Alessandro Porro’s research while affiliated with University of Milan and other places

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Publications (88)


Forensic toxicology backdates the use of coca plant (Erythroxylum spp.) in Europe to the early 1600s
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October 2024

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Journal of Archaeological Science

Gaia Giordano

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Mirko Mattia

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Cristina Cattaneo

Vitamin D deficiency, pregnancy, and childbirth in early medieval Milan
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  • Full-text available

October 2024

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30 Reads

Journal of Archaeological Science

Download

A case of "distillation" of human heads in the Eighteenth Century for medicinal purposes resulting in calcination of the cranium

May 2024

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13 Reads

Carlo Gandini (1705-1788) is known for the introduction of typical traditional Chinese Medicine practices into Italian medicine, and in particular, that of pulsology. Yet, his activity led him to perform other interesting experimentations, among which, human head distillation. Distillation from human heads was performed since the 17 th century and permitted the obtention of an elixir prescribed to treat encephalic diseases. In this paper, we present his analysis, the result of his experimentation and what appears to be the first evidence of cremation, albeit unintentional, some one hundred and forty years before the first modern cremations.



Orthopedics between Milan and Mexico: A case from the late 19th century

December 2023

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4 Reads

A folder titled "Rovatti" was found among the documentation of the private collection of Enrico Rosmini in Milan. This folder contained correspondence related to the Pio Istituto dei Rachitici in Milan, a school dedicated to the care of children with skeletal deformities. These documents provide insight into the care of the patients of the Institute through a personal lens, that of the experience of a father struggling with his efforts to achieve financial security. The documents presented in this short paper constitute additional information to better reconstruct the history of Milanese medicine in a crucial period of transition towards modernity, the so-called belle époque.


The Singing Brain: Words and Music in the Opera

October 2023

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54 Reads

This chapter provides an overview of the fascinating interplay between opera and the nervous system to elucidate the effects of opera singing on neurophysiology. The first studies on the physiology of the voice and the role of music and singing in opera date back to Hippocrates and Aristotle. At the end of the sixteenth century, several treatises on vocality and the organs of voice and speech were published by different anatomists, just as the “Florentine Camerata” began its activities, which culminated in the creation of the first opera. Since then, the effects of opera singing on the brain have not ceased to attract interest from researchers. Extensive vocal training in opera, a multimodal artistic genre based on the interaction of different sensorimotor components, can have profound effects on neuroplasticity. Spending years in training and practicing this highly specialized and multisensorial artistic genre can induce functional and structural adaptations in the human brain. These experience-dependent changes during singing mostly involve regional neuronal networks engaged in motor control of vocal activity and multimodal sensory integration, including auditory and sensorimotor regions and the insula. Further neuroimaging and neurophysiological studies conducted in larger samples and adopting complementary approaches (e.g., fMRI, tractography, and morphometry) are required to elucidate in greater detail the effects of opera singing on the structure and functions of the brain.


Neuro-Musicology of Opera

October 2023

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57 Reads

This chapter provides an overview of the main studies available in the scientific literature that have investigated the effects of opera on the human brain and its possible application for the treatment of different health problems. Opera includes several components that make it an all-encompassing artistic form and a source of multimodal sensory stimulation for the human brain. Thanks to the profound interaction between its various components, opera can evoke emotions and heighten their expression as signified by the text and presented in the staged action. The exact mechanisms underlying the intense emotional response it evokes in the spectator are still far from being fully elucidated. They probably include the activation of the human mirror neuron system and the cerebral areas underlying language, action, and music and their ability to express meaning and emotions. The effects of opera on music-induced emotions and their physiological correlates could be used for the treatment of health problems. Despite some intriguing data, the studies evaluating the effectiveness of “opera therapy” are scarce and almost exclusively confined to the treatment of dementia. Future research in this field should clarify the psychophysiological effects of opera as a whole artistic experience and each of its components. Further studies are warranted to identify which health disorders may especially benefit from “opera therapy” and whether there are differences in clinical effectiveness compared to other music therapies.


