A. Pilzecker’s scientific contributions

... In line with this, Dudai and Eisenberg [12] and Alberini [3] proposed the existence of multiple waves of consolidation processes that are initiated after acquisition and can be modulated by either implicit (internal reactivations) or explicit reactivations (cued-recall) instead of only one time window where the memory is labile and afterward stabilized. Thus, in the present study, we aim to dissect the temporal dynamics of the consolidation process, using the susceptibility to interference as a tool to reveal memory stabilization, given that one of the hallmarks of the memory stabilization process is the vulnerability of memory to amnesic agents, including retroactively interfering stimuli [13][14][15]. From a neurobiological perspective, if an interference task shares the same memory system than the target memory, it implies a competition for shared resources between the original and new memory [13]. So, manipulating the interval between the acquisition of the target memory and the interference task allows one to obtain a profile of the susceptibility to interferences that could hint towards the neurobiological basis of memory consolidation [7]. ...

Reference:

Non-linear susceptibility to interferences in declarative memory formation

... Further systematic laboratory studies of retrograde amnesia using ECS in rats were pioneered by Carl Duncan (1949) and generally supported Müller and Pilzecker's (1900) speculations concerning the time course of consolidation. In these experiments, temporally graded retrograde amnesia in rats for an active avoidance task was produced by ECS up to 15 mins following learning, but not at intervals longer than 1 hr. ...

Reference:

Rethinking Memory Impairments: Retrieval Failure