Alan Taberham’s research while affiliated with University of Southampton and other places

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (3)


Fabrication of Lab on Chip devices from fluoropolymers
  • Article

May 2008

·

61 Reads

·

32 Citations

Alan Taberham

·

·

·

Three different rapid manufacturing methods for the construction of fluoropolymer microfluidic devices were investigated: (1) fluoropolymer/epoxy laminate/fluoropolymer structures, (2) fluoropolymer/fluoropolymer structures and (3) fluoropolymer/epoxy laminate/glass structures. The structures are chemically and physically robust and the fluoropolymer constructs can be used for optical wave guiding. Principles behind the use of fluoropolymer waveguide constructs and a basic theoretical analysis of the improvements they offer are presented. The otherwise problematic bonding of the polymers was facilitated by chemical (sodium naphthalene) surface treatment. The effects of the process were characterized by contact angle and bond strength measurements. For demonstration purposes, microfluidic channels were fabricated using Ordyl SY epoxy laminate (methods 1 and 3) and hot embossing of the polymers (method 2). The first method (fluoropolymer/epoxy laminate/fluoropolymer) proved to be the most reliable and successful, in particular when bonding the various layers.



Micro System Technology for Marine Measurement

October 2006

·

25 Reads

·

7 Citations

·

·

·

[...]

·

Alan Taberham

To date the development of in situ chemical and biological sensors has focused on the production of macro instruments for single point deployment. With the exception of oxygen sensors and biological sensors based on fluorometry (that are now commercially available) chemical and biological sensors are not able to make repeated synoptic measurements at finer temporal and spatial scales. This is at odds with the patchiness and temporal variability observed in biogeochemical processes. This paper describes the early stages of development of miniature and mass producible chemical and biological sensors using Micro System Technology. It is hoped that these devices will be suitable for mass deployment and will deliver repeated synoptic data that will allow greater understanding and improved modelling of biogeochemical processes. Initially the production of two devices has been targeted: 1) A miniature cytometer to count and speciate phytoplankton; and 2) A lab-on-a-chip analyser using wet chemistry and optical detection. The production of the analysis chip for the cytometer and a micropump suitable for the lab-on-a-chip analyser are presented here. Preliminary investigations of biofouling are also discussed

Citations (2)


... Optimization of the bacterial cell detachment from filters was required prior to resuspension in the bioanalyzer. A micro fluorescence-activated cell sorting system was developed based on autofluorescence and impedance measurements for detection and characterization of algae (Mowlem et al., 2006). A lF-cytometer based on simultaneous fluorescence at three wavelength ranges and impedance measurements was developed for fast analysis of single phytoplankton (Benazzi et al., 2007). ...

Reference:

1-s2.0-S0079661115000518-main
Micro System Technology for Marine Measurement
  • Citing Conference Paper
  • October 2006

... LOC devices can perform different assays on a micro-scale (e.g., PCR, LAMP, RCA, etc.), since they can integrate all the analytical steps in a single platform [32]. For the development of these platforms, technological advances from the microelectronics industry have been exploited [33]. The basic core of the detection chips, where the biorecognition/analysis takes place, is constructed from glass, quartz, silicon, or polymeric materials, with the latter considered by many to have the most suitable mechanical, chemical, and thermal properties. ...

Fabrication of Lab on Chip devices from fluoropolymers
  • Citing Article
  • May 2008