“Va Sossopra Il Mio Cervello” (My Brain Goes Up): Neurology and Psychiatry in the Opera

October 2023

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24 Reads

From its beginning, opera has frequently represented mental illness, madness, and other neurological conditions. Evaluating how these disorders have been depicted in operas over the centuries allows us to shed a fascinating light on the cultural, social, and medical attitudes and beliefs towards psychiatric and neurological disorders in various historical periods. In the past, madness and other neuropsychiatric disorders were interpreted and, therefore, represented on stage according to nosological theories that are no longer valid and do not correspond to current nosographic classifications. At the beginning of musical theater, alongside the concept of melancholic temperament (derived from the ancient theory of the humors and revisited in the “theory of affects”), mental disorders and madness were perceived and represented according to the concept of passiones animi (“passions of the soul”). Towards the end of the nineteenth century, in parallel with the development of modern neuropsychiatry, the representation of madness progressively assumed a more modern connotation and began being regarded as a true neuropsychiatric, pathological disorder. Other neurological and psychiatric conditions, such as epilepsy, dementia, sleepwalking, hysteria, and psychological blindness, have been frequently represented in different operas over time. Neurological and psychiatric disorders continue to be represented in contemporary operas, which can effectively convey emotional states and increase public awareness of these medical conditions.




Citations (27)


... The CAL is a large osteological collection constituted of over 7,000 skeletons, including about 5,000 from archaeological sites in Lombardy and in particular the urban center of Milan, and 2,127 unclaimed contemporary skeletal remains from the CAL Milano Cemetery Skeletal Collection available for research and didactic purposes in accordance with Italian law (Cattaneo et al., 2018;Viero et al., 2021). The study sample is part of an ongoing research project aiming to reconstruct the lifestyle of the inhabitants of Milan over the last 2,000 years (Biehler-Gomez et al., 2024, 2023b, 2023aGiordano et al., 2023;Mattia et al., 2021) and were selected from the collection based on several criteria: fusion of the coxal bones for a reliable estimation of sex, equal distribution among the five historical periods established for the study (50 skeletons per period) and same number of male and female individuals (125 females and 125 males). As a result, the sample is composed of 50 skeletons per historical period (25 females and 25 males), defined as follows: Roman era (2nd-5th century CE) from the necropolis below the Università Cattolica (dated 3rd-5th century CE), Early Middle Ages (6th-10th century CE) and Late Middle Ages (11th-15th century CE) from the emergency excavations of Sant'Ambrogio and Via Necchi (with stratigraphic units spanning from the 1st century CE to the 15th century CE), Modern era (16th-19th century CE) from the mass grave burials in Via Sabotino (dated to the half of the 17th century) and Contemporary era from unclaimed cemetery individuals who died in the second half of the 20th century ( Table 1). ...

Reference:

Physical activity over 2,000 years in Milan: Using entheseal robusticity as indicator of occupational stress
Forensic toxicological analyses reveal the use of cannabis in Milano (Italy) in the 1600's
  • Citing Article
  • December 2023

Journal of Archaeological Science

... This study is part of an ongoing project on the reconstruction of the life of the Milanese throughout history , 2022a, 2022b, 2023a, 2023cGiordano et al., 2023;Mattia et al., 2021). The skeletal remains in the present paper are part of the CAL (Collezione Antropologica LABANOF -Anthropological Collection of the LABANOF), currently under study at the Laboratory of Forensic Anthropology and Odontology (LABANOF) and housed at the University of Milan (Cattaneo et al., 2018). ...

Papaver somniferum in seventeenth century (Italy): archaeotoxicological study on brain and bone samples in patients from a hospital in Milan

... Synesthesia is a neurological disorder in which the actions of one sensory or cognitive system cause automatic experiences of another sensory or cognitive system (Lorusso et al., 2022). This neurological quirk ushers in a singular communication between senses, thwarting one's concept of how the brain receives stimuli. ...

Synesthesia and Emotional Sound

... Furthermore, complications like pneumonia or congestive heart failure, as well as long-term hospital admissions that could lead to hospital-acquired infection, can exacerbate morbidity and raise costs [14,15]. These significant, clinical and economic repercussions, combined with widespread access to vaccines, establish vaccination as the most effective preventive measure [13,[16][17][18][19][20][21][22][23][24][25]. In Italy, influenza vaccination is recommended for healthcare professionals, the hospitalized elderly, those over 60, and young children aged between 6 months and 6 years old [26]. ...

