A. Singh’s scientific contributions

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Publications (2)


A review on curcuma longa
  • Article
  • Full-text available

February 2012

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1,517 Reads

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20 Citations

Research Journal of Pharmacy and Technology

A. Sri Vasavi Reddy

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H.K.S. Yadav

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A. Singh

Curcuma longa L., (Zingiberaceae) grows up to 3-5 ft tall and has dull yellow flowers. The rhizome is an underground stem that is thick, oblong, ovate, pyriform and fleshy ringed with the bases of old leaves. The plant has oblong, pointed leaves with funnel-shaped yellow flowers. It contains several phytoconstituents belonging to category of alkaloids, glycosides, triterpenoids, sterols, include three curcuminoids: curcumin (diferuloylmethane; the primary constituent and the one responsible for its vibrant yellow color), demethoxycurcumin, and bisdemethoxycurcumin, as well as volatile oils (tumerone, atlantone, and zingiberone), sugars, proteins, and resins. It is popular in indigenous system of medicine like ayurveda, siddha, unani and homeopathy for the treatment of diseases and human ailments. A wide range of biological and pharmacological activities of curcumin has been investigated and is used for its antioxidant, anti-inflammatory, antiviral, antifungal, hepatoprotective, dissolve gallstones, anticarcinogenic, antimicrobial, cardiovascular, gastrointestinal effects, tonic for the digestive system; to dispel worms, strengthen the body, antifertility, menstrual irregularity anti diabetic, antivenom, hypolipidemic, nephroprotective, anticoagulant, anorexia, cough, rheumatism, sinusitis and anti HIV properties. Because of curcumin's rapid plasma clearance and conjugation, its therapeutic usefulness has been somewhat limited, leading researchers to investigate the benefits of complexing curcumin with other substances to increase systemic bioavailability. Numerous in-progress clinical trials should provide an even deeper understanding of the mechanisms and therapeutic potential of curcumin. The present review is therefore, an effort to give a detailed survey of the literature on its properties.

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TABLE 1 : TOTAL PHENOLIC AND FLAVONOID CONTENT
TABLE 5 : FREE RADICAL SCAVENGING ACTIVITY OF ARTEMISIA PALLENS AND ASCORBIC ACID IN DPPH METHOD
TABLE 6 : HYDROXYL RADICAL SCAVENGING ACTIVITY OF ARTEMISIA PALLENS AND GALLIC ACID HYDROXYL RADICAL SCAVENGING ACTIVITY OF ARTEMISIA PALLENS AND GALLIC ACID
FIG. 7: (4, 5 β - Epoxy- 10 β - hydroxy- 1- en- 3-one- trans germacran- 6 α, 12-olide) 
TABLE 7 : ANTIBACTERIAL ACTIVITIES OF THE ETHANOLIC EXTRACTS OF ARTEMISIA PALLENS BY CUP PLATE METHOD

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PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF ARTEMISIA PALLENS

1,641 Reads

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23 Citations

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A Singh

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A Vasavi

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[...]

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S Mary

Artemisia pallens Walls. ex DC, commonly known as Davana, is an aromatic herb found abundantly in humid habitats in the plains all over India. Artemisia pallens is found in Nilgiri hills, and has been used by the tribal people for various ailments. It has been widely used in Indian folk medicine for the treatment of diabetes mellitus. This plant is accredited with antihelmintic, antipyretic and tonic properties and also considered as a good fodder. The oil possesses antispasmodic, antibacterial, antifungal and stimulant properties. The plant has been screened for the antimicrobial, antidiabetic, antinociceptive and wound healing activity. The current study deals with the Phytochemical and Pharmacological of Artemisia pallens. INTRODUCTION: Genus Artemisia (Asteraceae) popularly known as "Sage Brush" or "Worm wood" is bitter aromatics. Artemisia is the largest genus comprising of 400 species widely distributed in South Africa and South America, and 34 species are found in India. This genus is named in honor of Artemis the Greek goddess of chastity. Some of them are sources of volatile oils. Sesquiterpene lactones are known to be present in almost all species 2 .

Citations (2)


... Curcuma Longa Linn (turmeric) is the most important Indian spice and medicinal herb belongs to the Zingiberaceae family which is extensively used in Ayurveda, Unani andSiddha medicine and as polyphenols, responsible for the yellow colour of this rhizome 1,2 . Curcumin activates the DDR (DNA damage response), providing an opportunity and rationale for the clinicalapplication of these nutraceuticals in the chemoprevention of prostate cancer 3 curcumin was having anticancer activities 4 . ...

Reference:

(Print) www.rjptonline.org 0974-360X (Online) Anticancer Activity of Microwave Assisted Polyphenolic Compounds Extracted from Combinations of Curcuma Longa and Camellia Sinensisagainst Lung Cancer Cell Line
A review on curcuma longa

Research Journal of Pharmacy and Technology