Y Manor

Tel Aviv University, Tell Afif, Tel Aviv, Israel

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Publications (52)88.89 Total impact

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    ABSTRACT: Purpose: To determine the level of bacterial contamination in immediate implantation or augmentation sites vs pristine bone, before and after saline rinses. Materials and methods: Bacterial samples were taken from fresh extraction sites (17 patients) and pristine bone (15 patients) before performing implant dentistry surgical procedures. Levels of bacterial contamination were estimated before and after saline rinses. Samples from the socket were placed on an agar plate for total bacterial account and on selective plates for Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis counts. Results: The level of bacterial contamination before saline rinse was 1.2 × 10(4) units of bacterial colony (CFU)/mL in fresh extraction sites (study group) and 5 × 10(2) CFU/mL in pristine bone sites (control group). After a saline rinse, the bacterial level was lowered significantly to 5.2 × 10(3) CFU/mL in the study group and to zero in the control group (P < .05). Levels of bacterial contamination were higher in the mandibular sockets (7.5 × 10(3) CFU/ml) than in the maxillary sockets (5.6 × 10(3) CFU/mL), and the difference was statistically significant (P = .034). All implanted/augmented fresh or pristine sites survived in the follow-up period. Conclusion: Fresh extraction sockets with clinical signs of infection show bacterial presence. Pristine bone shows a lower bacterial level. Saline rinse in addition to a decontamination protocol may reduce the level of bacterial contamination significantly both in fresh extraction sites and pristine bone.
    No preview · Article · Nov 2015 · The International journal of oral & maxillofacial implants

  • No preview · Article · Sep 2015 · The Journal of craniofacial surgery
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    ABSTRACT: Purpose: To evaluate the survival rate of dental implants replacing failed implants in grafted maxillary sinuses using the lateral approach vs nongrafted posterior maxillae. Materials and Methods: A retrospective analysis was conducted to study the survival of secondary dental implants inserted in the posterior maxilla in previously failed implant sites between the years 2000 and 2010. The study group consisted of patients who had also undergone maxillary sinus augmentation, and the control group consisted of patients in whom implants in the posterior maxilla had failed. Clinical and demographic data were analyzed using a structured form. Results: Seventy-five patients with a total of 75 replaced implants were included in the study. The study group comprised 40 patients and the control group, 35 patients. None of the replaced implants in the study group failed, resulting in an overall survival of 100%; three replaced implants in the control group failed (92% survival). The main reason for the primary implant removal was lack of osseointegration (35 [87.5%] of 40 study group implants and 23 [65.7%] of 35 control group implants [P = .027]). The difference between the groups with regard to the timing of primary implant failure was statistically significant. The study group had more early failures of the primary implant than did the control group (77% vs 62%; P = .038). Conclusion: Dental implants replaced in the posterior maxilla had a high survival rate. A higher rate of survival was found in augmented maxillary sinus sites. Within the limits of the present study, it can be concluded that previous implant failures in the grafted maxillary sinus should not discourage practitioners from a second attempt.
    No preview · Article · Sep 2015 · The International journal of oral & maxillofacial implants
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    Manor Y · Mardinger O · Zaks O · Haim D · Manor A · Chaushu G

