S Janković

University of Belgrade, Beograd, Central Serbia, Serbia

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Publications (48)92.74 Total impact

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    ABSTRACT: Background: Previous studies suggest that alopecia areata (AA) may significantly affect patient quality of life (QoL). There are no studies that assess QoL in Serbian AA patients. Objectives: This study aims to assess the impact of AA on patients' QoL in comparison to patients affected by other skin diseases and to determine the impact of sociodemographic and clinical characteristics of AA patients on QoL. Methods: A hospital-based cross-sectional study of 60 patients with AA was conducted at the Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade between April 2012 and June 2013. The severity of hair loss was assessed using the Severity of Alopecia Tool (SALT). Patients' self-assessment of QoL was measured by three self-administered questionnaires: The Short Form-36 Health Survey (SF-36), Dermatology Life Quality Index (DLQI) and The Skindex-29. Results: Sixty AA patients (16 males and 44 females) with mean age of 37.35 ± 14.26 years completed the questionnaires. We confirmed that QoL of our AA patients was impaired. Compared with patients suffering from psoriasis, atopic dermatitis and onychomycosis AA patients presented significantly better QoL. Severity of disease (SALT) correlated only with personal relationship - dimension of DLQI (ρ = 0.29, P < 0.05) and social functioning - dimension of Skindex (ρ = 0.26, P < 0.05). No correlation was observed between severity of the disease and SF-36 subscales. AA patients with depression had significantly worse QoL in daily activities, leisure, work or school and personal relationships - DLQI dimensions, and emotions and social functioning - Skindex subscales. Conclusion: Our study demonstrates that AA influences QoL, but to a lesser degree than observed for psoriasis, atopic dermatitis and onychomycosis.
    No preview · Article · Dec 2015 · Journal of the European Academy of Dermatology and Venereology
  • M.R. Djurović · J. Janković · V.T. Spirić · S. Janković
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    ABSTRACT: Atopic dermatitis (AD) is a common, chronic skin disease in children that may affect their quality of life (QoL). The aim of this study was to assess QoL in children in Montenegro with moderate to severe AD. A cross-sectional study was conducted at the Clinic of Dermatology and Venereology, Clinical Center of Montenegro, Podgorica, between January and December 2014. The study group included 200 children (97 boys and 103 girls) with the diagnosis of AD. The Infants’ Dermatitis Quality of Life Index (IDQOL) and the Children’s Dermatology Life Quality Index (CDLQI) were used to determine QoL for 90 infants (<4 years old) and 110 children (4-16 years old), respectively. Severity of disease was measured by the three-item severity (TIS) score. The mean scores were 14.38±5.57 for IDQOL and 18.43±4.88 for CDLQI. A positive correlation was observed between AD clinical severity (TIS) and all the items of IDQOL with Spearman’s correlation coefficient (ρ) ranging from 0.31 to 0.74, and between AD clinical severity and all domains of CDLQI (ρ=0.31-0.69). The impact of AD on health-related quality of life (HRQoL) was more severe for younger girls, but only in some domains (IDQOL), and for older boys (CDLQI). The linguistically validated Serbian versions of both IDQOL and CDLQI questionnaires showed good internal consistency with Cronbach’s alpha values of 0.88 and 0.73, respectively. In conclusion, our results demonstrate that AD has a great impact on QoL. A positive correlation between clinical severity and quality of life was seen. © 2015, Croatian Dermatovenerological Society. All rights reserved.
    No preview · Article · Jan 2015
  • Burazeri G · Jankovic S · Laaser U · Martin-Moreno JM
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    ABSTRACT: See at www.seejph.eu
    No preview · Article · Oct 2013
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    ABSTRACT: Air pollution is one of the world's most serious environmental problems. Air pollutants continue to be major contributing factors to chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma), cardiovascular diseases, and cancer. We conducted a systematic literature review to provide some insight into what we currently know about the health problems associated with various air pollutants (especially ozone and particulate matter) and their relationship in promoting chronic respiratory diseases. Additionally, an overview of methodology used for evaluating the impact of air pollution on chronic respiratory diseases was done. A literature search targeted studies on the association between the effects of air pollution and respiratory health endpoints published between January 2000 and June 2010.
