Jung Soo Kim

Kyungpook National University Hospital, Sŏul, Seoul, South Korea

Are you Jung Soo Kim?

Claim your profile

Publications (146)176.14 Total impact

  • Sung Jae Heo · Jung Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: Objective: In previous experiments, the crosshatching incision has been shown to be an effective method for the correction of cartilaginous deviations. Although the settings of the experiments were different from that of septoplasty, the crosshatching incision has been considered a useful method for septoplasty. Therefore, we attempted to determine the efficacy of the crosshatching incision technique under actual septoplasty surgical settings. Methods: Commercial pig ear cartilages were used for the following experiments: firstly, the crosshatching incision was performed with the cartilage in a partially fixed state (in order to approximate caudal and dorsal fixation of septal cartilage); secondly, for the purpose of approximating L-strut preservation in septoplasty, the crosshatching incision was performed while excluding a marginal area of 1cm on any two contiguous borders. After the experiments, the change of curvature was assessed. Results: Under fixation of two contiguous borders, the curvature of the cartilage did not straighten after using the crosshatching incision. Incisions preserving the L-strut were not effective either. Furthermore, unpredicted deviation and splitting of the cartilage developed after the crosshatching incision. Conclusions: Under actual surgical settings, the crosshatching incision was ineffective for the correction of septal deviation. Therefore, usefulness of the crosshatching incision needs to be re-evaluated.
    No preview · Article · Jan 2016 · Auris, nasus, larynx