    Full-text · Article · May 2015
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    ABSTRACT: Objective: To determine and investigate the effect of bacterial contamination on implant survival rate. Method: A prospective cohort study was conducted on patients planned for dental implantation who agreed to participate in the study. Levels of bacterial contamination was estimated before and after saline rinses in immediate implantation/augmentation (study) and late implantation (control) sites. Samples from the socket were plated onto appropreate agar plates for total bacterial counts and on selective agar plates for Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) counts. The clinical situation of the augmented / implanted area was followed up for 1-3 years. Results: Thirty two patients participated in the study and were devided to either experimental (N=17) or control group (N=15). Significant differences were found between the two groups before and after the saline rinse (P<0.005). Significant positive correlations were found between prevalence of the periopathogens Aa and Pg and bleeding on probing and presence of oral malodor. None of the cases has revealed evidence for late infection of the graft/implant. All augmentations and dental implantations have survived during the follow up period (3 years). Conclusions: A high level of bacterial contaminationwas found in clinically infected extraction sockets, with higher levels in the mandible. Meticulous debridment and saline rinse can lower the contamination level. Immediate implantation or augmentation in clinically and microbiologically infected sites can be treatment of choice, without engdangaring survival rates, as long as debridment and rinses are performed.
    No preview · Conference Paper · Jun 2013
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    ABSTRACT: Objectives : to evaluate the survival rate of dental implants replacing failed implants in grafted maxillary sinuses by lateral approach compared to replacing failed implants in non grafted posterior maxillae. Methods: retrospective analysis of 75 patients undergone re-implantation in posterior maxillae. The study group composed of 40 patients who had failed and replaced implant in grafted posterior maxilla by lateral approach sinus floor augmentation sites, and a control group composed of 35 patients who had failed and replaced implant in pristine sites of posterior maxilla. The collected date were analyzed for mean ± standard deviation (SD) using SPSS 10.0, SPSS Chicago IL, with a significant level of 5% using T-Test, Mann Whitney, Chi-Square test and survival with Kaplan-Meier. Results: In a follow up period of 5 years in average, there were no failure of the secondary implants, so 100% survival in the replacing implants (75 implant). The main reason for failure was lack of osseointegration, and it was more pronounced in the study group. (p=0.027) A higher rate of early failure was found in the study group. (p=0.038) Conclusions: According to the current research, the high survival rates of dental implants replacing failed implants in posterior maxilla with or without sinus floor augmentation- 100% survival for 5 year follow up- leads to the conclusion that the maturation level of bone graft may play a role in the early failure of the dental implant and leads to higher survival rate in the replacing implant. With the limitations of this research, we can conclude that dental implant failure after sinus floor augmentation should not prevent the practicioner from second attempt.
    No preview · Conference Paper · Jun 2013
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    ABSTRACT: Overall first-year failure rate for dental implants may reach 3%-8% as the result of various complications. Accordingly, reimplantation accounts for an ever-growing portion of clinic's practice. The purpose of the present study was to evaluate the survival rate of dental implants that were performed in sites where failed implants were previously removed and to evaluate the factors affecting outcome. Three certified oral and maxillofacial surgeons inserted 144 implant replacement in previously failed sites in 144 patients (1994-2009). Clinical and epidemiologic data were collected retrospectively and analyzed regarding survival rates. Survival rate of the implants replacing previously failed ones was 93% (133/144). A third placement in the same site was performed in 7 of 11 patients with a survival rate of 85% (6/7) up to the last follow-up. No correlations were found between replaced implant failures with any of the parameters examined. Within the limits of the present study, it can be concluded that a previous implant failure should not discourage practitioners from a second or even a third attempt.
    No preview · Article · Sep 2012
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    A. Rybalov · E. Kagan · Y. Manor · I. Ben-Gal
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    ABSTRACT: In this work we consider a navigation of quantum-controlled mobile robot by the use of fuzzy methods. A fuzzy model of the robot behavior is obtained by transformation of the robot's states (that appear in a form of qubits) into the pairs of membership functions. For a full description of the robot's turns, we define a reverse fuzzy Hadamard operator that completes the known Hannachi, Hatakeyama and Hirota model. The suggested transformations and methods were comparatively studied by field trials using small mobile robots and by numerical simulations that model the robot's behavior in the presence of noise.
    Full-text · Conference Paper · Dec 2010
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    ABSTRACT: The aim of this study was to assess the incidence of late signs and symptoms of acute and chronic maxillary sinusitis after sinus augmentation and to correlate them with predisposing factors. A total of 137 individuals (54 male and 83 female; 153 sinus augmentation procedures) were evaluated retrospectively for signs and symptoms of maxillary sinusitis, 12-80 months after surgery, using a questionnaire and clinical and radiographic examinations. The incidence of acute and chronic sinusitis after sinus augmentation was low (<5%). History of preoperative sinusitis (P = .001) and sinuses with thick mucosa (P < .0001) were statistically significant factors correlated with late signs and symptoms of sinusitis. There was a slight correlation between chronic sinusitis and women (P = .079) or 2-stage procedures (P = .098). There was no statistical correlation to intraoperative complications, such as membrane perforation and excessive bleeding. The occurrence of postoperative chronic sinusitis appears to be limited to patients with history of preoperative sinusitis and sinuses with thick mucosa, despite control of the disease before sinus augmentation. Intraoperative surgical complications have negligible effect. Patients presenting with preoperative sinusitis and sinuses with thick mucosa need to be informed of the increased risk. They require a close follow-up and prompt treatment in the event of signs and symptoms of sinusitis.
