A Odone's research while affiliated with University of Pavia and other places
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Publications (81)
Adolescence is a critical period for the physical and cognitive development. To promote adolescents' health and well-being, prevention and health education interventions are to be implemented at all levels of society, with schools and families playing a fundamental role. In 2015, the "Semi di Melo" Center for Education and Research on Childhood and...
Background
The COVID-19 pandemic and associated lockdown measures posed an unprecedented challenge to the crucial role of grandparenting in family-oriented cultures, such as Italy. Reduced contact with grandchildren during this period potentially threatened grandparents’ mental health and well-being.
Methods
We analysed data from the LOckdown and...
Background
As part of continuing medical education, frontline healthcare workers (FHWs) have to maintain high standards of competence and knowledge. It is particularly true in the field of vaccination and vaccine acceptance, where knowledge and technologies evolve rapidly.
Methods
For this reason, we developed an anonymous 47-item web-based survey...
In the context of the Sars-Cov-2 pandemic, according to the various periods of emergency and the rate of infections, hospitalized subjects also contracted the infection within the ward, sometimes with the development of disease (COVID-19) and sometimes with permanent damage. The authors wondered if Sars-Cov-2 infection should be considered on a par...
The debate around vaccine mandates has flourished over the last decade, with several countries introducing or extending mandatory childhood vaccinations. In a recent study, Attwell and Hannah explore how functional and political pressures added to public health threats in selected countries, motivating governments to increase the coerciveness of th...
In the last decades, the World Health Organization has sensitized all countries to adopt a Primary Health Care approach in their health systems. It is also important to invest in education about primary health care. Indeed, we need to spread this comprehensive culture of health, starting from university education, and continuing during the whole wo...
This study aims to compare the accelerometer‐measured daily patterns of PA and sedentary behaviour among participants with and without prevalent/incident depressive symptoms. We used data from 5,582 individuals in The Maastricht Study (59.9 ± 8.6 years, 50.3% women). Daily patterns of sedentary time, light‐intensity physical activity (LiPA), modera...
Background:
School closures and distance learning have been extensively adopted to counter the COVID-19 pandemic. However, the contribution of school transmission to the spread of SARS-CoV-2 remains poorly quantified.
Methods:
We analyzed transmission patterns associated with 976 SARS-CoV-2 exposure events, involving 460 positive individuals, as...
To work efficiently in healthcare organizations and optimize resources, team members should agree with their leader’s decisions critically. However, nowadays, little evidence is available in the literature. This systematic review and meta-analysis has assessed the effectiveness of leadership interventions in improving healthcare outcomes such as pe...
During the two years of the COVID-19 pandemic, more than 400 million cases all over the world have been identified. Health care workers were among the first to deal with this virus and consequently a high incidence of infection was reported in this population. The aim of the survey was to investigate health care workers’ (HCWs) clinical characteris...
Objectives:
We compared the characteristics and outcome of vaccinated and non-vaccinated patients hospitalized for COVID-19.
Design:
Patients hospitalized in a COVID hub during three one-month periods were analysed: i) October 15th-November 15th, 2020 (pre-vaccination peak); ii) October 15th-Novembre 15th, 2021 (Delta wave); iii) December 15th,...
Aims
Restrictions imposed to prevent SARS-CoV-2 transmission should be weighed against consequences on vulnerable groups’ health. Lifestyles and disease management of older people with diabetes might have been differentially impacted compared to non-chronic individuals.
Methods
A cross-sectional study (LOST in Lombardia) was conducted on a represe...
The COVID-19 pandemic had an unfavorable impact on overall mortality in Italy, with the strongest consequences in northern Italy. Scant data are available on cause-specific mortality. This study aims at investigating the impact of the pandemic on the overall and cause-specific mortality in one province in northern Italy, Pavia. We linked individual...
Background School closures and distance learning have been extensively applied to control SARS-CoV-2 transmission. Despite evidence of viral circulation in schools, the contribution of students and of in-person schooling to the transmission remains poorly quantified. Methods We analyze 976 exposure events, involving 460 positive individuals, as ide...
