Cavit Kart

Karadeniz Technical University, Atrabazandah, Trabzon, Turkey

Are you Cavit Kart?

Claim your profile

Publications (23)46.03 Total impact

  • C Kart · S Guven · E Guvendag güven

    No preview · Article · Nov 2015 · Journal of Minimally Invasive Gynecology

  • No preview · Article · Nov 2015 · Journal of Minimally Invasive Gynecology
  • [Show abstract] [Hide abstract]
    ABSTRACT: Aim: The aim of this study is to evaluate the diagnostic value of serum oxidative stress marker levels (ischemia-modified albumin, IMA; malondialdehyde, MDA) and total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) levels that occur in ovarian torsion and to determine the threshold value of these markers in the diagnosis of ovarian torsion. Methods: In this prospective case-control study, 34 women (the study group) with acute pelvic pain (20 with and 14 without ovarian torsion) and 40 control subjects were included. The diagnosis of ovarian torsion was confirmed with laparoscopy in all cases. Preoperative serum samples were collected in the study group. Serum oxidative stress marker levels (IMA and MDA) and TOS, TAS and OSI levels were measured. Results: Serum MDA, TOS and IMA concentrations were significantly higher in women with ovarian torsion than in the healthy control group. However, serum TAS, TOS and OSI concentrations were significantly higher in women without ovarian torsion than within the healthy control group. Only IMA significantly distinguished patients with or without ovarian torsion. The best IMA value, according to the receiver operating characteristic curve, was 0.7045 absorbance units, with 90.00% sensitivity and 92.31% specificity. The patients in the ovarian torsion group had significantly lower serum TAS and OSI levels compared with patients without ovarian torsion. Conclusion: The elevated serum IMA levels with high sensitivity-specificity values observed in women with ovarian torsion seem to have a potential role as a serum marker in the preoperative diagnosis of ovarian torsion in emergency settings.
    No preview · Article · Jan 2015 · Gynecologic and Obstetric Investigation
  • [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this study is to evaluate the performance of amniotic fluid lamellar body count (LBC) on the timing of elective caesarean delivery (CS) at ≥ 39 weeks. After allocating the study group (group I, transient tachypnoea of newborn (TTN), n = 14), an age-matched control group (group II, no TTN, n = 79) was selected for amniotic fluid LBC analysis. The median amniotic fluid LBC levels in group I were significantly lower than in the control group. Furthermore, the median values of mean lamellar body volume, median lamellar body distribution width and lamellar bodycrit in group I were also significantly lower than in group II. The best amniotic fluid LBC value to predict TTN was 40.15 × 103/μl, with 82.3% sensitivity and 64.3% specificity. The favourable sensitivity and specificity values to predict the TTN for amniotic fluid LBC may suggest using it as an elective caesarean delivery-time scheduling marker.
    No preview · Article · Nov 2014 · Journal of Obstetrics and Gynaecology
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To investigate the effect of endometrial injury on the clinical pregnancy rate in normoresponders undergoing long agonist protocol intracytoplasmic sperm injection (ICSI) cycles with single embryo transfer. Prospective case-control study. One hundred and eighteen women (age <35 years, normoresponders with Grade I or II embryos for transfer) were included. Women in the intervention group (n=56) underwent endometrial biopsy on Day 3 of the menstrual cycle following downregulation. Women in the control group (n=62) did not undergo endometrial biopsy. The clinical and embryological characteristics were comparable in the two groups, and no significant difference was found in the fertilization rates (66.32% in the intervention group vs 70.23% in the control group). The clinical pregnancy rate was 48.2% in the intervention group and 29.0% in the control group (p=0.025). Endometrial injury may increase the clinical pregnancy rate (odds ratio 2.27). The 'take home baby' rates were 33.9% and 17.7% in the intervention and control groups, respectively (p=0.035). Assisted reproductive technology treatment that is preceded by endometrial injury may increase the clinical pregnancy rate in women undergoing long agonist protocol ICSI cycles with single embryo transfer.
    Full-text · Article · Nov 2013 · European journal of obstetrics, gynecology, and reproductive biology
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To assess the impact of intramural fibroids on the intracytoplasmic sperm injection-embryo transfer (ICSI-ET) cycle outcome, when there is no compression of the endometrial cavity. In this retrospective, matched control study, the ICSI-ET outcome of sixty-two patients (Group I) with intramural fibroid (mean diameter <7 cm) and normal endometrial cavity demonstrated by office hysteroscopy was compared with matched-control group of patients (n = 301) with no fibroid (Group II). The diagnosis of fibroids was done by transvaginal ultrasonography. The mean age in fibroid group was 32.66 +/- 5.30 while this figure was 32.95 +/- 3.98 in control group. The clinical pregnancy rate was significantly lower in the fibroid group although fibroids not distorting the uterine cavity (25.8% vs. 39.9%, p = 0.04). In fibroid group the implantation rate was significantly lower than control group (20.97 +/- 37.93 vs.32.89 +/- 43.18%, p = 0.04). However, spontaneous abortion rate was higher in fibroid group but it did not reach the significant level (12.5% vs. 9.2%, p > 0.05). Women having intramural leiomyomas not encroaching on the uterine cavity have unfavorable ICSI/ET outcomes comparable to those of women without such leiomyomas. Therefore, myomectomy may be a good option for such patients with intramural fibroids even they do not have any endometrial distortion.
    Full-text · Article · Oct 2013 · Reproductive Biology and Endocrinology

