Hyung Jin Kim

Yeungnam University, 경산시, Gyeongsangbuk-do, South Korea

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Publications (208)337.18 Total impact

  • Hyung Jin Kim · Inchan Kim · Hogeun Lee
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    ABSTRACT: Platform-centric ecosystems run by Apple, Google, Microsoft, etc. enable the companies to magnify the values of their products and services on an unprecedented scale, by harnessing third-party add-on software such as mobile apps. Despite the importance, however, there is a dearth of empirical research that investigates how third-party developers' continued participation is actually determined. This paper examined two different mechanisms increasing dedication to a platform and constraining exit from the platform, respectively. Specific factors in each mechanism and their casual relationships were tested and discussed in the context of Apple's mobile platform.
    No preview · Article · Feb 2016
  • Hyung Jin Kim · Woong Ki Jang · Byeong Hee Kim · Young Ho Seo
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    ABSTRACT: This paper presents the effect of micropost arrangements on the meniscus shape of the advancing liquid front for capillary filling in a microchannel of biomedical diagnostic sensors. Four different arrangements of cylindrical microposts inside microchannels including hexagonal array with smooth sidewall, hexagonal array with rugged sidewall, rectangular array with smooth sidewall, and rectangular array with rugged sidewall were considered. The meniscus shape of the fluid front were estimated by the volume-of-fluid based computational simulation and compared with experimental results. For hexagonal array, overall meniscus shapes of the advancing liquid front were concave form regardless of sidewall shape. On the other hand, capillary filling through rectangular arrangement of microposts occurred as a step-wise movement with maintaining the flat shape of the advancing liquid fronts. Sidewall microposts affected the capillary filling times rather than the meniscus shape of advancing liquid front. The shape of advancing liquid front and capillary filling time could be passively controlled by arrangement of microposts inside microchannel.
    No preview · Article · Jan 2016 · International Journal of Precision Engineering and Manufacturing
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    ABSTRACT: Introduction: Peripheral facial palsy is rarely caused by primary neoplasms, which are mostly constituted of tumors of the central nervous system, head and neck, and leukemia. Presentation of case: A 2-month-old male infant presented with asymmetric facial expression for 3 weeks. Physical examination revealed suspicious findings of right peripheral facial palsy. Computed tomography of the temporal bone revealed a suspicious bone tumor centered in the right petrous bone involving surrounding bones with extension into the middle ear cavity and inner ear. Subtotal resection of the tumor was performed due to crucial structures adjacent the mass. Histopathology and immunohistochemistry of the resected tumor was consistent with primitive neuroectodermal tumor. Conclusion: We report a rare case of a primitive neuroectodermal tumor located at the skull base presenting with only peripheral facial palsy.
    Preview · Article · Dec 2015 · International Journal of Surgery Case Reports
  • Hyung Jin Kim · J K Park · S C Park · Y G Kim · H Choi · J I Ko · M K Kim · Y B Jeong · Y S Shin
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    ABSTRACT: Objectives: This study was designed to evaluate the causative organisms in young male soldiers with clinical signs and symptoms after sexual contact that suggests a diagnosis of urethritis. Methods: Between June 2012 and January 2015, male patients with urethritis symptoms that had resulted from sexual contact within 3 months participated in this study. All patients were evaluated using urinalysis and were screened for Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Ureaplasma urealyticum (UU), Mycoplasma genitalium (MG), Mycoplasma hominis (MH), herpes simplex virus (HSV) type II and Trichomonas vaginalis (TV) using multiplex PCR (mPCR) assay in order to detect sexually transmitted infections (STI) or pathogens. Results: A total of 436 male patients aged 18-28 years were included in the study. The median age was 22.0 years. The prevalence of STI pathogens were as follows: NG in 19.0%, CT in 36.6%, UU in 24.0%, MG in 21.5%, MH in 6.1%, HSV type II in 1.6%, TV in 0.2% and indeterminate STI pathogens in 9.4%. Coinfection of NG with non-NG was detected in 5.7% of the participants, while the coinfection rates for STI pathogens were: with CT in 3.4%, with UU in 2.7%, with MG in 0.2% and with MH in 0.2%. Conclusions: CT was the most prevalent STI pathogen and coinfections of NG with non-NG appeared less frequently. The young male soldiers with urethritis should be administered suitable antibiotics for STI pathogens that were found by mPCR results, rather than an experimental combination of antibiotics for coinfections.