  • No preview · Article · Sep 2015
  • [Show abstract] [Hide abstract]
    ABSTRACT: To obtain high-performance recyclable ethylene propylene diene rubber (EPDM), EPDM was chemically functionalized as follows: EPDM was grafted with citraconic acid (CCA) by radical melt polymerization to produce a grafted EPDM (EPDM-g-CCA), and EPDM-g-CCA was reacted with various amino acids by melt condensation reaction to give amidated copolymers (EPDM-g-CCA-2-Am, EPDM-g-CCA-7-Am, and EPDM-g-CCA-12-Am, where the n indicates the carbon number of amino acid), and then ionomers (EPDM-g-CCA/n-Am/Io) were prepared by melt reaction of EPDM-g-CCA/n-Ams with Zinc oxide (ZnO)/zinc stearate (ZnSt). The mechanical properties/compression set (CS) resistance (elasticity)/recyclability of pristine EPDM, EPDM-g-CCA, EPDM-g-CCA/n-Am, and ionomers sheet samples were compared. The tensile strength/modulus, tear strength, and elasticity of samples were mostly increased in the order of ionomers>EPDM-g-CCA/n-Ams>EPDM-g-CCA>pristine EPDM. The properties of ionomers increased significantly with increasing the carbon number in amino acid up to seven, and then levelled off or decreased a little. The tensile strength/elasticity (compression set resistance) of recyclable ionomer (EPDM-g-CCA/7-Am/Io) was found to be ∼9.42/∼2.31 times of pristine EPDM, respectively. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42718.
    No preview · Article · Aug 2015 · Journal of Applied Polymer Science
  • [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this work was to evaluate factors that influence local recurrence and survival after surgical resection of sinonasal malignant melanoma, using a large population-based multicenter study in Korea. Retrospective analysis was performed for 155 newly diagnosed sinonasal malignant melanoma patients gathered from 15 university hospitals throughout Korea. Demographic data, tumor characteristics, surgical approach, adjuvant treatment, recurrence, and outcomes were analyzed. Three-year and 5-year overall survival rates were 48.8% and 40.1%, respectively. Local recurrence rate was 46.6%, with a mean recurrence time of 15.5 months. On multivariate analysis, patients who underwent surgery that included an endoscopic approach showed decreased local recurrence rate (p = 0.042) and increased survival rate (hazard ratio [HR], 1.702; 95% confidence interval [CI], 1.007 to 2.875; p = 0.047) compared to those who underwent an external approach. Patients with postoperative radiotherapy showed a decreased local recurrence rate (p = 0.001), but without impact on survival rate. Male gender, tumor beyond the nasal cavity, and presence of distant metastasis were associated with poor survival. An endoscopic-including surgical approach was associated with improved local control and survival in sinonasal malignant melanoma patients. Postoperative radiotherapy helped increase the local control rate. © 2015 ARS-AAOA, LLC.
    No preview · Article · Jun 2015 · International Forum of Allergy and Rhinology
  • Source
    Seung Hwan Kim · Jung Soo Kim · Hae Yu Kim · Sun-Il Lee
    [Show abstract] [Hide abstract]
    ABSTRACT: Treatment of spontaneous intracerebral hemorrhage (ICH) remains controversial. However, an extensive hemorrhage with a poor mental status is suitable for surgical evacuation. Our experience with the transsylvian-transinsular (TS-TI) microsurgical approach for deep-seated basal ganglia (BG) ICH was investigated. A retrospective review was conducted on 86 patients with BG ICH who underwent an operation at the Department of Neurosurgery of our Hospital from September 2011 to October 2014. Thirteen patients underwent craniotomy and the TS-TI microsurgical approach for hematoma evacuation. Twenty-seven patients underwent conventional craniotomy with the trans-cortical transtemporal (TC-TT) approach, and 46 patients underwent a burrhole operation and hematoma drainage using a frameless stereotaxic device (ST). The average age distribution was similar. The preoperative Glasgow coma scale (GCS) was similar for the TC-TT and TS-TI groups. The pre-operative hematoma levels were higher in the TC-TT (109.4 ± 48.6 mL) and TS-TI (96.0 ± 39.0 mL) groups than in the ST group (46.5 ± 23.5 mL). The hematoma removal rate was 77% in the TC-TT group, 88% in the TS-TI group, and 34% in the ST group. The mean maintenance period of a hematoma catheter was 3.6 days in the ST group. The clinical outcome showed correlation with the preoperative neurological symptoms. The TS-TI group was superior to the TC-TT group for evacuation of an intracerebral hematoma.
    Preview · Article · Jun 2015
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Hyperbranched poly(amidoamine) conjugated silica (HBPcS) particles were synthesized by grafting poly(amidoamine) dendrimers on multiple-functional hybrid silica (MHS) particles containing three different organosilane functional groups. Due to advantageous combination of dendrimers, with ample and controlled amount of amine groups, and monodisperse and stable MHS particles from simple one-pot synthesis, the HBPcS particles can serve as multifunctional platforms for various applications. The growth of the amine functional groups of the HBPcS particles with the generation number was confirmed by monitoring the amide peaks in IR spectra as well as indirectly by monitoring the amount of the molecules that are bound to the functional groups. As a proof of principle, colorimetric sensors for Cd ions were prepared by employing the HBPcS particles and organic Cd ion sensing molecules. Notably, the sensor particles from HBPcS particles of different generations showed different detection ranges due to the increase in the amount of amine functionalities by grafting processes.
    Full-text · Article · May 2015 · Colloid and Polymer Science