  • No preview · Article · Sep 2013 · Fertility and Sterility

  • No preview · Article · Sep 2013 · Fertility and Sterility

  • No preview · Article · Mar 2013 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [Show abstract] [Hide abstract]
    ABSTRACT: To report the effect of oral contraceptives (OC) on cervical mucoprotein content by evaluating quantitatively mucoprotein 1 (MUC1), mucoprotein 2 (MUC2), mucoprotein 5AC (MUC5AC) and mucoprotein 5B (MUC5B) levels. This prospective controlled study included 20 women of reproductive age who had requested OC. Cervical mucus samples were obtained from the women before use of the OC and after 2 months of OC use. The mucus samples were then evaluated quantitatively for MUC1, MUC2, MUC5AC and MUC5B by ELISA by using specific antibodies. MUC5AC mucoprotein predominated quantitatively both before and after OC use. After OC use, compared to before OC use, variable increases in the levels of all studied mucoproteins were recorded, but the increases in MUC1, MUC2 and MUC5B were statistically significant. The difference in the level of MUC2 was remarkable (+54.36 ± 31.88 ng/mL). OC use may change the mucoprotein content (especially for MUC2) of cervical mucus and thus, may cause a highly viscous pattern of cervical mucus which may enhance the contraceptive efficacy of OC pills.
    No preview · Article · May 2012 · European journal of obstetrics, gynecology, and reproductive biology
  • [Show abstract] [Hide abstract]
    ABSTRACT: The prolongation, protraction or complete cessation of labor is called failed labor. It is one of the leading indications for cesarean delivery. The goal of this study was to measure pelvic floor muscle strength and investigate its effect on labor in nulliparous pregnant women. A total of 88 patients were included in the study. The study was conducted in nulliparous pregnant women with a low Bishop score (≤ 7). A low-dose intravenous oxytocin protocol was used for labor induction in all patients. Evaluation of pelvic floor muscle (PFM) strength was performed using a vaginal pressure measurement device just before labor induction. The duration of labor stages and the rate of failed labor were considered the main outcomes. The study group consisted of patients whose labor failed and who subsequently underwent cesarean delivery. The control group consisted of patients who delivered vaginally. The pelvic floor muscle strength and main outcome measures of the two groups were compared. No differences were found in age, weight, height, body mass index (BMI), and neonatal birth weight between the study and control groups. The mean resting and maximum squeeze pressures in the study group were 29.6 ± 9.8 and 56.4 ± 12.1 cm H(2)O respectively, significantly higher than in the control group. The best predictor of failed labor was a maximum squeeze pressure value of 59 cm H(2)0 (51.6% sensitivity and 87.7% specificity). Pelvic floor muscle strength appears to play a role in predicting failed labor.
    No preview · Article · Apr 2012 · International Urogynecology Journal