In January 2020, Chinese health authorities identified a novel coronavirus strain never before isolated in humans. It quickly spread across the world, and was eventually declared a pandemic, leading to about 310 million confirmed cases and to 5,497,113 deaths (data as of 11 January 2022). Influenza viruses affect millions of people during cold seas...
Objective:
to report on the characteristics and impact of "Igiene Insieme", a school-based national-level educational programme designed and implemented in Italy to promote hygiene and sanitation in schools, stimulate healthy behaviors in teachers, students and their families, and ultimately fight COVID-19.
Methods:
the project targeted kinderga...
Background
Contact tracing (CT) is a pillar of infection control during outbreaks and its implementation has been great ally in the context of the COVID-19 pandemic that pressured national health systems. Digital CT (DCT) aids manual CT by logging proximity contacts and timely notifying contacts of positive cases, contributing to greater epidemic....
As digitalization is progressively permeating all aspects of healthcare. Here we will address how can we address the potential of applying digital tools to public health and discuss some key challenges. We have identified the strategic pillars for a successful European strategy for public health digitalization and we outlined how the approach being...
Introduction:
Several studies described burnout levels of healthcare workers (HCWs) during the COVID-19 pandemic; however, sex-related differences remain poorly investigated.
Objective:
To describe sex-related differences in burnout and its determinants among HCWs during the first pandemic wave of the COVID-19 in Italy.
Methods:
A cross-sectio...
The efficacy of hydroxychloroquine (HCQ) in treating SARS-CoV-2 infection is harshly debated, with observational and experimental studies reporting contrasting results. To clarify the role of HCQ in Covid-19 patients, we carried out a retrospective observational study of 4,396 unselected patients hospitalized for Covid-19 in Italy (February–May 202...
After SARS-CoV-2 vaccines development came at an unprecedented speed, ensuring safe and efficient mass immunization, vaccine delivery became the major public health mandate. Although mass-vaccination sites have been identified as essential to curb COVID-19, their organization and functioning is challenging. In this paper we present the planning, im...
The efficacy of hydroxychloroquine (HCQ) in treating SARS-CoV-2 infection is harshly debated, withobservational and experimental studies reporting contrasting results. To clarify the role of HCQ in Covid-19patients, we carried out a retrospective observational study of 4,396 unselected patients hospitalized for Covid-19 in Italy (February–May 2020)...
Clinical pathways represent a multidisciplinary approach to translate clinical practice guidelines into practical interventions. The literature from 2010 onward regarding the efficacy of adopting a clinical pathway on patient-related outcomes within the in-hospital setting has not been synthesized yet. For this reason, this systematic review and me...
INTRODUCTION:
Exposure to secondhand aerosol from e-cigarette (SHA) may pose harmful effects to bystanders. This study aims to investigate the prevalence, duration and determinants of SHA exposure in various indoor settings in 12 European countries.
METHODS:
In 2017-2018, we conducted a cross-sectional study, the TackSHS survey, on a representativ...
Background
Lombardy is Italy's most affluent and most populated region, with the highest national per capita GDP, and over 10 million residents - more than 16 out of 27 EU countries. In 2017, two measures were approved against vaccine hesitancy, i.e. the National Plan for Vaccine Prevention (2017-2019) and Law no. 119 on mandatory vaccinations. Aim...
Issue
National and international health authorities have described Narrative-based medicine (NBM) in clinical practice as a fundamental tool for acquiring, understanding and integrating the different points of view of those involved in the disease and its treatment, promoting more effective and appropriate care.
Description of the problem
The use...
The second and final phase of the EUVIS (EUrope Vaccines ICT Strategies) project, coordinated by the School of Public Health of the University Vita-Salute San Raffaele in Milan (Italy), aims at collecting best practices on the use and impact of Information and Communication Technologies (ICT) and digital tools to increase vaccine uptake and ultimat...
