Yaprak Engin-Üstün

Dr. Zekai Tahir Burak Women's Health Research and Education Hospital, Engüri, Ankara, Turkey

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Publications (21)12.45 Total impact

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    ABSTRACT: Objective: Obstetric cholestasis is a cholestatic disease usually commencing in the third trimester of pregnancy and characterized by pruritus, elevation of liver enzymes, and increase in bile acids. The objective of this study was to compare the first trimester serum indicators of obstetric cholestasis with normal pregnancies. Materials and Methods: Thirty-five patients diagnosed with obstetric cholestasisin a three-year period with first trimester biochemical assessment available were included in the study. Seventy patients with concordant pregnancy weeks, matched-age normal pregnancies were included as the control group. Pregnancy-associated plasma protein A (PAPP-A) and free beta-human chorionic gonadotropin (beta-hCG) levels were analyzed. Results: No difference was observed between the two groups in terms of age and week of pregnancy. While the mean PAPP-A level was 0.76 ± 0.31 multiples of the medians(MoM) in the obstetric cholestasis group, it was determined to be 1.5 ± 0.84 in the control group (p = 0.0001). Among the two groups, the hCG levels were found to be higher in the obstetric cholestasis group (1.2 ± 0.79 MoM vs. 0.98 ± 0.53, p = 0.041). Conclusion: In this study, the first trimester PAPP-A levels in the obstetric cholestasis cases were found to be significantly lower than the control group. Low PAPP-A levels should be a warning for obstetric cholestasis.
    No preview · Article · Sep 2015 · Clinical and experimental obstetrics & gynecology
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    ABSTRACT: Objective: Single umbilical artery (SUA) is the most common umbilical cord abnormality. The aim of the study was to evaluate maternal and neonatal outcomes in pregnancies with single umbilical artery. Methods: This was a retrospective study from a tertiary referral center. In this retrospective cohort study, maternal and neonatal outcomes of patients who had a diagnosis of single umbilical artery without an established anomaly were reviewed. Maternal age, gestational age at delivery, birth weight, mode of delivery, fetal gender and any complications were recorded. Results: There were 42 cases of SUA without an antenatally diagnosed established anomaly. Gestational age ranged between 258-289 days. Median maternal age was 28 (19-36) years. Gravida was 2 (1-4). There were five in vitro fertilization pregnancies, and two pregnancies with premature rupture of membranes. Two of the neonates with single umbilical artery had cryptorchidism and one had hypothyroidism. Male gender was 50%. Conclusion: When the single umbilical artery is an isolated ultrasonography finding, neonates will still have a possibility of having minor problems such as cryptorchidism.
    Full-text · Article · Jun 2015 · Mitteilungen Klosterneuburg
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    ABSTRACT: Our aim was to investigate the first trimester serum markers and nuchal translucency (NT) measurements in twin pregnancies in our population. We reviewed the results of all double tests that were performed in our hospital over a three-year period. Out of them, we selected all twins and compared them with a group of three times as many singleton controls. NT measurements and the first trimester serum markers from 49 twin pregnancies were compared to those of 147 pregnant women with normal singleton pregnancy There were no statistically significant differences in age, gestational age and maternal weight between the two groups (p > 0.05). We found similar NT measurements in the two groups. The median MoM of Pregnancy-Associated Plasma Protein A (PAPP-A) and fβ-hCG levels in twins were statistically significantly higher than those in singleton pregnancies. Twelve percent of the twins (12.2%) were the result of assisted reproduction technologies. IVF versus naturally conceived pregnancies showed similar MoM of PAPP-A (2.2 vs. 1.2, respectively) and fβ-hCG (Mann-Whitney U; p = 0.195 and p = 0.958). Our study revealed that median PAPP-A and fβ-hCG levels for twins were less than twice those of singleton values.