    No preview · Article · Nov 2015 · Journal of the Royal Army Medical Corps
  • Hyung Jin Kim · Chanam Lee
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    ABSTRACT: Background: A public elementary school has traditionally functioned as an important center of a neighborhood, but this role has diminished with sprawling urban developments. Despite the large number of studies of children's walking to/from school (WTS), the school's location in relation to the larger neighborhood context has not been fully explored. This study is to examine the relationship between school's spatial centrality and children's WTS in urban, suburban and rural settings. Methods: this study used school travel tally (11,721 students), environment audit, GIS and census data from 71 elementary school/neighborhoods in Texas, and employed the closeness centrality index to estimate a school's spatial centrality. Data were collected from 2009 to 2012. Results: After controlling for neighborhood characteristics, it was found that more centrally located schools are likely to have higher proportions of WTS in the neighborhoods. And, among urban, suburban and rural settings, urban schools were the most and rural schools were the least likely to be centrally-located in the neighborhoods. Conclusions: The findings offer implications on school and community planning policies that can help promote WTS. Spatial centrality measures can be effective tools to identify environmental factors in complex urban networks related to human behaviors and community-based activities.
    No preview · Article · Nov 2015 · Journal of Physical Activity and Health
  • Eun Chang Choi · Hyung Jin Kim · Jin-Hyo Boo · Byungyou Hong
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    ABSTRACT: Electron transport in DSSCs with the TiO2 nanoparticles photoanode become more difficult by the tremendous grain boundaries and disordered pore structures. So, one-dimensional nanostructures have great attractions due to the increased carrier diffusion length by a structural property such as direct pathways for electron transport. In this study, we investigated DSSCs using ZnO nanorod arrays and ZnO nanoparticle/nanorod composite layer as a photoanode. To prevent aggregation of ZnO nanorods, ZnO nanorods were synthesized on the nano-patterned seed dots using ultra-thin porous AAO template fabricated by new method. We confirmed that ZnO naonrods were sparsely grown as the nano-patterned seed dots were used.
    No preview · Article · Nov 2015 · Journal of Nanoscience and Nanotechnology
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    ABSTRACT: The design and the assembly of the quarter-wave resonator (QWR) and half-wave resonator (HWR) cryomodules for RAON are shown. The cryomodule is optimized for heat loads due to superfluid helium at 2 K, supercritical helium at 4.5 K and the thermal shield at 40 K. The cryomodule consists of a vacuum chamber, a magnetic shield, a thermal shield, a cryogenic pipe line and a support bar.
    No preview · Article · Oct 2015 · Journal- Korean Physical Society
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    ABSTRACT: We evaluated the tumor response and survival according to the KRAS oncogene status in locally advanced rectal cancer. One hundred patients with locally advanced rectal cancer (cT3-4N0-2M0) received preoperative radiation of 50.4 Gy in 28 fractions with 5-fluorouracil and total mesorectal excision. Tumor DNA from each patient was obtained from pretreatment biopsy tissues. A Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation was found in 26 (26%) of the 100 patients. Downstaging (ypT0-2N0M0) rates after preoperative chemoradiotheray were not statistically different between the wild-type and mutant-type KRAS groups (30.8% vs 27.0%, P = 0.715, respectively). After a median follow-up time of 34 months, there was no statistically significant difference in the 3-year relapse-free survival (82.2% vs 82.6%, P = 0.512) and overall survival (94.7% vs 92.3%, P = 0.249) rates between wild-type and mutant-type KRAS groups, respectively. The KRAS mutation status does not influence the tumor response to the radiotherapy and survival in locally advanced rectal cancer patients who received preoperative chemoradiotherapy and curative surgery.