Background
In Italy on the 20th of February, the first Italian patient was tested positive for Coronavirus Disease 2019 (COVID-19) in the Lombardy region. The Regional Emergency Medical Services (EMS) Trust (Azienda Regionale Emergenza Urgenza, AREU) of the Lombardy region decided to apply a Business Intelligence (BI) System to take timely decision...
Telemedicine is the practice of medicine from distance using information technology and include mainly teleconsultation via video and/or chat, teleexpertise to request the opinion of a specialist, and remote patient monitoring to improve the follow-up of patients. The use of telemedicine in mental health and most specially psychiatry has been one o...
IRCCS San Raffaele Hospital HTA Committee
Aim
Due to the improving of life conditions, life expectancy is steadily increasing, especially in developed countries. In this perspective, Governments have to face important challenges as guaranteeing the welfare state, providing pensions and long-term healthcare for an increasing number of people. To maintain the sustainability of the pension sy...
Background
The Health in All Policies approach has been increasingly used to assess public health impact of rules and regulations. In 2015, all UN member States adopted 17 Sustainable Development Goals (SGDs) to achieve the 2030 Global Agenda. SDGs can be conceived in a practical way, as analytic tools to classify existing legislation. In the conte...
As smartphone usage is more and more ubiquitous, the app market is flourishing in all fields, including health. Indeed, the availability and use of smartphone apps (SAs) in health has exponentially grown in recent years. It has been estimated that in 2018 there were over 97,000 health apps available and that, 15% and 8% of US phone users aged 18-29...
Population ageing presents both challenges and opportunities for societies around the world. Increasing statutory retirement age and limiting exits to early retirement are frequent policy responses to population ageing, but this is unlikely to have the desired impact if the complex relationships that link work, retirement and health remains unknown...
Background
The digital transformation provides tools to empower individuals and enable feedback and interaction between users and healthcare providers. Although Personal Electronic Health Records (PEHR) have been identified as innovative tools enabling the provision of patient-centered care and prevention, evidence on their impact is scant.
Method...
Background
The clinical and surgical procedures are often based on scientifical evidence but 30-40% of patients do not receive treatment according to evidence based medicine. The main aim of this review and meta-analysis is to assess the effectiveness of leadership in healthcare setting.
Methods
It was conducted a literature research on MEDLINE, P...
Background
Previous studies suggested that social network characteristics are associated with depression. However, most of the previous studies investigated social network characteristics in isolation. We assessed the association of both structural and functional social network characteristics with prevalent and incident depressive symptoms over 5...
Background
Since the World Health Organization (WHO) declared the coronavirus infectious disease 2019 (COVID-19) outbreak a pandemic on March 11th, severe 'lockdown' measures have been adopted by the Italian Government. For over two months of stay-at-home, houses became the only place where people slept, ate, worked, practiced sports, and socialize...
Background
HIV is still a critical public health threat in Europe, especially in some at-risk populations. Stigma keeps undermining access to prevention, diagnosis, and care. Treatment as Prevention (TasP) and Pre-Exposure Prophylaxis (PrEP) have spread heterogeneously across the continent. The study aimed to compare recent HIV incidence trends in...
Background
During infectious disease emergencies, fully aware healthcare workers (HCWs) and public services staff are unique resources to keep health systems active and tackle epidemics. Aim of the study was to assess concern, general and health-related knowledge (case management and Infection Prevention and Control [IPC] measures) among hospital s...
Background
Urban world population has raised to 4.2 billion in 2018, with 2.5 billion more forecasted by 2050. Cities are places of opportunities but, at the same time, sites of environmental and social risk factors. Scientific evidence about urban green's environmental benefits is abundant, but Public Health outcomes are seldom carefully defined....
Background
Patients with type 1 (T1DM) and type 2 (T2DM) diabetes are at increased risk of vaccine-preventable diseases and their complications. The National Vaccinal Prevention Plan 2017-2019 includes specific recommendations for patients with diabetes, which in 2018 have been included in the standards of care of the Italian Diabetes Society (SID)...
