A. Jemal's research while affiliated with American Cancer Society and other places

... Further, to capture the extra variation, models were developed incorporating linear and quadratic behavior of the process. Both models are generally expressed as semi-parametric Bayesian versions of local linear and local quadratic state-space models [13,14]. The application and limitation of mixed effect are explained for the analysis of longitudinal dynamic system [15]. ...

... Emerging evidence also identified abnormal HBV DNA copies in several extrahepatic tissues, including the stomach, pancreas, and colorectum, which indicated the potential association between HBV infection and extrahepatic cancer risk (5,6). An epidemiological report evaluating the cancer deaths and cases in China attributable to lifestyle factors and infections revealed that HBV infection accounted for 12% and 7% of cancer-associated mortality in men and women, respectively (7). Recent large-scale population-based studies and meta-analyses have detailed these under-estimated connections (8)(9)(10)(11)(12). ...

... In the Western Hemisphere, colorectal cancer is the most common cancer, and its incidence rises with age. Therefore, confirming associations between circRNAs and colorectal cancer is important [67]. CircRNA circ-FBXW7 overexpression significantly suppresses colorectal cancer proliferation, migration and invasion [68]. ...

... In clinical settings, a variety of medical and surgical techniques have been used, with over 50 percent of HCC patients displaying an unresectable or un-embolized state. Because of vascular invasion or extrahepatic metastases' limits, there are only palliative therapies accessible [3][4][5][6]. Sorafenib stimulates apoptosis by reducing tumor angiogenesis and growth. Restriction of VEGFR2-PDGFR-and Raf-kinase characteristics, signaling pathways found as a close reason in HCC research and offering survival advantages in advanced HCC, is how anti-angiogenic activity is achieved Patients receiving sorafenib have constraints in clinical settings, such as expensive costs that put a strain on finances, significant side effects (28-89%) that might restrict sorafenib intake and hamper treatment approaches, and a high rate of tumor progression with a single drug [7][8][9][10][11][12][13][14]. ...

... MiR-34 stands out as a critical mediator. Numerous reports have confirmed that the expression of miR-34a can prevent proliferation, migration, invasion, metastasis, and the epithelialto-mesenchymal transition of cancer cells (Bader et al. 2010) (Jemal et al. 2011). ...

... Cancer is the leading cause of death among Hispanics. However, only 1.3% of eligible Hispanic cancer patients participate in cancer-related clinical trials [32,33]. Patient education on clinical trials and materials in Spanish can improve their enrollment [34]. ...

... In addition, although smoking is the primary cause of lung cancer, roughly 25% of patients worldwide do not currently smoke, and patients with lung cancer who have never smoked have the seventhhighest mortality rate of all cancer patients worldwide. 48 According to Sui et al., 49 miR-34a tends to be overexpressed in lung cancer patients who never smoked and may therefore contribute to the development of this disease. ...

... Nearly 300,000 people die of HNSCC each year. 1 Over 63,000 new cases of HNSCC were reported in the United Stated per year, accounting for 3.6% of all sites. 2 Due to radical ablation of lesions, survivors suffered severe pain, changed voice, unfavorable swallowing, decreased social activities, and a lower quality of life. 3 It is urgent to further explore the etiological mechanism of HNSCC and provide novel treatment targets. ...

... Colorectal cancer is the fifth most commonly diagnosed cancer and the fifth leading cause of cancerrelated mortality in China [1]. The standard of care for patients with locally advanced rectal cancer (LARC) is neoadjuvant concurrent chemoradiotherapy (nCCRT), typically followed by total mesorectal excision [2]. ...

... Transhiatal oesophagectomy with intrathoracic gastric placement together with cervical anastomosis is a procedure with less surgical trauma and fewer respiratory complications. 1 The overall risk for men and women is 0.8% and 0.3% respectively. 2 As the age increases the lifetime risk also increases. ...