    No preview · Article · Jan 2012 · Polish Journal of Environmental Studies
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    ABSTRACT: Objective: Allergic rhinitis is a major respiratory disorder and represents a global health concern. Its prevalence is increasing over the last decades and the reasons for this increase are not completely clear. The aim of this study was to investigate the factors associated with allergic rhinitis in the adult Serbian population. Method: A case-control study of 100 outpatients with allergic rhinitis and 100 control subjects was conducted in Belgrade, Serbia in 2006. Cases and controls were matched by sex and age (± 5 years). A detailed questionnaire based on the latest research results in this field was used to obtain information about known risk factors. Univariate and multivariate logistic regression analyses were used for statistical analysis. Results: The following factors were dependently associated with occurrence of allergic rhinitis: allergic asthma (Odds Ratio [OR], 3.00; 95% confidence interval [CI], 1.36-6.64) and atopic dermatitis (OR, 4.24; 95%CI, 1.35-13.31) among family members, allergic rhinitis (OR, 24.07; 95%CI, 3.15-183.89), allergic asthma (OR, 6.22; 95%CI, 1.34-28.87), infections of the airways (OR, 3.49; 95%CI, 1.82-6.72) and drug allergy (OR, 2.95; 95%CI, 1.01-8.61) in childhood, atopic dermatitis (OR, 3.02; 95%CI, 1.03-8.83), sinusitis (OR = 3.34; 95%CI, 1.52-7.35), and breastfeeding in the first months (OR, 2.86; 95%CI, 1.17-6.96). Asthma among family members was the only independent risk factor for allergic rhinitis (OR, Conclusion: Our study indicates potentially important role of both genetic and environmental factors in the etiology of allergic rhinitis.
    No preview · Article · Jan 2010 · Healthmed
  • Jankovic S · Laaser U · Bjegovic V · et al

    No preview · Chapter · Jan 2010
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    ABSTRACT: The morbidity and mortality of cancers have a major impact on the population of Serbia. During 5-year period (1999–2003), the average standardized incidence rates for all cancers (all sites but non-melanoma skin cancer) were 241.9/100,000 for men, and 215.4/100,000 for women. In men, the most frequent was lung cancer, followed by colorectal, prostate, bladder and stomach cancers. In women, the incidence was highest for breast cancer, followed by cervical, colorectal, lung and corpus uteri cancers. The average standardized mortality rates for the same period were 159.5/100,000 for men, and 106.4/100,000 for women. In men the highest mortality rates were for lung cancer, followed by colorectal, stomach and prostate cancers. In women, breast cancer was on the first place as a cause of death followed by lung cancer, colorectal, cervical and stomach cancers. Stomach, colorectal, lung, breast and cervical cancers were responsible for 73,197 (19.9/1,000 population) disability adjusted life years – DALYs in men and for 60,482 (15.6/1,000) DALYs in women, on a yearly basis. The participation of years of life lost from premature mortality (YLL) in DALY was 95.2% in men and 93.2% in women. The greatest part of the DALY was caused by lung cancer in men and by breast cancer in women. During the period 1985–2002 in Serbia, there was a significant rise in the mortality from overall cancers, and among the most frequent cancers, for lung, breast and cervical cancers. The increase in lung cancer mortality rates was more pronounced in women. Increasing cancer mortality trends stress the importance of implementing preventive measures that have proved effective in other countries, especially screening for cervical cancer, the incidence of which in Serbia (25.8/100,000) was the highest in Europe.
