Franco Moriconi

Università degli Studi di Perugia, Perugia, Umbria, Italy

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Publications (11)11.12 Total impact

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    ABSTRACT: The aim of this case series is to characterize and describe traumatic lesions caused by porcupine quills involving the digital flexor tendon sheath (DFTS) in horses. Seven horses with a total of eight DFTS involved were included in the study. They underwent an in-depth diagnostic investigation followed by tenoscopic lavage. Long-term follow-up information was obtained by a telephone questionnaire to the owners of all patients included in the study. One horse did not reach the intended level of activity, whereas six horses reached the athletic levels the owners were expecting. Traumatic injuries of the DFTS caused by porcupine quills are not rare conditions where this rodent is common. The prognosis can be considered good for athletic purposes with an accurate diagnostic investigation and aggressive tenoscopic treatment, despite the fact that tendons within the sheath or ligaments adjacent to it are involved in most cases.
    No preview · Article · Jan 2015 · Journal of Equine Veterinary Science
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    ABSTRACT: A 20-year-old Argentinian gelding was evaluated for sudden weakness, muscular tremors, tachypnea, and reluctance to move. On admission, a mild bilateral hyperextension of the carpi was noticed. On the basis of the clinical, laboratory, and ultrasonographic findings, a diagnosis of diaphragmatic hernia was made. During confinement, the hyperextension of the carpi worsened. Because radiographic examination of both carpi revealed palmar-lateral diastasis of the accessory carpal bone, bilateral rupture of the palmar carpal ligament (PCL) was suspected. Gross pathology confirmed the diaphragmatic hernia and the bilateral rupture of the PCL. Rupture of a PCL in a horse has been previously described, and conformation of the forelimb of that horse was similar to that of the horse in the case described in this article.
    No preview · Article · May 2012 · Journal of Equine Veterinary Science
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    ABSTRACT: Osteoarthritis (OA) and osteochondrosis (OC) are two of the main challenges in orthopedics, whose definitive diagnosis is usually based on radiographic/arthroscopic evidences. Their early diagnosis should allow preventive or timely therapeutic actions, which are generally precluded from the poor relationships occurring between symptomatologic and radiographic evidences. These limitations should be overcome by improving the knowledge on articular tissue metabolism and on molecular factors regulating its normal homeostasis, also identifying novel OA and OC biomarkers suitable for their earlier diagnoses, whenever clinical/pathological inflammatory scenarios between these joint diseases seem somewhat related. To identify proteins involved in their aetiology and progression, we undertook a differential proteomic analysis of equine synovial fluid (SF), which compared the protein pattern of OA or OC patients with that of healthy individuals. Deregulated proteins in OA and OC included components related to inflammatory state, coagulation pathways, oxidative stress and matrix damage, which were suggestive of pathological alterations in articular homeostasis, plasma-SF exchange, joint nutritional status and vessel permeability. Some proteins seemed commonly deregulated in both pathologies indicating that, regardless of the stimulus, common pathways are affected and/or the animal joint uses the same molecular mechanisms to restore its homeostasis. On the other hand, the increased number of deregulated proteins observed in OA with respect to OC, together with their nature, confirmed the high inflammatory character of this disease. Some deregulated proteins in OA found a verification by analyzing the SF of injured arthritic joints following autologous conditioned serum treatment, an emergent therapy that provides positive results for both human and equine OA. Being the horse involved in occupational/sporting activities and considered as an excellent animal model for human joint diseases, our data provide suggestive information for tentative biomedical extrapolations, allowing to overcome the limitations in joint size and workload that are typical of other small animal models.
    Full-text · Article · Feb 2012 · Journal of proteomics
