Eun Young Yoo

Yonsei University, Sŏul, Seoul, South Korea

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Publications (26)34.99 Total impact

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    ABSTRACT: The present cross-sectional study tested a hypothetical path model consisting of psychosocial factors in relation to activity participation restriction in chronic stroke. Motor and cognitive functions and age; psychological factors consisting of depressive symptoms, hopeful thinking, and self-esteem; and activities of daily living and social support served as psychosocial factors. Data were collected from 171 community-dwelling individuals with chronic stroke in Korea. Path analysis was conducted to test the model fit between the obtained data and the hypothetical model to examine the direct and indirect effects of variables on participation restriction. Among the psychosocial factors, psychological factors and activities of daily living played the most significant role in predicting the degree of participation restriction, as well as mediating the relationship. Motor and cognitive functions were mediated by activities of daily living, and social support was mediated by psychological factors to affect participation restriction. Among the psychological factors, hopeful thinking exhibited the strongest relationship. To increase stroke survivors' participation during the course of rehabilitation, psychosocial factors as well as biological factors should be included in a multidimensional treatment approach. (PsycINFO Database Record (c) 2015 APA, all rights reserved).
    No preview · Article · Jul 2015 · Rehabilitation Psychology
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    ABSTRACT: The aim of this study was to identify the correlation between the Mann Assessment of Swallowing Ability (MASA) and the Videofluoroscopic Dysphagia Scale (VDS) to investigate the applicability of the MASA as a follow-up test of swallowing function. Criterion validity was assessed for MASA results versus VDS scores of tests administered to 54 patients who had a stroke and dysphagia. A significant correlation was found between the MASA and the VDS (correlation coefficient = -0.509). In analyses of test-re-test reliability and inter-rater reliability of the scoring scale, intraclass correlation coefficients (2, 1) were high (0.98, 0.99). In conclusion, the results of the present study indicate that the MASA holds adequate clinical test-re-test and inter-rater reliabilities and criterion validity for measuring the swallowing abilities of Korean patients who had a stroke and dysphagia. The MASA could contribute to more systematic management of swallowing problems and efficient therapeutic service. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.
    No preview · Article · May 2015 · Occupational Therapy International

  • No preview · Article · Mar 2015
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    ABSTRACT: To investigate the detectability and imaging characteristics of primary tumors according to imaging modalities and to identify clinical features and histological prognostic factors for axillary metastases in patients with small (≤1cm, T1a and T1b) invasive breast cancer. A total of 221 patients with histologically confirmed small invasive cancers were included for the statistical analysis. At mammography, ultrasonography and MRI, the detectability, and imaging characteristics of primary tumors were compared in patients with or without axillary metastases. Clinical features and histological prognostic factors for axillary metastases were investigated. Of 221 patients examined, axillary metastasis was found in 42 (19%) at the time of surgery. There was no significant difference in detectability of small tumors using ultrasonography and MRI between patients with and without axillary metastasis. However, mammography had a higher positive rate of primary tumors in patients with axillary metastasis than without metastasis (92.9% vs. 77.1%, p=0.023). Patients with axillary metastasis in small cancers showed more common architectural distortion than negative (p=0.0147) or mass (p=0.0356) on mammography. Clinical features were not different in the two groups. Only lymphovascular invasion was independently associated with axillary metastasis (p=0.0051, 95% CI, 1.527-11.597). The detectability of small invasive breast cancers among patients with and without axillary metastasis is different with mammography, but not with US and MRI. Lymphovascular invasion is only a predictor for axillary metastasis in small invasive cancers.
