Kenichi Ando

Gifu University, Gihu, Gifu, Japan

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Publications (14)3.08 Total impact

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    ABSTRACT: Bleeding from parathyroid cysts is rare. The retropharyngeal space has a very soft structure and if bleeding spreads to this space, airway obstruction can easily occur. We report on a 50-year-old female case with idiopathic neck bleeding from a left parathyroid cyst without any episode of injury. The patient complained of neck swelling after exercise and went to a nearby hospital. At the hospital, the doctor thought this swelling was caused by retropharyngeal bleeding from a tumor behind the left thyroid gland. Embolization of the left thyroid artery was performed. However, the next day, airway obstruction.was occurred and she was brought to our hospital. An emergency operation was performed to open the left neck swelling region. The operation findings and pathological examination showed that the bleeding was caused by a parathyroid cyst and airway obstruction had occurred because of retropharyngeal edema. In this case, the bleeding may have been caused by torsion of the neck when the patient exercised. The retropharyngeal edema probably resulted from the delay of delivery of the lymphatic and venous return and the arterial embolization. 1 year after the operation, the patient is very well and there has been no recurrence.
    No preview · Article · Sep 2014 · Nippon Jibiinkoka Gakkai Kaiho
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    ABSTRACT: To assess the clinical outcomes of single or oligo-fractionated stereotactic radiotherapy (SRT) using dynamic conformal arcs (DCA) for head and neck tumors (HNTs). Thirty-four consecutive patients with 35 lesions treated between 2005 and 2009 were retrospectively evaluated, of whom 85.7 % had recurrent or metastatic disease, and 45.7 and 34.3 % had previous radiotherapy and surgery, respectively. The median SRT dose was 22.3 Gy (11.2-32.8) in 2-4 fractions with a median interval of 7 days and 10.4 Gy (9.2-12.4) in one fraction. SRT was combined with upfront conventionally fractionated RT in 48.6 % of patients. The median follow-up periods were 18.4 months (2-84.1) for the entire cohort and 49.6 months for the survivors. The 1- and 2-year local control (LC) rates were 84.3 and 70.5 %, with the 1- and 2-year overall survival (OS) rates of 78.6 and 51.6 %. LC was significantly better for tumor volumes <25.6 cm(3) (p = 0.001). OS was significantly longer in patients without any disease outside the SRT site (p < 0.001), whereas LC after the SRT did not affect the OS. Late adverse events occurred in 9 patients, including cranial nerve (CN) injury (grade 3/4) in 2, brain radionecrosis in 5 (grade 1), and fatal bleeding in 2 patients harboring uncontrolled lesions abutting the carotid artery. DCA-based SRT can confer relatively long-term LC with acceptable toxicity in selected patients with HNTs. The patients with CN involvement or tumor volume ≥25.6 cm(3) were deemed unsuitable for this treatment regimen.
    Full-text · Article · Apr 2012 · Journal of Cancer Research and Clinical Oncology
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    ABSTRACT: We studied treatment satisfaction in 1,903 subjects with Japanese cedar pollinosis, seen in Gifu Prefecture institutions in 2009, a mass scattering year. Institution physicians determined the choice of therapeutic drugs. We evaluated subject satisfaction and symptoms by questionnaire using nasal and eye symptom scores evaluated by the visual analog scale (VAS) in the pretreatment stage, in the stage with the severest symptoms, and in the posttreatment stage. Antihistamines were most widely used, followed by topical nasal steroids, and leukotriene antagonists, in this order. More subjects were treated with 2 types of drug combined than with a single drug alone. Satisfaction (very good plus good) was found in 68.8% of 747 subjects. The most frequent cause of dissatisfaction was insufficient therapeutic effect. Higher nasal symptom VAS was significantly related to satisfaction.
    No preview · Article · Nov 2010
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    ABSTRACT: A 60-year-old man seen for a giant right cervical mass and hemiplegic gait disturbance was found in computed tomography (CT) and magnetic resonance imaging (MRI) to have a large cervical tumor pressing laterally on the carotid artery in the right parapharyngeal space and an intracranial tumor destroying the first cervical spine and cranial base. Cervical tumor biopsy identified schwannoma. Fluid volume from the cervical tumor discharged after biopsy and relieving left arm and leg weakness indicated that the cervical tumor, deriving from the sympathetic nerve, had adversely affected neurological signs via the intracranial mass derived from the cervical spinal radix. We removed the cervical tumor prior to the intracranial lesion, after which he could walk independently.
    No preview · Article · Jul 2010
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    ABSTRACT: Middle-ear carcinoma is very rare, and primary radical surgery followed by adjuvant radiotherapy is held to give better survival than radical radiotherapy alone. If resection produces no cure, chemoradiation may be attempted but curability using conventional external irradiation is low. A 56-year-old woman with unresectable advanced middle-ear carcinoma was found in computed tomography to have irregularly enhanced soft tissue filling the right external auditory canal, middle ear cavity, and mastoid, and diffusely destroyed temporal bone. The tumor had destroyed the carotid artery bone canal. Enhanced magnetic resonance imaging showed diffusely thickened posterior fossa dura mater. She was treated successfully with conventional external irradiation and subsequent stereotactic irradiation combined with chemotherapy. Stereotactic irradiation thus proved extremely effective against local residual and metastatic bone lesions.
    No preview · Article · Apr 2010
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    ABSTRACT: We report a 46-year-old man with bacterial meningitis and left cerebrospinal fluid (CSF) otorrhea associated with inner ear malformation (common cavity type). Left tympanotomy showed granulation over the stapes and water-like otorrhea, and the stapes was separated from the thickened incus long arm. A partial defect was present in the stapes foot plate, and removal of the stapes led to pronounced leakage of CSF. We therefore packed the vestibule with fascia and small pieces of auricular cartilage tightly and then positioned the cap of the vestibule with fascia and fibrin glue. He has remained well and free from meningitic symptoms for two years after the operation. Our case indicates that the occlusion of the vestibule with fascia and auricular cartilage should be considered even in cases without a history of meningitis.
    No preview · Article · Jan 2009