  • No preview · Article · Feb 2012 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [Show abstract] [Hide abstract]
    ABSTRACT: To investigate the effect of carbon dioxide pneumoperitoneum on systemic oxidative stress by using serum oxidative stress markers (ischemia modified albumin (IMA), malondialdehyde (MDA), total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI)) and to compare their effectiveness at clinically accepted safe intra-abdominal pressure levels (<12 mmHg). A total of 33 consecutive patients who had a unilateral ovarian cyst were enrolled for this prospective clinical study. All women underwent a laparoscopic ovarian cystectomy procedure. Venous blood was collected from patients preoperatively, 10 min after induction of anesthesia and 30 min after insufflation. Preoperative, 10(min), and 30(min) serum IMA, MDA, TOS, OSI and TAS levels were compared. The mean age was 29.3 ± 6.4 and the range of operation time was 45-80 min. The mean serum IMA levels showed a significant increase 30 min later from CO(2) insufflation (p<0.05). Significant alterations were not observed in serum MDA, TOS, OSI or TAS levels. Laparoscopic surgery causes systemic ischemia and this ischemic effect can be revealed by measuring serum ischemia modified albumin. IMA is more sensitive than MDA, TOS, OSI and TAS in early detection of systemic oxidative stress.
    No preview · Article · Dec 2011 · European journal of obstetrics, gynecology, and reproductive biology
  • [Show abstract] [Hide abstract]
    ABSTRACT: Purpose: Aim of the study was to investigate serum levels of total carnitine, arginine, asymmetric dimethylarginine (ADMA) and ischemia-modified albumin (IMA) and their combined use for the early detection of preeclampsia. Materials and Methods: The study group, which included normal pregnancies, consisted of a total of 44 singleton pregnant women (gestational age: between 6 and 12 weeks), divided into a preeclampsia group (n=22) and a control group (n=22). Results: When the serum levels of both groups in the 6th and 12th week of gestation were compared with levels between the 21st and 35th week of gestation, total carnitine, ADMA, IMA levels were increased; L-arginine levels were decreased in the preeclampsia group. Using a total carnitine level of 3.62nmol/ml as a cut-off value, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 68, 64, 65 and 64%; using an ADMA level of 518.70ng/ml as a cut-off value, the sensitivity, specificity, PPV and NPV were 82, 32, 55 and 64%; using an L-arginine level of 161.23nmol/ml as a cut-off value, the sensitivity, specificity, PPV and NPV were 45, 73, 62, 57%; using an IMA level of >0.82 as a cut-off value, the sensitivity, specificity, PPV and NPV were 45, 77, 64 and 57%, respectively. When all parameters were taken together to predict preeclampsia, the sensitivity, specificity, PPV and NPV were 9, 100, 100 and 52%, respectively. Conclusion: Although the sensitivity of ADMA levels was found to be higher in individual measurements, there is still no independent placental ischemia factor which can predict preeclampsia.
    No preview · Article · Sep 2011 · Geburtshilfe und Frauenheilkunde
  • Source
    Cavit Kart · Suleyman Guven · Turhan Aran · Hasan Dinc
    [Show abstract] [Hide abstract]
    ABSTRACT: To report the first case of massive intraabdominal hemorrhage after transvaginal ultrasonographically guided oocyte retrieval that was successfully managed with angiographic uterine artery embolization. Case report. Assisted reproduction unit of a tertiary university hospital. A 40-year-old woman with a history of primary infertility presented 10 days after oocyte retrieval because of severe abdominal pain, vomiting, and vaginal bleeding for 3 days. She had a history of mild factor VIII deficiency for 3 years. Evaluation of the intraabdominal hemorrhage with ultrasonography and angiography. Management of oocyte pickup complicated with intraabdominal hemorrhage. Treatment of massive life-threatening intraabdominal hemorrhage with bilateral uterine artery embolization. After transfusion with 2 units of fresh-frozen plasma and packed red blood cell, an interventional radiologist performed percutaneous transcatheter pelvic angiography to detect abnormal vascularization and vascular blush consistent with hemorrhage and then immediate bilateral uterine artery embolization was done. The patient was discharged from the hospital 5 days later without any remarkable complications. Angiographic uterine artery embolization under fluoroscopic guidance is a successful nonsurgical approach for the treatment of oocyte pickup-induced life-threatening hemorrhage.
    Preview · Article · Jun 2011 · Fertility and sterility
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Torsion of the ovary is a rare but serious cause of gynecologic surgical emergency. Specific laboratory markers that support the preoperative diagnosis of ovarian torsion are not currently available in the clinical routine. The aim of this study was to investigate the diagnostic value of plasma D-dimer level as an early indicator of ovarian torsion in an experimental rat ovarian torsion model. Sixteen female adult Sprague-Dawley rats were used for this controlled experimental study. Eight rats in the sham operation group (Group I) underwent a surgical procedure similar to Group II but the ovary was not occluded. In Group II (eight rats), a torsion model was created by using atraumatic vascular clips just above and below the right ovary for a 2-h period of ischemia. Right ovaries were surgically removed at the end of the procedure in each group. Blood was sampled before and after operation to assess plasma D-dimer levels. The main outcome measure was ovarian histopathologic findings scores and plasma D-dimer levels. There was no significant difference in pre-operative plasma D-dimer levels (0.5963 ± 0.2047 mg/l in Group I, 0.6344 ± 0.1348 mg/l in Group II, P = 0.815, Mann-Whitney U-test). However, mean plasma D-dimer value for Group II was significantly higher than that in the control group (1.2267 ± 0.3099 versus 0.6213 ± 0.2346 mg/l, respectively, Mann-Whitney U-test, P < 0.001), following 2 h of ovarian torsion. Ovarian tissue damage scores were also statistically significantly different among groups. If the observations made in a rat model are extended to humans, plasma D-dimer measurement may be a valuable parameter in the early diagnosis of ovarian torsion.
    Preview · Article · Mar 2011 · Human Reproduction
  • Cavit Kart · Turhan Aran · Suleyman Guven

