A. P. Kadyrkov’s scientific contributions

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Publications (2)


Fig. 1. The scheme of the experimental setup for the PMF treatment of the neutrophil suspension.
The PMF induction at different distances from the inductor
The Effect of Pulsed Magnetic Fields on the Production of Reactive Oxygen Species by Neutrophils
  • Article
  • Full-text available

July 2021

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85 Reads

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1 Citation

Biophysics

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E. V. Yablokova

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A. P. Kadyrkov

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E. E. Fesenko

It has been shown that pulsed magnetic fields (the first mode: pulse duration of 2 ms, frequency repetitions of 6.25 Hz, the pulse was bell-shaped; and the second mode: pulse duration of 1 ms, repetition frequency of 100 Hz, the pulse was bell-shaped) affected the intensity of luminol-dependent chemiluminescence of neutrophils in a wide range of pulsed magnetic fields (0.0004–10 mT). For the detection of the effects of pulsed magnetic fields by this method, it was necessary to add forbol-12-meristat-13-acetate, an activator of the production of reactive oxygen species, to the suspension of neutrophils. However, this mechanism of action of pulsed magnetic fields on the production of reactive oxygen species in neutrophils was not the only one, since lucigenin-dependent chemiluminescence also reacted to their action in a system without activators.

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