    Full-text · Article · May 2015 · Ginekologia polska
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    Barış Büke · Hasan Onur Topçu · Yaprak Engin-Üstün · Nuri Danışman
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    ABSTRACT: Objective: The aim of this study was to compare serum maternal adiponectin concentrations in pregnant women with isolated intrauterine growth retardation (IUGR) and in pregnant women with IUGR concomitant with pre-eclampsia (IUGRcwPE). Material and methods: Thirty patients with isolated IUGR (group 1), 20 patients with IUGRcwPE (group 2), and 30 healthy controls (group 3) between age 18-40 were included into the study. Venous blood samples of those patients were obtained in the starving state. Adiponectin concentrations were measured by enzyme-linked immunosorbent assay in serum obtained after centrifugation. To find the differences between the groups, student t-test and one-way ANOVA statistical methods were used. Results: There were no differences between the groups in terms of age, body mass index, gestational age, and parity (p>0.05). The values of amniotic fluid index (p<0.001) and weight gained during pregnancy (p=0.017) were significantly different when compared among the three groups. The mean concentrations of adiponectin were 94.041 pg/mL in the IUGR group, 55.717 pg/mL in the IUGRcwPE group, and 51.831 pg/mL in the control group. Both of the differences between the IUGR and IUGRcwPE groups (p value; <0.05) and IUGR and control groups were statistically significant (p value; <0.001). However, there were no significant differences between the IUGRcwPE group and control group (p>0.05). Conclusion: We found that IUGR increased maternal serum adiponectin concentrations; however, this rise does not occur in pregnant women with IUGRcwPE.
    Full-text · Article · Sep 2014 · Journal of the Turkish German Gynecology Association
  • Sebnem Ozyer · Yaprak Engin-Üstün · Ozlem Uzunlar · Ceren Katar · Nuri Danışman
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    ABSTRACT: Background/aims: Although the association between inflammation and insulin resistance is well known, the data related to the role of inflammation in gestational diabetes mellitus (GDM) are conflicting. The aim of this study was to investigate the association of several inflammatory mediators with the glycemic status in pregnancy. Methods: Leukocyte count, ferritin, C-reactive protein (CRP), fibrinogen and interleukin-6 levels were measured in 70 patients with normal glucose tolerance, in 57 patients with impaired glucose tolerance and in 35 patients with GDM as determined based on 50-gram oral glucose tolerance test (OGTT) and 100-gram OGTT results. Results: A significant difference among the groups was seen only with regard to CRP and fibrinogen levels; however, no significant differences were observed after adjustment for body mass index (BMI). CRP was found to be strongly associated with current BMI in all three groups. Conclusion: Maternal serum levels of inflammatory mediators are not related to GDM at the time of the glucose challenge test in the late second or early third trimester. The significant difference in the levels of CRP in different strata of glycemic tolerance was not observed after adjustment for BMI. Adiposity may have a central role in GDM, causing an inflammatory response.
    No preview · Article · May 2014 · Gynecologic and Obstetric Investigation
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    ABSTRACT: High sensitive C-reactive protein (hs-CRP) is a serum marker for acute inflammation and/or infection. The diagnostic value of serum levels of this protein has been investigated among patients with preterm delivery, premature rupture of the membranes (PROM) and preeclampsia. In this study, the predictive value of hs-CRP for successful labour induction in patients with PROM has been evaluated. Eighty-six term pregnant patients who experienced pre-labour amniotic membrane rupture from 37-41 weeks of gestation were selected for the study. Maternal serum hs-CRP levels were determined upon admission to the delivery unit and low dose intravenous oxytocin infusion was started to induce labour. The mode of delivery and time interval from labour induction to delivery were the primary endpoints of the study. Twenty-five (29%) out of 86 patients had delivered by caesarean section, while the remaining 61 (71%) had delivered vaginally. The receiver operator characteristic (ROC) curve for testing the significance of higher hs-CRP values and lower probability of vaginal delivery revealed that higher hs-CRP values were found to be insignificant for predicting the need for caesarean section. No statistically significant correlation between high serum hs-CRP levels and the probability of caesarean delivery has been established (Spearman rho:-.126; p=0.24). The mean maternal serum hs-CRP levels during PROM were found to be similar between vaginal and abdominal deliveries. Hs-CRP, as an inflammatory marker, was found to be neither specific nor sensitive for the prediction of successful labour induction in term pregnancies with pre-labour rupture of the membranes.
