Nurziana Ngah

International Islamic University Malaysia, Kuala Lumpor, Kuala Lumpur, Malaysia

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Publications (44)14.46 Total impact

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    ABSTRACT: In the title compound, C10H11FN3O3S, the 2-fluoro-benzoyl and proponic acid groups maintain a trans-cis conformation with respect to the thiono C=S bond across their C-N bonds. The propionic acid group adopts an anti conformation about the C-C bond, with an N-C-C-C torsion angle of 173.8 (2)°. The amino groups are involved in the formation of intra-molecular N-H⋯O and N-H⋯F hydrogen bonds. In the crystal, pairs of O-H⋯O hydrogen bonds link mol-ecules into inversion dimers.
    Full-text · Article · Jun 2014 · Acta Crystallographica Section E Structure Reports Online
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    Azizah Mahmood · Muhammad Nor Omar · Nurziana Ngah
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    ABSTRACT: To investigate the potential of Musa x paradisiaca (M. x paradisiaca) flower extracts in promoting milk production of lactating rats and its effects on growth of the suckling pups. Galactagogue activity was evaluated in terms of quantity of milk produced from the rats treated with petroleum ether, ethanol or water extracts of the flower. Lactating rats (n = 5) of Spraque Dawley with six pups each were administered with the extracts in the amount of 500 mg/kg body weight, while the control rats were given an equivalent amount of distilled water. The rats were daily administered via oral feeding starting from Day 5 until Day 14 and the performance of milk production was measured along the experimental period by weight-suckle-weight method. Results were statistically analyzed using SPSS by means of ANOVA at 0.05 and was expressed as their mean?standard deviation. The rates of pups' growth were measured as the weight gain along the experimental period. The rats treated with aqueous extract produced higher milk than control and ethanol groups. Aqueous extract was identified to increase milk production by 25%, while petroleum ether extract by 18%. The mean of yields produced by the rats during suckling period for aqueous, petroleum ether, ethanol and control were 4.62±2.45, 4.37±1.93, 3.65±1.89 and 3.69±1.79, respectively. Growth rates of pups for the rats treated with control, aqueous, ethanol extract and petroleum ether were (1.85±0.49), (1.78±0.56), (1.65±0.46) and (1.56±0.42) g/pup, respectively. The present study reveals the potential of M. x paradisiaca flower to enhance milk production of nursing mothers which could be exploited for commercialization of the isolated extract.
    Full-text · Article · Nov 2012 · Asian Pacific Journal of Tropical Medicine
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    ABSTRACT: In the title compound, C(14)H(18)N(2)O(3), the carb-oxy-lic group is tilted by 12.00 (4)° with respect to the mean plane throught the benzimidazole ring system. The alcohol and carboxyl hydroxy groups are involved in intermolecular O-H⋯O and O-H⋯N hydrogen bonds, forming a two-dimensional network extending parallel the ab plane. The network is further stabilized by weak C-H⋯O inter-actions. The sec-butyl group is disordered over two sets of sites with refined occupancies of 0.484 (4) and 0.516 (4).
    Full-text · Article · Jul 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: The asymmetric unit of the title compound, C(11)H(12)ClN(3)O(3)S, contains two independent mol-ecules with different conformations in which the benzene ring and the thio-urea fragment form dihedral angles of 87.28 (12) and 66.44 (10)°. The O atom of the thio-amide group is involved in bifurcated N-H⋯O intra- and inter-molecular hydrogen bonding; the latter inter-action links the independent mol-ecules into a dimer. In the crystal, N-H⋯S inter-actions link the mol-ecules into chains propagating along the c axis.
    Full-text · Article · Jun 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: The asymmetric unit of the title compound, C11H12ClN3O3S, contains two independent mol­ecules with different conformations in which the benzene ring and the thio­urea fragment form dihedral angles of 87.28 (12) and 66.44 (10)°. The O atom of the thio­amide group is involved in bifurcated N—H⋯O intra- and inter­molecular hydrogen bonding; the latter inter­action links the independent mol­ecules into a dimer. In the crystal, N—H⋯S inter­actions link the mol­ecules into chains propagating along the c axis.
    Full-text · Article · May 2012 · Acta Crystallographica Section E Structure Reports Online
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    M Sukeri M Yusof · Bohari M Yamin · Nurziana Ngah
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    ABSTRACT: The benzene rings of the biphenyl group in the title compound, C(20)H(14)ClN(3)O(3)S, are nearly coplanar [maximum deviation = 0.20 (3) Å]. The mean plane of the biphenyl group forms a dihedral angle of 5.24 (7)° with the aromatic ring of the nitro-chloro-benzene group. Intra-molecular N-H⋯Cl, N-H⋯O and C-H⋯S hydrogen bonds stabilize the cis-trans conformation of the mol-ecule. In the crystal, mol-ecules are linked by C-H⋯O and C-H⋯S hydrogen bonds into mutually inter-woven corrugated layers parallel to (10-2).
    Preview · Article · May 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: The asymmetric unit of the title compound, C(11)H(12)Cl(2)N(2)OS, contains two crystallographically independent mol-ecules with different conformations: the benzene ring and the thio-urea fragment form dihedral angles of 74.32 (11) and 89.39 (11)°. One amino group in each mol-ecule is involved in intra-molecular N-H⋯O and inter-molecular N-H⋯O hydrogen bonding: the latter links pairs of independent mol-ecules into dimers. In the crystal, weak N-H⋯S inter-actions link these dimers into chains propagating along the c axis.