    No preview · Article · Jul 2013 · European journal of radiology
  • Eun Young Yoo · Jung Hee Shin · Eun Young Ko · Boo-Kyung Han
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    ABSTRACT: The aim of this study was to evaluate the diagnostic contribution of BRAF(V600E) mutation analysis from the fine-needle aspiration (FNA) specimens of calcified thyroid nodules. From January 2008 to December 2008, 139 patients with 139 calcified thyroid nodules prospectively underwent BRAF(V600E) mutation analysis and ultrasound-guided FNA. At ultrasound, the patterns of calcification were classified into microcalcification, macrocalcification, and rim calcification. The performance of FNA alone then FNA plus BRAF(V600E) mutation analysis for the diagnosis of calcified thyroid nodules was compared on the basis of surgery, repeated FNA, or imaging follow-up for at least 1 year. Of 139 calcified nodules, 92 (66%) malignancies were detected, which included 91 papillary thyroid carcinomas and one follicular thyroid carcinoma. The malignant rates based on calcification type were 80% (63 of 79) for microcalcifications, 59% (19 of 32) for macrocalcifications, and 36% (10 of 28) for rim calcifications. The BRAF(V600E) mutation was identified in 50% of all nodules and in five (25%) of 20 nodules with indeterminate or nondiagnostic cytology. Adding BRAF(V600E) mutation analysis to FNA compared with FNA alone improved the negative predictive value of 83.9 to 92.2% (p = 0.034) but not the sensitivity, specificity, positive predictive value, and accuracy. The BRAF(V600E) mutation analysis from FNA specimens for calcified thyroid nodules may be performed for a greater negative predictive value and unveil the malignancy in 25% of indeterminate or nondiagnostic cytology.
    No preview · Article · Apr 2012 · American Journal of Roentgenology
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    ABSTRACT: Frailty is considered to be a clinical syndrome characterized by decreased physiological reserves associated with a greater risk of health-related problems, hospitalization, and death. The current study examined hospitalization, falls, cognitive decline and disability between robust, prefrail and frail elderly in one year. 110 participants aged 65 or more who visited two senior welfare centers in Seoul from February 2008 to June 2008 were surveyed again from March 2009 to June 2009 with demographic characteristics, number of chronic diseases and medication, study of osteoporotic fractures (SOF) frailty index, instrumental activity of daily living (IADL), depression, mini-mental state examination-Korean version (MMSE-K), falling history and admission history within one year. These results were compared with participants' previous survey done one year ago. Among total 110 subjects, 48 (44%) robust, 30 (27%) prefrail, and 32 (29%) frail subjects changed to 26 (24%), 54 (49%), and 30 (27%) respectively over the year. There were statistical significances in age, number of chronic disease, depressive mood, MMSE, falls, hospitalization, IADL disability contributing to frailty (P < 0.05). Frailty defined by SOF frailty index was associated with greater risk of adverse outcomes. Frail subjects had a higher age-adjusted risk of cognitive function decline (odds ratio [OR], 3.57), disability (OR, 9.64), fall (OR, 5.42), and hospitalization (OR, 4.45; P < 0.005). The frailty index like SOF frailty index might predict risk of falls, disability, hospitalization, and cognitive decline in the elderly, emphasizing special attention to the individuals showing frailty in outpatient examination.
    Full-text · Article · May 2011
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    ABSTRACT: PURPOSE To evaluate the diagnostic accuracy of preoperative imaging methods and physical examination for predicting co-existing invasive lesion in percutaneous biopsy-proven ductal carcinoma in situ (DCIS) patients METHOD AND MATERIALS We analyzed preoperative mammography, ultrasound (US), and MR findings of percutaneous biopsy-proven DCIS in 77 patients. Two radiologists, who were blinded to the final pathologic results, retrospectively reviewed the preoperative images. Presence of mass- forming area on US, and presence of mass or focal asymmetry on mammography were evaluated. Co-existing invasive lesion was considered on MRI when the lesion showed extent equal or more than 4cm, or early enhancement and wash out kinetics. Palpability of the lesion was evaluated based on the clinical records of physical examination by physician. We evaluated the diagnostic accuracy, sensitivity, specificity, PPV, and NPV of the findings of different imaging modalities, and physical examination for predicting invasive carcinoma. RESULTS Final pathology after definite surgery was DCIS with invasive carcinoma in 27 patients and pure DCIS in 50 patients. Mammography showed mass or density in 28/77 patients, US showed mass-forming area in 40/77 patients. Positive MR finding for co-existing invasive lesion was found in 45/77 patients, and 26/77 lesions were palpable on physical examination. The diagnostic accuracy of mammography, US, MRI, and physical examination for predicting invasive lesion was 51.9%, 36.4%, 71.4%, and 57.1% respectively. MRI showed best performance with 92.6% sensitivity, 61.2% specificity, 56.8% PPV, and 93.8% NPV. Physical examination was next to MRI with 44.4% sensitivity, 72.0% specificity, 46.2% PPV, 70.6% NPV. US showed worst performance with 48.1% sensitivity, 46.0% specificity, 32.5% PPV, and 62.2% NPV. CONCLUSION MRI showed best diagnostic performance and accuracy in predicting co-existing invasive carcinoma in percutaneous biopsy-proven DCIS patients. CLINICAL RELEVANCE/APPLICATION In the patients with percutaneous biopsy-proven DCIS, preoperative MRI would be the best tool for predicting co-existent invasive lesions.
