Tae Hoon Kim

Inje University, Kŭmhae, Gyeongsangnam-do, South Korea

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Publications (482)1235.55 Total impact

  • Seung Pyo Jung · Dong Hoon Lee · Tae Hoon Kim · Ju Sung Park

    No preview · Article · Feb 2016
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    ABSTRACT: Purpose: Glufosinate poisoning can cause neurologic complications that may be difficult to treat due to delayed manifestation. Studies assessing possible predictors of complications are lacking. Although serum ammonia level is a potential predictor of severe neurotoxicity, it has only been assessed via case reports. Therefore, we investigated factors that predict neurologic complications in acute glufosinate-poisoned patients. Materials and Methods: We conducted a retrospective review of 45 consecutive glufosinate-poisoning cases that were diagnosed in the emergency department (ED) of Wonju Severance Christian Hospital between May 2007 and July 2014. Patients with a Glasgow Coma Scale (GCS) score of <8, seizure, and/or amnesia were defined to a neurologic complication group. Results: The neurologic complication group (29 patients, 64.4%) comprised patients with GCS<8 (27 patients, 60.0%), seizure (23 patients, 51.1%), and amnesia (5 patients, 11.1%). Non-neurologic complications included respiratory failure (14 patients, 31.1%), intubation and ventilator care (23 patients, 51.1%), shock (2 patients, 4.4%), pneumonia (16 patients, 35.6%), acute kidney injury (10 patients, 22.2%), and death (4 patients, 8.9%). Complications of GCS<8, seizure, respiratory failure, and intubation and ventilator care appeared during latent periods within 11 hrs, 34 hrs, 14 hrs, and 48 hrs, respectively. Initial serum ammonia was a predictor of neurologic complications [odds ratio 1.039, 95% confidence interval (1.001–1.078), p=0.046 and area under the curve 0.742]. Conclusion: Neurologic complications developed in 64.4% of patients with acute glufosinate poisoning. The most common complication was GCS<8. Initial serum ammonia level, which can be readily assessed in the ED, was a predictor of neurologic complications.
    Full-text · Article · Jan 2016 · Yonsei Medical Journal
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    Myoung-Kwon Kim · Tae Hoon Kim · Seong-Gil Kim
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    ABSTRACT: [Purpose] This study aimed to investigate the correlation between the cognitive level of the elderly and their attitude towards the living environment. [Subjects and Methods] A total of 80 elderly people hospitalized in a nursing home in K city, South Korea, participated in this study. Pearson correlation analysis was used to test the relationships between scores on the Mini Mental State Examination-Korean Version and Measurement of Quality of the Environment (facilitators and obstacles). [Results] A positive and moderately strong correlation (r = 0.462) was found between scores on the Mini Mental State Examination and the Measurement of Quality of the Environment (obstacle). [Conclusion] In a nursing home, patients with relatively higher cognitive levels can perceive more obstacles in the surrounding environment.
    Preview · Article · Dec 2015 · Journal of Physical Therapy Science
  • Hye Rim Suh · Tae Hoon Kim · Gyeong-Soon Han
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    ABSTRACT: Work-related musculoskeletal symptom disorders (WMSDs) have a significant issue for dental professionals. This study investigated the effects of high-frequency transcutaneous electrical nerve stimulation (TENS) on work-related pain, fatigue, and the active range of motion in dental professionals. Among recruited 47 dental professionals with WMSDs, 24 subjects received high-frequency TENS (the TENS group), while 23 subjects received placebo stimulation (the placebo group). TENS was applied to the muscle trigger points of the levator scapulae and upper trapezius, while placebo-TENS was administered without electrical stimulation during 60 min. Pain and fatigue at rest and during movement were assessed using the visual analog scale (VAS), pain pressure threshold (PPT), and active range of motion (AROM) of horizontal head rotation at six time points: prelabor, postlabor, post-TENS, and at 1 h, 3 h, and 1 day after TENS application. Both groups showed significantly increased pain and fatigue and decreased PPT and AROM after completing a work task. The TENS group showed significantly greater improvements in VAS score, fatigue, PPT, and AROM at post-TENS and at 1 h and 3 h after application (all P < 0.05) as compared to the placebo group. A single session high-frequency TENS may immediately reduce symptoms related to WMSDs in dental professionals.