    Full-text · Article · May 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: The asymmetric unit of the title compound, C11H12Cl2N2OS, contains two crystallographically independent mol­ecules with different conformations: the benzene ring and the thio­urea fragment form dihedral angles of 74.32 (11) and 89.39 (11)°. One amino group in each mol­ecule is involved in intra­molecular N—H⋯O and inter­molecular N—H⋯O hydrogen bonding: the latter links pairs of independent mol­ecules into dimers. In the crystal, weak N—H⋯S inter­actions link these dimers into chains propagating along the c axis.
    Full-text · Article · Apr 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the title mol-ecule, C(19)H(20)N(2)O(4)·H(2)O, the benzimidazole ring system is essentially planar [maximum deviation = 0.013 (11) Å] and is inclined to the 4-meth-oxy-phenyl ring by 30.98 (5)°. In the crystal, O-H⋯O and O-H⋯N hydrogen bonds involving the water mol-ecule link neighbouring mol-ecules, forming a two-dimensional network lying parallel to the bc plane. There are also C-H⋯π and π-π inter-actions present. The latter involve inversion-related benzimidazole rings with centroid-centroid distances of 3.5552 (8) and 3.7466 (8) Å.
    Full-text · Article · Feb 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the title compound, C18H20BrNO3, the oxazolidine ring adopts an envelope conformation with the N atom at the flap position. The mean plane of oxazolidine ring makes dihedral angles of 82.96 (13) and 70.97 (12)degrees, respectively, with the phenyl and benzene rings. In the crystal, adjacent molecules are connected via O-H center dot center dot center dot O and C-H center dot center dot center dot O hydrogen bonds and C-H center dot center dot center dot pi interactions into a zigzag chain along the b axis.
    Full-text · Article · Jan 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the crystal structure of the title compound, C(15)H(20)N(2)O(3)S, the hy-droxy group is involved in the formation of O-H⋯N hydrogen bonds, which link two mol-ecules into a centrosymmetric dimer. Weak C-H⋯O hydrogen bonds further link these dimers into chains propagating along the a axis. The crystal packing exhibits π-π inter-actions between the five- and six-membered rings of neighbouring mol-ecules [centroid-centroid distance = 3.819 (2) Å] and short inter-molecular S⋯S contacts of 3.495 (1) Å.
    Full-text · Article · Jan 2012 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the title compound, C(20)H(21)BrN(2)O(2), the bromo-phenyl ring is twisted by 40.13 (8)° from the benzimidazole mean plane and the Br atom deviates by 0.753 (1) Å from that plane. The sec-butyl group is disordered over two conformations in a 0.898 (5):0.102 (5) ratio. In the crystal, mol-ecules related by translation along [[Formula: see text]10] are linked into chains via weak C-H⋯Br hydrogen bonds.
    Preview · Article · Dec 2011 · Acta Crystallographica Section E Structure Reports Online
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    Azizah Mahmood · Nurziana Ngah · Muhammad Nor Omar
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    ABSTRACT: The objective of this study is to find out qualitatively and quantitatively phytochemical constituents and antioxidant activities in the flower of Musa x paradisiaca extracts. The extracts from various solvents; petroleum ether, chloroform, ethanol and water were investigated for the presence of alkaloid, saponin, glycoside, tannin, flavanoid, terpenoid and steroid. Particular reagents were used to screen phytochemicals in the samples and their presence was indicated by the changes of colour, precipitation or turbidity. Phytochemicals studies on banana flower extracts showed the presence of alkaloids, glycosides, steroids, saponins, tannins, flavanoids and terpenoids. Quantitative analysis by gravimetric method showed that the flower of M. x paradisiaca contains 1.56 ± 0.2 g/100g alkaloid and 1.43 ± 0.14 g/100g saponin. In spectrometric method, the flower also contains 5.83 ± 0.78 g/100g total phenolic, 88.31 ± 4.53 mg/100g tannin and 3.98 ± 0.01 mg/100g flavanoid. DPPH (1, 1-diphenyl-2-picrylhydrazyl) free radical scavenging assay of ethanol extract demonstrated stronger antioxidant activity than aqueous extract in which the IC 50 value were 1.01 ± 0.16 mg/ml and 1.52 ± 0.13 mg/ml, respectively.
    Full-text · Article · Dec 2011
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    ABSTRACT: In the title compound, C21H24N2O3, the mean planes of the benzene ring and the benzimidazole ring system form a dihedral angle of 69.94 (7)degrees. The ethyl group atoms of the ethanoate fragment are disordered over two sets of sites, with refined occupancies of 0.742 (6) and 0.258 (6). In the crystal, there are weak C-H center dot center dot center dot N hydrogen bonds which connect molecules into chains along the b axis. A weak intermolecular C-H center dot center dot center dot pi interaction is also observed.
    Full-text · Article · Dec 2011 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the title compound, C(20)H(21)FN(2)O(2), the benzene ring and the benzimidazole ring system are inclined at a dihedral angle of 44.40 (9)°. In the crystal, mol-ecules are linked by inter-molecular C-H⋯O hydrogen bonds, forming a zigzag chain along the b-axis direction. An intra-molecular C-H⋯π inter-action is also observed.
    Preview · Article · Nov 2011 · Acta Crystallographica Section E Structure Reports Online
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    ABSTRACT: In the title compound, C(15)H(20)N(2)O(3), the benzimidazole ring is essentially planar, with a maximum deviation from the mean plane of 0.012 (1) Å. The crystal structure is stabilized by inter-molecular O-H⋯N hydrogen bonds, forming centrosymmetric dimers, which are connected in the [100] direction through weak C-H⋯O contacts.
    Full-text · Article · Oct 2011 · Acta Crystallographica Section E Structure Reports Online
  • A Mahmood · M N Omar · N Ngah

