[Show abstract][Hide abstract] ABSTRACT: Lipoma is a common soft-tissue tumour of mature fat cells. Although surgical excision is effective, treatments that are less invasive and not associated with disfigurement of scar would be ideal for the treatment of lipomas. Recently, tumescent liposuction has been used for the treatment of lipomas.
To evaluate the efficacy of tumescent liposuction in lipoma treatment, we reviewed our experience of lipoma treatment by tumescent liposuction.
A total of 21 patients presenting with 31 lipomas were treated with tumescent liposuction. After liposuction, remaining stromas were removed by a haemostat through the small incision. Tumour size and post-operative complications were recorded before and after treatment.
A total of 31 lipomas of 21 patients were treated by tumescent liposuction. The size of lipomas ranged between 1.2 and 11 cm (mean size, 4.1 cm). In 23 cases, there were no complications. However, remnant lipomas, bruise, haematoma and immediate dimpling were found as complications.
Tumescent liposuctions with extracting remnant fat tissue and fibrous tissue through the opening for liposuction can be an effective treatment technique in lipoma treatment in the efficacy and cosmetic outcomes and this method can be a substitute for excision in treating large lipomas.
No preview · Article · Mar 2007 · Journal of the European Academy of Dermatology and Venereology
[Show abstract][Hide abstract] ABSTRACT: Basal cell carcinoma gap (BCC) is the most common malignant tumor of the skin and often occurs on the face. Many types of local flaps are used to reconstruct the skin defect after excision. We report a case of basal cell carcinoma located on the nose tip, treated with an island flap.
No preview · Article · Sep 2006 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Background: Surgery of the nasolabial area is susceptible to the distortion of lips, commissure and nasal ala. A subcutaneous pedicle flap is suitable for surgical treatment of mid-size facial defects. Objective: To evaluate the effectiveness of a subcutaneous pedicle flap for surgical defects of the nasolabial area. Method: We reviewed the medical records and evaluated clinical aspects and surgical treatment outcomes. Results: Total number of patients was 13, including 8 males and 5 females. Mean age was 67.7 years-old. Surgical defects were present on the alar crease in 9 cases, and upper lip in 4 cases. Mean size of defects was 1.6 by 1.3 cm. Flaps were well adopted, and no surgical scars were visible. No distortion of the adjacent structures were left. However, the alar crease was slightly blunted in one patient. Conclusion: A subcutaneous pedicle flap is suitable for reconstruction of nasolabial area defects.
No preview · Article · Jul 2005 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Pilar sheath acanthoma is one of the benign follicular hamartoma, with a level of differentiation between trichofolliculoma and dilated pore of Winer. It differentiates toward infundibulum, isthmus, and rarely, sebaceous duct, apocrine, inner root sheath, and hair bulb components. It is a dome-shaped, symmetrical, sharply-circumscribed neoplasm that measures about 1cm in diameter. We herein report a case of pilar sheath acanthoma on the forehead of a 62-year-old male patient.
No preview · Article · Jun 2005 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Reconstruction of partial car defects presents a unique and notable challenge to the dermatologist. This is due to the complex architecture of the external ear which is difficult lo duplicate surgically. Several procedures are available for correction of defects to the external ear. However, the diversity of external ear shapes shows how difficult it is to achieve a certain solution to this problem. We report a case of auricular squamous cell carcinoma in which the skin defect is reconstructed by a staged supra-auricular interpolation pedicle flap.
No preview · Article · Apr 2005 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Desmoplastic trichoepithelioma is a rare benign tumor which is most commonly found on the face of young females. The tumor has a raised, annular border and a depressed center. The histologic features are often confused with other skin diseases, especially with mierocystic adnexal carcinoma. We report, herein, a case of desmoplastic trichoepithelioma in a 26-year-old man, confirmed by re-biopsy and CEA immunohistochemical study.
