Wei Xiao

East China University of Science and Technology, Shanghai, Shanghai Shi, China

Are you Wei Xiao?

Claim your profile

Publications (1)2.02 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Cell-penetrating peptides can carry a variety of biologically active molecules into cells. Here we have identified a novel CPP derived from the C-terminus of human extracellular superoxide dismutase (hC-SOD3) which was shown to be located throughout in the cytoplasm and nucleus by fluorescence microscopy investigation. Furthermore, when apoptin fused to hC-SOD3, it was translocated efficiently into HeLa cells resulting in antitumor activities. This study shows that hC-SOD3 has the potential to penetrate and translocate cargo molecules into cells and has no cytotoxicity at effective concentration.
    No preview · Article · Nov 2010 · Molecular Biology Reports

Publication Stats

10 Citations
2.02 Total Impact Points

Top Journals


  • 2010
    • East China University of Science and Technology
      • School of Pharmacy
      Shanghai, Shanghai Shi, China