Zhongwei Sun

China Agricultural University, Peping, Beijing, China

Are you Zhongwei Sun?

Claim your profile

Publications (1)4.07 Total impact

  • Zhongwei Sun · Yunlong He · Zhihong Liang · Wenwen Zhou · Tiangui Niu
    [Show abstract] [Hide abstract] ABSTRACT: A water-insoluble (1→3)-β-d-glucan isolated from the fresh fruiting bodies of Russula virescens was sulfated using sulfur trioxide-pyridine complex as reagent in dimethyl sulfoxide. Depending on the reaction conditions, the products showed different degrees of sulfation (DS) ranging from 0.17 to 1.17 and different weight average molecular weights (Mws) ranging from 2.5 × 104 to 1.2 × 105 Da. Moreover, the antitumor activities of the five sulfated derivatives against Sarcoma 180 tumor cell were tested both in vitro and in vivo. The results indicated that the native (1→3)-β-d-glucan did not show antitumor activity, while the sulfated derivatives exhibited enhanced antitumor activities. This study demonstrated that DS and Mw could influence the antitumor activities of the sulfated derivatives.
    No preview · Article · Jul 2009 · Carbohydrate Polymers

Publication Stats

23 Citations
4.07 Total Impact Points

Top Journals


  • 2009
    • China Agricultural University
      • College of Food Science and Nutritional Engineering
      Peping, Beijing, China