test were included in the study. Secondary data on gender, TSH, T3 and T4 level were analyzed. Thyroid diseases reported was found to be more prevalent in females than males. T4 was higher in females than males by percentage 8 (4%) to 5 (2%) respectively. TSH was also has a higher rate recorded in females than males by percentage 38 (17%) to 28 (13%) respectively. It can be concluded from the present study that the gender has a significant effect on the levels T4, T3 and TSH. Initial analysis and treatment are important to avoid irreparable and enduring nervous system injury and progressive interruption, specifically in newborns as they are very in danger to thyroid dysfunction.