Nina Schädle

University of Wuerzburg, Würzburg, Bavaria, Germany

Are you Nina Schädle?

Claim your profile

Publications (3)3.05 Total impact

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: We performed a comparative study using Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) to measure intraocular pressure (IOP) in eyes with keratoconus. IOP was measured in 114 eyes of 75 patients with keratoconus (51 men and 24 women; mean age, 36.1 ± 11.2 years) using GAT and DCT in randomized order. Central corneal thickness (CCT), minimal corneal thickness (MCT), and corneal topography were recorded using the Pentacam. Four groups according to Amsler's keratoconus classification were composed and analyzed for significant differences of CCT, MCT, GAT, and DCT results. Mean CCT in the 114 keratoconus eyes was 481.1 ± 46.2 μm (range, 334-601 μm). Mean MCT was 453.3 ± 56.3 μm (range, 239-573 μm). Mean IOP measured using GAT was 13.1 ± 2.9 mm Hg, whereas mean IOP measured using DCT was 14.8 ± 2.6 mm Hg. Neither the results for GAT nor those for DCT showed a significant correlation with CCT (Pearson correlation: P < 0.05). Multifactorial analysis revealed that CCT and MCT, but not GAT and DCT, results were significantly different in corneas of varying curvatures. This study shows that DCT measures IOP higher than GAT in eyes with keratoconus. In keratoconus, both methods seem to be independent of CCT and therefore are equally, but not interchangeably, applicable when monitoring IOP. Further analysis revealed that CCT and MCT are significantly different in corneas of varying Amsler grade.
    Full-text · Article · Jun 2011 · Cornea
  • N. Schädle · J.D. Unterlauft · T. Klink · G. Geerling
    [Show abstract] [Hide abstract]
    ABSTRACT: Purpose The gold standard for measuring intraocular pressure (IOP) until now has been Goldmann applanation tonometry (GAT), which depends on the central corneal thickness (CCT) and curvature. In patients with keratoconus who have an abnormal corneal geometry and thickness, measurement of pressure with GAT is often difficult and not very reproducible. We compared the impact of the central corneal thickness (CCT) on the IOP measured with dynamic contour tonometry (DCT), a digital method which is adapted to the corneal geometry, and GAT in patients with keratoconus. Methods IOP was measured in 54 patients (38 men and 16 women, mean age of 36±9.9 years) with GAT and DCT in randomized order. All patients had a keratoconus which was assured by topography. In addition central corneal thickness (CCT) was measured with the Pentacam. For statistical analysis the Pearson correlation was calculated and a Bland-Altman diagram plotted. Results Mean corneal thickness was 486.2±45.5 μm. DCT measured the IOP at a mean value of 14.9±2.6 mmHg and GAT at 13.3±2.9 mmHg. With a mean difference of 1.6±2.4 mmHg DCT measured significantly higher than GAT (p≤0.05) Neither IOP measurements with GAT (r=−0.03; p>0.05) nor those with DCT (r=0.08; p>0.05) showed a significant correlation to central corneal thickness. Conclusion The example of keratoconus confirms that IOP measured by GAT is lower than if measured by DCT. Because both methods are independent of the CCT they are equally acceptable for IOP follow-up in eyes with keratoconus, which may result in progressive corneal thinning in the long term.
    No preview · Article · Jun 2009 · Der Ophthalmologe
  • N Schädle · J D Unterlauft · T Klink · G Geerling
    [Show abstract] [Hide abstract]
    ABSTRACT: The gold standard for measuring intraocular pressure (IOP) until now has been Goldmann applanation tonometry (GAT), which depends on the central corneal thickness (CCT) and curvature. In patients with keratoconus who have an abnormal corneal geometry and thickness, measurement of pressure with GAT is often difficult and not very reproducible. We compared the impact of the central corneal thickness (CCT) on the IOP measured with dynamic contour tonometry (DCT), a digital method which is adapted to the corneal geometry, and GAT in patients with keratoconus. IOP was measured in 54 patients (38 men and 16 women, mean age of 36+/-9.9 years) with GAT and DCT in randomized order. All patients had a keratoconus which was assured by topography. In addition central corneal thickness (CCT) was measured with the Pentacam. For statistical analysis the Pearson correlation was calculated and a Bland-Altman diagram plotted. Mean corneal thickness was 486.2+/-45.5 microm. DCT measured the IOP at a mean value of 14.9+/-2.6 mmHg and GAT at 13.3+/-2.9 mmHg. With a mean difference of 1.6+/-2.4 mmHg DCT measured significantly higher than GAT (p<or=0.05) Neither IOP measurements with GAT (r=-0.03; p>0.05) nor those with DCT (r=0.08; p>0.05) showed a significant correlation to central corneal thickness. The example of keratoconus confirms that IOP measured by GAT is lower than if measured by DCT. Because both methods are independent of the CCT they are equally acceptable for IOP follow-up in eyes with keratoconus, which may result in progressive corneal thinning in the long term.
    No preview · Article · Aug 2008 · Der Ophthalmologe

Publication Stats

9 Citations
3.05 Total Impact Points

Top Journals

Institutions

  • 2011
    • University of Wuerzburg
      Würzburg, Bavaria, Germany