Issue
With population aging, increased demand for healthcare and limited availability of economic and human resources, well-functioning and sustainable health systems have to rely on rigorous and evidence-based assessments of complex technologies' clinical effectiveness and safety. The Lombardy Region in Northern Italy has a well-established HTA pr...
Background
Even thought lifestyle changes have a main role in cardiovascular disease prevention, people show a weak adherence to medical advices. Aim of our study was to identify anamnestic predictors of poor compliance for lifestyle changes in a general population.
Methods
We submitted a 26 questions questionnaire to 301 general population subjec...
Issue
San Raffaele Hospital (OSR) is part of a European alliance of 9 University Hospitals (EUHA) which promotes comparison and excellence in the clinical, research and training strategies.
Description of the Problem
The development of Value-Based (VB) strategies has been active in OSR since March 2019, with multidisciplinary healthcare pathways a...
Background
Multidrug-resistant organisms (MDRO) are one of the most critical public health concerns, particularly in hospital settings. Nearly 8% of hospitalized patients develop healthcare-associated infections (HAI), 20% of which is caused by MDRO.
Aim of the study was to estimate nosocomial infection-associated in-hospital mortality, by differen...
Issue
Filling out medical records properly in Emergency Departments (ED) can be challenging, due to the high number of daily admissions and the variety of involved health care professionals (HCP).
Description of the Problem
The ED of IRCCS San Raffaele Hospital (OSR), with a mean of 198 admissions per day in 2019, suffers of frequent overcrowding;...
Background
Hydroxychloroquine (HCQ) was proposed as potential treatment for COVID-19.
Objective
We set-up a multicenter Italian collaboration to investigate the relationship between HCQ therapy and COVID-19 in-hospital mortality.
Methods
In a retrospective observational study, 3,451 unselected patients hospitalized in 33 clinical centers in Italy...
Background and aims
There is poor knowledge on characteristics, comorbidities and laboratory measures associated with risk for adverse outcomes and in-hospital mortality in European Countries. We aimed at identifying baseline characteristics predisposing COVID-19 patients to in-hospital death.
Methods and results
Retrospective observational study...
Objective
Information is scanty on the patterns and settings of electronic cigarette use and on its possible adverse events. To fill the knowledge gap on these issues, we conducted a survey among ever-smokers attending smoking cessation services (SCS) in Italy.
Methods
In 2016–2018, we enrolled 395 ever-smokers aged ⩾18 years who were current or f...
On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) outbreak as a pandemic, with over 720,000 cases reported in more than 203 countries as of 31 March. The response strategy included early diagnosis, patient isolation, symptomatic monitoring of contacts as well as suspected and confirmed cases, and publ...
Background:
Working age is increasing across Europe. Seasonal influenza (SID) and pneumococcal disease (PND) immunization programmes might be successfully implemented at the workplace. We conducted a cross-sectional survey among to assess SID and PND vaccine status, as well as knowledge, attitudes and practices (KAP) in a representative sample of...
Italian issues: Digital technologies in rescue services can can modify and improve the difficulties of isolated communities by bringing excellent services to the citizens living in those areas
Background
Vaccines have greatly reduced the burden of infectious diseases worldwide. The European Union has recognized immunization programs as key prevention interventions to reduce the burden and related costs of infectious diseases in Europe and has stressed the importance of adopting a life-course approach to immunization. Nonetheless, vaccine...
The Italian National Health Service (I-NHS) was established in 1978 to guarantee universal access to healthcare. Prominent in international reports, the I-NHS has reached a satisfactory level of efficiency and excellent standards of care in many regions, in forty years. Along the years, I-NHS has developed a structural public-private partnership in...
Background
Control of Healthcare associated infections (HAI) is a key public health concern in Europe. Current HAI surveillance systems are based on manual medical records review, vulnerable to misclassification & expensive. Artificial intelligence (AI), as a digital tool, offers great potential to HAI control. Still, scant evidence is available on...
