Mostafa Z Ali

Cairo University, Al Qāhirah, Muḩāfaz̧at al Qāhirah, Egypt

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Publications (3)1.74 Total impact

  • Mostafa Z Ali
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    ABSTRACT: Cervical meningoceles are rare. Clinical, radiological and surgical data of 8 cases were presented, including a unique case of double cervical and lumbosacral meningoceles. This retrospective study included all children operated on for cervical meningocele from January 2004 to June 2009 at the Aburish Pediatric Hospital, Cairo University. Eight children (6 boys and 2 girls) were operated on. Their ages ranged between 2 months and 8 years. The clinical picture--apart form posterior cervical swelling--was almost normal. One case had paraplegia due to associated lumbosacral myelomeningocele (double meningocele). Four patients had associated hydrocephalus; 2 had Chiari malformation and 2 hydromyelia. The outcome after surgery for these lesions is excellent as the majority of the children have no or minimal neurological deficit and surgery does help in improving cosmesis and preventing the development of neurological deterioration.
    No preview · Article · Jun 2010 · Pediatric Neurosurgery
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    Mostafa Z Ali · Nasser A Fadel · Hesham A Abouldahab
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    ABSTRACT: To compare awake craniotomy using conscious sedation technique versus conventional general anesthesia (GA) for excision of low-grade glioma encroaching on eloquent brain. This prospective study included 40 patients ASA classification 1 and 2, aged 23-55 years, harboring low-grade glioma encroaching on eloquent brain. The study was carried out in the Neurosurgical Theatre in Kasr El-Aini Hospital, Cairo, Egypt, from January 2007 to November 2008. Twenty patients (group 1) received GA with endotracheal intubation and controlled ventilation. In group 2, awake craniotomy was carried out using local anesthetic infiltration, and intravenous injection of propofol and fentanyl. Forty patients completed the study. In the awake group, none of the patients received GA, 2 patients developed intraoperative agitation, 5 patients were over-sedated, and none of the awake patients developed intraoperative nausea or vomiting. Four patients in the GA group developed post-operative nausea and vomiting compared to one patient in the awake group, and this difference was statistically significant (p=0.039). The neurological outcome regarding motor power and/or speech was found better or with no fresh deficits, immediately postoperative in 90% of the awake group patients. This is compared to 40% in the GA group. The difference was statistically significant. At 6 months follow up, the results were 90% and 60%, but the difference was not statistically significant. Gross total tumor resection was achieved in 10 cases of the GA group versus 8 in the awake group; however, the difference was not statistically significant. Compared to GA, awake craniotomy is a relatively simple non-expensive procedure that allows tumor removal guided by physiology rather than anatomy.
    Preview · Article · Jul 2009 · Neurosciences
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    Hala M Goma · Mostafa Z Ali
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    ABSTRACT: To compare the anti-hypertensive effects of both remifentanil and esmolol infusion. This prospective comparative study was conducted on 20 patients (10 patients in each group), in the Neurosurgical Theater of Kasr Elaini Hospital, Cairo, Egypt from 2006 to 2008. The patients were divided into 2 equal groups. In group one, remifentanil was used as a bolus of one ug/kg intravenous (iv) in 30-60 seconds, followed by infusion at a rate of 0.25-0.5 ug/kg/min until the systolic blood pressure was <140 mm Hg. In group 2, esmolol was given as a 500 ug/kg iv bolus in 30 seconds followed by continued infusion of 100-300 ug/kg/min until systolic blood pressure was <140 mm Hg. Infusion was continued until the patients left the post anesthesia care unit (PACU). The onset time of decreasing blood pressure was shorter in group 2 (40+/-0.01 seconds) than group one (52.5+/-4.47 seconds). The PACU and hospital stay were comparable between both groups. Remifentanil can be used to control blood pressure during emergence of anesthesia after craniotomy for brain tumors. It has higher rapid recovery score than esmolol and other narcotics. In addition, it can be used when esmolol is contraindicated such as in cardiac patients, asthmatics, chronic obstructive pulmonary disease, or during pregnancy. Also, it decreases the need for postoperative analgesia and allows sedation if the infusion is continued as surgical patients are admitted to the ICU.
    Preview · Article · Apr 2009 · Neurosciences

Publication Stats

11 Citations
1.74 Total Impact Points

Top Journals


  • 2009-2010
    • Cairo University
      • Department of Neurosurgery
      Al Qāhirah, Muḩāfaz̧at al Qāhirah, Egypt