Abdul-Ameer Jwad Zayer’s scientific contributions

The current research included the preparation of the aqueous and alcohol extract (150 mg/kgB.W) and silver nanoparticles with aqueous and alcoholic extracts (4mg\kg) of cumin (Cuminum cyminum) and used it as antihyperglycemic, antihyperlipidemic, antioxidant and determine its effect on body weight in alloxan induced diabetic rats, sixty healthy rats were enrolled in this study and divided into six groups (10 rats for each group), first group healthy control (negative), other rats were divided randomly to five groups and injected with alloxan (100 mg\kgkgB.W.), second group diabetic positive group and the other diabetic groups were treated with crude aqueous, alcoholic extract of cumin(150 mg\kg), silver nanoparticles with aqueous and alcoholic extracts (4 mg\kg), respectively. The experimental period was 4 weeks and all rats were administered orally. Biochemical test were done by measuring fasting blood glucose, serum insulin, lipid profile (cholesterol, triglyceride, HDL) malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and Catalase (CAT). In addition body weight was determined in all groups. The results indicated that the aqueous extract and aqueous extract with Ag NPs are more effective from alcoholic extract and alcoholic extract with AgNPs for decrease blood glucose, cholesterol and triglyceride while HDL-C increase in diabetic groups treated with aqueous extract and aqueous AgNPs, compared with positive diabetic group. MDA shows decrease while SOD, GPx and CAT levels were increased highly significant, body weight shows significant increase in all groups treated compared with positive diabetic control group.