    No preview · Article · Dec 2015 · Evidence-based Complementary and Alternative Medicine
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    ABSTRACT: Background: The anatomical lung volume is conventionally measured by computed tomography (CT). However, chest radiographs could be considered as an alternative method with low cost and low radiation. Purpose: To predict the anatomical lung volume using planimetric measurements of chest radiographs. Material and methods: In total, 119 participants (M:F ratio = 66:53; age, 53.7 ± 9.6 years) who underwent chest CT for lung cancer screening were enrolled. The lung volume on CT was measured as a reference for the anatomical lung volume. To eliminate the bias from the degree of inspiration, virtual chest radiographs (posterior-anterior view and lateral view) were generated from the CT images using the thick multiplanar technique, and the lung area (cm(2)) was measured in the right (P), left (Q), and lateral (R) lungs according to the planimetric method. A regression equation predicting the anatomical lung volume from the planimetric measurements was generated. The correlation between the measured and estimated lung volumes was evaluated. The percentage error rate (%) was calculated and the equation was validated internally and externally. Results: The equation predicting the anatomical lung volume (mL) was 9.6*S-1367, where the summed lung area (S) was defined as (P + Q + R). The measured and estimated lung volumes were highly correlated (R = 0.941, P < 0.001). The absolute error rate was 5.7 ± 4.9%. The root mean square error of the equation was 290.2. The root mean square errors on internal and external validation were 300.4 and 267.0. Conclusion: The anatomical lung volume may be feasibly and accurately predicted from planimetric measurements of chest radiographs.
    No preview · Article · Dec 2015 · Acta Radiologica
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    ABSTRACT: A two-month-old infant presented with coarctation of the aorta, severe left ventricular dysfunction, and moderate to severe mitral regurgitation. Through median sternotomy, the aortic arch was repaired under cardiopulmonary bypass and regional cerebral perfusion. The patient was postoperatively supported with a left ventricular assist device for five days. Left ventricular function gradually improved, eventually recovering with the concomitant regression of mitral regurgitation. Prompt surgical repair of coarctation of the aorta is indicated for patients with severe left ventricular dysfunction. A central approach for surgical repair with a back-up left ventricular assist device is a safe and effective treatment strategy for these patients.
    Preview · Article · Dec 2015 · Korean Journal of Thoracic and Cardiovascular Surgery
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    ABSTRACT: Live attenuated vaccines are used for effective protection against fowl typhoid (FT) in domestic poultry. In this study, a lon/cpxR/asd deletion mutant of Salmonella Gallinarum expressing the B subunit of a heat labile toxin (LTB) from Escherichia coli, a known adjuvant, was cloned in a recombinant p15A ori plasmid, JOL1355, and evaluated as a vaccine candidate in chickens. The plasmid was shown to be stable inside the attenuated Salmonella Gallinarum cell after three successive generations. Moreover, from an environmental safety point of view, apart from day 1 the JOL1355 strain was not detected in feces through day 21 postinoculation. For the efficacy of JOL1355, a total of 100 chickens were equally divided into two groups. Group A (control) chickens were intramuscularly inoculated with phosphate-buffered saline at 4 and 8 wk of age. Group B chickens were primed and boosted via the intramuscular route with 200 μL of a bacterial suspension of JOL1355 containing 1 × 10(8) colony forming units. All the chickens in Group A and B were challenged at 3 wk postbooster by oral inoculation with a wild-type Salmonella Gallinarum strain, JOL420. The JOL1355-immunized group showed significant protection and survival against the virulent challenge compared to the nonimmunized group. In addition, Group B exhibited a significantly higher humoral immune response, and the chickens remained healthy without any symptoms of anorexia, diarrhea, or depression. Group B also exhibited a significantly lower mortality rate of 4% compared to the 46% of the control group, which can be attributed to higher immunogenicity and better protection. The Group B chickens had significantly lower lesion scores for affected organs, such as the liver and spleen, compared to those of the control chickens (P < 0.01). These findings suggest that JOL1355 is a promising candidate for a safe and highly immunogenic vaccine against FT.
