Mohammad H Bozorgmehrifard

Islamic Azad University Tehran Science and Research Branch, Teheran, Tehrān, Iran

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Publications (4)0.79 Total impact

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    Full-text · Dataset · Aug 2013
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    ABSTRACT: Avian infectious bronchitis virus (IBV) is prevalent in all countries with intensive poultry flocks. This disease is characterised primarily by respiratory signs, but some IBV strains may also infect other organs such as the intestinal and urogenital tracts. The aim of this study was to characterise the histopathological lesions and tissue tropism of Iranian isolate IR/773/2001(793/B) of avian infectious bronchitis virus in different organs of experimentally infected SPF chickens. Forty-two one-day-old, specific pathogen-free (SPF) chicks were divided randomly into two groups (21 chicks to each group). At the age of 12 days, one group was inoculated intra-ocularly with 103 EID50 of the 793/B isolate, and the other was kept as the control group. Tissue samples were collected at 2, 4, 6, 8, 10 and 12 days post-inoculation (PI). The IBV virus was detected in the caecal tonsils and cloaca from the 2nd to the 12th day PI. The virus was also detected in the kidneys from days 4-10 PI and in the bursa of Fabricius from days 4-12 PI. The virus was detected in the trachea, lungs and thymus. The most obvious histopathological lesions were found in the trachea, kidney, lungs and bursa of Fabricius. Amongst the lymphoid tissues, histopathological changes were found most frequently in the bursa of Fabricius. The results of this study indicated that the 793/B serotype of IBV is unlikely to cause mortality, severe clinical signs or gross lesions in infected chickens, but its replication in some tissues including the bursa of Fabricius could render birds susceptible to other micro-organisms.
    Full-text · Article · May 2013 · Journal of the South African Veterinary Association
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    ABSTRACT: Avian infectious bronchitis virus (IBV) is prevalent in all countries with intensive poultry flocks. This disease is characterised primarily by respiratory signs, but some IBV strains may also infect other organs such as the intestinal and urogenital tracts. The aim of this study was to characterise the histopathological lesions and tissue tropism of Iranian isolate IR/773/2001(793/B) of avian infectious bronchitis virus in different organs of experimentally infected SPF chickens. Forty-two one-day-old, specific pathogen-free (SPF) chicks were divided randomly into two groups (21 chicks to each group). At the age of 12 days, one group was inoculated intra-ocularly with 10 3 EID 50 of the 793/B isolate, and the other was kept as the control group. Tissue samples were collected at 2, 4, 6, 8, 10 and 12 days post-inoculation (PI). The IBV virus was detected in the caecal tonsils and cloaca from the 2nd to the 12th day PI. The virus was also detected in the kidneys from days 4–10 PI and in the bursa of Fabricius from days 4–12 PI. The virus was detected in the trachea, lungs and thymus. The most obvious histopathological lesions were found in the trachea, kidney, lungs and bursa of Fabricius. Amongst the lymphoid tissues, histopathological changes were found most frequently in the bursa of Fabricius. The results of this study indicated that the 793/B serotype of IBV is unlikely to cause mortality, severe clinical signs or gross lesions in infected chickens, but its replication in some tissues including the bursa of Fabricius could render birds susceptible to other micro-organisms.
    Full-text · Article · May 2013 · Journal of the South African Veterinary Medical Association
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    Bozorgmehrifard M. H · Feizi A · Bijanzad P
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    ABSTRACT: Newcastle disease is one of the most important causes of economic losses in the poultry production and can be resulted in high mortality. Antibody detection is also an important tool for assessment of the immunity against the disease. In the present study a trial was conducted to evaluate the effect of an immune stimulator (Echinacea purpurea) on antibody production against Newcastle disease vaccine. 450 one day old broiler chicks were divide into five groups of three repeat each. For three weeks from day one various doses of Echinacea purpurea extract was prescribed to four treatment groups and to the fifth group placebo in water was prescribed. All groups were vaccinated on days:11, 19, 38. Subsequently, serum samples were collected at days 10, 25, 34, 52 of post vaccination from 21 chicks of each group (4 samples of each repeat) and were tested for Newcastle antibody titers by HI test. This experiment showed that the use of Echinacea purpurea extract with the rate of 29, 75 Mg per kilo body weight per day had better effects on antibody titre and significantly increased between control group and treatment groups (p<0.01). It is also revealed that the use of Echinacea purpurea induces FCR improvement and mortality rate was decreased significantly (p<0.01).
    Full-text · Article · Aug 2010

Publication Stats

4 Citations
0.79 Total Impact Points

Institutions

  • 2013
    • Islamic Azad University Tehran Science and Research Branch
      Teheran, Tehrān, Iran
    • Islamic Azad University
      • Department of Poultry Diseases
      Teheran, Tehrān, Iran
  • 2010
    • University of Tehran
      • Department of Clinical Sciences
      Teheran, Tehrān, Iran