    No preview · Chapter · Jan 2010
  • V. Tomic Spiric · S. Jankovic · M. Bogic · N. Maksimovic

    No preview · Article · Feb 2007 · Allergologie
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    ABSTRACT: Background: In the last decade of the 20th century, a considerable effort has been put into the development of summary measures of population health that combine information on mortality and non-fatal health outcomes. We used the DALYs (Disability adjusted life years) method to assess the burden of disease and injury in the population of Serbia. Methods: Our study, largely based on the methods developed for the Global burden of disease study, was conducted between October 2002 and September 2003. DALYs, stratified by gender and age, were calculated for 18 selected health conditions for the population of Serbia, Serbia and Montenegro for 2000. Years of life lost (YLL) were calculated using country mortality statistics, while years lived with disability (YLD) were calculated using different sources of information. Also, the YLD/YYL ratio and age-adjusted rates of DALYs were calculated. Results: Ischaemic heart disease, cerebrovascular diseases, lung cancer, unipolar depressive disorders, and diabetes mellitus were responsible for almost two-thirds (70%) of the total burden of 18 selected disorders in Serbia 2000. The leading five causes for males were ischaemic heart disease (26.DALY per 1000), stroke (17.9), lung cancer (12.7), road traffic accidents (6.5), and self-inflicted injuries (5.5). For females, the leading five causes were stroke (18.DALY per 1000), ischaemic heart disease (14.1), depression (8.7), breast cancer (6.1), and diabetes mellitus (5.2). Conclusions: The final results of the study have shown that the national health priority areas should cover cardiovascular diseases, cancers, and mental health.
    Full-text · Article · Feb 2007 · The European Journal of Public Health
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    ABSTRACT: Aim: To investigate the factors associated with atopic asthma in the adult Serbian population. Method: A case-control study of 134 atopic asthmatics and 134 non-asthmatics was carried out, during the period from March 2002 June 2003. The cases and controls were matched by sex, age (± 5 years) and place of residence (urban, rural). A detailed questionnaire based on the latest research results in the field was used to obtain information on the known risk factors. Stressful life events were recorded using Paykels Interview for Recent Life Events. Results: According to multivariate conditional logistic regression, the following factors were independently significantly associated with the occurrence of atopic asthma: allergic rhinitis (OR = 30.74, 95% CI = 7.62 - 123.98, p < 0.001), sinusitis (OR= 5.06, 95% CI = 1.27 - 20.17, p = 0.022), and lower respiratory tract infections in childhood (OR = 5.72, 95% CI = 1.65 - 19.87, p = 0.006). Conclusion: Our study indicates potentially important roles of allergic rhinitis, sinusitis and infections of the lower airways in childhood as factors increasing the risk of atopic asthma. Recognizing of the risk factors is important for the diagnosis and prevention of the disease.
    No preview · Article · Feb 2007 · Allergologie
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    ABSTRACT: Introduction: Allergic rhinitis is a chronic respiratory inflammatory disease affecting many aspects of patients daily activities. The aim of the present study was the comparison of quality of life between intermittent and persistent allergic rhinitis patients in pollen season and to test measurement properties of the Serbian version of Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Patients and methods: The investigation comprised 75 outpatients with intermittent and 25 outpatients with persistent allergic rhinitis, recorded from March to November 2002 at the Institute of Allergology and Immunology, Clinical Center Serbia, Belgrade. Medical Outcome Study Short Form Health Survey (SF-36) and RQLQ were used in the study. Results: Postnasal drip (t = 1.977, p = 0.051), itchy eyes (t = 2.756, p = 0.007), sore eye (t = 2.925, p = 0.004) and swollen eyes (t = 2.168, p = 0.033) were significantly more discomfortable to patients with intermittent than with persistent rhinitis, while mopping the floor was more troublesome to patients with persistent rhinitis (t = 3.166, p = 0.002) According to final multivariate logistic regression model, physical functioning (RR = 1.030, p = 0.020, 95% CI = 1.00 - 1.06) and sore eyes (RR = 1.546, p = 0.003, 95% CI = 1.16 - 2.07) were variables by which the patients with persistent and intermittent rhinitis differed significantly. Conclusion: Intermittent rhinitis patients in comparison with persistent rhinitis patients experienced significantly worse quality of life during pollen season. Serbian version of RQLQ has good discriminative properties and high reliability, and the specificity of our RQLQ version has been confirmed.