    No preview · Article · Jul 2010 · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
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    ABSTRACT: This study was a retrospective assessment of reentry sinus augmentation compared with sinus augmentation performed for the first time. There were 38 subjects who required sinus augmentation. The study group (17 patients, 21 sinuses) included subjects following failure of a previous sinus augmentation procedure that required reentry augmentation. The control group (21 patients, 21 sinuses) included subjects in which sinus augmentation was performed for the first time. Patients' medical files were reviewed. A preformed questionnaire was used to collect data regarding demographic parameters, medical and dental health history, habits, and intra- and postoperative data. Operative challenges in the study group included adhesions of the buccal flap to the Schneiderian membrane (62%, 13/21, P<.001), bony fenestration of the lateral wall with adhesions (71%, 15/21, P<.001), limited mobility of a clinical fibrotic Schneiderian membrane (71%, 15/21, P<.001), and increased incidence of membrane perforations (47%, 10/21, versus 9.5%, 2/21, P=.03). In the control group the Schneiderian membrane was thin and flexible. Sinus augmentation succeeded in all cases of both groups. Implant failure was significantly higher in the study group (11% versus 0%, P<.001). Clinical success of reentry sinus augmentation is predictable despite its complexity. Clinicians should be aware of anatomical changes caused by previous failure of this procedure. Patients should be informed about the lower success rate of implants when reentry sinus augmentation is required.
    No preview · Article · Apr 2010 · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
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    ABSTRACT: Implant failures can be divided into early and late according to the timing of failure. The purpose of this study was to characterize and compare both types. A retrospective cohort study was conducted in 194 patients (98 men and 96 women) who presented after dental implant failures during a 6-year period (2000 to 2006). The patient served as the unit of analysis. A history of at least 1 failed and removed dental implant served as the inclusion criterion. Patients were excluded from this study whenever their files had missing data. The collected data included a patient's characteristics, failure characteristics, and the anatomic status of the alveolar ridge after failure. Late failures were associated with moderate to severe bone loss, a larger number of failed implants per patient, a higher incidence in men, and mostly in posterior areas. Early failures were associated with minimal bone loss, occurred more in women, at a younger age, and in most cases the implants were intended to support single crowns. Meticulous follow-up is needed to reveal and treat failing or ailing implants. Once established as hopeless, they should be removed as soon as possible to prevent further bone loss.
    Full-text · Article · Dec 2009 · Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons
  • M Szyper-Kravitz · R Lang · Y Manor · M Lahav
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    ABSTRACT: 46-year-old patient with acute myeloid leukemia (AML) whose disease manifested as fever, chills and dry cough is reported here. Despite broad antibiotic coverage he remained acutely ill with spiking fever, shaking chills, and hypoxemia. His initial chest radiograph was normal but chest computed tomography (CT) scan disclosed bilateral focal infiltrates. Hypoxemia and severe thrombocytopenia precluded invasive diagnostic procedures. A thorough epidemiological investigation revealed that before becoming acutely ill the patient smoked daily tobacco mixed with marijuana from a "hookah bottle". While waiting for tobacco and "hookah water" cultures, we started antifungal therapy. Resolution of fever and hypoxemia ensued after 72 hours. Tobacco cultures yielded heavy growth of Aspergillus species. We suggest that habitual smoking of Aspergillus-infested tobacco and marijuana caused airway colonization with Aspergillus. Leukemia rendered the patient immunocompromised, and allowed Aspergillus to infest the lung parenchyma with early occurrence of invasive pulmonary aspergillosis. Physicians should be aware of this potentially lethal complication of "hookah" and marijuana smoking in immunocompromised hosts.
    No preview · Article · Jul 2009 · Leukemia and Lymphoma
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    ABSTRACT: The purpose of the present study was to explore the major factors that can affect the decision to replace failed implants. A retrospective cohort study was conducted on 194 patients who presented following dental implant failure during a 6-year period (2000 to 2006). The collected data included patient characteristics, failed implant characteristics, the anatomic status of the alveolar ridge after failure, and factors affecting the decision to avoid reimplantation. The study group included patients in whom the failed dental implants were replaced, whereas there was no reimplantation in the control group. Seventy-four patients (135 implants) made up the control group, and 120 patients (157 implants) made up the study group. The mean patient age was higher and the medical status was worse in the control group. The number of failed implants per patient was higher in the control group. The time between the diagnosis of failure and removal and between implant placement and removal were greater in the control group. The chances of a patient with minor bone loss undergoing reimplantation was 20 times greater (odds ratio, 20.4) than a patient with severe bone loss. The main patient-related reasons for avoiding reimplantation were the additional costs (27%), fear of additional pain (17.7%), and fear of a second failure (16.2%). The removal of a failing implant as soon as it is diagnosed as hopeless will improve the chances for reimplantation.
    No preview · Article · Jan 2009 · Journal of Periodontology