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    ABSTRACT: To evaluate changes in the cortical bone of the proximal phalanx of the fore-limbs of Thoroughbreds in response to training. Twenty-seven 2-year-old Thoroughbreds (20 females, 2 males, and 5 geldings). Horses were principally in training for races in a straight line and in a clockwise direction. Lateromedial and dorsopalmar radiographic views of each metacarpophalangeal joint were obtained before the horses started training and 1 year after starting exercise and racing. Width of the dorsal, palmar, lateral, and medial cortex and the width and thickness of the medulla were measured. Ratios (rather than absolute values) were used to remove the effect of differences in bone size among horses. 10 horses were lost from the study. Radiographs were obtained for 17 horses 1 year after starting training (9 horses raced in a clockwise direction, and 8 raced in clockwise and counterclockwise directions). There was no difference between the cortical bone in the right and left forelimbs at the start of the study. After training for 1 year, the palmar cortex in the right forelimb was significantly thicker than that in the left forelimb. The strain patterns, biomechanics of rapid exercise, and type of training most probably determined differences in the adaptive responses of the proximal phalanx. The data reported here can be used in the evaluation of weight-bearing distribution along the proximal phalanx and evaluation of the relationship between exercise and bone remodelling of the proximal phalanx.
    No preview · Article · Nov 2011 · American Journal of Veterinary Research
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    S Nannarone · R Gialletti · I Veschini · A Bufalari · F Moriconi
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    ABSTRACT: Nannarone, S., Gialletti, R., Veschini, I., Bufalari, A. and Moriconi, F., 2007. The use of alpha-2 agonists in the equine practice: comparison between three molecules. Veterinary Research Communications, 31(Suppl. 1), 309–312
    Full-text · Article · Sep 2007 · Veterinary Research Communications
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    ABSTRACT: To describe a laparoscopic technique for sterilization of the male donkey using an endoscopic linear stapler (ELS). Clinical report. Male Sardinia donkeys (n=6), aged 24-36 months. Laparoscopic sterilization was performed under standing sedation or recumbent under general anesthesia. An endoscopic linear stapler was used to transect, and control hemorrhage of, the spermatic cord. Serum testosterone concentrations were measured preoperatively and at 3, 6, and 12 months after sterilization. One testis from each of 2 donkeys was collected at 12 months for histologic examination. Sterilization was successfully achieved. The only minor intraoperative complication experienced was hemorrhage from 1 spermatic cord stump, which was re-stapled. No other major short- or long-term complications occurred. Serum testosterone concentrations were < 15 ng/dL at 3, 6, and 12 months after surgery in all donkeys. Testicular atrophy without evidence of revascularization was observed in the 2 testes examined histologically. Sterilization of descended testes by intraabdominal laparoscopic transection of the spermatic cord is a simple practical method, with minimal intraoperative or postoperative complications. Testicular revascularization did not occur. Laparoscopic sterilization in donkey can be performed using an endoscopic linear stapler as an alternative to scrotal castration.
    No preview · Article · May 2005 · Veterinary Surgery
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    ABSTRACT: Rhodococcus equi is the pathological agent of one of the most common diseases encountered in foals between 1-6 months of age and in most cases the clinical signs are present before 4 months of age. The pulmonary form with its clinical manifestation is well studied whereas the extrapulmonary diseases are less investigated. The article describes three clinical cases of extrapulmonary disease in foals (abdominal, articular and cutaneous).
    No preview · Article · Mar 2002 · Ippologia -Cremona-
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    ABSTRACT: The optimal site for microencapsulated pancreatic islet transplantation in large size-mammalians remains undetermined. Twenty-three female Large-White pigs were prospectively randomized into two groups: Group 1 (n= 11 animals) was used to assess biocompatibility as well as in vivo reactivity elicited by empty microxcapsules; Group 2 (n= 12 animals) was used to determine both the islet and the extent, if any of peri-capsular cellular overgrowth upon encapsulated islet allograft. Biocompatibility of the membrane materials was high while no activation of lymphocytes or induction of peri-capsular inflammatory cell reaction were observed. At 28 days of transplation the retrieved microencapsulated islets were fully viable and had provoked minimal inflammatory reaction at the level of the liver and omentum, with minor differences being detected in the mesentery.
    No preview · Article · Jan 2001
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    ABSTRACT: Fibrotic myopathy of the horse is an uncommon condition that has been described in the semitendinosus muscle. This paper describes a case of bilateral fibrotic myopathy of the semimembranosus muscle in a horse. The clinical examination, pathologic findings, diagnostic procedures, surgical treatment by partial myectomy, and outcome are reported.
    No preview · Article · Nov 1999

  • No preview · Article · Mar 1998 · Transplantation Proceedings

    No preview · Article · Jan 1996 · Veterinary and Comparative Orthopaedics and Traumatology

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