    No preview · Article · Feb 2011 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Objective. Conjoined twin is a rarely seen congenital anomaly together with severe mortality and morbidity. The more common types of conjoined twins include the thoracopagus type, where the fusion is anterior, at the chest, and involves the heart. We are reporting one case of conjoined thoracopagus twins diagnosed by ultrasonography at 11 weeks. Case Report. In a multigravid pregnant woman who has been admitted to our clinic with a diagnosis of conjoined twins, thoracopagus, by ultrasonography at an 11-week gestation, termination of the pregnancy was performed. Conclusion. Making an early diagnosis with ultrasonographic examination gives the parents a chance to elect pregnancy termination.
    Preview · Article · Jan 2011 · ISRN obstetrics and gynecology

  • No preview · Article · Jan 2011
  • [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this study was to discuss the impact of electromagnetic field (EMF) on pregnancy under the light of current literature findings. Magnetic fields are ubiquitous in the modern society, and concerns have been expressed regarding possible adverse effects on pregnancy of these exposures. Although research on EMF fields has been performed for more than two decades, and the methodology and quality of studies have improved over time, there are still inadequate data for reproductive outcomes of affected mothers. Human data reviewed concern the potential pregnancy effects (mainly spontaneous abortions, low birthweight, preterm delivery, intrauterine growth restriction and congenital malformations) of exposure to sources of EMFs; maternal residence, electrically heated beds, occupational exposure (mainly video display terminals), and medical exposures. The available epidemiologic studies all have limitations that prevent to draw clearcut conclusions on the effects of EMFs on human reproduction. Although there are few case control studies reporting the association of adverse pregnancy outcomes and EMF exposure, most cohort and case-control studies have failed to show such risks. In conclusion, pregnant women should be aware of EMF sources, be informed about such harmful effects on pregnancy and keep her away of such sources as possible, although the risk is low and under debate.
    No preview · Article · Dec 2007