  • No preview · Article · Jul 2007
  • N Gronich · J Radnay · H Shapiro · Y Manor · M Lahav · M Lishner
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    ABSTRACT: Bone marrow (BM) involvement in low-grade non-Hodgkin's lymphoma (NHL) has a clear impact on patients' survival. The standard practice is morphological examination of BM biopsy at diagnosis. The clinical significance of flow cytometry (FC) analysis of BM aspirates is largely unknown. The medical charts of 70 low-grade NHL patients, who underwent BM biopsy and FC analysis between 1994 and 2004, were reviewed. Forty-three patients (61.4%) were BM+ by morphology, while in those without morphological involvement by lymphoma FC was positive in 9 (BM-FC+, 12.9%) and negative in 18 (BM-FC-, 25.7%). The median treatment-free period was shorter in the BM+ and BM-FC+ groups compared with the BM-FC- group (1 and 4 months vs. 31 months, respectively) (log-rank test, P = 0.0195). The median survival time was not reached for the BM-FC- patients, whereas for BM+ and BM-FC+ patients it was 129 and 89 months, respectively, with no significant difference between them [the difference between the BM-FC- and the two other groups was statistically significant (log-rank test, P = 0.029)]. The outcome of low grade NHL in patients who had BM involvement by FC alone or by morphology was similar. If confirmed, these findings suggest a modification in the workup and management of localized low grade NHL.
    No preview · Article · May 2007 · European Journal of Clinical Investigation
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    ABSTRACT: To describe the anatomy of the lingual perimandibular vessels and emphasize the distance to the bone. The hemifacial lower third was dissected in 12 human cadavers. The blood vessels in the floor of the mouth were exposed using sagittal incisions at the canine, mental foramen, and second molar areas. The diameter of the dissected vessels ranged from 0.5 to 3 mm (mean, 1.5 mm). Most vessels were found superior to the mylohyoid muscle in the canine area and beneath the muscle in the mental and second molar areas. The smallest median vertical distance from blood vessel to bone was in the canine area (14.5 mm), followed by the mental foramen area (15.5 mm) and the second premolar area (19 mm). The median horizontal distance of the vessels from the lingual plate was 2 mm at the canine and second molar areas and 4 mm at the mental area. Lingual plate perforation, especially anterior to the canine area, can easily injure blood vessels in the floor of the mouth and cause life-threatening hemorrhage following implant placement. Bleeding can occur when the mandibular lingual plate is perforated. Care should be taken to recognize situations where this complication may occur. Based on the study of human cadavers, it appears that vessels in the floor of the mouth are sometimes in close proximity to the site of implant placement. Caution should be exercised when placing implants in this area.
    Full-text · Article · Jan 2007 · The International journal of oral & maxillofacial implants
  • Yifat Manor · Danielle Blinder · Shlomo Taicher
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    ABSTRACT: Intraoral vertical ramus osteotomy (IVRO) and advancement genioplasty are effective and predictable methods of treating selective individuals with mandibular prognathism. The sequence of performing these procedures does have a clinical effect, but this is not found in the literature. The purpose of this article is to introduce the clinical implication of the sequence of procedures and to recommend the preferred sequence based on experience. A retrospective study was conducted on 75 patients treated by IVRO with or without genioplasty. In 31 patients, IVRO was performed without genioplasty; only one patient suffered from transient hypoesthesia. When IVRO was performed before genioplasty (sequence I) in 20 patients, nine suffered from mental nerve hypoesthesia. However, when IVRO was performed after genioplasty (sequence II) in 24 patients, permanent mental nerve anesthesia occurred in five patients and mental nerve hypoesthesia in 15 patients. Based on these results, it is recommended that IVRO be performed before genioplasty.
    No preview · Article · May 2006 · Cranio: the journal of craniomandibular practice
  • A Amiel · M Yukla · S Yogev · Y Manor · M D Fejgin · M Lishner