    No preview · Article · Dec 2015 · Avian Diseases
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    Preview · Article · Nov 2015 · Archives of Plastic Surgery
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    ABSTRACT: Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting that HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide after perturbation of elongation with small molecule inhibitors. We found that HDACI-mediated repression requires heat shock protein 90 (HSP90) activity. HDACIs promote the association of RNA polymerase II (RNAP2) and negative elongation factor (NELF), a complex stabilized by HSP90, at the same genomic sites. Additionally, HDACIs redistribute bromodomain-containing protein 4 (BRD4), a key elongation factor involved in enhancer activity. BRD4 binds to newly acetylated sites, and its occupancy at promoters and enhancers is reduced. Furthermore, HDACIs reduce enhancer activity, as measured by enhancer RNA production. Therefore, HDACs are required for limiting acetylation in gene bodies and intergenic regions. This facilitates the binding of elongation factors to properly acetylated promoters and enhancers for efficient elongation.
    Preview · Article · Nov 2015 · Cell Reports
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    ABSTRACT: We evaluated the feasibility of sub-millisievert (mSv) coronary CT angiography (CCTA) using low tube voltage, prospective ECG gating, and a knowledge-based iterative model reconstruction algorithm. Twenty-four non-obese healthy subjects (M:F 13:11; mean age 50.2 ± 7.8 years) were enrolled. Three sets of CT images were reconstructed using three different reconstruction methods: filtered back projection (FBP), iterative reconstruction (IR), and knowledge-based iterative model reconstruction (IMR). The scanning parameters were as follows: step-and-shoot axial scanning, 80 kVp, and 200 mAs. On the three sets of CT images, the attenuation and image noise values were measured at the aortic root. The signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR) were calculated at the proximal right coronary artery and the left main coronary artery. The qualitative image quality of the CCTA with IMR was assessed using a 4-point grading scale (grade 1, poor; grade 4, excellent). The mean radiation dose of the CCTA was 0.89 ± 0.09 mSv. The attenuation values with IMR were not different from those of other reconstruction methods. The image noise with IMR was significantly lower than with IR and FBP. Compared to FBP, the noise reduction rate of IMR was 69 %. The SNR and CNR of CCTA with IMR were significantly higher than with FBP or IR. On the qualitative analysis with IMR, all included segments were diagnostic (grades 2, 3, and 4), and the mean image quality score was 3.6 ± 0.6. In conclusion, CCTA with low tube voltage, prospective ECG gating, and an IMR algorithm might be a feasible method that allows for sub-millisievert radiation doses and good image quality when used with non-obese subjects.
    No preview · Article · Nov 2015 · The international journal of cardiovascular imaging
  • Mi Jung Lee · Jong Ik Lee · Tae Hoon Kim · Joohan Lee · Keisuke Nagao
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    ABSTRACT: New K/Ar ages and geochemical and isotope data (Sr, Nd, Pb) of submarine samples from the Terror Rift Region and subaerial lavas from Mt. Melbourne Volcanic Field (MMVF) in the western Ross Sea, Antarctica, are presented. The MMVF samples are classified into Groups A and B based on their temporal and spatial distribution. All samples are alkaline, ranging from basanite to trachybasalt, and exhibit the Ocean Island Basalt (OIB)-like patterns of trace element distribution, with a prominent depletion in K and Pb. New K/Ar ages and geochemical data of the studied samples show no correlations between age and their compositions and suggest that they represent products of three different magmatic episodes. The Terror Rift submarine lavas (0.46–0.57 Ma) display a distinct trend, with more primitive geochemical characteristics (higher MgO (7.2–9.8 wt%) and CaO (9.9–11.9 wt%) and stronger HIMU signature (higher 206Pb/204Pb and 143Nd/144Nd ratios, and less radiogenic 87Sr/86Sr) than those of MMVF basalts. Results from a rare earth element (REE) model suggest that the Terror Rift submarine lavas are derived from small degrees (1–2%) of partial melting of an amphibole-bearing garnet peridotite mantle source. Despite the distinctly different ages and locations of the MMVF Group A (0.16–0.33 Ma) and B (1.25–1.34 Ma) basalts, they show similar geochemical and isotopic features, indicating the sharing of common mantle sources and magma processes during magma generation. Incompatible