[Show abstract][Hide abstract] ABSTRACT: Background: The lips have an asethetic and functional importance. There are various types of lip defects, and these are mainly due to tumor excision. Although there are numerous techniques available to repair the lips, no universal reconstruction method is presently available, and reconstruction of lip defects are inherently difficult. Objective: To report surgical reconstruction results of lip defects. Method: Our study involved eleven patients, who had visited our dermatologic surgery clinic between 1995 and 2003, and had been histopathologically diagnosed as having either a basal cell carcinoma or squamous cell carcinoma on the lips. The medical records were reviewed, and clinical features, surgical methods, and cosmetic and functional results were evaluated. Results: Wedge resection, resection with W-plasty, the subcutaneous pedicle flap, and dual mucosal flap technique were used to repair lip defects surgically. The vermilion border was aligned well in all the patients, and a post-operative scar was not apparent. However, a microstomia developed in one patient. Conclusion: The dermatologic surgeon should be familiar with various reconstruction options for lip defects. An appropriate choice depends on the size, location and depth of the defect. Specific functional and aesthetic aspects of the lips should be taken into account when planning and performing an operation.
No preview · Article · Feb 2005 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Background: Squamous cell carcinoma of the finger and toe is a relatively rare disorder which has often been misdiagnosed for years before definite diagnosis. Squamous cell carcinoma of the finger has usually been found to be associated with type 16 human papillomavirus (HPV). Objectives: To describe the clinical and histological features of 12 squamous cell carcinomas of the finger and toe, and to evaluate these lesions for the presence of HPV. Method: The clinical and histological features were reviewed. Immunohistochemical staining and PCR were performed in paraffin embedded tissue sections for detection of the presence of HPV infection. Results: Patients presented with an erosive or a verrucous papule. Histologically, 2 lesions demonstrated bowenoid features, 9 lesions demonstrated well differentiated squamous cell carcinoma, and 1 lesion demonstrated verrucous carciroma-like features. By immunohistochenical staining and PCR, we could not demonstrate any evidence of HPV infection in any of the cases. The affected digit was amputated in 10 cases, and complete excision of the skin lesion was done in 2 cases. Conclusion: Squamous cell carcinoma of the finger and toe is not as rare as has been implied by early literature. It is important to carry out the skin biopsy from all recalcitrant lesions of the finger and toe.
No preview · Article · Jan 2005 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Background: Forty percent of solar irradiation arriving on the ground surface is infrared rays (IR). However, these have received little attention. Chronic experimental exposure to IR has been found to cause degenerative changes to dermal connective tissue and an accumulation of ground substances, which is similar to changes which occur by photoaging. Objective: To investigate the effects of persistent heat exposure on the cutaneous aging symptoms such as wrinkles, dyspigmentation and telangiectasia. Methods: A total of 306 male volunteers, aged between 26-68 years, were recruited from steel factories with a torrid working environment. Each volunteer was interviewed for demographic information, cumulative sunlight exposure levels and their smoking history. Skin examination and measurement of erythema/pigmentation levels were also performed on the crow's feet area of the face and/or the upper inner arm. Results: 1. The group of males, aged 50years or over, who had been exposed to high temperatures for more than 10years showed a tendency to have severer wrinkles (5.1±1.5) than an age-matched control group (3.7±0.1). 2. There was no correlation between dyspigmentation and heat exposure. 3. Erythema indices decreased and were found to be dependent on the duration of heat exposure to the face in the group of males over 40years of age, and to the upper inner arm in the group of males over 50years of age. Conclusion: Chronic heat exposure might contribute to the development of skin wrinkles and shows the possibility of potentiation of extreme ultraviolet effects.
