M.S. Kim

University of Ulsan, Urusan, Ulsan, South Korea

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Publications (21)4.42 Total impact

  • S.W. Kim · M.W. Lee · M.S. Kim · T.Y. Han · J.H. Lee · S.-J. Son
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    ABSTRACT: Subepidermal calcified nodule is an unusual type of idiopathic calcinosis cutis and usually presents as an asymptomatic, solitary, firm, verrucous, white or yellowish nodule. It commonly occurs in young children, generally on the face and neck, especially eyelid, cheek. However, sole is a very rare site. Four patients presented with several months' history of solitary 2 ∼ 3 mm sized firm nodule on the sole. Three of the patients were less than 1 year old, with no history of trauma. Histopathologic examination revealed hyperkeratosis, acanthosis and amorphous basophilic material in cystic space beneath the epidermis, meaning deposition of calcium salt. These histopathologic features were consistent with subepidermal calcified nodule. Serum calcium and phosphorus levels of the patients were within normal limits. Herein, we present 4 cases of subepidermal calcified nodule on the sole, an atypical location.
    No preview · Article · Feb 2013 · Korean Journal of Dermatology
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    ABSTRACT: Background: Because cosmetic laser treatments are getting popular, post-laser wound care becomes more important. Currently, topical moisturizers are reported to be sufficient to accelerate re-epidielialization and reduce downtime in post-laser wound care. Objective: This study was performed to evaluate the effects of the moisturizer APDDR-1001 for post-laser wound care, after ablative fractional laser on the face. Methods: In this double-blind, split-face study, 41 patients with photo-aged face received ablative fractional laser. They were divided into two groups, APDDR-1001 and vehicle (group 1) or control moisturizer (group 2), which were applied to the opposite sides of the face for 1 week after the laser treatment. The treatment efficacy was evaluated by the transepidermal water loss (TEWL), erythema index, investigator's assessment for recovery in erythema and overall improvement of the wound. Subjects ranked irritating symptoms and overall satisfaction ratings in the overall improvement. Results: APDDR-1001 was well-tolerated and showed improvement in the erythema index and TEWL during the 7 days of treatment. In group 2, improvement in erythema graded by investigators was significantly higher for APDDR-1001 on day 3 (p<0.05). The overall improvement of wound ranked by investigators was significantly higher for APDDR-1001, compared with the controls in both groups. Subjective assessment demonstrated significantly less erythema (p=0.043), edema (p=0.041) and overall satisfaction ratings in the overall improvement (p < 0.048) with APDDR-1001; however, no differences were detected in pain and edema between APDDR-1001 and vehicle (group 1). In group 2, subjects ranked 'much or very much improved' in 75 % of APDDR-1001 side and 55% of control moisturizer side. No significant differences in erythema, edema, pain and itching were reported between APDDR-1001 and control moisturizer in group 2. Conclusion: The moisturizer APDDR-1001 demonstrated effective improvements in wound healing and subjective symptoms after ablative fractional laser therapy.
    No preview · Article · Dec 2012 · Korean Journal of Dermatology
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    ABSTRACT: Background: Paronychia is a common infectious disease affecting fingernails and toenails. Although bacterial and fungal infections as well as mechanical trauma may play roles in the pathogenesis of this disease, there are few bacteriological studies about paronychia in military personnel. Objective: To identify the causative bacteria of paronychia in military personnel. Methods: We retrospectively analyzed the microbiological results of 145 patients who visited a tertiary referral hospital for Korean soldiers from August 2004 to October 2006. Results: Twenty-eight different types of aerobic bacteria were identified, with the most common being Staphylococcus aureus (38.0%), Streptococcus pyogenes (7.2%), and Pseudomonas aeruginosa (5.4%). Staphylococcus aureus was identified mostly in finger and toe paronychial lesions and Pseudomonas aeruginosa was recovered commonly from toe paronychial lesions. All cases of paronychia were controlled by the combination of antiseptic dressing, topical antibacterial ointment, oral antibiotics, and antimycotic agents. Conclusion: The types of bacteria that most commonly caused paronychia in military personnel were Staphylococcus aureus, Staphylococcus pyogenes, and Pseudomonas aeruginosa. Thus, the commonly used oral antibiotics for paronychia, such as amoxicillin-clavulanate, clindamycin, and trimethoprim- sulfamethoxazole, are good choices in the treatment of paronychia in military personnel.