    Full-text · Article · Aug 2015 · Medicine
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    Sang Hun Kim · Hyung Jin Kim · Ki Tae Jung
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    ABSTRACT: Increase in intracranial pressure (ICP) is one of the physiologic changes during laparoscopic surgery, which is known to be associated with positional changes. Changes of ICP can be measured directly by invasive method, but ultrasonographic measurement of optic nerve sheath diameter (ONSD) is known to be a rapidly applicable technique for evaluating ICP. The aim of this study is to investigate the change of ONSD according to the positional change during laparoscopic surgery. Female patients scheduled to undergo laparoscopic surgery were enrolled. Fifty-seven patients were assigned according to the position during surgery (Group T: gynecological surgery, Trendelenburg position, n = 27 vs. Group RT: laparoscopic cholecystectomy, Reverse trendelenburg position, n = 30). After induction of anesthesia, ONSD, PaCO2, end-tidal carbon dioxide (ETCO2), and mean arterial pressure (MAP) were measured. Parameters were measured at 6 time points during surgery. There were no significant differences in the demographic data of patients, procedure time, and anesthesia. After pneumoperitoneum and positional change, ONSD, ETCO2, and MAP increased in both groups until 15 min and returned to the baseline. However, no significant differences in changes of ONSD, PaCO2, ETCO2, and MAP were observed between two groups. ONSD during laparoscopic surgery with pneumoperitoneum increased slightly until 15 minutes, but there were no significant differences according to the position. Increases in ICP during laparoscopic surgery with short period of pneumoperitoneum would be small in disregard of position in patients without intracranial pathology.
    Full-text · Article · Aug 2015 · Korean journal of anesthesiology
  • Heetae Kim · Yong Sik Chang · Wookang Kim · Yong Woo Jo · Hyung Jin Kim

    No preview · Article · Jul 2015
  • Hyung Jin Kim · YS Shin · H Choi · M K Kim · YB Jeong · J K Park
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    ABSTRACT: We present a case of undiagnosed nephrogenic diabetes insipidus as a cause of acute urinary retention in a 21-year-old male soldier. Soldiers live in close quarters, and have a regimented lifestyle that may not allow for frequent voiding; therefore, undiagnosed nephrogenic diabetes insipidus may result in acute urinary retention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
    No preview · Article · Jul 2015 · Journal of the Royal Army Medical Corps
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    ABSTRACT: Effective intracellular level of a platinum anti-cancer drug, cisplatin, following repeated injections can be decreased either by the active efflux via ATP pump or by interactions with glutathione and metallothionein. Cisplatin in cytoplasm preferably binds to cysteine-rich proteins such as glutathione and metallothionein (MT). Detoxification of cisplatin by intracellular thiol-containing proteins has been considered to be major hurdles to overcome. The short hairpin RNA targeting MT (shMT) was tested to down-regulate MT and recover cisplatin resistance. A reducible polymer, poly(oligo-D-arginine) (rPOA), formed stable complex with shMT and demonstrated superior transfection efficiency. Efficient transfection of shMT/rPOA oligo-peptoplexes was found to significantly inhibit MT over-expression, resulting in 45% decrease of cell viability compared to the cisplatin alone group. This decrease was mediated by synergistic effect of shMT/rPOA oligo-peptoplex and cisplatin. Co-administration of shMT/rPOA oligo-peptoplex and cisplatin in in vivo tumor model showed noticeable tumor-suppressing effect by inducing reversal of cisplatin resistance following effective intracellular delivery of shMT by rPOA. Combination therapy through co-administration of shMT/rPOA oligo-peptoplex and cisplatin was found to effectively reverse cisplatin resistance by RNA interference and consequently improve anti-cancer activity of cisplatin. Copyright © 2015. Published by Elsevier B.V.
