A Kolesarova’s scientific contributions

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Publications (4)


Environmental Contaminants and Medicinal Plants Action on Female Reproduction
  • Book

January 2022

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14 Reads

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8 Citations

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A. Kolesarova

Environmental Contaminants and Medicinal Plants Action on Female Reproduction discusses the problem of environmental pollution, medicinal and food plants, and their impact on reproduction. The book describes the mechanisms of environmental contaminants’ action, outlines the key causes of their harmful impact on reproduction, and explores what regulatory substances and processes should be targeted due to the negative effect of pollutants on reproduction. Furthermore, it describes the provenance, properties, physiological and therapeutic effects, and possible areas of application of the known medicinal and functional food plants and their constituents with a focus on female reproductive processes. This book will be a useful resource for reproductive biologists, specialists in assisted reproduction, animal production and phytotherapy, toxicologists, pharmacologists, pharmaceutical scientists, endocrinologists, medicinal and natural product chemists, nutritionists and others engaged in the study of environmental contaminants and medicinal and functional food plants.


Puncture Vine (Tribulus Terrestris L.) in Control of Health and Reproduction

December 2021

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28 Reads

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7 Citations

Physiological research / Academia Scientiarum Bohemoslovaca

Tribulus terrestris, L. (puncture vine) have been used as a folk medicine for five thousands of years, but its targets, effects, their mechanisms and application requires further studies. This paper reviews the provenance, constituents and properties of Tribulus terrestris, L., its general physiological and health effects, as well as the currently available knowledge concerning its influence on male and female reproductive processes and their dysfunctions. Analysis of the available publications demonstrated the influence of Tribulus terrestris on a wide spectrum of targets and physiological processe and disorders. In particular, Tribulus terrestris can be a stimulator of male and female reproductive processes at the level of central nervous system, sexual behaviour, pituitary and gonadal hormones and their receptors, gonadal functions (including ovarian follicullogenesis and spermatogenesis), improvement of the quality and quantity of gametes (at least of sperm) and fecundity. This ability of puncture vine is applicable for the improvement of man’s sexual desire and sperm quality in vivo and in vitro, as well as of women’s libido, activation of women’s reproductive organs, fecundity, and treatment of infertility, especially that related to the polycystic ovarian syndrome.


Puncture vine (Tribulus Terrestris L.) in control of health and reproduction

December 2021

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51 Reads

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2 Citations

Physiological research / Academia Scientiarum Bohemoslovaca

Tribulus terrestris, L. (puncture vine) have been used as a folk medicine for five thousands of years, but its targets, effects, their mechanisms and application requires further studies. This paper reviews the provenance, constituents and properties of Tribulus terrestris, L., its general physiological and health effects, as well as the currently available knowledge concerning its influence on male and female reproductive processes and their dysfunctions. Analysis of the available publications demonstrated the influence of Tribulus terrestris on a wide spectrum of targets and physiological processe and disorders. In particular, Tribulus terrestris can be a stimulator of male and female reproductive processes at the level of central nervous system, sexual behaviour, pituitary and gonadal hormones and their receptors, gonadal functions (including ovarian follicullogenesis and spermatogenesis), improvement of the quality and quantity of gametes (at least of sperm) and fecundity. This ability of puncture vine is applicable for the improvement of man’s sexual desire and sperm quality in vivo and in vitro, as well as of women’s libido, activation of women’s reproductive organs, fecundity, and treatment of infertility, especially that related to the polycystic ovarian syndrome.


The anti-obesity and health-promoting effects of tea and coffee

April 2021

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59 Reads

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64 Citations

Physiological research / Academia Scientiarum Bohemoslovaca

This paper reviews provenance, chemical composition and properties of tea (Camelia sinensis L.) and coffee (Coffee arabica, L. and Coffea caniphora, L.), their general health effects, as well as the currently available knowledge concerning their action on fat storage, physiological mechanisms of their effects, as well as their safety and recommended dosage for treatment of obesity. Both tea and coffee possess the ability to promote health and to prevent, to mitigate and to treat numerous disorders. This ability can be partially due to presence of caffeine in both plants. Further physiological and medicinal effects could be explained by other molecules (theaflavins, catechins, their metabolites and polyphenols in tea and polyphenol chlorogenic acid in coffee). These plants and plant molecules can be efficient for prevention and treatment of numerous metabolic disorders including metabolic syndrome, cardiovascular diseases, type 2 diabetes and obesity. Both plants and their constituents can reduce fat storage through suppression of adipocyte functions, and support of gut microbiota. In addition, tea can prevent obesity via reduction of appetite, food consumption and food absorption in gastrointestinal system and through the changes in fat metabolism.

Citations (4)


... The application of plant molecules as safe regulators of physiological processes and as medicines remains popular. Several medicinal plants and plant polyphenols [1], including the flavonoid quercetin [2], can be used to prevent and functions of healthy [13,14] and cancerous [15,16] human ovarian cells. ...

Reference:

Interplay Between the MicroRNA miR-152 and Quercetin in the Control of Ovarian Granulosa Cell Functions
Environmental Contaminants and Medicinal Plants Action on Female Reproduction
  • Citing Book
  • January 2022

... Based on TCM theory, Tribulus terrestris L. (TT), a common herb and first documented in Shen-Nong-Ben-Cao-Jing, is able to calm liver and dispel melancholy ("Ping Gan Jie Yu in Chinese), promote blood circulation to dissipate wind ("Huo Xue Qu Feng" in Chinese), improve eyesight ("Ming Mu" in Chinese) and relieve itching ("Zhi Yang" in Chinese). Previous studies demonstrated the effects of TT on prostate health [8], reproductive processes [9], hypertensive renal injury [10], inflammation, ovarian cells apoptosis and so on [11]. But the study on anti-liver cancer of TT was hardly reported. ...

Puncture Vine (Tribulus Terrestris L.) in Control of Health and Reproduction
  • Citing Article
  • December 2021

Physiological research / Academia Scientiarum Bohemoslovaca

... These chemicals are thought to be physiologically active and are used in traditional communities for their medicinal properties. Mechanisms of action are not well understood, and may be mediated by changes in hormones, cytokines, and growth factors release, binding and action [61]. It may induce relaxation of the corpus cavernosum and therefore improve erectile function. ...

Puncture vine (Tribulus Terrestris L.) in control of health and reproduction
  • Citing Article
  • December 2021

Physiological research / Academia Scientiarum Bohemoslovaca

... Senyawa ini memberikan efek antioksidan, antiinflamasi, dan metabolik yang berkontribusi terhadap pencegahan dan pengelolaan berbagai kondisi kesehatan, seperti obesitas, diabetes, penyakit kardiovaskular, dan gangguan metabolik lainnya. Dengan berbagai keunggulan ini, kopi tidak hanya menjadi bagian dari gaya hidup, tetapi juga elemen penting yang mendukung kesehatan fisik dan mental di tengah masyarakat modern (Sirotkin & Kolesarova, 2021). ...

The anti-obesity and health-promoting effects of tea and coffee
  • Citing Article
  • April 2021

Physiological research / Academia Scientiarum Bohemoslovaca