trace element ratios (e.g., Ba/Nb = 6.4–13.2, La/YbN = 14.4–23.2, Dy/Yb = 2.2–3.0) and isotopic compositions of the MMVF Group A and B volcanics suggest derivation from higher degrees (2–5%) of partial melting of an amphibole bearing garnet peridotite source and strong influence of an EMI-type mantle source. The stronger HIMU signature of the Terror Rift submarine lavas appears to be related to smaller degrees of partial melting, suggesting predominant contribution of the HIMU component to the less partially melted rocks from the Cenozoic NVL magmatism. In contrast, the higher degree of MMVF A and B magmas can be explained by greater interaction with heterogeneous lithospheric mantle, resulting in a diluted HIMU signature compared with that of the Terror Rift submarine lavas. We assume that HIMU- and EMI-type mantle components incorporated in the Cenozoic NVL magmas originated from sub-continental lithospheric mantle metasomatized by plume or subduction-related fluids prior to the breakup of Gondwanaland. © 2015 The Association of Korean Geoscience Societies and Springer-Verlag Berlin Heidelberg
    No preview · Article · Oct 2015 · Geosciences Journal
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    ABSTRACT: We evaluated the feasibility of using quantitatively measured thoracic components, as compared to body mass index (BMI), for predicting the image noise of coronary computed tomography angiography (CCTA). One hundred subjects (M:F = 64:36; mean age, 55 ± 8.8 years) who underwent prospective electrocardiography-gated CCTA and low-dose chest computed tomography (CT) were analyzed retrospectively. The image noise of the CCTA was determined by the standard deviation of the attenuation value in a region of interest on the aortic root level. On the low-dose chest CT, the areas of the thoracic components were measured at the aortic root level. An auto-segmentation technique with the following threshold levels was used: quantitatively measured area of total thorax [QMAtotal: -910 to 1000 Hounsfield units (HU)], lung (QMAlung: -910 to -200 HU), fat (QMAfat: -200 to 0 HU), muscle (QMAmuscle: 0-300 HU), soft tissue (fat + muscle, QMAsoft tissue: -200 to 300 HU), bone (QMAbone: 300-1000 HU) and solid tissue (fat + muscle + bone, QMAsolid tissue: -200 to 1000 HU). The relationship between image noise and variable biometric parameters including QMA was analyzed, and the linear correlation coefficients were used as indicators of the strength of association. Among the variable biometric parameters, including BMI, QMAsolid tissue showed the highest correlation coefficient with image noise in all subjects (r = 0.804), males (r = 0.716), females (r = 0.889), the overweight (r = 0.556), and the non-overweight subgroups (r = 0.783). QMAsolid tissue can be used as a potential surrogate predictor of the image noise level in low tube voltage CCTA.
    No preview · Article · Oct 2015 · The international journal of cardiovascular imaging
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    ABSTRACT: Objectives: Controversy is continuing over the need for ventilation and the optimal compression-ventilation (CV) ratio during cardiopulmonary resuscitation (CPR). The aim of this study was to comparatively elucidate the effect on hemodynamics and arterial oxygen saturation of a single ventilation relative to two consecutive ventilations during CPR in a dog model of cardiac arrest. Methods: Twenty mongrel dogs were divided into two groups. After 3 minutes of ventricular fibrillation (VF), the single-ventilation group received CPR with a 30:1 CV ratio, and the two-ventilation group received CPR with a 30:2 CV ratio, all with room air for 7 minutes. Thereafter, continuous chest compressions and intermittent ventilation at rate of 10 per minute were followed for both groups for 10 minutes. Hemodynamic parameters, arterial blood gas profiles, and variables from CPR were compared at baseline and at 5, 10, 15, and 20 minutes after induction of VF. Results: Hemodynamic parameters including aortic systolic and diastolic pressures, right atrial systolic and diastolic pressures, coronary perfusion pressure, end-tidal carbon dioxide tension, and arterial blood gas profiles including arterial oxygen tension, arterial oxygen saturation, and arterial carbon dioxide tension were not different between two groups during CPR. In the 30:1 group, the period of compression interruption was shorter and chest compression fraction was higher than that in the 30:2 group (6 sec/min vs. 10.9 sec/min, p < 0.001; 90.0% vs. 81.8%, p < 0.001). Conclusions: CPR with a 30:1 CV ratio, compared to CPR with a 30:2 CV ratio, results in comparable arterial oxygenation saturation and hemodynamics.