    Preview · Article · Mar 2014 · Journal of the Turkish German Gynecology Association
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    SALIM ERKAYA · YAPRAK ENGIN-ÜSTÜN · Ayla AKTULAY
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    ABSTRACT: Objective: C-reactive protein (CRP), a marker of systemic inflammation, increases rapidly in ischemia or traumatic injury. Ferritin, an acute phase reactant, has been found to be elevated in many chronic inflammation-related diseases. The aim of the present prospective study was to investigate and compare serum CRP and ferritin levels after vaginal birth and cesarean section. Methods: One hundred sixty pregnant women who gave birth in our hospital were included in the study. Vaginal birth (n=80) and cesarean section (n=80) groups were matched for age and gestational age. In all subjects, CRP and plasma levels of ferritin were determined. Results: Maternal age, gestational age and body mass index were not significantly different between the groups. Ferritin levels were similar in vaginal birth and cesarean section subjects. There were also no significant differences in serum concentrations of CRP between the two groups. Serum CRP was 5.8 ± 3.7 mg/L in vaginal birth group and 7.0 ± 6.8 mg/L in cesarean section group (p=0.190). Conclusion: In conclusion, our findings reveal that mode of delivery has no effect on the acute-phase proteins namely, ferritin and CRP.
    Full-text · Article · Mar 2014 · Acta Medica Mediterranea
  • SALIM ERKAYA · YAPRAK ENGIN-ÜSTÜN · AYLAAKTULAY
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    ABSTRACT: Objective: C-reactive protein (CRP), a marker of systemic inflammation, increases rapidly in ischemia or traumatic injury. Ferritin, an acute phase reactant, has been found to be elevated in many chronic inflammation-related diseases. The aim of the present prospective study was to investigate and compare serum CRP and ferritin levels after vaginal birth and cesarean section. Methods: One hundred sixty pregnant women who gave birth in our hospital were included in the study. Vaginal birth (n=80) and cesarean section (n=80) groups were matched for age and gestational age. In all subjects, CRP and plasma levels of ferritin were determined. Results: Maternal age, gestational age and body mass index were not significantly different between the groups. Ferritin levels were similar in vaginal birth and cesarean section subjects. There were also no significant differences in serum concentrations of CRP between the two groups. Serum CRP was 5.8 ± 3.7 mg/L in vaginal birth group and 7.0 ± 6.8 mg/L in cesarean section group (p=0.190). Conclusion: In conclusion, our findings reveal that mode of delivery has no effect on the acute-phase proteins namely, ferritin and CRP.
    No preview · Article · Mar 2014 · Acta Medica Mediterranea
  • SALIM ERKAYA · YAPRAK ENGIN-ÜSTÜN · AYLAAKTULAY
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    ABSTRACT: Objective: C-reactive protein (CRP), a marker of systemic inflammation, increases rapidly in ischemia or traumatic injury. Ferritin, an acute phase reactant, has been found to be elevated in many chronic inflammation-related diseases. The aim of the present prospective study was to investigate and compare serum CRP and ferritin levels after vaginal birth and cesarean section. Methods: One hundred sixty pregnant women who gave birth in our hospital were included in the study. Vaginal birth (n=80) and cesarean section (n=80) groups were matched for age and gestational age. In all subjects, CRP and plasma levels of ferritin were determined. Results: Maternal age, gestational age and body mass index were not significantly different between the groups. Ferritin levels were similar in vaginal birth and cesarean section subjects. There were also no significant differences in serum concentrations of CRP between the two groups. Serum CRP was 5.8 ± 3.7 mg/L in vaginal birth group and 7.0 ± 6.8 mg/L in cesarean section group (p=0.190). Conclusion: In conclusion, our findings reveal that mode of delivery has no effect on the acute-phase proteins namely, ferritin and CRP.
