[Show abstract][Hide abstract] ABSTRACT: Blood samples were collected from Gadaba, a tribal population of Andhra Pradesh, South India, in order to examine the distribution of blood groups, red cell enzymes and the gammaglobulin polymorphism. Out of 20 genetic markers studied seven protein loci exhibited monomorphism. Surprisingly a case of a rare homozygous variant and twenty-one heterozygous variants at the phosphogluconate dehydrogenase locus (6-PGD), six variants at the phosphohexose isomerase locus (PHI) and a single case of phosphoglucomutase locus 1 (PGM 1) variant were observed. Further, the tribal populations of South India reveal higher frequencies of rare variants than the caste populations. However, the presence of rare variants that are phenotypically neutral may be plausibly due to their high selective value.
No preview · Article · Apr 1999 · Anthropologischer Anzeiger
[Show abstract][Hide abstract] ABSTRACT: A total of 998 unrelated individuals from the Gadaba tribal population of Andhra Pradesh, South India, were screened for red cell phosphohexose isomerase (PHI) by starch gel electrophoresis. A new and hitherto for Andhra Pradesh not yet reported rare variant phenotype was observed: PHI 6-1. The new allele is designated as PHI*6Gadaba.
No preview · Article · Jan 1997 · Anthropologischer Anzeiger
[Show abstract][Hide abstract] ABSTRACT: Blood samples from 1000 unrelated, adult individuals of the Gadaba tribal population were screened for 6-phosphogluconate dehydrogenase. We report the occurrence of a new fast moving variant, which is caused by the allele PGD* Gadaba. This allele is reported for the first time among the tribal populations of Andhra Pradesh. Its frequency comes to 0.0115, and it was observed in heterozygous (2.10%) and homozygous (0.10%) conditions.
No preview · Article · Jan 1996 · Anthropologischer Anzeiger