    No preview · Conference Paper · Dec 2010
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    ABSTRACT: PURPOSE The aim of this study was to determine whether radiofrequency ablation with superficial saline injection can minimize thermal injury of skin without the influence of therapeutic efficacy. METHOD AND MATERIALS Twelve percutaneous RF ablation procedures were performed in the thighs of 6 rabbits (control, n=6, right thigh; experimental, n=6, left thigh) using an internally cooled electrode with 1 cm active tip. The ablation was performed in the most superficial area of thigh muscle. In the experimental group, saline with 1 cc in amount before ablation was injected at the tissue layer between skin and ablated muscle. The duration and energy for ablation were the same in the control and the experimental group. Rabbits were sacrificed 2 days after ablation and were compared for gross skin state and histopathological findings after ablation. RESULTS The degree of thermal coagulation of the muscle was similar in both groups at pathology. Grossly, skin redness was mild in the experimental group but moderate in the control group. Of 6 rabbits, five showed more frequently histopathological changes including inflammatory reaction, interruption of collagen fibers, injury of skin adnexa and fibrosis in the control group compared to experimental group. However, there was no difference in changes between two groups in one. One rabbit with a higher energy had the partially dissected epidermis only in the control group. CONCLUSION Radiofrequency ablation with superficial saline injection can prevent skin burn and provide equivalent therapeutic efficacy for ablating superficial lesions. CLINICAL RELEVANCE/APPLICATION Radiofrequency ablation for benign thyroid tumors with cosmetic problem is indicated, but it is important to avoid skin burn during the ablation of superficial lesion.
    No preview · Conference Paper · Dec 2010
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    ABSTRACT: PURPOSE To investigate whether adding diffusion-weighted imaging (DWI) to dynamic contrast-enhanced MRI (DCE-MRI) could provide diagnostic information on residual breast cancers following neoadjuvant chemotherapy. METHOD AND MATERIALS From July 2008 to December 2009, 78 patients underwent breast MRI with DWI (3T MRI n=50, 1.5T n=28) following neoadjuvant chemotherapy. DWIs were performed with b-value (sec/mm2) 0, 750 at 1.5T, and 0, 800 or 1000 at 3T MRI. Two radiologists retrospectively reviewed the detectability and size of the residual tumor on DCE-MRI, DWI, and DCE-MRI plus DWI with time interval without knowledge of pathological results. Apparent diffusion coefficient (ADC) values were also assessed. The presence of residual tumor and tumor size were compared with pathology. The reliability was analyzed for DCE-MRI or DWI alone and DCE-MRI plus DWI for the same set of the lesion using Intraclass Correlation Coefficient (ICC). RESULTS Of the 78 patients, 58 had residual cancer and 20 had no residual lesion. Detectability of the residual cancer was higher on DWI than DCE-MRI (ICC 0.6489, p<0.0001 vs. 0.5496, p=0.0003). DCE-MRI plus DWI was more reliable sequences for evaluating residual cancer than DWI or DCE-MRI alone (ICC 0.7162, p=<0.0001). The size of residual tumor was more accurate on DCE-MRI plus DWI than DWI or DCE-MRI alone (ICC 0.8907 vs. 0.7728 vs. 0.7918, p<0.0001). ADC value showed no significant difference between residual cancer and fibrotic changes (p=0.13). CONCLUSION The adjunct use of DWI to DCE-MRI for evaluating residual breast cancer improved the diagnostic performance in patients with breast cancer following neoadjuvant chemotherapy. CLINICAL RELEVANCE/APPLICATION DWI shows potential for improving the detectability and accuracy of estimating residual tumor size following neoadjuvant chemotherapy as an adjunct to DCE-MRI.