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: BACKGROUND: Neisseria meningitidis (Nm) is a leading causative agent of bacterial meningitis in humans. Traditionally, meningococcal meningitis has been diagnosed by bacterial culture. However, isolation of bacteria from patients' cerebrospinal fluid (CSF) is time consuming and sometimes yields negative results. Recently, polymerase chain reaction (PCR)-based diagnostic methods of detecting Nm have been considered the gold standard because of their superior sensitivity and specificity compared with culture. In this study, we developed a loop-mediated isothermal amplification (LAMP) method and evaluated its ability to detect Nm in cerebrospinal fluid (CSF). METHODOLOGY/PRINCIPAL FINDINGS: We developed a meningococcal LAMP assay (Nm LAMP) that targets the ctrA gene. The primer specificity was validated using 16 strains of N. meningitidis (serogroup A, B, C, D, 29-E, W-135, X, Y, and Z) and 19 non-N. meningitidis species. Within 60 min, the Nm LAMP detected down to ten copies per reaction with sensitivity 1000-fold more than that of conventional PCR. The LAMP assays were evaluated using a set of 1574 randomly selected CSF specimens from children with suspected meningitis collected between 1998 and 2002 in Vietnam, China, and Korea. The LAMP method was shown to be more sensitive than PCR methods for CSF samples (31 CSF samples were positive by LAMP vs. 25 by PCR). The detection rate of the LAMP method was substantially higher than that of the PCR method. In a comparative analysis of the PCR and LAMP assays, the clinical sensitivity, specificity, positive predictive value, and negative predictive value of the LAMP assay were 100%, 99.6%, 80.6%, and 100%, respectively. CONCLUSIONS/SIGNIFICANCE: Compared to PCR, LAMP detected Nm with higher analytical and clinical sensitivity. This sensitive and specific LAMP method offers significant advantages for screening patients on a population basis and for diagnosis in clinical settings.
    Full-text · Article · Apr 2015 · PLoS ONE
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Neisseria meningitidis (Nm) is a leading causative agent of bacterial meningitis in humans. Traditionally, meningococcal meningitis has been diagnosed by bacterial culture. However, isolation of bacteria from patients' cerebrospinal fluid (CSF) is time consuming and sometimes yields negative results. Recently, polymerase chain reaction (PCR)-based diagnostic methods of detecting Nm have been considered the gold standard because of their superior sensitivity and specificity compared with culture. In this study, we developed a loop-mediated isothermal amplification (LAMP) method and evaluated its ability to detect Nm in cerebrospinal fluid (CSF). We developed a meningococcal LAMP assay (Nm LAMP) that targets the ctrA gene. The primer specificity was validated using 16 strains of N. meningitidis (serogroup A, B, C, D, 29-E, W-135, X, Y, and Z) and 19 non-N. meningitidis species. Within 60 min, the Nm LAMP detected down to ten copies per reaction with sensitivity 1000-fold more than that of conventional PCR. The LAMP assays were evaluated using a set of 1574 randomly selected CSF specimens from children with suspected meningitis collected between 1998 and 2002 in Vietnam, China, and Korea. The LAMP method was shown to be more sensitive than PCR methods for CSF samples (31 CSF samples were positive by LAMP vs. 25 by PCR). The detection rate of the LAMP method was substantially higher than that of the PCR method. In a comparative analysis of the PCR and LAMP assays, the clinical sensitivity, specificity, positive predictive value, and negative predictive value of the LAMP assay were 100%, 99.6%, 80.6%, and 100%, respectively. Compared to PCR, LAMP detected Nm with higher analytical and clinical sensitivity. This sensitive and specific LAMP method offers significant advantages for screening patients on a population basis and for diagnosis in clinical settings.
    Full-text · Article · Apr 2015 · PLoS ONE
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Two once-daily inhaled bronchodilators, indacaterol and tiotropium, are widely used as firstline therapy in stable COPD patients. This study was performed to compare the clinical efficacy and safety between indacaterol and tiotropium in patients with moderate-to-severe COPD. MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials were searched to identify all published randomized controlled trials (RCTs). The primary outcome was trough forced expiratory volume in 1 second (FEV 1) at week 12. Four RCTs were eligible for inclusion (three RCTs with moderate-to-severe COPD patients and one RCT with only severe COPD patients). Trough FEV1 at weeks 12 and 26 were not significantly different between indacaterol and tiotropium by the standardized mean difference with 0.014 (95% CI, -0.036, 0.063, I2= 23.5%) and with 0.037 (95% CI, -0.059 to 0.133, I2= 0%) along with differences in means of 0.003L and 0.014L, respectively. Indacaterol and tiotropium also showed similar St. George's Respiratory Questionnaire (SGRQ) total scores and percentages of patients with SGRQ improvement (-≥ 4 units) at week 26. The incidences of nasopharyngitis, serious cardiovascular events, and serious adverse events were not different between indacaterol and tiotropium, while those of cough (OR = 1.68, P < 0.001, and RR = 1.63) and COPD worsening (OR = 1.18, P = 0.003, and RR = 1.12) were higher for indacaterol than tiotropium. However, when one study with only severe COPD patients was removed from the meta-analysis, the difference in the incidence of COPD worsening between indacaterol and tiotropium became non-significant (OR = 1.13, P = 0.204, and RR = 1.09). The clinical efficacy and serious adverse events between indacaterol and tiotropium were equivocal in patients with moderate-to-severe COPD. Cough is a common complaint associated with indacaterol, and COPD worsening needs to be carefully monitored in severe COPD patients when treated with indacaterol.