  • No preview · Article · Jan 2009 · Nihon Kikan Shokudoka Gakkai Kaiho
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    ABSTRACT: To investigate the relationship between white matter lesions identified on MRI and balance dysfunction in elderly persons, we evaluated findings on brain MRI and body sway examined with a stabilometer in persons (n=49) aged over 50 years old who were hospitalized for a thorough medical checkup. The total number and major axes of spots indicating deep white matter, hyperintense signals (DWMH) on MRI were measured. If the total number of spots exceeded 10 or the major axes exceeded 4 mm, white matter changes were judged to be severe. Sway of the body is center of gravity was recorded with eyes open and closed for 60 seconds using a stabilometer. The sway area and locus length, as well as left-right (X position) and forward-backward (Y position) deviation of the center of sway were measured. The measurements regarding these parameters were compared with standard values in healthy subjects. Persons with normal values in all 4 parameters (sway area and right-left deviation with eyes open and closed) were regarded as stable, and persons with values beyond the normal range were regarded as unstable. Elderly persons with severe white matter lesions on MRI identified on a thorough medical checkup were significantly unstable. We suggested that elderly persons with severe white matter lesions tended to exhibit postural abnormalities due to brain arteriolosclerosis. Tokita proposed the usefullness of stabilometry on health examination to check the health condition and detect any signs of Cerebrovascular disorders. We believe that our results also showed the utility of stabilometry in health examinations.
    No preview · Article · Jun 2007 · Equilibrium Research
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    ABSTRACT: White matter high intensity lesions on T2-weighted magnetic resonance imaging (MRI) are often detected in aged people. Arteriosclerosis appears to be the most important causative factor in the development of such high intensity signals, and the extent of white matter lesions is thought to reflect the extent of brain arteriosclerosis. We reported that elderly patients with dizziness, especially of central origin, showed significantly more severe white matter lesions. To investigate the relationship between these white matter lesions identified on magnetic resonance imaging and balance dysfunction in elderly patients, we evaluated findings on brain MRI and body sway examined by a stabilometer in patients with dizziness (n=79) aged over 60 years old. Deep white matter hyperintense signals (DWMH) and periventricular hyperintensity (PVH) on MRI was graded usig a qualitative rating scale (Fazekas et al.). Sway of the body's center of gravity was recorded with eyes open and closed for 60 seconds using a stabilometer. Sway area, locus length, and right-left (X position) and forward-backward (Y position) deviations of the center of sway were measured. The measurement values of these parameters were compared with standard values in healthy subjects. Patients with normal values in all 8 items were regarded as stable, and patients with values beyond the normal range were regarded as unstable. In patients with dizziness aged 60-79 years old, those with severe white matter lesions (grade 2-3) on MRI were signifi-cantly unstable. We suggested that elderly patients with severe white matter lesions tended to have postural abnormalities and show dysfunction of the central nervous system due to brain arteriolosclerosis.
    No preview · Article · Jun 2006 · Equilibrium Research
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    ABSTRACT: High intensity signals on T2-weighted magnetic resonance imaging (MRI) of cerebral white matter are common in aged people. A recent study suggests that these lesions increase with risk factors for stroke from arteriolosclerosis. Some investigators have identified a relationship between these white matter lesions and dementia or motor deficits. The clinical significance of these white matter lesions remains unclear. To investigate the relationship between these white matter lesions identified on magnetic resonance imaging and dizziness in elderly patients, we evaluated findings on brain MRI of patients with dizziness (n=108) and patients without dizziness (n=28) aged over 60 years old. Deep white matter hyperintense signals (DWMH) and periventricular hyperintensity (PVH) were graded using a qualitative rating scale (Fazekas et al.). Patients with dizziness, especially originating in the central nervous system, showed significantly more severe white matter lesions (grade 2-3). We suggest that older patients with severe white matter high intensity signals experience dizziness due to vascular insufficiency from arteriolosclerosis.
