Anne Lichtenberg

Copenhagen University Hospital, København, Capital Region, Denmark

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Publications (5)11.63 Total impact

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    ABSTRACT: Mental health surveillance in infancy was studied in an existing child health surveillance programme with child psychiatric disorder at 1(1/2) year as the outcome. Children considered of concern by community health nurses were cases in a case control study nested in the Copenhagen Child Cohort (CCC 2000). Outcome was mental health status at 1(1/2) year assessed by clinical and standardised strategies, including videotape recordings, parent interviews and the instruments: CBCL 1(1/2)-5, ITSCL, CHAT, Bayley Scales of Infant Development II, PC ERA and PIR-GAS. The positive predictive value of concern in the first 10 months of living was 24% (CI 17.0-31.9), the negative predictive value was 85% (CI 77.9-89.6) and the sensitivity was 56% (CI 42.4-69.0). Concern about development was significantly associated with the child having a neuro-developmental disorder at 1(1/2) year, and concern about mother-child relationship was associated with emotional, behavioural, eating, and sleeping disturbances. A general health surveillance program seems to have potentials to identify infants at risk for mental health problems provided standardised measures and specific training of the involved health professionals.
    No preview · Article · Mar 2008 · European Child & Adolescent Psychiatry
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    ABSTRACT: The prevention of disorders in social communication and attention is hampered by the lack of effective tools to screen in the first year of living. In Denmark public health nurses perform screening of physical and mental health in all infants, and at the age of 8-10 months a standardised test, BOEL, is performed to screen for hearing loss plus social communication and attention disturbances. The predictive value of abnormal reactions at the BOEL test at 8-10 months of age was investigated in a subpopulation of 211 children from the CCCC 2000. Predictions were calculated in relation to outcome concerning psychopathological disturbances in social communication and attention, diagnosed by child psychiatric assessment at 18 months. Communication and attention disturbances at 18 months were predicted by the BOEL test with predictive validity of positive test (PV pos) 29%, and the predictive validity of negative test (PV neg) 95%. The BOEL test was found superior to the general clinical judgement by the public health nurses. The infant mental health screening by public health nurses seems to have potential concerning early identification of social communication and attention disturbances by using the BOEL test, but investigations of larger populations and with a longer time of observation are needed.
    No preview · Article · Apr 2007 · Ugeskrift for laeger
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    ABSTRACT: Epidemiological studies of psychopathology in the first years of life are few, and the associations between mental health problems in infancy and toddler age and mental health disturbances later in life have not been systematically investigated. This study aimed to investigate whether markers of mental health problems can be identified in the first years of life and thus increase the scientific foundation for prevention early in childhood. The population studied was a birth cohort of children born in Copenhagen County in year 2000, the Copenhagen County Child Cohort 2000 (CCCC 2000), which has been followed prospectively from birth. Mental and physical health are described at baseline based on Danish national registers and standardised records from home visits made by public health nurses. CCCC 2000 covers 6,090 children, of whom 5,624 (92%) have been described in health reports by public health nurses. In 13% of the cohort children, the general development was recorded as not normal, and in 12% language development was deviant. Problems with eating and sleeping were found frequently, in 30% and 20% of the children, respectively, and in 10% of the cases disturbances in the mother-child relationship were recorded. The first results from CCCC 2000 show that risk factors and markers of mental disturbances can be identified in at least 10% of children in the general population. The validity of these results is currently being investigated in follow-up studies of CCCC 2000.
    No preview · Article · Apr 2007 · Ugeskrift for laeger
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    ABSTRACT: The Copenhagen Child Cohort, CCC 2000, was established to investigate developmental psychopathology prospectively from birth in a general population. A random sample of 211 children from the CCC 2000 was investigated when the children were 1(1/2) years of age. The prevalence and associates of mental health problems and psychopathology were studied by clinical and standardised strategies, including videotape recordings, parent interviews and the following instruments: The Child Behavior Check List 1(1/2)-5 (CBCL 1(1/2)-5), The Infant Toddler Symptom Check List (ITSCL), Checklist for Autism in Toddlers (CHAT), Bayley Scales of Infant Development II (BSID II), The Parent Child Early Relationship Assessment (PC ERA) and Parent Infant Relationship Global Assessment Scale (PIR-GAS). Mental health problems according to International Classification of Diseases (ICD-10) and Diagnostic Classification Zero to Three (DC 0-3) diagnoses were found in 16-18% of 1(1/2)-year-old children. Most common were disturbances of emotion, behaviour and eating and the DC 0-3 diagnosis of regulatory disorder. Parent-child relationship disturbances were found in 8%. High psychosocial risk was significantly associated with emotional and behavioural disorders (OR 3.1 95% (1.2-8.1)) and disturbed parent-child relationship (OR 5.0 95% (1.6-16.0)). The strongest association of risk was found between relationship disorders and emotional and behavioural disorders (OR 11.6 95% (3.8-37.5)). The prevalence and distribution of psychopathology in 1(1/2)-year-old children seem to correspond to the distributions among older children. Disturbances in parent-child relationship have a key position in the risk mechanisms in early child psychopathology.
    Full-text · Article · Feb 2007 · Journal of Child Psychology and Psychiatry
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    ABSTRACT: Epidemiological studies of psychopathology in the first years of life are few, and the association between mental health problems in infancy and psychiatric disturbances later in life has not been systematically investigated. The aim of the present project was to study mental health problems and possibilities of intervention from infancy and onward. The basic study population consists of a birth cohort of 6,090 children born in the year 2000 in the County of Copenhagen, the Copenhagen County Child Cohort, CCCC 2000. At stage one CCCC 2000 was established on data from the Civil Registration System, Danish national registers, and standardized, longitudinal data from the first year of living obtained by public health nurses. At stage two a subsample was assessed at 1(1/2) years of age concerning child psychiatric illness and associated factors in a case-control study nested in the cohort, including a random sample. Participation rate at stage one was 92%. Ongoing studies of CCCC 2000 include studies of failure to thrive, register studies, and studies of the predictive validity of public health screening. A follow-up study concerning the prevalence of psychopathology at age 5 is planned. The Copenhagen County Child Cohort CCCC 2000 is a longitudinal study of mental health from infancy investigating psychopathology in early childhood. Results from this study will add to the knowledge of risk factors and course of mental health problems in childhood and contribute to the validation of the mental health screening made by public health nurses.
    No preview · Article · Feb 2005 · Scandinavian Journal of Public Health