    No preview · Article · Mar 2014 · Acta Medica Mediterranea
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    ABSTRACT: Reactive oxygen species (ROS) are produced in many metabolic and physiologic processes. Antioxidative mechanisms remove these harmful species. Our aim was to assess whether serum total antioxidant capacity and total oxidant status altered during first trimester pregnancies with vaginal bleeding. In this cross-sectional study, A group of pregnant women at less than 10 weeks of gestation with vaginal bleeding (n=25) and a control group of healthy pregnancies with similar characteristics (n=25) were included. All of the patients in the two groups were matched for age, gestational age and body mass index. Serum total antioxidant capacity and total oxidant status levels were determined using a Hitachi 912 analyzer and compared between the two groups. Characteristics, including maternal age, parity, and gestational age were similar between the two groups. Serum total antioxidant capacity levels were significantly lower in the women with vaginal bleeding than in control women (1.16 ± 0.20 vs. 1.77 ± 0.08 mmol Trolox Equiv./L; p=0.001), whereas higher total oxidant status measurements were found in women with vaginal bleeding compared to the control group (4.01 ± 0.20 vs. 2.57 ± 0.65 µmol H2O2 Equiv./L; p=0.001). Increased total oxidant status might be involved in the pathophysiology of vaginal bleeding during early first trimester pregnancies.
    Full-text · Article · Feb 2014 · International journal of fertility & sterility
  • SALIM ERKAYA · YAPRAK ENGIN-ÜSTÜN · AYLAAKTULAY
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    ABSTRACT: Objective: C-reactive protein (CRP), a marker of systemic inflammation, increases rapidly in ischemia or traumatic injury. Ferritin, an acute phase reactant, has been found to be elevated in many chronic inflammation-related diseases. The aim of the present prospective study was to investigate and compare serum CRP and ferritin levels after vaginal birth and cesarean section. Methods: One hundred sixty pregnant women who gave birth in our hospital were included in the study. Vaginal birth (n=80) and cesarean section (n=80) groups were matched for age and gestational age. In all subjects, CRP and plasma levels of ferritin were determined. Results: Maternal age, gestational age and body mass index were not significantly different between the groups. Ferritin levels were similar in vaginal birth and cesarean section subjects. There were also no significant differences in serum concentrations of CRP between the two groups. Serum CRP was 5.8 ± 3.7 mg/L in vaginal birth group and 7.0 ± 6.8 mg/L in cesarean section group (p=0.190). Conclusion: In conclusion, our findings reveal that mode of delivery has no effect on the acute-phase proteins namely, ferritin and CRP.
    No preview · Article · Jan 2014 · Acta Medica Mediterranea
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    ABSTRACT: To investigate effect of the afterloaded external guidance embryo transfer technique on pregnancy rates in single embryo transfer intracytoplasmic sperm injection (ICSI) cycles. This retrospective study was performed at the Dr. Zekai Tahir Burak Women's Health Research and Education Hospital. Three hundred and thirteen women who underwent ICSI were included in the study. Subjects were categorized according to the embryo transfer technique; Group 1 (n: 232): easy transfer with a soft catheter, Group 2 (n: 45): after external guidance transfer, and Group 3 (n: 36): difficult transfer with a stylet. Basal parameters, clinical and laboratory IVF outcomes and pregnancy rates were studied. Infertility etiology, basal follicle stimulating hormone (FSH) levels, antral follicle count, duration of stimulation, total dose of gonadotropin, peak estradiol levels, endometrial thickness, oocyte number, 2 PN, and fertilization rate were similar between the three groups (p>0.05). Despite the decreased pregnancy rate in Group 3, there were no differences in clinical pregnancy rates among the groups (p=0.204). Embryo transfer is one of the critical steps in assisted reproduction procedures. Using the afterloaded external guidance embryo transfer technique did not improve pregnancy rates.