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    ABSTRACT: Multiple myeloma represents a malignant proliferation of plasma cells derived from a single clone. It is well known that alkylating agents are capable of inducing myelodysplastic syndromes (MDS) and acute myelocytic leukemias (AML). This risk of both diseases in patients with multiple myeloma has been estimated to be 10-20% after 10 years. We aimed to evaluate the time course and the type of genetic abnormalities in melphalan-treated patients in the chronic stage of the disease. We applied fluorescence in situ hybridization methods with probes to 5q31 and 7q31 to mononuclear peripheral blood leukocytes of 18 melphalan-treated patients and compared the results to those of 8 untreated myeloma patients. We found three patients (17%) with a 5q31 deletion in their peripheral white blood cells, but no 7q31 deletion. These findings suggest that 5q- occurs before the overt development of MDS/AML and raise important concerns regarding long-term treatment of myeloma patients with alkylating agents. Also, the performance of cytogenetic evaluation should be considered before autologous transplantation. The clinical and biological implications of these findings should be evaluated in larger clinical and laboratory studies.
    No preview · Article · Aug 2004 · Cancer Genetics and Cytogenetics
  • Y Manor · O Mardinger · J Katz · S Taicher · A Hirshberg
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    ABSTRACT: Peripheral odontogenic tumours (POT) are rare benign focal overgrowths of the oral soft tissue, usually occurring in the gingiva. Between 1996-2000, 6 out of 406 excised gingival lesions were diagnosed as POT (1.5%). Tumours included peripheral odontogenic fibroma (2 patients), peripheral calcifying odontogenic cyst (2 patients), peripheral ameloblastoma (1 patient), and peripheral calcifying epithelial odontogenic tumour (1 patient). Review of the literature reveals that peripheral odontogenic fibroma and peripheral ameloblastoma were the most common POT. The purpose of this article was to analyse the clinical data of these tumours according to the presented cases and the literature review, to elucidate typical features of each tumour type and enhance easy identification.
    No preview · Article · May 2004 · International Journal of Oral and Maxillofacial Surgery
  • D Blinder · Y Manor · U Martinowitz · S Taicher
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    ABSTRACT: The purpose of this study was to evaluate the incidence of postoperative bleeding in patients treated with oral anticoagulant medication who underwent dental extractions without interruption of the treatment and to analyze the incidence of postoperative bleeding according to the International Normalized Ratio (INR) value. The 249 patients who underwent 543 dental extractions were divided into five groups: Group 1 with INRs of 1.5-1.99, Group 2 with INRs of 2-2.49, Group 3 with INRs of 2.5-2.99, Group 4 with INRs of 3-3.49 and Group 5 with INRs>3.5. The INR was measured on the day of the procedure. Local haemostasis was carried out with gelatin sponge and multiple silk sutures. Of the 249 patients, 30 presented with postoperative bleeding (12%): Group 1, three patients presented with bleeding (5%), Group 2, 10 patients (12.8%), Group 3, nine patients (15.2%), Group 4, five patients (16.6%) and Group 5, three patients (13%). The incidence of postoperative bleeding was not significantly different among the five groups. The value of the INR at the therapeutic dose did not significantly influence the incidence of postoperative bleeding. Thus, dental extractions can be performed without modification of oral anticoagulant treatment. Local haemostasis with gelatin sponge and sutures appears to be sufficient to prevent postoperative bleeding.
    No preview · Article · Dec 2001 · International Journal of Oral and Maxillofacial Surgery

Publication Stats

810 Citations
88.89 Total Impact Points


  • 1995-2015
    • Tel Aviv University
      • • Department of Oral and Maxillofacial Surgery
      • • Sackler Faculty of Medicine
      • • Faculty of Medicine
      Tell Afif, Tel Aviv, Israel
  • 1993-2009
    • Meir Medical Center
      • Department of Obstetrics and Gynecology
      Kafr Saba, Central District, Israel
  • 1999
    • Sheba Medical Center
      • Department of Pathology
      Gan, Tel Aviv, Israel