    Full-text · Article · Mar 2015 · PLoS ONE
  • [Show abstract] [Hide abstract]
    ABSTRACT: Core–shell-type TiO2@mercaptopropyl-functionalized silica (MPS) particles were prepared for enhanced photocatalytic performance of TiO2. The MPS particles were adopted in the composite-type photocatalyst design so as to enhance the photo-catalytic activity through the chemical interaction between chemically modified substrate particles and organic dye molecules, although they do not have photocatalytic activity. Three organic dyes, rhodamine B, rhodamine 6G, and methyl orange, were selected for testing dye adsorption characteristics and photocatalytic activities of the TiO2@MPS particles, commercial P25, and unsupported TiO2 nanosols. Rhodamine B and rhodamine 6G dyes were adsorbed much more on the TiO2@MPS particles than P25, by factors of 6 and 43, respectively, while methyl orange molecules were adsorbed more readily on P25. Such difference in the dye adsorption characteristics of the two photocatalysts may be related with available functional groups and the dyes. This would lead to enhanced photocatalytic degradation of the dyes because of combined chemical and physical adsorption mechanisms. Toward the two rhodamine dyes, the TiO2@MPS particles show significantly enhanced photocatalytic activity per TiO2 than P25 under both UV and visible light irradiation. Especially under visible irradiation, the degradation rate constants of rhodamine B and rhodamine 6G molecules per TiO2 were higher, 18 and 45 times, respectively, for the TiO2@MPS particles than for P25. Toward methyl orange dye, the degradation rate constant per TiO2 was lower for the TiO2@MPS particles than for P25 under UV irradiation but it was eight times higher under visible irradiation. The TiO2@MPS particles were recyclable and their photocatalytic activity did not change at all at least for three repeated photo-degradation tests.
    No preview · Article · Mar 2015 · Journal of Materials Science
  • Yoon-Sung Lee · Won-Kyung Shin · Jung Soo Kim · Dong-Won Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: Core–shell structured SiO2 particles with different core diameters were synthesized by radical polymerization of 4-styrenesulfonic acid sodium salt with vinyl-functionalized SiO2 core particles and were used as Li+ ion-conducting fillers in composite polymer electrolytes. Composite polymer electrolytes prepared with core–shell SiO2 particles exhibited high ionic conductivity exceeding 10−3 S cm−1 at room temperature and good mechanical properties, allowing the preparation of a free-standing film with a thickness of 30 μm. Lithium-ion polymer cells composed of graphite negative electrode, composite polymer electrolyte and LiFePO4 positive electrode were assembled, and their cycling performance was evaluated. Cells assembled with a composite polymer electrolyte containing core–shell SiO2 particles with a core diameter of 250 nm exhibited good cycling performance in terms of discharge capacity, capacity retention and rate capability.
    No preview · Article · Feb 2015 · RSC Advances
  • [Show abstract] [Hide abstract]
    ABSTRACT: Silver nanowires with various aspect ratios were successfully synthesized using a polyol method. The diameter and length of the silver nanowires were controlled by changing the reaction variables of initial reaction temperature, injection rate, and molecular weight of poly(vinyl) pyrrolidone (PVP). Silver nanowires with small diameters were synthesized by lowering the initial reaction temperature, while those with longer length were obtained when PVP with a large molecular weight was used. In addition, silver nanowires with a high aspect ratio greater than 3000 were produced by controlling the injection rate of the silver source. For transparent conductive films, silver nanowire ink with a resistance of 10 Ω/square and a transmittance of 80% were produced using a mixture of silver nanowires with high and low aspect ratios.
    No preview · Article · Feb 2015 · Journal of Ceramic Processing Research
  • [Show abstract] [Hide abstract]
    ABSTRACT: Tailored nanostructured ORMOSIL particles, of raspberry shaped, hollow, and rattle type structures, were prepared by a selective dissolution of siloxane networks in composite ORMOSIL particles with a multilayered structure. The synthesis of monodisperse ORMOSIL particles involved a one-pot process in an aqueous solution using a binary or ternary mixture from three organosilanes, (3-aminopropyl)trimethoxysilane (APTMS), vinyltrimethoxysilane (VTMS), and/or phenyltrimethoxysilane (PTMS). In the following step, ORMOSIL particles were treated with a mixture of water and alcohol with mild heating. This mild etching process was efficient to selectively dissolve some of organosilane functional groups within the ORMOSIL particles but not their main silica frameworks, leading to formation of mesoporous particles. The strategy developed in this study is not only very facile, economical, and less time-consuming, but also more environmentally friendly by avoiding the use of corrosive etching chemicals and harsh reaction conditions. Surface roughness, core diameter, and shell thickness of the resultant mesoporous ORMOSIL particles were controlled by manipulating synthetic parameters such as the relative ratios of the silane monomers as well as the dissolution parameters such as temperature and type of solvent.
    No preview · Article · Jan 2015 · Journal of Colloid and Interface Science
  • Seung Hwan Kim · Jung Soo Kim · Kyung Han Nam