    No preview · Conference Paper · Dec 2010
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    ABSTRACT: Myofibroblastoma (MFB) of the breast was coined by Wargotz et al(1) in 1987 to describe benign spindle cell tumors of the breast with myofibroblastic features. There has been only 1 report about mammographic and sonographic findings of MFB of the female breast.(2) We report a case of a pathologically diagnosed breast MFB in a female patient and describe the imaging characteristics, including mammography, sonography, and magnetic resonance imaging (MRI). We also discuss other breast diseases that can be included in the differential diagnosis with MFB from a radiologic point of view.
    No preview · Article · Dec 2010 · Journal of ultrasound in medicine: official journal of the American Institute of Ultrasound in Medicine
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    ABSTRACT: OBJECTIVE: The purpose of this study was to correlate findings on the first follow-up CT after treatment with imatinib in patients with residual or recurrent gastrointestinal stromal tumors (GISTs) with the different types of KIT mutation present at initial resection. CONCLUSION: Residual and recurrent GISTs with KIT mutation of exon 11 deletion more frequently showed both tumor shrinkage and cystic change on 2-month follow-up CT images after the start of imatinib treatment than did other mutation types.
    No preview · Article · Sep 2009 · American Journal of Roentgenology
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    ABSTRACT: Recent liver multi-detector row computed tomography (MDCT) always covers the distal esophagus with an excellent image quality. The aim of this study was to compare the performance of faculty abdominal radiologists with those of radiology residents and endoscopists for the detection of esophageal varices and high-risk esophageal varices on liver MDCT. A total of 104 cirrhotic patients that had undergone liver MDCT 4 weeks or less before an upper endoscopy were evaluated. Two faculty abdominal radiologists, two radiology residents, and two endoscopists independently interpreted all of the CT images to detect the presence of esophageal varices and high-risk (grade 2 or 3) esophageal varices. With endoscopic grading as the reference standard, their performances were compared by using receiver operating characteristic (ROC) curve analysis. The areas under the ROC curves for the detection of esophageal varices indicated better performance of the abdominal radiologists (A(z) = 0.868), compared with the radiology residents (A(z) = 0.798) (P = 0.007) and endoscopists (A(z) = 0.784) (P = 0.006). For the detection of high-risk esophageal varices, however, the performance of the abdominal radiologists (A(z) = 0.914) was similar to those of radiology residents (A(z) = 0.900) and endoscopists (A(z) = 0.907) (each P > 0.05). Experienced readers have a better ability to detect esophageal varices on liver MDCT, but had no higher performance to evaluate high-risk esophageal varices. As the accuracy of detecting high-risk esophageal varices with clinical relevance on liver MDCT is excellent, even by endoscopists, the evaluation of esophageal varices from a recent liver MDCT may be useful to avoid the use of low-yield endoscopy.
    No preview · Article · Apr 2009 · Journal of Gastroenterology and Hepatology
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    ABSTRACT: The standard one-on-one constraint-induced movement therapy (CIMT) recently gained widespread acceptance as a means of effective stroke rehabilitation, but inherent issues associated with cost-effectiveness, safety, lack of dynamic group interaction, and compliance hampered this novel approach. This preliminary study highlights the effect of the group community-based CIMT, which integrated the concepts of the standard CIMT regimen. Eight participants were recruited from a local city community center and trained in the usage of mittens and safety management on the affected upper extremity for 90% of the hours when awake. The community-based CIMT was provided for 2 hours a day over 10 days. Outcome measures include motor recovery, strength, amount of use and quality of movement, self-perceived occupational performance and satisfaction as well as other psychological factors such as motivation, compliance, and enjoyment. These results all showed significant improvement after intervention and were maintained even after the 6-month follow up (P<0.05).