    No preview · Article · Oct 2015 · Academic Emergency Medicine
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    ABSTRACT: AT-rich interactive domain 1A gene (ARID1A) loss is a frequent event in endometriosis-associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside the uterus, and 50% of women with endometriosis are infertile. ARID1A protein levels were significantly lower in the eutopic endometrium of women with endometriosis compared to women without endometriosis. However, an understanding of the physiological effects of ARID1A loss remains quite poor, and the function of Arid1a in the female reproductive tract has remained elusive. In order to understand the role of Arid1a in the uterus, we have generated mice with conditional ablation of Arid1a in the PGR positive cells (Pgrcre/+Arid1af/f; Arid1ad/d). Ovarian function and uterine development of Arid1ad/d mice were normal. However, Arid1ad/d mice were sterile due to defective embryo implantation and decidualization. The epithelial proliferation was significantly increased in Arid1ad/d mice compared to control mice. Enhanced epithelial estrogen activity and reduced epithelial PGR expression, which impedes maturation of the receptive uterus, was observed in Arid1ad/d mice at the peri-implantation period. The microarray analysis revealed that ARID1A represses the genes related to cell cycle and DNA replication. We showed that ARID1A positively regulates Klf15 expression with PGR to inhibit epithelial proliferation at peri-implantation. Our results suggest that Arid1a has a critical role in modulating epithelial proliferation which is a critical requisite for fertility. This finding provides a new signaling pathway for steroid hormone regulation in female reproductive biology and furthers our understanding of the molecular mechanisms that underlie dysregulation of hormonal signaling in human reproductive disorders such as endometriosis.
    Full-text · Article · Sep 2015 · PLoS Genetics
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    ABSTRACT: Objective: Post-contrast T1 values are closely related to the degree of myocardial extracellular space expansion. We determined the relationship between post-contrast T1 values and left ventricular (LV) diastolic function, LV remodeling, and neurohormonal activation in patients with dilated cardiomyopathy (DCM). Materials and methods: Fifty-nine patients with DCM (mean age, 55 ± 15 years; 41 males and 18 females) who underwent both 1.5T magnetic resonance imaging and echocardiography were enrolled. The post-contrast 10-minute T1 value was generated from inversion time scout images obtained using the Look-Locker inversion recovery sequence and a curve-fitting algorithm. The T1 sample volume was obtained from three interventricular septal points, and the mean T1 value was used for analysis. The N-Terminal pro-B-type natriuretic peptide (NT-proBNP) level was measured in 40 patients. Results: The mean LV ejection fraction was 24 ± 9% and the post-T1 value was 254.5 ± 46.4 ms. The post-contrast T1 value was significantly correlated with systolic longitudinal septal velocity (s'), peak late diastolic velocity of the mitral annulus (a'), the diastolic elastance index (Ed, [E/e']/stroke volume), LV mass/volume ratio, LV end-diastolic wall stress, and LV end-systolic wall stress. In a multivariate analysis without NT-proBNP, T1 values were independently correlated with Ed (β = -0.351, p = 0.016) and the LV mass/volume ratio (β = 0.495, p = 0.001). When NT-proBNP was used in the analysis, NT-proBNP was independently correlated with the T1 values (β = -0.339, p = 0.017). Conclusion: Post-contrast T1 is closely related to LV remodeling, diastolic function, and neurohormonal activation in patients with DCM.
    Preview · Article · Sep 2015 · Korean journal of radiology: official journal of the Korean Radiological Society
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    ABSTRACT: This research was conducted to develop effective and safe marine-derived antiviral compounds against norovirus. The ethyl acetate (EtOAc)-extract from Eisenia bicyclis exhibited strong antiviral activity against murine norovirus (MNV) as a norovirus surrogate. Among the phlorotannins from E. bicyclis, dieckol (DE) and phlorofucofuroeckol-A (PFF) were known to possess the strongest antibacterial activity. In this study, DE and PFF were evaluated for antiviral activity against MNV DE and PFF exhibited strong anti-MNV activity with 50% effective concentration (EC50) of 0.9 pM. However, PFF ex­hibited more effective antiviral activity against MNV with higher selective index (668.87) than that of DE (550.60), due to its lower cell toxicity against RAW 264.7. This is the first report on the anti-MNV activity of phlorotannins from seaweed. The results obtained in this study suggest that the phlorotannins could be used as a potential source of natural antiviral agents.
