Chen-Lu Yang

Sichuan University, Hua-yang, Sichuan, China

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Publications (2)1.81 Total impact

  • Chen-lu Yang · Jin Wen · You-ping Li · Ying-kang Shi
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    ABSTRACT: The objective of this study is to evaluate the efficacy of cardiocerebral resuscitation (CCR) vs cardiopulmonary resuscitation (CPR) for patients with out-of-hospital cardiac arrest (OHCA). We conducted a systematic review of controlled trials and observational studies. We searched Cochrane Central Register of Controlled Trials; MEDLINE; Embase; and Chinese databases such as VIP, CNKI, WANFANG, and CBM from their inception to September 2010. Data from original studies were extracted and assessed with predefined criteria. Thirteen studies comprising 3 randomized controlled trials and 10 observational studies were included. Pooled analysis of 4 observational studies suggested that neurologically intact survival of patients with OHCA was improved in CCR group (odds ratio [OR], 1.45; 95% confidence interval [CI], 1.07-1.97). Survival to hospital discharge in the CCR group was superior or at least equal to that in CPR group (randomized controlled trial OR, 1.25; 95% CI, 1.01-1.55; cohort studies OR, 1.15; 95% CI, 0.72-1.82; case-control studies OR 0.85; 95% CI, 0.65-1.12). In the subgroup analysis of patients with a shockable rhythm as an initial rhythm, survival to hospital discharge was significantly improved in the CCR group (cohort studies OR, 2.03; 95% CI, 1.44-2.86). However, when only noncardiac origin cardiac arrest was taken into consideration, survival rate was better in the CPR group (cohort studies OR, 0.87; 95% CI, 0.77-0.98). Cardiocerebral resuscitation might be equivalent or superior to CPR in patients with OHCA in both survival rate and neurologic benefits. Further work is needed to assess the efficacy of CCR for victims who had OHCA of noncardiac causes.
    No preview · Article · Apr 2011 · The American journal of emergency medicine
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    Jin Wen · Chen-Lu Yang · Ying-Kang Shi · You-Ping Li · Yu-Lin Ji · Jin Liu
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    ABSTRACT: Background On May 12, 2008, a large earthquake measuring 8.0 on the Richter scale struck Wenchuan County, Sichuan Province, China. To date, there has been no report specifically addressing the clinical features of traumatized geriatric patients in the earthquake. The objective of this study was to review the characteristics of injuries among aged inpatients and provide some experiences of emergency management for traumatized geriatric patients. Methods Medical records of earthquake-related geriatric inpatients in West China Hospital were reviewed retrospectively. Results Of the 1,856 inpatients, 400 (21.6) were ≥ 65 years old. Extremity, trunk and head injuries were present in 240 (60.0), 102 (25.5), and 37 (9.2) patients, respectively. Fracture (68.5, n = 274) was the most common type of injury. The mortality of earthquake-related geriatric patients was 4.8, which was higher than that of all earthquake-related patients. Conclusion Fracture was the most common type of trauma and the extremities were the predominant sites among geriatrics after the Wenchuan earthquake. The mortality of elderly inpatients was higher than that of other age groups. Considering the difficulty and complexity of managing patients with earthquake-related injuries, a multidisciplinary team of physicians should be organized as soon as possible after an earthquake. © 2010 Taiwan Society of Geriatric Emergency & Critical Care Medicine.
    Preview · Article · Sep 2010 · International Journal of Gerontology