We reported the case study of Professor Roberto Burioni, a medical microbiologist and virologist who, in 2015, started a personal social media campaign to contrast anti-vaccinists, using Facebook and other social media to disseminate the science behind vaccines and disseminating scientific data to refute rumors about their dangers. With over 500,00...
Background
Advances in the field of Information and Communication Technology (ICT) are revolutionizing healthcare, while massive migration flows and cross-border populations’ transit impose the planning, implementation, and evaluation of new integrated healthcare services and programmes. Nevertheless, no conclusive evidence exists on the vast poten...
Introduction
Reminder and recall interventions have been proven to be effective in increasing vaccination coverage. Emails are a popular mean of communication, and their use as a reminder method has many potential benefits: low costs, timely delivery and no restriction of content. Nevertheless, there is limited evidence that compares the advantages...
Background
Control of Healthcare associated infections (HAI) is a key public health concern in Europe. Current HAI surveillance systems are based on manual medical records review, vulnerable to misclassification and expensive. Artificial intelligence (AI) offers great potential to public health action and, specifically, to HAI control. Still, scant...
EUPHA President, and EJPH Editor Natasha Azzopardi-Muscat will present the structure and content of the European Journal of Public Health 2019 supplement on Digital Health
Background
Information and communication technology has a great potential to improve vaccine uptake by increasing the demand of vaccines and the supply of life-course immunization services. The EUVIS (EUrope Vaccines ICT Strategies) project aims at assessing the current use of ICT in European countries’ immunization programs to inform the planning...
Background:
As digitalization is progressively permeating all aspects of society, how can be it fruitfully employed to sustain the public health goals of quality, accessibility, efficiency and equity in health care and prevention? In this paper, we reflect on the potential of applying digital tools to public health and discuss some key challenges....
Background and aim:
An increase of vaccine hesitancy has spread worldwide and lead to reduction in coverage rates. The trivalent Measles-Mumps-Rubella (MMR) vaccine has been one of the most targeted leading due to possible (but never proven) adverse effects. This resulted in an increase of measles cases. The aim of the study is to analyze the 24-m...
Introduction:
In 2018 the Council of Europe adopted a Recommendation on strengthened cooperation against vaccine preventable diseases. Among EU Member States, Italy has a long-lasting tradition of immunization policies implemented in the context of the National Health Service over the last forty years.
Methods:
We identify, report and critically...
Obsessive-compulsive disorder (OCD) is one of the most difficult additional diagnoses to manage in patients with bipolar disorder (BD) since the gold standard treatment for one disease (antidepressants for OCD) can worsen the other. This case report describes the efficacy of aripiprazole augmentation as maintenance therapy in a young patient with c...
Citations
... Accelerated declines could be observed in OC mortality, from 2% per year to almost 4% per year from 2017 through 2020 2 . The agestandardized OC death rate fall 6% to 4.3/100, 000 in 2022, and it was predicted to continue doing so until 2025 at least 4,5 . These favorable patterns likely nd their main driving factor in advancements in novel therapeutic regimens 5 . ...
... In this perspective, simultaneously work on health education (among general public or, as in this case specific target populations) and HCWs' training (and re-training) is of paramount importance to concurrently and correctly inform people and ensure an updated and timely education of HCWs [82]. This dual action allows, on the one hand, facilitating the public's access to appropriate sources of information, and on the other hand, dispelling doubts among HCWs [83], especially in the case of vaccine administration among pregnant women. This is particularly important given the novelty of the vaccine and the subsequent influx of new available information [84][85][86][87]. ...
... In 2022, the Mondino Foundation's HICC established a comprehensive plan for HAI prevention. The hospital administration supported the project as a strategic area for research [40,41] and development. The four aforementioned dimensions (institutional safety and a supportive climate; continuous training and education; widespread reminders in the workplace; alcohol-based hand rub at points of care for healthcare employees) were developed at the same time the HandInScan ® scanner was introduced. ...