    No preview · Article · Jul 2015 · Journal of Controlled Release
  • Hee Jun Ahn · Hyung Jin Kim · Dong Hoon Jin · Nam Joo Hong
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    ABSTRACT: A new and relatively simple spectrophotometric technique has been developed for the accurate determination of α-factor pheromone affinities for Ste2p whole cell receptor in yeast a-cells. We designed and tested nine detector peptides containing mono- (ε412 = 14 500) or tri-cysteine residues (ε412 = 43 660). The free unbound detector was detected using Ellman's reagent at 412 nm. Saturation binding studies using Saccharomyces cerevisiae Y 7925 (MATa) at a concentration of 2.5 × 1011 cells/mL with the highest affinity detector 1, [Orn6]α-factor-[Cys]3, resulted in a dissociation constant (KD) of 1.67 × 10-7 and total binding sites per cell (Bcell = 29 500 sites/cell) comparable with those obtained using radiolabeled binding assays. Competitive binding assay using five nonchromogenic α-factor analogs allowed for the determination of each KD value. [Orn6,D-Ala9]α-factor showed the highest receptor affinity (KD = 1.03 × 10-7 M), which was threefold higher than that of native α-factor. This assay provides rapid and convenient results for determining the relative affinities of nonchromogenic α-factors and eliminates the need for radioactive waste disposal. © 2015 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Wiley.
    No preview · Article · Jul 2015 · Bulletin of the Korean Chemical Society
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    Full-text · Dataset · Feb 2015
  • D.-Y. Kim · Heemoon Kim · Hyung Jin Kim
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    ABSTRACT: This article describes the preparation and pH-sensing characteristics of a sol-gel-based optical sensor. Afluorescent dye possessing a triethoxysilane pendant group (2) was synthesized and covalently immobilized onto a sol-gel matrix to afford an optically pH-sensitivemembrane that operates in acidic solutions. The sensor membrane displays two distinctive absorption bands around 374 and 439 nm, and two emission bands around 520 with excitation at 340 and 460 nm. The fluorescence intensity and absorbance ratio of the sensor membrane increases as the pH increases from -1.0 to 2.0. The sensor membrane was reproducible, reversible, and stable for repeated measurements in acidic buffer solutions and has a long lifetime of at least a month without dye leaching. © 2015 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
    No preview · Article · Feb 2015 · Bulletin- Korean Chemical Society
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    ABSTRACT: Screening for second primary cancer (SPC) is one of the key components to survivorship care. We aim to evaluate the oncologists' experience with SPCs and assess the current practice, perceived barriers, and recommendations related to SPC screening. A nationwide survey was conducted with a representative sample of 496 Korean oncologists. A questionnaire based on the findings from our previous qualitative study was administered. More than three-fourths of oncologists (76.3%), who participated in the study, had experience with SPC patients. Over half of them (51.9%) stated that it was an embarrassing experience. While the current management practice for SPC varies, most oncologists (80.2%) agreed on the necessity in proactively providing information on SPC screening. A short consultation time (52.3%), lack of guidelines and evidence on SPC screening (47.7%), and patients' lack of knowledge about SPCs (45.1%) or SPC screening (41.4%) were most frequently reported as barriers to providing appropriate care for managing SPC. Oncologists recommended the development of specific screening programs or guidelines in accordance to the type of primary cancer (65.9%), the development of an internal system for SPC screening within the hospital (59.7%) or systematic connection with the national cancer screening program (44.3%), and education of oncologists (41.4%) as well as patients (48.9%) regarding SPC screening. Many oncologists reported the occurrence of SPC as an embarrassing experience. Given the variations in current practice and the lack of consensus, further studies are warranted to develop the optimal clinical strategy to provide SPC screening for cancer survivors.
