[Show abstract][Hide abstract] ABSTRACT: A 41-year-old man was admitted to our hospital with pyrexia up to 40°C. Chest X-ray film showed infiltration of the right lower lung field. As the urine sample was positive for the Legionella antigen, the therapy of LVFX, MINO and RFP administration was started. Although his general condition improved, renal function has gradually deteriorated without an increase in CPK level. Renal biopsy revealed an infiltration of neutrophils into renal tissues. Finally, the patient recovered from renal dysfunction without induction of hemodialysis. We suppose that early diagnosis might lead to proper chemotherapy. Histological findings of this case suggest that in Legionella pneumonia case several factors including dehydration, shock, endotoxemia, NSAIDs administration and direct microbial toxicity could cause renal dysfunction.
No preview · Article · Aug 2008 · Kokyu to junkan. Respiration & circulation
[Show abstract][Hide abstract] ABSTRACT: A 66-year-old female complained of cough, and was referred to our hospital. Chest radiography and computed tomography (CT) showed a tumor mass near the right hilum and atelectasis of the middle lobe. Bronchoscopy revealed a whitish polypoid tumor obstructing the middle lobe bronchus. Histology by punch biopsy suggested adenocarcinoma Right upper and middle lobectomy was performed, due to the direct invasion of the tumor from the middle lobe to the upper lobe. Histological findings showed adenocarcinoma comprised of spindle cell component, finally diagnosing as pleomorphic carcinoma of the lung. After the operation, systemic chemotherapy, including paclitaxel and carboplatin was performed. About 42 months after operation, the patient died of multiple brain metastases.
No preview · Article · Jul 2008 · Kyobu geka. The Japanese journal of thoracic surgery