    No preview · Article · Sep 2012 · Korean Journal of Medical Mycology
  • M S Kim · S M Lee · H S Sung · C H Won · S Chang · M W Lee · J-H Choi · K-C Moon
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    ABSTRACT: Deep cutaneous mycoses can cause significant morbidity and mortality, especially in immunocompromised patients. There have been few studies focusing on deep cutaneous mycoses and there are no data from Asian countries. This study aimed to investigate clinical characteristics, underlying predisposing factors, aetiological organisms and outcomes in patients with deep cutaneous mycoses. A retrospective medical record review of patients with deep cutaneous mycoses treated at a tertiary referral centre in Korea from 1999 to 2010. Forty-one cases of deep cutaneous mycosis were identified (median age: 49). Most patients (32/41) had impaired immunological status, and seven of the remaining nine had a history of physical trauma. Neutropenia and long-term use of antibiotics were detected in 13 and 12 patients respectively. Nodular skin lesions were the most common type (17/41) and the morphology of the lesions varied. Fungal organisms were identified by culture and histopathology of skin specimens. Candida (16/41) was the most common organism, followed by Aspergillus, Alternaria, Fusarium (4/41 each). Systemic antifungal treatment was successful in 28 patients, while nine patients died from the fungal infection. Our study may lead to improved insights into deep cutaneous mycoses as their incidence is increasing and they vary in different clinical settings.
    No preview · Article · Apr 2012 · Mycoses
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    ABSTRACT: Muir-Torre syndrome is defined by concurrent or sequential development of internal malignancy - most commonly colorectal cancer - and sebaceous neoplasm or multiple keratoacanthomas. Recent studies revealed it was caused by mutations in DNA mismatch repair genes, and suggested screening for mismatch repair gene defects may be of value for patients with Muir-Torre syndrome. We, herein, report a patient with Muir-Torre syndrome, who developed breast cancer and extra-ocular sebaceous carcinoma. In addition, we discussed our experience of immunohistochemical staining for mismatch repair protein with a review of the literature.
    No preview · Article · Aug 2010 · Korean Journal of Dermatology
  • M.S. Kim · T.Y. Han · J.H. Lee · S.J. Son
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    ABSTRACT: Dermatofibrosarcoma protuberans (DFSP) is a tumor of intermediate malignancy that has long been considered to almost exclusively affect adults. Congenital DFSP is extremely rare and the diagnosis is often difficult because of the deceptive appearance of the lesions. A 12-month-old infant developed an asymptomatic red indurated nodule on the lower aspect of his back. The brownish macule had appeared at birth and the lesion grew rapidly 6 months later. Histologic examination showed spindle shaped cells with a storiform pattern and the cells were positive for CD34 stain. A diagnosis of congenital DFSP was made and the mass was removed by wide local excision. There was no evidence of recurrence at follow-up 8 months later.
    No preview · Article · Jul 2010 · Korean Journal of Dermatology
  • H. Lee · M.S. Kim · T.Y. Han · J.H. Lee · S.-J. Son
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    ABSTRACT: Cutaneous larva migrans is a characteristic serpiginous creeping eruption that is caused by the migration of the larval form of neomatodes in the skin. It is caused by hookworm larvae, which are present in the feces of infected dogs and cats. The skin lesions progressively evolve at a rate of 2-3 cm daily. Most cases have a travel history to tropical and subtropical countries, but our patient had no travel history to an endemic area and no contact history with the feces of dogs and cats. We report herein on a case of cutaneous larva migrans on the neck and the patient did not have a travel history to an endemic area and the lesions showed relatively rapid progression.