    No preview · Article · Jan 2015
  • Source
    Ji Hwan Jang · Jung Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: Due to improvements in emergency resuscitation provided by rescue teams, more trauma victims who could have died due to sudden heart failure at the scene are brought to the hospital following resuscitation. Most of these patients present with major organ injuries and hypovolemic shock at the time of trauma. However, head trauma associated with sudden heart arrest is rare. Here, we report a case of ring fracture with pontomedullary laceration that led to sudden heart arrest.
    Preview · Article · Dec 2014 · Journal of Korean Neurosurgical Society
  • [Show abstract] [Hide abstract]
    ABSTRACT: Long carbon fiber reinforced polypropylene (LCFP) composites were prepared at different fiber/resin input ratios and fiber lengths by extrusion and compression molding techniques. Fiber contents and fiber lengths were controlled by the carbon fiber/resin input ratio and screw extruder speed, respectively. The effects of the fiber content and fiber length on the mechanical properties of LCFP were investigated. The fiber length of the composites with the same fiber content decreased with an increase in screw speed. Further, the mechanical properties of the composites improved with an increase in the fiber content and mean fiber length. The fracture surfaces of the composites were investigated by scanning electron microscopy (SEM).
    No preview · Article · Dec 2014 · Fibers and Polymers
  • Hyo Jin An · Jung Soo Kim · K.-Y. Kim · Dae Young Lim · Dong Hyun Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: The purpose of this study is to elucidate the influence of carbon fiber (CF) content on the mechanical and thermal properties of long carbon fiber (LCF)-reinforced polyamide 6 (PA6) thermoplastic composites. PA6/LCF composites were manufactured by a twin-screw extruder. The average length of the carbon fibers in the composites was approximately 13–15 mm. We found that the interfacial adhesion between the PA6 matrix and the carbon fibers was very good. The mechanical properties, such as the tensile strength, the tensile modulus, and the flexural strength of the PA6/LCF composites, increased as the CF content increased and were higher than those of short carbon fiber reinforced PA6 composites. The melting temperature (T m ) and thermal degradation temperature of the composites were not affected by the addition of CF, whereas the crystallization temperature (T c ) was affected by the addition of CFs.
    No preview · Article · Nov 2014 · Fibers and Polymers
  • Hyung Jin Choi · Jung Soo Kim

