T. K. Konse

Indiana University Bloomington, Bloomington, Indiana, United States

Are you T. K. Konse?

Claim your profile

Publications (1)5.64 Total impact

  • AH Que · T. K. Konse · AG Baker · Milos V. Novotny
    [Show abstract] [Hide abstract]
    ABSTRACT: Different macroporous, monolithic capillary columns were prepared to separate various bile acid mixtures through capillary electrochromatography (CEC) at high efficiency. These columns are shown to be ideally suitable for coupling to an electrospray ionization/ion trap mass spectrometer. Detection and structural identification of different bile acid derivatives in either the positive- or negative-ion mode necessitated column technologies with different polarities and the capabilities of a reversed electroosmotic flow. High column efficiencies (610,000 theoretical plates/meter for glycocholic acid in normal-phase separation) were preserved in the coupling to mass spectrometry (MS), with the detection limits of approximately 40 femtomole (for cholic acid) and identification through CEC/MS/MS.
    No preview · Article · Aug 2000 · Analytical Chemistry

Publication Stats

87 Citations
5.64 Total Impact Points

Top Journals


  • 2000
    • Indiana University Bloomington
      • Department of Chemistry
      Bloomington, Indiana, United States