    Full-text · Article · Sep 2013 · Journal of the Turkish German Gynecology Association
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    ABSTRACT: Our aim was to investigate whether the maternal serum concentrations of first and second trimester serum analytes are altered in familial Mediterranean fever (FMF) pregnancies. The screening tests were compared in a series of 16 serum samples from FMF pregnancies and in a cohort of 48 pregnant women with normal pregnancy. Serum samples were obtained between 11 and 13 weeks; 16 and 18 weeks gestation. Serum pregnancy-associated plasma protein-A (PAPP-A) levels, expressed as multiples of the median (0.9 ± 0.45 MoM) in the control group, were significantly higher than FMF patients (0.6 ± 0.3 MoM) (p = 0.027). Analyses of alpha-fetoprotein, human chorionic gonadotropin and oestriol levels showed no significant differences between FMF and normal pregnancies. Our study revealed that low levels of PAPP-A are associated with FMF.
    No preview · Article · Jul 2013 · European review for medical and pharmacological sciences
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    ABSTRACT: Abstract We evaluated the effect of mandatory single embryo transfer (SET) on live birth rates and pregnancy outcomes in Turkey. A retrospective study was conducted in Zekai Tahir Burak Women's Health Education and Research Hospital. Four hundred and four patients undergoing intracytoplasmic sperm injection (ICSI) cycles were included in the study. In Turkey, the number of embryos to be transferred in an assisted cycle was limited to three under normal circumstances until 6 March 2010. After that, new legislation was introduced to promote the application of SET. Outcomes were compared in periods of 1 year before and after the new law. We compared pregnancy outcomes of all assisted reproductive cycles in SET cycles (group 1: n = 281) with double embryo transfer (DET) cycles (group 2: n = 123). There were significant differences in oocyte number, multiple pregnancy, gestational age, birth weight and perinatal fetal morbidity between the groups (p = 0.023, 0.001, 0.001, 0.001, 0.001, respectively). But there were no differences in age, baseline FSH, infertility period, stimulation protocol, stimulation day, gonadotrophin dose, clinical pregnancy rate, abortion rate, live birth rate and cesarean rate (p > 0.05). These results suggest that under the new legislation multiple pregnancy rates and perinatal complications are significantly reduced without causing a significant decline in the pregnancy rates.
    Full-text · Article · Jun 2013 · Gynecological Endocrinology
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    ABSTRACT: Objectives: Gestational diabetes mellitus (GDM) is defined as glucose intolerance, first time detected in pregnancy. Diagnostic criteria for GDM have changed over the decades. The aim of the study was to examine the effect of diet on birth weight, number of large for gestational age (LGA) (birth weight > 90th percentile) babies, total maternal weight gain, gestational age and route of delivery among patients with positive 50 g glucose challenge test (GCT) and negative 100 g oral glucose tolerance test (OGTT). Patients and methods: A prospective randomized controlled study was conducted among patients with positive 50 g GCT and negative 100 g OGTT. A plasma glucose value of 140 mg/dL was used as the threshold to define an abnormal GCT result. In group 1 50 patients were given a caloric diet and compared with group 2 with 50 patients without a given diet. Patients were followed up until delivery and evaluated for birth weight, number of LGA babies, total maternal weight gain, gestational age and route of delivery. Results: There were no significant differences between the groups in maternal age, parity, body mass index and gestational age at delivery. There were significant differences in birth weight, number of LGA babies, total maternal weight gain during pregnancy. The mean gestational age at delivery was 38.7±1.2 weeks in group 1 and 38.9±1.1 weeks in group 2 (p = 0.615). The mean birth weight in group 1 was 3328±399 g and 3623±485 g in group 2 (p = 0.007), cesarean rate was 32% in group 1 and 40% in group 2 (p = 0.405). Conclusions: In the management of patients with positive 50 g GCT and negative 100 g OGTT, patients who were prescribed medical nutrition therapy by a dietitian experienced in GDM management had better perinatal outcomes.