    No preview · Article · Jun 2010 · Korean Journal of Dermatology
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    ABSTRACT: Background: Cutaneous metastasis from an internal malignancy is uncommon and it usually arises from the breast and lung. Cutaneous metastasis from gastric cancer is rarely seen, although gastric cancer is the most common internal cancer in Korea. Objective: The purpose of this study was to analyze the clinical and histopathological characteristics of cutaneous metastasis from gastric cancer in Korea. Methods: Twenty-seven cases of cutaneous metastasis from gastric cancer were included in the study among the 14,053 patients who were diagnosed with gastric adenocarcinoma over a 20 year period. Their medical records and pathology slides were retrospectively reviewed. Results: The incidence of cutaneous metastasis was 0.19% (27/14,053). The age of the 27 patients ranged from 28 to 75, and the mean age was 53.9 with no significant difference in gender. The most frequently involved site was the abdomen followed by the face and scalp. Nodular lesion was most common (55.6%, 17/27) and inflammatory and indurated lesions were 25.9% (7/27) and 7.4% (2/27), respectively. Histopathologically, poorly differentiated adenocarcinoma (13/27) and signet-ring cell carcinoma (10/27) were common, which comprised 85.1% of the total tumor. In 7 cases (25.9%), skin lesion was the first presenting sign of gastric cancer or metastatic gastric cancer. The mean survival of the patients was 4.7 months. Conclusion: Cutaneous metastasis from gastric cancer is rare despite gastric cancer's high prevalence as a primary cancer in Korea. It was frequently observed in patients with an advanced disease stage, yet it may represent the initial manifestation of the disease. Dermatologists can contribute to the management of patients with cutaneous metastasis by performing early detection and recognition of skin lesions.
    No preview · Article · May 2010
  • H. Lee · M.S. Kim · J.H. Lee · K. Park · S.-J. Son
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    ABSTRACT: Skin cancers require excision and reconstruction for achieving optimal functional and cosmetic results. There are numerous reconstructive options, which include primary repair, secondary intention healing, a local flap and a skin graft. Generally, a full-thickness skin graft is not considered applicable for reconstructing a nasal defect because a local flap is thought to be a superior alternative to a skin graft due to the unique nature of the lower third of the skin, which is often thick and fixed to the adjacent structures. But a defect on a lower third of the nose that includes the nasal ala can be well reconstructed by a skin graft in some cases. The donor site options include the preauricular, postauricular and supraclavicular areas etc. But in some cases, the forehead skin is a good match with the nasal ala area. We herein report the case of a 69-year-old female with a nasal ala defect that was induced by excision of basal cell carcinoma. The patient was reconstructed with a full-thickness skin graft using the redundant skin of the forehead.
    No preview · Article · Jan 2010 · Korean Journal of Dermatology
  • M.S. Kim · J.H. Lee · K. Park · S.-J. Son
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    ABSTRACT: The risk of pressure sores is greatest in patients who are elderly, debilitated, incontinent, paralyzed or unconscious. During surgery, patients are immobile and they are unable to perceive the discomfort of prolonged pressure, and the anesthetized patient lacks a protective mechanism to prevent pressure sores. We report here on the case of a 6-year-old boy who presented with a pressure sore of the contralateral helical rim after middle ear surgery. Despite 10 days of treatment, the dermatological examination showed skin necrosis over the helical rim. He required debridement of the skin and the defect was subsequently reconstructed with a split-thickness skin graft.
    No preview · Article · Dec 2009
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    ABSTRACT: A 68-year-old woman presented with a solitary dome-shaped papule on the right forth finger and this lesion had been developing for the past 4 months. Histopathologic examination revealed the dermal infiltration of histiocytes with foam cells and Touton-type multinucleated giant cells, which was compatible with the diagnosis of xanthogranuloma. Based on the previous reports, xanthogranuloma of the finger is quite rare, and especially in adults. Herein, we report on a case of xanthogranuloma arising on the finger of an adult.
    No preview · Article · Nov 2009 · Korean Journal of Dermatology
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    ABSTRACT: Stenotrophomonas maltophiliais a nonfermentative Gram-negative bacillus, and this is an emerging pathogen for nosocomial infection. It is commonly associated with pneumonia and catheter-related bacteremia, and especially in immunocompromised patients. Cutaneous infection with Stenotrophomonas maltophilia is uncommon, yet it may cause therapeutic problems because of its intrinsic resistance to common antibiotics and the immunodeficiency of the affected host. Herein, we report on a case of metastatic cellulitis secondary to Stenotrophomonas maltophilia bacteremia, and this developed in an immunocompromised patient. He was successfully treated with intravenous trimethoprim-sulfamethoxazole.
