- [Show abstract] [Hide abstract] ABSTRACT: A case of primary leptomeningeal malignant melanoma localized in the cervical region in a 41-year-old woman is presented. The only clinical finding was intracranial hypertension with papilledema. A diagnosis of primary CNS melanoma was made after dermatological and ophthalmological consultations, ruled out a metastatic lesion. Primary leptomeningeal melanoma is an extremely rare spinal tumor. Its clinical presentation with signs of increased intracranial pressure but without cord symptoms is unusual. Clinical features of this case including the radiological and histologic findings are described. Diagnosis as well as management are discussed.
- [Show abstract] [Hide abstract] ABSTRACT: Although the human brain makes up only 2 per cent of total body weight, it receives 15 to 20 per cent of cardiac output and accounts for 20 per cent of total body oxygen consumption under normal conditions. Cessation of blood flow results in rapid depletion of energy reserves which can produce ischemic neurological symptoms within seconds. In this paper the authors describe in details the arterial and venous part of the brain circulation as well as the clinical signs and symptoms in the cases with ischemia in them feeding areas.