    No preview · Article · Jan 2009
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    ABSTRACT: The aim of this paper was to investigate the effectiveness of client-centred occupational therapy using the Canadian Occupational Performance Measure (COPM) and the Assessment of Motor and Process Skills (AMPS). Eight girls and 23 boys from Korea, with developmental disabilities and from 3 to 10 years of age participated in this study. Each child participated in 20 to 24 sessions of client-centred occupational therapy. Both the COPM and the AMPS change scores demonstrated statistically significant improvement (p < 0.01) in occupational performance. Significant correlations were found between COPM - Performance and AMPS - Motor skills (r(s) = 0.64, p < 0.05), and COPM - Satisfaction and AMPS - Process skills (r(s) = 0.62, p < 0.05) in a group positive towards client-centred occupational therapy. The COPM was a valuable tool in guiding and measuring the client-centred occupational therapy for children with developmental disabilities. The small sample size of 31 children limits the generalizability of the study's results. Future research needs to use a larger and more diverse sample of children to further validate the effectiveness of client-centred occupational therapy.
    No preview · Article · Dec 2008 · Occupational Therapy International
  • Eun Young Yoo · Eun Young Ko · Won Jae Lee · Jae Hoon Im · So Young Yoo
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    ABSTRACT: To evaluate the role and difficulties of the use of routine abdomen ultrasound (US) in postoperative breast cancer patients.
    No preview · Article · Jan 2008
  • Eun Young Yoo · Kyung Soo Lee · Jeongho Han · Yoon Kyung Kim
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    ABSTRACT: Hamartomata is the most common benign type of tumor, occuring in the lung. However, a cystic pulmonary hamartoma is extremely rare, and is difficult to diagnose due to its nonspecific nature. We report a case of cystic pulmonary hamartoma in which a popcorn-like calcification is clearly identified, thus enabling a confident diagnosis of the disease.
    No preview · Article · Jan 2008
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    ABSTRACT: We wanted to evaluate the short-term effects of balloon-occluded retrograde transvenous obliteration (BRTO) for treating gastric variceal bleeding, in terms of the portal hypertensive changes, by comparing CT scans. We enrolled 27 patients who underwent BRTO for gastric variceal bleeding and they had CT scans performed just before and after BRTO. The pre- and post-procedural CT scans were retrospectively compared by two radiologists working in consensus to evaluate the short-term effects of BRTO on the subsequent portal hypertensive changes, including ascites, splenomegaly, portosystemic collaterals (other than gastrorenal shunt), the gall bladder (GB) edema and the intestinal wall edema. Statistical differences were analyzed using the Wilcoxon signed rank test and the paired t-test. Following BRTO, ascites developed or was aggravated in 22 (82%) of 27 patients and it was improved in two patients; the median spleen volumes increased from 438.2 cm(3) to 580.8 cm(3), and based on a 15% volume change cut-off value, splenic enlargement occurred in 15 (56%) of the 27 patients. The development of new collaterals or worsening of existing collaterals was not observed in any patient. GB wall edema developed or was aggravated in four of 23 patients and this disappeared or improved in five; intestinal wall edema developed or was aggravated in nine of 27 patients, and this disappeared or improved in five. Statistically, we found significant differences for ascites and the splenic volumes before and after BRTO (p = 0.001 and p < 0.001, respectively) Some portal hypertensive changes, including ascites and splenomegaly, can be aggravated shortly after BRTO.