    No preview · Article · May 2013 · European review for medical and pharmacological sciences
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    ABSTRACT: The purpose of this study is to compare the effects of tubal sterilization on the ovarian reserve by means of hormonal and ultrasonographic evaluation during a cesarean section or when performed as a planned interval procedure. Fifty women who had undergone tubal sterilization during a cesarean section (n=24) and by minilaparotomy as an elective procedure (n=26) were included in the study. Tubes were ligated with the Pomeroy technique in both groups. The women who had chosen to use barrier method or intrauterine device for contraception (n=30) constituted the control group. Among the women in the control group, two separate control groups were constituted (control 1 and control 2) who were age matched with the women in each study group. Hormone levels including antimüllerian hormone (AMH) and inhibin B and ultrasonographic evaluations were performed on the third day of the menstrual cycle 1 year after the tubal sterilization procedure. Mean blood estradiol, follicle stimulating hormone and luteinizing hormone levels on the third day of the cycle postoperative 12 months after the surgical intervention did not show any significant differences in the groups with respect to their age-matched controls. There was no significant difference in terms of mean serum AMH and inhibin B levels between the groups and their age-matched controls. However, significantly higher postoperative levels of mean AMH levels were detected in the tubal sterilization during cesarean section group when compared with the minilaparotomy group, and significantly lower postoperative levels of mean inhibin B were detected in the elective tubal sterilization via minilaparotomy group when compared with the cesarean section group. Statistically significant differences were observed in terms of number of antral follicles and mean ovarian volumes being less in the elective tubal sterilization via minilaparotomy group when compared with age-matched controls. Intraoperative cesarean section tubal sterilization seems to be a practical and safe method, and has less effect on the ovarian reserve when compared with planned tubal sterilization by minilaparotomy.
    No preview · Article · Apr 2012 · Contraception
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    ABSTRACT: Our primary aim was to investigate whether N-terminal pro-brain natriuretic peptide (NT-proBNP) increases in adolescent with polycystic ovary syndrome (PCOS) compared with healthy controls and secondary aim was to determine whether metabolic and hormonal differences exist between groups. In this cross-sectional study, 25 adolescent patients with PCOS and 25 normal ovulatory control not suffering from PCOS were involved in the study. Fasting serum NT-proBNP, C-reactive protein (CRP), homocystein, insulin levels and biochemical and hormonal parameters were measured. Serum NT-proBNP was not significantly different in PCOS subjects (0.62 ± 0.80 vs 1.12 ± 1.51 ng/mL, p = 0.154). The mean serum fasting insulin levels (22.64 ± 10.51 vs 13.32 ± 3.97 mIU/mL, p = 0.001) and Homeostasis Model Assessment Insulin-Resistance Index (HOMA-IR) levels (5.16 ± 1.81 vs 2.97 ± 0.89, p = 0.001) were significantly high in the study group. The median serum CRP levels were not significantly different between groups (1 [1-12] vs 1 [1-19] g/dL, p = 0.286). The present study demonstrated that the levels of BNP, CRP and homocystein were not different in PCOS subjects. Serum insulin levels and HOMA-IR were significantly higher in PCOS subjects. Possible serum markers for PCOS-related metabolic abnormalities and cardiovascular events, may not present in the adolescent years.