    No preview · Article · Sep 2011 · International Journal of Evidence-Based Healthcare
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    ABSTRACT: In the title compound, C14H12N2O2S, the benzoyl and 3-hydroxyphenyl fragments adopt trans–cis positions with respect to the S atom across their C—N bonds. The dihedral angle between the 3-hydroxyphenyl and N2CS thiourea groups is 72.09 (8)°. The crystal structure is stabilized by O—H...S and N—H...S hydrogen bonds, forming a polymeric chain along the c axis.
    No preview · Article · May 2007 · Acta Crystallographica Section E Structure Reports Online

  • No preview · Article · Jan 2007
  • Nurziana Ngah · Mohammad B. Kassim · Bohari M. Yamin

    No preview · Article · Oct 2006 · Acta Crystallographica Section E Structure Reports Online

Publication Stats

50 Citations
14.46 Total Impact Points

Institutions

  • 2011-2014
    • International Islamic University Malaysia
      Kuala Lumpor, Kuala Lumpur, Malaysia
  • 2012
    • University of Science Malaysia
      • School of Pharmaceutical Sciences
      Nibong Tepal, Pulau Pinang, Malaysia
  • 2005-2007
    • National University of Malaysia
      • School of Chemical Sciences and Food Technology
      Putrajaya, Putrajaya, Malaysia
    • International Union of Toxicology
      Reston, Virginia, United States
  • 2006
    • University of Malaya
      • Department of Chemistry
      Kuala Lumpor, Kuala Lumpur, Malaysia