[Show abstract][Hide abstract] ABSTRACT: The histological and immunohistochemical features of four tumors displaying the characteristic pattern of Giant Cell Fibroblastoma (GCF) are presented. Three of them were found in association with classical and/or myxoid dermatofibrosarcoma protuberans, while the fourth tumor was a retroperitoneal malignant hemangiopericytoma where foci with features of GCF were found. Typical sinusoidal spaces and the bizarre mononuclear and multinucleated cells in close association to blood vessels presenting a wide spectrum of lesions of their walls are also described. These last changes led us to believe that GCF-like lesions might not always characterize an entity but could often represent a host reaction of the connective tissue to locally aggressive or malignant tumors.
No preview · Article · Feb 1999 · Pathology - Research and Practice
[Show abstract][Hide abstract] ABSTRACT: Intraosseous lipomas are considered to be among the rarest primary benign bone tumors. Lipoma developing in bone frequently presents evolutional changes, which in association with the lack of clinical information and the radiographic appearance of the bone lesion could be the main reasons for misinterpretation of the histological picture. We present three cases of intraosseous lipoma which developed in male patients aged 23, 34 and 35 years, involving the tibia (n = 2) and calcaneus (n = 1). The histologic pattern of all tumors was that of mature adipose tissue. The diagnosis was made by correlating the clinical and radiographic findings to those of light microscopy.
Preview · Article · Feb 1994 · Archives d'anatomie et de cytologie pathologiques