    No preview · Article · Jun 2006 · Equilibrium Research
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    ABSTRACT: Patients with Takayasu's arteritis (TA) rarely suffer sensorineural hearing loss (SNHL), which can be comparatively restored by corticosteroid therapy. We report a 65-year-old woman with aortitis with arch vessel involvement and bilateral severe SNHL. Although her profound deafness failed to improve with corticosteroids, cochlear implantation improved her hearing loss without postoperative problems. Her postoperative open-set syllable recognition without lip reading after cochlear implantation was 90%. When medical treatment fails to improve bilateral severe hearing loss without benefit from hearing aids in TA patients, cochlear implantation is indicated.
    No preview · Article · Jan 2006
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    ABSTRACT: In order to assess an association between orthostatic dysregulation (OD) and stress, we investigated the life-change-unite (LCU) score of dizzy patients with OD (n =258) and dizzy patients without OD (n=252) using the social readjustment rating scale (Holmes & Rahe, 1967), and also depression scores of the patients with a self-rated questionnaire for depression (SRQ-D). Nonparametric statistics used to analyze the data showed that at the .01 level of confidence, dizzy patients with OD had a significantly higher stress score than the dizzy patients without OD. Forty-eight percent of the patients with OD showed a significantly higher rate score on the SRQ-D, over 16 points, indicating that they were depressed, compared with that of the patients without OD. Particularly in the group of the dizzy male patients with OD between 40 and 64 years of age, rank order correlations between patients LCU total and depression scores proved significant by Kendall's. We suggest that stress may be related to dizziness with OD and that a psychological approach may be useful for treatment of dizziness with OD.
    No preview · Article · Aug 2004 · Equilibrium Research
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    ABSTRACT: Postural tachycardia syndrome (POTS) has recently been recognized as a syndrome in which patients have an increased heart rate without orthostatic hypotension. Patients with POTS may complain of presyncope, vertigo, dizziness, light-headedness, general fatigue or unsteadiness. However, the etiology of POTS is unclear. We report a typical case of POTS; a 24 year-old woman who had suffered from dizzy sensations during postural changes for six months. No abnormalities had been observed in ECG, echocardiography, clinical chemistry, blood test and brain MRI. On the first visit, no abnormal responses were noted on neuro-otological examinations or for the CMI and SRQ-D psychological questionnaires. However, the patient's heart rate increased by 34 beats/min from supine to standing position, and in addition, she complained of a headache and fatigue without hypotension during Schellong test. Power spectral analysis of RR interval variability during Schellong test revealed that the normalized powers of low frequency (LFnp) and ratio of LF and high frequency powers (LF/HF) increased when standing upright from supine position. We diagnosed her with POTS and administered atenolol (β1 blocker, 50 mg every morning) in formula, which markedly reduced her subjective symptoms.
    No preview · Article · Jan 2000 · Equilibrium Research
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    ABSTRACT: A 64-year-old woman was affected with sudden bilateral hearing loss. She initially visited us complaining of right-sided accordingly hearing loss, which was diagnosed as right sudden deafness, and treated. Thereafter she indicated that vertigo, with right tinnitus, had increased. She was subsequently diagnosed with Ménière's disease. Thereafter she visited us complaining of left-sided hearing loss. After numerous clinical visits and extensive examinations, including MRI, she was diagnosed as having a bilateral acoustic tumor, although she didn't have the cafe-au-lait spots, induration under the skin, or small nodules of the iris and juvenile cataractas that are characteristic of Recklinghausen's disease. As her symptoms were atypical and the course of her disease was unusual for patient affected with an acoustic tumor in consideration of her age, we didn't recommend surgery. Presently she uses a hearing aid in the left ear.
    No preview · Article · Jan 1996

Publication Stats

10 Citations
3.08 Total Impact Points

Institutions

  • 1996-2012
    • Gifu University
      • Department of Otolaryngology
      Gihu, Gifu, Japan