    Preview · Article · Feb 2015 · Cancer Research and Treatment
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    Hyuk Jin Cha · Hoe Chun Jung · Hyung Jin Kim
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    ABSTRACT: The design and the fabrication of superconducting cavities for the Korean heavy ion accelerator, RAON, are in progress. In this paper, we present the progress towards the design of a SSR1 single spoke resonator (β = 0.3 and f = 325 MHz). Not only electromagnetic and mechanical analyses for the cavity but also the issues that should be considered when fabricating and operating the cavity are discussed. In addition, a variant of the SSR1 cavity for more efficient performance is proposed with its electromagnetic analyses.
    Full-text · Article · Feb 2015 · Journal- Korean Physical Society
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    ABSTRACT: The Rare Isotope Science Project (RISP) has been proposed as a multi-purpose accelerator facility for providing beams of exotic rare isotopes of various energies. The RISP driver linac, which is used to accelerate the beam, for example, uranium ions from 0.5 MeV/u to 200 MeV/u, consists of superconducting RF cavities and warm quadrupole magnets for focusing heavy-ion beams. The requirements for the linac design are especially high for acceleration of multiple charge beams. In this paper, we present the RISP linac’s design, the superconducting cavity, the cryomodule system, and the requirements in the dynamic errors to minimize the beam centroid’s oscillation.
    No preview · Article · Feb 2015 · Journal- Korean Physical Society
  • Dae-Young Kim · Hyung Jin Kim
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    ABSTRACT: Highly sensitive pH optode membranes for operation at low pH values were fabricated by the covalent immobilization of an ICT dye (DPA) on a silanized glass surface. The photo-initiated copolymerization of DPA with 2-hydroxyethyl methacrylate (HEMA) and diacrylamidated poly(dimethylsiloxane) (PSA) or triethylene glycol dimethacrylate as a cross-linker gave pH-sensitive optode membranes (M1 and M2) capable of working in highly acidic condition. The fluorescence intensities of the membranes increased with increasing pH in the pH range of −1.0 to 2.0. Both membranes were useful as a ratiometric pH optode in the same acidic pH range. Optode membrane M1 prepared by using PSA was more sensitive to pH change than was M2. The prepared membranes were characterized in terms of pKa values, optimal thickness, effect of ionic strength, response time, and leaching of dye.
    No preview · Article · Jan 2015 · Sensors and Actuators B Chemical
  • Kang‐Hyeon Kim · Hyung Jin Kim
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    ABSTRACT: To develop an optode membrane with a high sensitivity and a wide detection range, a photoinduced electron transfer fluorescence dye (FWSA) possessing an acrylate moiety was synthesized and covalently immobilized on a 2-hydroxyethyl methacrylate-based network polymer matrix. The prepared membranes displayed the fluorescence "turn-on" detection of water over a wider operating sensing range. The sensitivity of the optode membrane was influenced by the crosslinker. The sensitivity of the membrane M1 using dimethacrylamidated poly(dimethylsiloxane) (AMPS) as a crosslinker was superior to that of M2 and M3 membranes using tetra- or triethylene glycol dimethacrylate. As the water content was increased from 0 to 80% in water-miscible organic solvents, the M1 membrane showed a gradual fluorescence enhancement. The sensing performance of the M1 membrane was evaluated for aqueous methanol, ethanol, acetone, and dimethyl sulfoxide solutions in terms of the detection range, response time, reproducibility, and stability. © 2015 Korean Chemical Society , Seoul & Wiley-VCH Verlag GmbH & Co. KGaA , Weinheim.