    No preview · Article · Aug 2009 · Korean Journal of Dermatology
  • W J Lee · M S Kim · S E Chang · M W Lee · J H Choi · K C Moon · J K Koh
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    ABSTRACT: The most common metastatic sites of cholangiocarcinoma are the retroperitoneal lymph nodes, peritoneum, liver and lungs, and cutaneous metastases of cholangiocarcinoma are rare. Although cutaneous metastases of internal malignancies most commonly present clinically as nontender nodules appearing in a particular area of body, other presentations can occur. Cutaneous metastases of cholangiocarcinoma can appear as a solitary tumour at the therapeutic drainage site. We report a 60-year-old man with unusual cutaneous metastases from hilar cholangiocarcinoma, which presented as multiple indurated plaques and papules on the anterior chest.
    No preview · Article · Jul 2009 · Clinical and Experimental Dermatology
  • W J Lee · M S Kim · M W Lee · J H Choi · K C Moon · J K Koh

    No preview · Article · Jun 2009 · Clinical and Experimental Dermatology
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    ABSTRACT: Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma (CSMTCL) is a rare disease constituting 2% of all cutaneous T-cell lymphomas. In most cases, CSMTCL occurs as a solitary lesion and has an indolent course. Here we present a 42-year-old woman with multiple, localized, recurrent, erythematous papules and macules that developed after combination chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP).
    No preview · Article · Mar 2009 · Korean Journal of Dermatology
  • M.S. Kim · H.-S. Moon · K. Park · J.E. Joo · S.-J. Son
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    ABSTRACT: Superficial epithelioma with sebaceous differentiation (SESD) is a histologically distinct, rare, benign neoplasm characterized by a superficial plate-like proliferation of basaloid cells with broad attachments to the overlying epidermis. Clusters of sebaceous cells were present within the lobules. We herein report a case of SESD in a 73-year-old female.
    No preview · Article · Feb 2009 · Korean Journal of Dermatology
  • W.J. Lee · M.S. Kim · S.M. Kang · M.W. Lee · J.H. Choi · K.C. Moon · J.K. Koh
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    ABSTRACT: Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Histopathologically, Ewing's sarcoma consists of solid sheets of small round cells with vesicular nuclei and scant cytoplasm, and the cells are arranged in irregular masses separated by strands of fibrous tissue. Extraskeletal Ewing's sarcoma may arise virtually anywhere, but it is most common in the deep soft tissues of the extremities. We report here on a 27-year-old woman with cutaneous extraskeletal Ewing's sarcoma. She presented with a subcutaneous tumor of the right upper arm, and this was without osseous involvement. The patient underwent wide local excision and she received chemotherapy with vincristine, cyclophosphamide, etoposide and ifosfamide. There has been no evidence of recurrence or metastasis during 16 months of follow up. (Korean J Dermatol 2008;46(10):1427-1431).
    No preview · Article · Oct 2008 · Korean Journal of Dermatology
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    ABSTRACT: Although a basal cell carcinoma usually results from chronic irradiation of solar ultraviolet, some reports have mentioned that non-solar ultraviolet and trauma also could be etiologic factors of basal cell carcinoma. Herein, we report a case of a 64-year-old man who had worked as a welder for more than thirty years. Four years ago, he was burnt on his right upper eyelid during welding. After that, the lesion had been darkened and indurated, and finally was diagnosed as basal cell carcinoma. The significance of non-solar ultraviolet irradiation and thermal burn during welding in the pathogenesis of basal cell carcinoma is discussed.
    No preview · Article · Aug 2008 · Korean Journal of Dermatology
  • M.S. Kim · H.-S. Lee · K. Park · S.-J. Son
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    ABSTRACT: Spiny keratoderma is a dermatosis consisting of multiple projections located on the palms and soles with a distinct histology characteristic of a parakeratotic column. This disease has been associated with various underlying benign or malignant diseases. We report a case of a 72-year-old female patient with spiny keratoderma associated with diabetes mellitus and hypothyroidism.
    No preview · Article · Apr 2008 · Korean Journal of Dermatology
  • H.J. Lee · M.S. Kim · S.E. Chang · M.W. Lee · J.H. Choi · K.C. Moon
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    ABSTRACT: Coma-induced bullae and sweat gland necrosis is a rare clinicopathologic entity often associated with alcohol intake or drug abuse (barbiturate and benzodiazepine overdose). Local pressure and hypoxia are considered to be important causative factors. But, the exact pathogenesis remains unknown. Herein, we report a case with clinical and histologic findings characteristic of blisters and sweat gland necrosis occurring in a drug-induced comatose patient.
    No preview · Article · Apr 2008 · Korean Journal of Dermatology