No preview · Article · Aug 2004 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Background: There have been several reports of patients with a severe hydroa vacciniforme (HV)-like eruption from Asia and Latin America. The cutaneous lesions are present in both sun-exposed and nonexposed areas in these patients unlike true HV. Several patients have died of malignant hematologic malignancies. The latent Epstein-Barr virus (EBV) infection has been detected in the skin lesions of the patients. Objective: To describe clinical, histological, immunohistochemical, and molecular pathological features of the patients with EBV associated lymphoproliferative lesion presenting as a HV-like eruption. Methods: The clinical, histological, and immunohistochemical features of 16 patients were reviewed. The presence of T-cell receptor (TCR)-γ gene rearrangement was investigated using polymerase chain reaction (PCR) technique. Photoprovocation by repetitive UVA exposure was performed in five patients. In situ hybridization was performed to detect mRNA for EBV in the lesional skin biopsy specimen, lymph node biopsy specimen, mucosal biopsy specimen of stomach, and the skin biopsy specimen of photo-provoked site. PCR was performed to detect DNA for EBV in the skin biopsy specimens of 6 patients and peripheral mononuclear cells of 2 patients. Results: The severity of the skin lesion and the clinical course varied among the patients. Skin biopsy specimens obtained from a papule or a vesicle showed perivascular and periadnexal infiltrate of lymphoid cells with T-cell phenotype. However, clonal TCR-γ gene rearrangement was not detected in all 8 patients. Papules or vesicles were induced by repetitive UVA exposure in 5 patients. A latent EBV infection was demonstrated in all the tested samples, such as lesional skin, lymph node, gastric mucosa, peripheral blood mononuclear cells, and the photo-provoked lesion. Conclusion: EBV associated lymphoproliferative lesion presenting as a HV-like eruption is a novel disease that is not related to classic HV. Repetitive irradiation of UVA can induce the skin lesion in some patients with EBV associated lymphoproliferative lesion presenting as a HV-like eruption.
No preview · Article · Jul 2004 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Background: Actinic keratosis is a proliferation of transformed neoplastic keratinocytes that are confined to the epidermis, and is induced by exposure to UV radiation in sunlight. The neoplastic transformation is primarily due to p53 gene mutation. Objective: Our purpose was to study the correlation among p53 expression, epidermal hyperplasia, dermal inflammation, Ki-67 expression, and p21 expression in the actinic keratosis. Methods: We reviewed the histopathologic slides of 21 cases of actinic keratosis. We performed immunoperoxidase staining using monoclonal antibody to p53 protein, Ki-67 antigen, p21 protein on the specimen. We stastically analyzed the correlation among p53 expression, epidermal hyperplasia, and dermal inflammation, Ki-67 expression, and p21 expression. Result: We found higher expression of p53 in the actinic keratosis with hyperplastic epidermis but this finding was not stastically siginificant (p=0.233). There was no correlation between the expression level of p53 and the severity of dermal inflammation (p=0.755). The expression level of p53 had the significant positive correlation with the expression level of Ki-67 (p=0.001). There was no correlation between the expression level of p53 and the expression level of p21 (p=0.116). Conclusion: We observed that p53 expression had a significant positive correlation to only Ki-67 expression. We suggested that further study would be needed on the correlation among p53 expression, epidermal hyperplasia, dermal inflammation, and p21 expression in actinic keratosis.
No preview · Article · May 2004 · Korean Journal of Dermatology
[Show abstract][Hide abstract] ABSTRACT: Cutaneous protothecosis sometimes poses diagnostic and therapeutic problems. Isolation of the causative organism may not be successful and spores may be mistaken for other diseases unless the characteristic sporangia are detected in tissue sections. Because there are few cases, the optimal therapy is still being debated. Our purposes were to detect any characteristic findings of Prototheca wickerhamii under light microscopy in order to aid diagnosis and to determine which drugs were effective. On crystal violet staining we found characteristic bluish dots in Prototheca spores; these correspond to the amyloplasts or dense bodies found under electron microscopy. In vitro the isolated organisms were inhibited by itraconazole, amphotericin B, ketoconazole, and amorolfine and we were able to successfully treat three patients with itraconazole. Crystal violet staining can be helpful in diagnosing protothecosis, especially when the causative organism has not been isolated. The therapeutic effect of itraconazole was confirmed in vivo and in vitro.
No preview · Article · Jan 1997 · Nippon Ishinkin Gakkai Zasshi