    No preview · Article · Sep 2014
  • Jung Soo Kim · Ji-Hoon Jang · Dong-Gyu Jeon · Dong Hyun Kim

    No preview · Article · Sep 2014

  • No preview · Article · Sep 2014

Publication Stats

1k Citations
176.14 Total Impact Points

Institutions

  • 2015
    • Kyungpook National University Hospital
      Sŏul, Seoul, South Korea
  • 2014-2015
    • Sungkyunkwan University
      Sŏul, Seoul, South Korea
    • Korea Environmental Industry and Technology Institute
      Sŏul, Seoul, South Korea
  • 2010-2015
    • Inje University Paik Hospital
      • Department of Neurosurgery
      Sŏul, Seoul, South Korea
    • Korea University
      • Department of Electrical Engineering
      Sŏul, Seoul, South Korea
    • University of Florida
      Gainesville, Florida, United States
    • Korea Research Institute of Chemical Technology
      • Division of Drug Discovery Research
      Daiden, Daejeon, South Korea
  • 2003-2015
    • Hanyang University
      • Division of Chemical Engineering and Bioengineering
      Sŏul, Seoul, South Korea
    • Korea Atomic Energy Research Institute (KAERI)
      Daiden, Daejeon, South Korea
    • Pohang University of Science and Technology
      • Department of Mathematics
      Geijitsu, North Gyeongsang, South Korea
  • 1991-2015
    • Chonbuk National University
      • School of Medicine
      Tsiuentcheou, Jeollabuk-do, South Korea
  • 2013-2014
    • Inje University
      Kŭmhae, Gyeongsangnam-do, South Korea
    • Korea Institute of Industrial Technology
      안산시, Gyeonggi-do, South Korea
  • 2010-2013
    • Chonbuk National University Hospital
      Sŏul, Seoul, South Korea
  • 2006-2013
    • Kyungpook National University
      • School of Medicine
      Daikyū, Daegu, South Korea
  • 2012
    • William Penn University
      Worcester, Massachusetts, United States
    • Pusan National University
      Busan, Busan, South Korea
    • University of Michigan
      Ann Arbor, Michigan, United States
    • Yeungnam University
      • College of Medicine
      Daikyū, Daegu, South Korea
  • 2006-2010
    • Seoul National University
      • • Department of Biomedical Engineering
      • • Medical Research Center
      Sŏul, Seoul, South Korea
  • 2009
    • Korea Medical Research Institute
      Sŏul, Seoul, South Korea
    • Catholic University of Korea
      • College of Medicine
      Sŏul, Seoul, South Korea
  • 2008-2009
    • Korea Institute of Nuclear Nonproliferation and Control
      Sŏul, Seoul, South Korea
    • Pennsylvania State University
      • • Department of Aerospace Engineering
      • • Department of Electrical Engineering
      University Park, Maryland, United States
  • 2000-2007
    • Hongik University
      • • Department of Mechanical and System Design Engineering
      • • College of Engineering
      Sŏul, Seoul, South Korea
  • 1989-2006
    • Yonsei University
      • • Department of Food and Nutrition
      • • Department of Physics
      Sŏul, Seoul, South Korea
  • 2005
    • University of Ulsan
      • Department of Laboratory Medicine
      Ulsan, Ulsan, South Korea
  • 2000-2001
    • Hong-ik university
      CDC, Utah, United States
  • 1999
    • Electronics and Telecommunications Research Institute
      Sŏul, Seoul, South Korea