    No preview · Article · Feb 2012 · Gynecological Endocrinology
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    ABSTRACT: To evaluate the asymmetric dimethylarginine (ADMA) and nitric oxide (NO) levels in obese and lean patients with polycystic ovarian syndrome (PCOS) and find out their relation with hormonal and metabolic parameters. Twenty-two obese, 18 lean patients with PCOS and 11 obese, 24 lean healthy control patients were enrolled prospectively. Plasma ADMA and NO levels and arginine/ADMA ratio were evaluated on 3rd day of menstrual cycle after at least 10 h overnight fasting. Plasma ADMA, NO levels and arginine/ADMA ratio were similar in the groups. ADMA level did not correlate with the hormonal and metabolic parameters in patients with PCOS. However, NO correlated inversely with fasting insulin (r =  -0.353, p = 0.041) and homeostasis model of insulin resistance (HOMA-IR) (r =  -0.379, p = 0.027). Arginine/ADMA ratio also correlated inversely with fasting insulin (r =  -0.339, p = 0.050). In multinomial regression analysis the risk of low NO was associated independently with high fasting insulin (OR = 1.19, 95% CI 1.001-1.42, p = 0.049) and high HOMA-IR in patients with PCOS (OR = 2.26, 95% CI 1.03-4.98, p = 0.042). Insulin resistance may be the underlying mechanism of endothelial dysfunction through NO pathway in PCOS.
    No preview · Article · Sep 2011 · Gynecological Endocrinology
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    ABSTRACT: AIM: To evaluate cases of neural tube defects detected at or referred to Inonu University Faculty of Medicine Gynecology and Obstetrics Department between 2004 and 2006. DESING STUDY: In this study, cases of neural tube defects detected at or referred to Inonu University Faculty of Medicine Gynecology and Obstetrics Department between 2004 and 2006 were evaluated. Cases were identified by a definitive prenatal radiology report. FINDINGS: There were 14 cases with spina bifida, 13 with anencepaly, 8 with spina bifida and hydrocephaly, 9 with spina bifida and acrani. Nine cases were primarily diagnosed and treated in our hospital whereas 35 were referred from other hospitals. During the study period, 3877 deliveries were performed in our clinic. When referrals from other hospitals were excluded, the incidence of neural tube defect was calculated as 2.3 per 1000 deliveries. Mean maternal age was 27.5±5.1 years and body mass index was 25.9±3.6 kg /m 2. Median gestational age at the time of diagnosis was 23 (13-41) weeks, gravida was 2 (1-9) and parity was 1 (0-6). Thirty four percent of cases were diagnosed in the third trimester and 63.6 % of cases were not under routine control. None of the patients used folic acid before of during the pregnancy. CONCLUSION: Folic acid supplementation and antenatal screening is mandatory for all pregnancies.
    No preview · Article · Jan 2007
  • Y. Üstün · Y. Engin-Üstün · M. Meydanli · R. Atmaca · A. Kafkasli
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    ABSTRACT: Objective: Our aim is to evaluate maternal and neonatal outcomes in pregnancies at 35 and older age group. Materials and Methods: Records of 4172 patients who had given birth in Inönü University School of Medicine Department of Obstetrics and Gynecology between January 1999 and February 2004 were reviewed for their mode of delivery, pregnancy complications and neonatal outcomes. The study population was stratified according to age as women <35 and women ≥35 years of age. Results: The study population consisted 3607 (86.5%) women aged <35 years, and 565 (13.5%) women aged ≥35 years. Complications of pregnancy (preeclampsia-p=0.001, antenatal bleeding-p=0.001) were higher in the ≥35 age group. Cesarean delivery rate (57.9%) was higher in ≥35 years group (p=0.001). Apgar scores at first and fifth minutes were significantly lower in ≥35 years group. Birth weight, cord pH and neonatal intensive care unit admission rates were similar in both of the groups. Conclusion: Women aged 35 years or older should be informed of the risks of pregnancy.
    No preview · Article · Mar 2005

Publication Stats

23 Citations
12.45 Total Impact Points

Institutions

  • 2012-2015
    • Dr. Zekai Tahir Burak Women's Health Research and Education Hospital
      Engüri, Ankara, Turkey
  • 2014
    • Bozok University
      Saralus, Yozgat, Turkey
  • 2011
    • Inonu University
      • Department of Obstetrics and Gynecology
      Malatia, Malatya, Turkey