The first major vaccination campaign against smallpox in Lombardy: the mass vaccination campaign against coronavirus…nothing new…only terminology

... First, a drastic change in respiratory syncytial virus epidemiology, the main cause of bronchiolitis [10,11]. Second, a decrease in breastfeeding practice, a protective factor against severe bronchiolitis [12][13][14]. Finally, older siblings, who had not been exposed to respiratory viruses during the initial pandemic phase, might have facilitated an increased viral transmission after the relaxation of preventive measures in the following years [15,16]. ...

Breastfeeding during a Pandemic

Annals of Nutrition and Metabolism

... The Spaniards, after the invasion of the New World, reported that the Inca Empire took control of all the coca plant crops of the Andes territory thanks to the expansion of the Empire and that all coca leaves collected were delivered to the Inca Royals and used for the religious practices of the entire population. Indeed, the Inca population considered it a miraculous and magical plant that had the power to take away hunger and thirst, produced exhilarating effects, could be used as medicine (as antiseptic and analgesic, to help in digestion, to cure asthma, stomach ache, chest pain and sores, reduce nose bleeding and vomit), and induced a sense of well-being (Bernabè Cobo, 1890;Grinspoon and Bakalar, 1979;Karch, 2017). The Incas knew that chewing coca led to a loss of sensitivity on the tongue; therefore, they hypothesized that this could slow down the decomposition of a body and used a coca tincture for mummification procedures (Karch, 2017). ...

Mercury poisoning in two patients with tertiary syphilis from the Ca’ Granda hospital (17th century Milan)

Archaeometry

... This clear, colorless liquid is characterized by a gasoline like smell. 1 It was first isolated in 1825 by the British scientist, Michael Faraday (1791-1867), who extracted it from a complex mixture obtained as a by product of illuminating gas production. 1 It was used as an ink component in printing, a solvent for organic materials, and substance in the chemical and pharmaceutical industries to produce rubbers, lubricants, dyes, detergents, and pesticides. 1 Nowadays, benzene is used primarily in the manufacture of organic chemicals such as styrene, ethylbenzene, cumene, cyclohexane, and phenol to produce polymers. 1 Benzene is classified as a Group 1 human carcinogen by The International Agency for Research on Cancer (IARC). ...

Benzene and leukemia: from scientific evidence to regulations. A historical example

La Medicina del lavoro

... Die Situation während der Coronapandemie ist nicht mit der Spanischen Grippe oder anderen Pandemien in jüngerer Zeit vergleichbar, da Migranten in der Geschichte der menschlichen Zivilisation noch nie so mobil waren und ein Impfstoff noch nie so schnell verfügbar war (Franchini et al. 2020). Folglich können Wissen und Erfahrungen, die während der Coronapandemie gesammelt wurden, nicht auf Wissen zurückgeführt werden, das während vergangener Pandemien erworben wurde, insbesondere in Bezug auf diese beiden Aspekte. ...

COVID 19 and Spanish flu pandemics: All it changes, nothing changes

... While research into depression and musicians is a relatively recent phenomenon, descriptions of mental health problems within the field have been frequent across the centuries (Cordingly, 2001;Kluge, 1818;Lorusso & Porro, 2020;Rahm, 1994) , as exemplified by Mozart's heroine from "The Abduction from the Seraglio", who is quoted in the title of this article. In fact, descriptions of mental health are so realistic within music, that medical papers have often discussed them as if they were case studies (Chest, 2018). ...

Opera and Neuroscience: A Historical Approach and Its Relevance Today
  • Citing Chapter
  • January 2020

... To test the accuracy of facial reproductions, in the present paper the Authors use the Tenchini collection, which contains wax reproductions of prisoners' faces and their skulls [3]. Tenchini's anatomical collection, today preserved at the Museum and Historical Library of Biomedicine (BIOMED) of the University of Parma, includes: Criminal Anthropology (CA) cards, dried brains, masks, skulls and organs. ...

The Tenchini’s collection: a forensic anthropometric legacy of 19th century Parma, Italy

Forensic Sciences Research