A.V.N. Appa Rao's research while affiliated with Kakatiya University and other places

... A portion of each heart was taken from all the groups and a 30% w/v homogenate was prepared in 0.9% buffered KCl (pH 7.4) for the estimation of biomarkers (CPK, LDH, SGPT and SGOT) and biochemical parameters (CAT and MDA).The remaining portion of the heart tissue was used for histopathological studies. [13,14] ...

... Without altering heart rate, the extracts increased cardiac output and force of contraction. (Reddy et al.,1990). 24 Pretreatment with T. chebula extract was observed to reduce the impact of the medication on the production of lipid peroxide and maintain the activity of the diagnostic marker enzymes in rats with isoproterenol-induced heart injury (Suchalatha et al., 2004). ...

... The initial paw volume was measured plethysmographycally within 30 s of the injection. The relative increase in the paw volume was measured in control, standard, and treated groups, 4 h after carrageenan injection the percent increase [12,13] in the paw volume in animals treated with standard drug and the three extracts of C. dentata were compared with the increase in paw volume of untreated control animals. ...

... Terminalia chebula fruit is an ingredient of triphala, a well known formulation of ayurveda used as a laxative, hypolipidaemic and antioxidant agent (1-2). Terminalia chebula fruit has also been reported to have adaptogenic (3) and cardiac activities (4), in addition to antiviral and antibacterial (5) actions. Terminalia chebula fruits are an important source of tannin. ...

... The fruit is also used in peptic ulcer, and it is also used in diabetes mellitus, urinary infection, haemorrhages from internal organs, insanity, epilepsy, and other nervous disorders in Ayurveda [14]. The fruit is sweet and traditionally used as a cooling, styptic, antiperiodic, laxative, diuretic, tonic, aphrodisiac, and cardiotonic, and also in jaundice, dyspepsia, urinary calculi, blood disease (e.g., haemorrhages from internal organs), insanity, epilepsy, asthma, diabetes, vitiated conditions of pitta, fever, menstrual disorders, and balancing the body heat [15] (Figure 1). ...

... Acetone extract of Selaginella bryopteris exerted antibacterial activity against gram-positive and negative bacteria Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae (Verma et al. 2015) but in the present investigation no significant antibacterial activity observed in acetone extract of S. bryopteris against Enterococcus faecalis and Escherichia coli which may be due to the selection of different bacterial strains of the said species. Kunert et al., (2008) also studied the antiplasmodial and leismanicidal effects of biflavonoids present in the extracts of Selaginella bryopteris. Previous studies had claimed phenol present in the sporophytic and gametophytic plant body of pteridophytes responsible for antimicrobial activity (Guha et al. 2005) though the phenol content may depend upon the seasonal variation (Ganguly et al. 2013). ...

... In chemical point of view, the presence of lasianthoside-A and lasianthoside-B (two bisdesmosidic C 21 steroidal glycosides) ( Figure S1) was reported by Qiu et al [6]. Similarly, the presence of luteoline-4-O-neohesperiodoside (a known flavone glycoside) ( Figure S2) was reported by Ramesh et al [7]. Steroidal glycosides are extracted from alcoholic extracts [6]. ...

... Pharmacokinetic Interaction between Dapsone and Rifampicin has also been reported by Krishna DR et al who detailed that the dapsone level in blood, its half-life and AUC were significantly decreased with simultaneous increase in plasma clearance when it was administered concomitantly along with rifampicin. 9 This kind of interaction could be a possible cause of adverse drug reaction in the present case. ...

... Phytochemical studies of some Terminalia species have reported the presence of terpenoids and flavonoids (Reddy et al., 1994;Fayez and Mahmoud, 1998;Garcez et al., 2006;Cao et al., 2010). (Kong et al., 1954;Row et al., 1970;Honda et al., 1976a;1976b;Tsuyuki et al., 1979;Anjaneyulu and Rama, 1982;Reddy et al., 1994;Pettit et al., 1996;Conrad et al., 1998;Singh et al., 2004;Garcez et al., 2006;Haque et al., 2008). ...

... This plant is traditionally used as a spice in cooking, salads, and medicine [1]. Consumption of garlic, has been increasing worldwide due to its effectiveness, lower side effects, and relatively low cost [2]. Garlic has been cultivated throughout the world for its tubers which are used for various purposes. ...