    No preview · Article · Jan 2015 · Bulletin of the Korean Chemical Society

Publication Stats

2k Citations
337.18 Total Impact Points


  • 2015
    • Yeungnam University
      • School of Biotechnology
      경산시, Gyeongsangbuk-do, South Korea
    • Korea Basic Science Institute KBSI
      Sŏul, Seoul, South Korea
  • 2014-2015
    • Gumi Electronics and Information Technology Research Institute
      Kibi, Gyeongsangbuk-do, South Korea
    • Chosun University
      Gwangju, Gwangju, South Korea
  • 2009-2015
    • Chonbuk National University
      Tsiuentcheou, Jeollabuk-do, South Korea
  • 2008-2015
    • Catholic University of Korea
      • College of Medicine
      Sŏul, Seoul, South Korea
    • Kyung Hee University
      • Department of Mechanical Engineering
      Sŏul, Seoul, South Korea
  • 2007-2015
    • Hanyang University
      • • College of Engineering
      • • Department of Computer Science and Engineering
      • • Division of Chemical Engineering and Bioengineering
      Sŏul, Seoul, South Korea
  • 2000-2015
    • Chonnam National University
      • School of Applied Chemical Engineering
      Gwangju, Gwangju, South Korea
  • 2013-2014
    • Kangwon National University
      • Department of Mechanical and Mechatronics Engineering
      Shunsen, Gangwon-do, South Korea
    • National University of Singapore
      Tumasik, Singapore
    • Hallym University
      Sŏul, Seoul, South Korea
    • Seoul National University Hospital
      • Department of Radiology
      Sŏul, Seoul, South Korea
  • 2012-2014
    • Kansas State University
      • Department of Landscape Architecture/Regional and Community Planning
      Kansas, United States
  • 2010-2014
    • St. Vincent Hospital
      Green Bay, Wisconsin, United States
    • National Cancer Center Korea
      QYK, Gyeonggi-do, South Korea
  • 2006-2014
    • Wonkwang University
      • Department of Dentistry
      Riri, North Jeolla, South Korea
    • Sungkyunkwan University
      • • Department of Radiology
      • • College of Information and Communication Engineering (SoICE)
      • • Department of Chemistry
      Sŏul, Seoul, South Korea
    • Gyeongsang National University
      • Department of Mechanical Engineering
      Shinshū, Gyeongsangnam-do, South Korea
    • Yonsei University Hospital
      Sŏul, Seoul, South Korea
  • 2004-2014
    • Chonbuk National University Hospital
      Sŏul, Seoul, South Korea
    • Kwandong University
      Gangneung, Gangwon, South Korea
  • 2002-2014
    • Inha University Hospital
      Sinhyeon, Gyeongsangnam-do, South Korea
  • 2001-2014
    • Inha University
      • • Department of Pediatrics
      • • College of Medicine
      • • Department of Radiology
      Chemulpo, Incheon, South Korea
  • 2006-2012
    • Seoul National University
      • • Department of Pathology
      • • Department of Physics and Astronomy
      Sŏul, Seoul, South Korea
  • 2011
    • University of Suwon
      Suigen, Gyeonggi Province, South Korea
    • Texas A&M University
      • Department of Landscape Architecture and Urban Planning
      College Station, Texas, United States
    • Seoul Medical Center
      Sŏul, Seoul, South Korea
  • 2001-2011
    • Yonsei University
      • • Department of Urban Planning and Engineering
      • • Department of Forensic Medicine and Brain Korea 21 Project for Medical Science
      Sŏul, Seoul, South Korea
  • 2005-2010
    • Samsung Medical Center
      • Department of Radiology
      Sŏul, Seoul, South Korea
    • Hong-ik university
      United States
    • Johns Hopkins University
      • Department of Chemistry
      Baltimore, Maryland, United States
    • The Australian Society of Otolaryngology Head & Neck Surgery
      Evans Head, New South Wales, Australia
  • 2006-2009
    • Korea University
      • College of Medicine
      Sŏul, Seoul, South Korea
  • 1992
    • University of California, Davis
      • Department of Chemistry
      Davis, California, United States