[Show abstract][Hide abstract] ABSTRACT: The objective of our study was to determine the prevalence of honorary authorship in articles published in the American Journal of Roentgenology (AJR) and to evaluate the factors that might influence the perception of honorary authorship.
Corresponding authors of 1333 Original Research articles published in AJR between 2003 and 2010 were invited by e-mail to complete a Web-based, self-administered survey. Univariable analysis of sample proportions was performed using the chi-square test. Multivariable logistic regression models were used to assess the independent factors that were associated with the probability of honorary authorship.
Responses were received from authors of 490 articles (36.8% response rate). Most respondents were aware of the authorship guidelines proposed by the International Committee of Medical Journal Editors (n = 399, 81.4%) and the issue of honorary authorship (n = 353, 72.0%). Authorship was most commonly decided by the first author (n = 256, 52.2%). One hundred twenty-one authors (24.7%) perceived that one or more coauthors listed for the respective article did not make sufficient contributions. Factors most strongly associated with honorary authorship included a work environment where a senior department member was automatically listed (odds ratio [OR], 1.33), the suggestion that an honorary author should be included (OR, 5.96), and the perception that a coauthor performed only a single nonauthor task (i.e., reviewing the manuscript: OR, 1.54).
A substantial proportion of articles had evidence of honorary authorship. The rate of honorary authors was higher among authors who worked in an environment where senior members were routinely added to all manuscripts submitted for publication, authors who perceived that a coauthor listed had only reviewed the manuscript, and authors who reported that someone suggested they should include an honorary author.
Full-text · Article · Jun 2012 · American Journal of Roentgenology
[Show abstract][Hide abstract] ABSTRACT: To evaluate volumetric changes in apparent diffusion coefficient (ADC) and contrast material enhancement on contrast-enhanced (CE) magnetic resonance (MR) images in hepatic arterial and portal venous phases for assessing early response in cholangiocarcinoma treated with transcatheter arterial chemoembolization (TACE).
Twenty-nine patients with unresectable cholangiocarcinoma, including 11 men (mean age, 60 years; standard deviation, 16.8) and 18 women (mean age, 63 years; standard deviation, 11.5) were included in this retrospective institutional review board-approved, HIPAA-compliant study; informed consent was waived. Sixty-nine TACE procedures were performed during the observational time (range, one to five TACE sessions). No patients received another form of therapy after treatment with TACE. MR Imaging was performed before and 3-4 weeks after TACE, and images were analyzed with a semiautomatic volumetric software package. Patients were stratified as responders and nonresponders on the basis of overall survival (OS) as the primary end point. Differences between responders and nonresponders were analyzed with paired t tests, and OS was calculated with the Kaplan-Meier method. Significant differences were analyzed with the log-rank test.
Mean volumetric ADC increased from 1.54×10(-3) mm2/sec to 1.92×10(-3) mm2/sec (P<.0001), with no significant decrease in mean volumetric enhancement in hepatic arterial (40.6% vs 37.5%, P=.546) and portal venous (79.0% vs 70.0%, P=.105) phases. Patients who demonstrated improved survival of 10 months or more had a significant increase in mean volumetric ADC and volumetric ADC above the threshold level of 1.60×10(-3) mm2/sec (P<.002). Patients with 45% or greater (n=21; log-rank test, P<.02) and 60% or greater (n=12; log-rank test, P<.009) ADC changes for the whole tumor volume demonstrated better OS compared with patients in whom these ADC changes were not achieved.
Patients with percentage tumor volume increase in ADC of 45% or greater and 60% or greater above the threshold level of 1.60×10(-3) mm2/sec had favorable response to therapy and improved survival.