C.-C. Lai

Taipei Veterans General Hospital, Taipei, Taipei, Taiwan

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Publications (2)0 Total impact

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    R B Tang · T Chao · S J Chen · C C Lai
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    ABSTRACT: Obesity imposes additional stress to ventilation during exercise. The purpose of this study is to evaluate the pulmonary function changes with graded exercise and the habitual level of physical activity in obese children. This study recruited 42 obese and 10 normal students, aged 11, from Tamsui Elementary School. Measurements of cardiopulmonary fitness were recorded after a jump rope test. Height, weight and body mass indices were determined before testing. A significant correlation was found between triceps skin-fold thickness and the body mass index (BMI; r = 0.65, p < 0.05). Blood systolic pressure significantly increased in the obese subjects in their post-exercise test. There was no significant difference between the obese and the non-obese groups in any of the lung function test measurements. Forced expiratory volume in the first second (FEV1), peak expiratory flow rate (PEFR) and forced vital capacity (FVC) were similar in both groups. Physiologic responses are not sufficiently different from between the obese subjects and the non-obese children. We should pay more attention to fostering confidence in the obese child exercise.
    Preview · Article · Aug 2001 · Zhonghua yi xue za zhi = Chinese medical journal; Free China ed
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    ABSTRACT: Advances in neonatal intensive care have led to improved survival of very low birth weight infants (VLBW, birth body weight < 1,500 gm). However, these immature, immunocompromised infants have prolonged hospitalizations and are vulnerable to nosocomial infection. Sepsis remains one of the major causes of morbidity. The purpose of this study was to evaluate the incidence, risk factors, distribution of pathogens and correlation of mortality with sepsis in VLBW infants. All 612 infants in the study were admitted to 17 hospitals in Taiwan during 1996. Their mean gestational age was 28.9 +/- 3.0 weeks (21∼38 weeks), and mean birth body weight was 1,133 +/- 272 grams (368∼1,500 grams). There were 281 boys and 295 girls, with gender not specified by the registry in 36 cases. One hundred and fifty-two babies (24.8%) had sepsis. The infants who survived beyond 3 days had a higher incidence of sepsis than those who died during the first 3 days (27.8% vs 7.7%). Gestational age and ventilator use were significantly related to sepsis (p< 0.05), while gender and birth body weight were not. Also, sepsis was correlated with mortality in the group who survived beyond the age of 3 days. Forty-four percent of the microorganisms isolated from the blood culture were Gram positive cocci with Staphylococcus epidermidis as the leading microorganism (33%). Thirty-eight percent were Gram negative baccilli with Klebsiella and Enterobacter as the leading microorganisms (25%). Therefore, sepsis was a very serious problem for VLBW infants due to high morbidity and mortality. Successful strategies to decrease sepsis, including prolonging gestation should decrease the mortality rates and reduce the medical cost of VLBW infants.
    No preview · Article · Jun 2001 · Clinical Neonatology