M Pfeiffer

Universität Ulm, Ulm, Baden-Württemberg, Germany

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Publications (7)5.4 Total impact

  • V. Kächele · M. Wabitsch · B. Hay · M.M. Pfeiffer · G. Adler · W. Kratzer
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    ABSTRACT: Objective. To assess the prevalence of and risk factors (e. g., obesity and positive family history) for the development of cholecystolithiasis in a non-selected collective of children and adolescents. Design and participants. A series of 482 children and adolescents aged 6–18 years underwent upper abdominal diagnostic ultrasound examinations as part of a whole-community investigation (response rate: 78%) for Echinococcus multilocularis in a town in southern Germany. Results. Gallbladder stones were identified in three of 482 children, corresponding to a prevalence of 0.6%. None of the three children was overweight at the time of the examination. Additional risk factors (pronounced weight reduction and Wilson's disease) were present in one study subject. Conclusions. Findings of the present study do not confirm the significance of obesity as a risk factor for cholecystolithiasis in children and adolescents.
    No preview · Article · Apr 2012 · Monatsschrift Kinderheilkunde
  • W Kratzer · M Pfeiffer · M Gebel · C Dietrich · G Adler
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    ABSTRACT: Objective of the present study is to provide a current overview of the present state of research in abdominal ultrasound in the gastroenterological departments of university hospitals in Germany. We conducted a survey assessing the number of research projects in progress, sources of financial support, sponsorship by the private sector and publications generated. Reports from 28 of 35 gastroenterological departments responding to the survey indicated that a total of 124 research projects were in progress during the survey period, for an average of 3.5 projects per department. Clinical issues were addressed in 78 studies, technical questions in 33 studies and other questions in 13 studies. Of the 117 publications generated, 50 appeared in German-language journals and 67 in English-language journals. At present, neither the German Research Association (DFG) or the European Union (EU) is financially underwriting an ultrasound research project in the gastroenterological department of any German university hospital. Ultrasound remains the most frequently applied diagnostic imaging technique in gastroenterology. In order to convert the enormous technological progress into improved diagnostic capabilities, there must be a significant expansion in research support for gastrointestinal ultrasound.
    No preview · Article · Nov 2000 · Zeitschrift für Gastroenterologie
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    ABSTRACT: Objective of the present study was the comparison of various administration forms of the ultrasound contrast medium Levovist with regard to duration and intensity of contrast enhancement in patients with tumors of the liver or pancreas. Seven patients with tumors of the liver or pancreas were examined prospectively using power Doppler sonography. Ultrasound contrast enhancement was achieved using Levovist (8 ml, 400 mg/ml) in three different administration forms: 1st as a bolus injection through the main channel, 2nd through the injection valve of an intravenous cannula, or 3rd as a continuous infusion. Semiquantitative evaluation of the degree of contrast enhancement over the course of the examination was conducted by three independent examiners. Levovist, administered by continuous infusion, resulted in a significantly longer average period of contrast enhancement (9:43 min (extratumoral), 7:34 min (intratumoral)) than did the same dosage administered as a bolus injection through the main channel (6:01 min (extratumoral), 4:54 min (intratumoral), p = 0.0156 (extratumoral); p = 0.0313 (intratumoral), but contrast intensity was decreased. Bolus injection through the injection valve of the i.v. cannula was associated with decreased duration and intensity of contrast enhancement compared with injection through the main channel. Compared with bolus injection, the continuous infusion of Levovist resulted in a significant prolongation of the duration but in a decreased intensity of contrast enhancement. Administration of Levovist through the injection valve does not result in optimal contrast enhancement and is therefore not recommended.
    No preview · Article · Jun 2000 · RöFo - Fortschritte auf dem Gebiet der R
  • W Kratzer · M Pfeiffer · G Adler

    No preview · Article · Feb 2000 · Der Internist
  • W Kratzer · M Pfeiffer · M Gebel · C Dietrich · G Adler

    No preview · Article · Jan 2000 · Zeitschrift für Gastroenterologie
  • W Kratzer · M Kron · B Hay · M M Pfeiffer · V Kächele
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    ABSTRACT: Gallbladder stones represent one of the most common reason for morbidity in western industrial nations. There remains a paucity of exact information regarding the prevalence and risk factors for this disease entity in Germany. As part of a whole-community survey focusing on the prevalence of echinococcosis multilocularis conducted in a population in southwestern Germany (response rate: 66.6%), 2,560 subjects underwent an upper abdominal ultrasound examination at which the presence of gallbladder stones was ascertained. In each case, upper abdominal sonography was performed following completion of a standardized interview. In 62 subjects, the gallbladder could not be adequately visualized due to an insufficient fasting period; the remaining 2,498 subjects (1,326 females, age 38.9 +/- 19.9 years; 1,172 males, age 37.7 +/- 18.8 years) were included in the study collective. Gallbladder stones (sonographically visualized gallbladder stones or history of cholecystectomy for cholecystolithiasis) were found in 196 participants (7.8%; 139 females [10.5%] versus 57 males [4.9%]). Statistical treatment of the data using multiple logistical regression techniques revealed a significant influence of the variables age, gender, body mass index (BMI) and positive family history on the development of gallbladder stones. The prevalence of gallbladder stones in the present study population is lower than figures reported for a study in Brandenburg and at 7.8% is rather low in comparison with other European studies. One explanation may be the low average age of study participants, almost 50% of whom were less than 35 years. Besides age, subjects' gender, BMI and positive family history were identified as significant risk factors.
    No preview · Article · Jan 2000 · Zeitschrift für Gastroenterologie
  • W. Kratzer · M. Pfeiffer · G. Adler
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    ABSTRACT: Die Qualitätssicherung sowie die Verbesserung der Ausbildungssituation im Bereich der Abdomensonographie ist eine kontinuierliche und nachhaltige Herausforderung. Ziel der hier dargestellten Untersuchung war es, die Ausbildungssituation und die Qualitätssicherungsmaßnahmen an den deutschen Universitätskliniken für Ärztinnen und Ärzte in den Abteilungen für Gastroenterologie sowie das Lehrangebot für Studierende zu untersuchen. Im Rahmen einer Umfrage an den deutschen Universitätskliniken wurde nach den durchführenden Abteilungen der Abdomensonographie, Anzahl der Untersuchungen, Geräteausstattung, Ausbildungssituation, Qualitätssicherung im Bereich der Routinediagnostik und Lehrangeboten für Studierende im Bereich Ultraschall gefragt.
    No preview · Article · Dec 1999 · Der Internist