    Preview · Article · Dec 2007 · Korean Journal of Radiology
  • Min Ye Jung · Keun Ho Lee · Eun Young Yoo · Joshua H. You
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    ABSTRACT: Introduction: Despite the important contribution of multifaceted risk factors on low back pain (LBP), only few studies have attempted to examine the impact of functional level and environmental factors on LBP in mothers of children with disabilities. Moreover, there has been no previous study investigating the risk factors associated with LBP in mothers of children with cerebral palsy. Hence, the present study was to investigate the risk factors associated with LBP in mothers of children with cerebral palsy.Patients and methods: A sample of 94 mothers of children attending three pediatric physical medicine and rehabilitation clinics at three major medical centers and local community rehabilitation centers for their rehabilitation services were recruited for this study. They were divided into two groups: group 1 (mothers of children with the Functional Independent Measure for Children [WeeFIM] score ? 5); and group 2 (mothers of children with WeeFIM score < 5). The independent variables included demographic characteristics of mothers and children, and functional independence levels in children with cerebral palsy as determined by the WeeFIM measurement. The dependent variables entailed level of pain and disability, which were determined by the Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI), respectively. Multiple regression analysis, one-way analysis of variance (ANOVA), independent t-test, and frequency analysis statistics were performed at P < 0.05.Results: The most important risk factors associated with LBP in the care-giving mothers were type of housing, weight, and locomotion of the children in this order (P < 0.05). The regression equation for locomotion measure was significant (R2 = 0.22; F [3, 94] = 7.43; P = 0.002). The regression equation for weight measure was significant (R2 = 0.22; F [3, 94] = 7.43; P = 0.0 06). The regression equation for the type of housing measure was significant (R2 = 0.22; F [3, 94] = 7.43; p = 0.025). ANOVA revealed that mothers living in multi-unit villas complained of significantly greater pain when compared to the other types of housing (P = 0.037). Independent t-test showed that the group of children who required physical assistance from their mothers for transfer (P = 0.000), locomotion (P = 0.005) and overall WeeFIM score (P = 0.029) showed greater pain in NRS when compared with the controls who did not require physical assistance. Pearson correlation showed that LBP pain in NRS was correlated with the children's transfer (r = ?0.23; P < 0.05), locomotion (r = ?0.24; P < 0.01), and weight (r = 0.27; P < 0.01) variables, respectively. Frequency analysis of the home environmental factors showed that mothers' care and independence of children in the home were affected by access to the bathroom, entrance, kitchen, and corridors. Adaptive devices that influenced children's independence were in self-care, sphincter control, and locomotion, followed by transfer.
    No preview · Article · May 2007 · The Pain Clinic
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    ABSTRACT: Using proteomic analysis including 2-DE, image analysis, and protein identification with LC-MS/MS, an investigation aimed at a better understanding of the differentially expressed proteins and/or gene products was carried out with total cell extracts from placental tissues in nonpungent (Capsicum annuum cv. Saeng-Ryeog #213) and pungent peppers (C. annuum cv. Saeng-Ryeog #211). Mobilization of the most abundant proteins, which were on the gels of pH ranges of 4-7, 4.5-5.5, 5.5-6.7, and 6-9, and showed very similar profiles in the two tissues, revealing approximately 2600 protein spots consisting of 1200 on pH 4-7, 600 on 4.5-5.5, 550 on 5.5-6.7, 250 on 6-9. Of these, 37 protein spots, which appeared in only pungent tissues but not in nonpungent tissues or markedly increased in their staining intensities on the gels from pungent tissue, were selected, excised, in-gel trypsin digested, and analyzed by LC-ESI-MS/MS. Peptide MS/MS data were searched against publicly available protein and EST databases, and 22 proteins were identified. Based on this result, we tested and compared the differential expression during fruit development on the 2-DE gels with total cell extracts from placental tissues of pungent and nonpungent peppers at an interval of 10 days from 10 to 40 days after flowering. In addition, this differential protein expression was further confirmed for some subsets of candidates by Northern-blot analysis with RNA samples from placental tissues harvested from each pepper fruit at the same sampling intervals. In this study, the physiological implications, revealed from the experimental data in the levels of proteome and transcripts, are discussed in the context of a complex biosynthesis network of capsaicinoids in pepper cells responsive to pungency.
    Full-text · Article · Oct 2006 · PROTEOMICS
  • Duck Won Oh · Eun Young Yoo · Chung Hwi Yi · Oh Yun Kwon

    No preview · Article · Sep 2005 · Physiotherapy Research International

Publication Stats

285 Citations
34.99 Total Impact Points

Institutions

  • 2005-2015
    • Yonsei University
      • College of Health Sciences
      Sŏul, Seoul, South Korea
  • 2007-2013
    • Sungkyunkwan University
      • Department of Radiology
      Sŏul, Seoul, South Korea
  • 2011
    • Hallym University Medical Center
      • Department of Family Medicine
      Seoul, Seoul, South Korea
  • 2003-2006
    • Seoul National University
      • • Department of Plant Science
      • • Center for Plant Molecular Genetics and Breeding Research
      Sŏul, Seoul, South Korea