    No preview · Article · Sep 2015
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    ABSTRACT: Adenotonsillar hypertrophy is the most common etiology in pediatric obstructive sleep apnea syndrome (OSAS), and adenotonsillectomy is the mainstay of treatment modalities. This study evaluates the long-term effectiveness of adenotonsillectomy in children with OSAS. Subjective symptoms evaluated with a 7-point Likert scale and objective respiratory disturbances evaluated by polysomnography were compared before and after adenotonsillectomy. A total of 17 children with OSAS aged 4-15 years (mean age, 6.65±3.02 years; male:female, 13:4) completed the study. The mean follow-up period was 57 months (range, 30 to 98 months). Significant changes were found in apnea-hypopnea index (from 12.49±12.96 to 1.96±2.01, P<0.001), apnea index (from 5.64±7.57 to 0.53±0.78, P=0.006), minimum SaO2 (from 81.88±14.36 to 92.76±4.31, P=0.003), snoring (from 43.28±70.63 to 10.70±13.72, P=0.042), and arousal index (from 19.58±7.57 to 11.36±3.99, P=0.006) after adenotonsillectomy. Significant changes were also found after surgery in most of symptoms including snoring, witnessed apnea, morning headache, mouth breathing, gasping during sleep, restless sleep, nasal obstruction, and difficulty with morning arousal. Long-term surgical cure rate and response rate were 47.1% (8/17) and 70.6% (12/17), respectively. Most of subjective OSAS symptoms and objective respiratory disturbances improved continuously about 5 years after adenotonsillectomy in children with OSAS. However, close follow-up and a sufficient observation period are necessary because of the risk for long-term incomplete resolution.
    Preview · Article · Sep 2015 · Clinical and Experimental Otorhinolaryngology
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    ABSTRACT: CCCTC binding factor (CTCF) is involved in organizing chromosomes into mega base-sized, topologically associated domains (TADs) along with other factors that define sub-TAD organization. CTCF-Cohesin interactions have been shown to be critical for transcription insulation activity as it stabilizes long-range interactions to promote proper gene expression. Previous studies suggest that heterochromatin boundary activity of CTCF may be independent of Cohesin, and there may be additional mechanisms for defining topological domains. Here, we show that a boundary site we previously identified known as CTCF binding site 5 (CBS5) from the homeotic gene cluster A (HOXA) locus exhibits robust promoter activity. This promoter activity from the CBS5 boundary element generates a long noncoding RNA that we designate as boundary associated long noncoding RNA-1 (blncRNA1). Functional characterization of this RNA suggests that the transcript stabilizes long-range interactions at the HOXA locus and promotes proper expression of HOXA genes. Additionally, our functional analysis also shows that this RNA is not needed in the stabilization of CTCF-Cohesin interactions however CTCF-Cohesin interactions are critical in the transcription of blncRNA1. Thus, the CTCF-associated boundary element, CBS5, employs both Cohesin and noncoding RNA to establish and maintain topologically associated domains at the HOXA locus.