... China is in the "critical period", "hard period" and "window period" of ecological civilization construction, and the ecological and environmental situation is still very serious. The only way to effectively solve environmental problems and improve the efficiency of environmental governance is for all people to share the "ecological dividend" and "green welfare" [1][2][3][4]. China's environmental governance is changing from a single administrative-led model to a diversified shared governance model, which also indicates that China will build a social action system for the whole population to participate in environmental governance in the future [5]. ...
... Esta herramienta tiene el potencial de convertirse en un futuro en la principal estrategia de monitoreo de campo, registro de casos y contención de las cadenas de contagios si se consigue su uso masivo y casi diario durante brotes de alguna enfermedad epidémica nueva o ya conocida Petersen et al., 2021). Esta herramienta no ha sido realmente útil durante la pandemia de covid-19 porque los costos siguen siendo prohibitivos, pero todo indica que debería jugar un rol primordial en brotes futuros, superando a los sistemas de monitoreo de caso-contacto digitales que probaron ser sumamente costosos y muy poco efectivos (Pegollo et al., 2021;Zetterholm et al., 2021;Alo et al., 2022). ...
... In the first two years of the COVID-19 pandemic, distance learning and reactive class closures have been extensively implemented in a variety of high-income countries to counter the spread of SARS-CoV-2 (Manica et al., 2021). Large outbreaks among school-age children have been reported in different countries (Manica et al., 2022a;Stein-Zamir et al., 2020;Vardavas et al., 2022), and ad-hoc monitoring of the transmission during in-person education revealed a non-negligible proportion of secondary cases linked to school contacts (Vardavas et al., 2022;Tonon et al., 2021;Larosa et al., 2020;Meuris et al., 2021;Gamboa Moreno et al., 2021;Kremer et al., 2022;van Iersel et al., 2023;Pray et al., 2020;Peetluk et al., 2021;Macartney et al., 2020). Data from US and Sweden highlighted an increased risk of infection and COVID-19-related outcomes among people living with a child or a teacher attending school in person (Lessler et al., 2021;Vlachos et al., 2021), suggesting that SARS-CoV-2 transmission in educational settings should not be underestimated. ...
... One of society's greatest challenges is to combat sedentary lifestyles in order to prevent the onset of cardiovascular diseases and problems associated with physical inactivity [1], since physical inactivity is considered the fourth leading risk factor for mortality worldwide [2]. Research has associated low or non-existent levels of physical activity with an increased risk of developing diseases such as diabetes, cardiovascular diseases, hypertension, breast or colon cancer, as well as mental illness [3][4][5][6][7]. ...
... In the light of the above, policymakers should face the disparities and inequities in healthcare access experienced by economically poorer demographic sections and implement catch-up activities [39,40]. Efforts need to be made to promote integration between the public education system and the national health service by incorporating science classes on health education in school curricula. ...
... In this study, COVID-19 incidence was highest in two age groups, 30-40 years and 40-50 years, at 27.3 and 23.4%, respectively. The study results are consistent with the literature concerning healthcare workers [39][40][41] but different from published data on the general population [41], which may result from healthcare workers' intensive professional activity and the need to combine more social roles during the pandemic than the general population. As the study involved a group of healthcare workers that differs in sex and age structure from the general population, its results are not directly generalizable. ...
... On the other hand, effectiveness against hospitalization and mortality remained sustained even after 20 weeks from vaccination [8], and data from a large meta-regression indicated an overall preserved protection against severe COVID-19 for up to 6 months (effectiveness > 50%) [9]. Among patients admitted to intensive care unit (ICU), vaccinated were characterized by older age [10,11] and a higher number of comorbidities [10,12]. In particular, what emerged from different studies is that vaccinated patients were more often affected by chronic heart disease (CHD), diabetes mellitus (DM), chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD), and conditions which determine immunosuppression [13][14][15]. ...