[Show abstract][Hide abstract] ABSTRACT: The carpometacarpal boss is a bone prominence involving the second and third Carpometacarpal joints. We report a symptomatic case with carpometacarpal boss in 2 female patients aged 22 years old. One was located at the dorsal side between the trapezoid and base of the second metacarpal bone. The other was between the capitate and third metacarpal bone. The localized bony prominence including the bone, joint and synovium was excised. Histologically, degenerative arthritis was revealed in both cases. Pain on motion and pain on grasping completely disappeared after 13 years in one case and 7 months in the other after surgery respectively.
[Show abstract][Hide abstract] ABSTRACT: The clonal chromosomal rearrangement t(11;22) has been reported by karyotypic analysis to be specific for Ewing's sarcoma of bone and soft tissue origin as well as primitive neuroectodermal tumour. In this report, immunohistological analysis of MIC 2 expression and fluorescence in situ hybridization (FISH) were performed using paraffin-embedded tissues. We examined t(11;22) in the nuclei isolated from two Ewing's sarcomas, four primitive neuroectodermal tumours, and three neuroblastomas, which served as negative controls by FISH with an alpha-satellite DNA probe for chromosome 11, a chromosome 22 marker probe, and whole chromosome painting probes for both chromosomes 11 and 22. Both cases of Ewing's sarcoma and the four primitive neuroectodermal tumour specimens were immunoreactive for MIC 2. Both Ewing's sarcomas and three of the four primitive neuroectodermal tumours contained the tumour-specific t(11;22), but the three neuroblastomas did not show this translocation. Based on the cytogenetic results and on the immunohistological investigation of MIC 2 expression, Ewing's sarcoma is suggested to be related closely to primitive neuroectodermal tumour. FISH is a useful aid in determining the tumour type of Ewing's sarcoma and putative related tumours.
No preview · Article · Jan 1997 · The Journal of Pathology
[Show abstract][Hide abstract] ABSTRACT: We examined the effect and assessment of neoadjuvant chemotherapy for 21 spindle cell soft tissue sarcomas treated at our institute from 1982 to 1994. Evaluation of effectiveness of the preoperative chemotherapy was performed by thermogram, 67Ga citrate scintigram, CT scanning and angiogram, and the tumor necrotic rate (≥40%).The 5-year overall survival rate was 69.3%, and the histological assessment according to the tumor necrotic rate mainly corresponded to the prognosis of these patients in comparison with the graphical assessment. Graphical assessment which agrees with histological assessment may be useful for valuating chemotherapeutic efficacy.
[Show abstract][Hide abstract] ABSTRACT: We treated 23 patients with small round cell sarcomas of bone and soft tissue from 1968-1992. All patients were treated with adjuvant chemotherapy and 14 (60.9%) also received radiotherapy. Six of 20 patients who received surgery, had local recurrences within one year. In this series, small round cell sarcomas occurred predominantly in the trunk (47.8%). Prognosis was evaluated by length of survival. The overall survival rate of small round cell sarcomas of soft tissue (15.6%) was significantly lower than that of other high grade sarcomas.
[Show abstract][Hide abstract] ABSTRACT: We treated five cases of open fracture of the ankle part with soft tissue damage between 1980 and 1986.All cases had trouble with the circulation of the blood, therefore, three cases were treated with anastomoses of the blood vessels and four cases with skin grafts.After injury, scrubbing, washing and débridement are absolutely necessary.We do anastomoses of the blood vessels actively by microsurgery, and do free composite grafts of skin and fat for skin defect. This method preserves subcutaneous vascular network and is very useful for skin graft over the joint, because the graft skin develops no contracture nor wrinkling.Furthermore, we apply intermittent compression with milking cuff to make adaptation to the recipient bed successful.
[Show abstract][Hide abstract] ABSTRACT: We analyzed the effectiveness of preoperative chemotherapy mainly with radiographic images in 9 patients with osteosarcoma, 5 patients with other malignant bone tumor and 14 patients with malignant soft tissue tumor. Judging from the application of preoperative to postoperative chemotherapy and outcome, its evaluation was useful in osteosarcoma and malignant soft tissue tumors. Changes in radiographic images by preoperative chemotherapy were the same in malignant bone and soft tissue tumors, but the reactivity of the latter was more evident. In malignant bone and soft tissue tumors, the effects of preoperative chemotherapy should be evaluated for the cases with resection of primary tumor. Malignant bone tumors excepting osteosarcoma also should be assessed through further accumulation of many more cases.
No preview · Article · May 1989 · Gan to kagaku ryoho. Cancer & chemotherapy
[Show abstract][Hide abstract] ABSTRACT: The aneurysm of the extremities is rare. We treated three cases of aneurysm of the extremities. Two cases were diagnosed as true aneurysm and the other case as pseudo-aneurysm. The tumorous masses were non-pulsatile and we did not hear the vascular murmur in these masses. Angiogram showed no pooling image, and they were not dixghosed as soft tissue tumor by the needle biopsy and the open biopsy. The extirpations were performed. Pathological diagnoses were aneurysm, Wehn we fnd the mass of the extremities, should never forget aneurysm as a differential diagnosis.