    Preview · Article · Aug 2015 · PLoS ONE
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    ABSTRACT: This study evaluates myocardial edema by quantitative T2 mapping in patients with acute myocardial infarction (AMI) and compares the lateral extent of myocardial edema with those of infarcted and dysfunctional myocardium. Cardiac magnetic resonance images (MRIs) of 31 patients (M:F=29:2, mean age: 52.5±10.8 years) with AMI were reviewed. On cine-MRI, all short axis images of the left ventricle (LV) were divided into 60 sectors. The regional wall motion of each sector was calculated as follows: systolic wall thickening (SWT,%) = ((LV wall thicknessES - LV wall thicknessED)/LV wall thicknessED)*100. Dysfunctional myocardium was defined as sectors with decreased SWT lower than 40%. On LGE-images, myocardial infarction was defined as an area of hyper-enhancement more than 5 SDs from the remote myocardium. On T2 map, myocardial edema was defined as an area in which T2 values were at least 2 SDs higher than those from remote myocardium. The lateral extents of infarcted myocardium, myocardial edema, and dysfunctional myocardium were calculated as the percentage of central angles ((central angle of the involved myocardium/360)*100 (%)) and then compared. The lateral extent of myocardial edema was slightly larger than that of infarcted myocardium (37.4±13.3% vs. 35±12.9%, p<0.01). The lateral extent of dysfunctional myocardium (50.6±15.3%) was significantly larger than that of infarcted myocardium or myocardial edema (p<0.001). The lateral extent of myocardial edema beyond the infarcted myocardium might be narrow, but the dysfunctional myocardium could be significantly larger than myocardial edema, suggesting stunned myocardium without edema. Copyright © 2015. Published by Elsevier Inc.
    No preview · Article · Aug 2015 · Magnetic Resonance Imaging

  • No preview · Article · Aug 2015 · Clinical Toxicology

Publication Stats

8k Citations
1,235.55 Total Impact Points


  • 2009-2016
    • Inje University
      • Department of Nano Engineering
      Kŭmhae, Gyeongsangnam-do, South Korea
    • Pukyong National University
      Tsau-liang-hai, Busan, South Korea
  • 2015
    • Korea Polar Research Institute
      Sŏul, Seoul, South Korea
    • University of California, San Diego
      San Diego, California, United States
    • Daegu University
      Daikyū, Daegu, South Korea
    • Chonbuk National University
      • College of Veterinary Medicine
      Tsiuentcheou, Jeollabuk-do, South Korea
    • Korea Institute of Radiological & Medical Sciences
      Sŏul, Seoul, South Korea
  • 2014-2015
    • University of Texas at Dallas
      Richardson, Texas, United States
    • Stockton University
      Эгг Харбор Сити, New Jersey, United States
    • Dong-Eui University
      Busan, Busan, South Korea
    • Gangneung Asan Hospital
      Sŏul, Seoul, South Korea
    • Dong-A University
      Tsau-liang-hai, Busan, South Korea
    • Seoul National University Hospital
      • Department of Plastic and Reconstructive Surgery
      Sŏul, Seoul, South Korea
    • Daegu Fatima Hospital
      연천군, South Korea
    • Busan National University of Education
      Busan, Busan, South Korea
  • 2012-2015
    • Michigan State University
      • Department of Obstetrics, Gynecology, and Reproductive Biology
      Ист-Лансинг, Michigan, United States
    • National Cancer Center Korea
      • Specific Organs Cancer Branch
      Kōyō, Gyeonggi-do, South Korea
  • 2009-2015
    • Daegu Haany University
      Daikyū, Daegu, South Korea
  • 2004-2015
    • Yonsei University Hospital
      • Department of Internal Medicine
      Sŏul, Seoul, South Korea
    • Yonsei University
      • • Department of Radiology
      • • Natural Science Research Institute
      Sŏul, Seoul, South Korea
    • Korea Atomic Energy Research Institute (KAERI)
      • Advanced Radiation Technology Institute
      Daiden, Daejeon, South Korea
  • 2002-2015
    • Sejong General Hospital
      Bucheon, Gyeonggi-do, South Korea
  • 1999-2015
    • Korea University
      • • College of Medicine
      • • Department of Chemistry
      Sŏul, Seoul, South Korea
  • 2013-2014
    • Kyungnam University
      Changnyeong, Gyeongsangnam-do, South Korea
    • Dankook University
      • Department of Chemical Engineering
      Eidō, Chungcheongbuk-do, South Korea
    • LG Life Sciences
      Sŏul, Seoul, South Korea
    • Daewoo Engineering and Construction
      Sŏul, Seoul, South Korea
  • 2011-2014
    • Sahmyook University
      Sŏul, Seoul, South Korea
    • International St. Mary's Hospitals
      Chemulpo, Incheon, South Korea
    • Catholic University of Korea
      Sŏul, Seoul, South Korea
  • 2009-2014
    • Yale University
      • Department of Genetics
      New Haven, Connecticut, United States
  • 2006-2014
    • Korea Advanced Institute of Science and Technology
      • • Graduate School of Medical Science and Engineering
      • • Department of Physics
      • • Department of Aerospace Engineering
      • • Department of Mechanical Engineering
      Sŏul, Seoul, South Korea
    • Electronics and Telecommunications Research Institute
      Sŏul, Seoul, South Korea
  • 2001-2014
    • Pusan National University
      • • Department of Horticultural Bioscience
      • • Department of Molecular Biology
      • • Division of Electrical and Electronics Engineering
      • • Department of Physics
      Tsau-liang-hai, Busan, South Korea
    • University of Minnesota Duluth
      Duluth, Minnesota, United States
  • 2009-2013
    • Korea Institute of Machinery and Materials
      Sŏul, Seoul, South Korea
    • Northeastern University
      • Department of Mechanical and Industrial Engineering
      Boston, Massachusetts, United States
  • 2007-2013
    • Wonju Severance Christian Hospital
      Genshū, Gangwon, South Korea
    • Yale-New Haven Hospital
      New Haven, Connecticut, United States
    • Dongseo University
      • Department of Systems and Management Engineering
      Tsau-liang-hai, Busan, South Korea
  • 2006-2013
    • Sungkyunkwan University
      • School of Advanced Materials Science and Engineering (AMSE)
      Sŏul, Seoul, South Korea
  • 2005-2013
    • Seoul National University
      • • Department of Electrical and Computer Engineering
      • • Department of Earth and Environmental Sciences
      • • Department of Materials Science and Engineering
      Sŏul, Seoul, South Korea
    • Ludwig Institute for Cancer Research
      La Jolla, California, United States
    • The Australian Society of Otolaryngology Head & Neck Surgery
      Evans Head, New South Wales, Australia
  • 2011-2012
    • University of Maryland, College Park
      • Department of Mechanical Engineering
      CGS, Maryland, United States
    • Yeungnam University
      • College of Pharmacy
      Onyang, South Chungcheong, South Korea
    • University of Ulsan
      • Department of Surgery
      Ulsan, Ulsan, South Korea
  • 2010-2012
    • Kyungpook National University
      • • School of Medicine
      • • Mobile Display Research Center
      Daikyū, Daegu, South Korea
    • Soonchunhyang University
      Onyang, Chungcheongnam-do, South Korea
  • 2009-2012
    • Baylor College of Medicine
      • Department of Molecular & Cellular Biology
      Houston, Texas, United States
  • 2010-2011
    • Inje University Paik Hospital
      • Department of Internal Medicine
      Sŏul, Seoul, South Korea
  • 2009-2011
    • The Ohio State University
      • Department of Psychology
      Columbus, Ohio, United States
  • 2005-2010
    • Chung-Ang University
      • College of Medicine
      Sŏul, Seoul, South Korea
  • 2001-2010
    • Korea Research Institute of Chemical Technology
      Daiden, Daejeon, South Korea
  • 2008
    • Gyeongsang National University
      • School of Materials Science and Engineering
      Chinju, South Gyeongsang, South Korea
    • Changwon National University
      Changnyeong, South Gyeongsang, South Korea
  • 2007-2008
    • Kunsan National University
      • Department of Oceanography
      Gunzan, North Jeolla, South Korea
  • 2006-2008
    • Samsung Electro-Mechanics
      Sŏul, Seoul, South Korea
  • 1999-2008
    • Fairchild Semiconductor
      San José, California, United States
  • 2006-2007
    • Chungnam National University
      • Department of Advanced Organic Materials and Textile System Engineering
      Daiden, Daejeon, South Korea
  • 2005-2006
    • Okayama University
      • Faculty of Pharmaceutical Science
      Okayama, Okayama, Japan
  • 1999-2005
    • Pohang University of Science and Technology
      • • Department of Chemistry
      • • Department of Electronic and Electrical Engineering
      Geijitsu, Gyeongsangbuk-do, South Korea
  • 2002-2004
    • Korea Photonics Technology Institute
      Sŏul, Seoul, South Korea
  • 2003
    • Kyung Hee University Medical Center
      Sŏul, Seoul, South Korea
  • 2000-2002
    • Sejong Institute
      Sŏngnam, Gyeonggi-do, South Korea