    No preview · Article · Dec 2006 · Allergologie

  • No preview · Article · Dec 2006 · Allergologie
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    ABSTRACT: The science and practice of the New Public Health have a key role in the promotion of people’s health and in the reform of the health system. Serbia experienced many social and economic threats to public health during the 1990s when the health infrastructure both for curative and preventive services gradually deteriorated. Existing skills and knowledge of public health professionals are insufficient in virtually all fields of public health activities. The foundation of the Centre – School of Public Health, within the Medical School of Belgrade University has been a precondition for the improvement of professional training in public health. The objectives are described as (1) education of capable experts in the field of public health, (2) improvement of knowledge in the health sciences, (3) health promotion in cooperation with local communities, (4) training of competent researchers in the field of public health and (5) improvement of the process of decision making and policy formulation. The training programme covers five key areas of education in the domain of public health: (1) public health in Europe, (2) epidemiology and biostatistics, (3) health policy and management, (4) health promotion, health education and social sciences and (5) environment and health. In the first year, 27 students were admitted for the Master of Public Health programme and more than 350 participants attended various short courses for continuing education in public health and health management based on applied learning approach. The next developmental steps focus on sustainability of the programmes for continuing education and research and a wider national and international partnership.
    Full-text · Article · Jan 2006 · Journal of Public Health
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    V Radosavljević · M Ilić · Slavenka Jankovic · M Djokić
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    ABSTRACT: The aim of this paper is to show influence of different foods on bladder cancer appearance, as well as possible consequent ways of prevention. Consuption of food rich in animal fat and cholesterol, fried foods, especially several times used cookin oil for frying, processed meat with additives (nitrates, nitrites, azo-colourrs) can influence bladder cancer occurrence. Regularly, continous consumption of fermented milk products, which contains come types of milky--acids bacterias, is considered as protective factor in developing bladder cancer. Reports that fruit and vegetable are protective food items are pretty consistent. Data about mineral intake and bladder cancer are obscure.
    Full-text · Article · Feb 2005 · Acta chirurgica iugoslavica
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    V Radosavljević · S Janković · J Marinković · M Dokić
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    ABSTRACT: To investigate possible relationships between diet and risk for bladder cancer in Serbia, the hospital-based case-control study was carried out. This study included 130 newly diagnosed bladder cancer patients and the same number of controls matched by sex, age (%+/-%2 years) and type of residence (rural or urban). Dietary information was obtained by using a food frequency questionnaire. Initial case-control comparisons were based on tertiles of average daily intake of control group. The odds ratios (ORs) were computed for each tertile, with the lowest tertile defined as the referent category. All variables (food items) significantly related to bladder cancer were included in multivariable logistic regression analysis. According to this analysis, risk factors for bladder cancer appeared to be consumption of liver (OR=6.60, 95%CI=1.89-23.03), eggs (OR=3.12, 95%CI=1.10-8.80), pork (OR=2.99, 95%CI=1.16-7.72), and pickled vegetable (OR=3.25, 95%CI=1.36-7.71). A protective effect was found for dietary intake of kale (OR=0.21, 95%CI=0.06-0.73), cereals (OR=0.19, 95%CI=0.06-0.62), tangerines (OR=0.21, 95%CI=0.07-0.68), cabbage (OR=0.27, 95% CI=0.11-0.68), and carrots (OR=0.15, 95%CI=0.05-0.41). The study indicated a potentially important role for dietary fat and pickled vegetables in bladder carcinogenesis. An inverse association was recorded between consumption of fruits, vegetables and cereals, and the development of bladder cancer.
    Full-text · Article · Feb 2005 · International Urology and Nephrology
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    ABSTRACT: To examine the relation of the total intake of fluids and the types of beverages to the risk of bladder cancer, we conducted a hospital based case-control study with 130 newly diagnosed bladder cancer patients and the same number of matched controls. Information of total fluid intake was derived from the reported frequency of consumption of the different types of beverages on the food frequency questionnaire. Univariate and multivariate logistic regression analyses were performed in statistical analysis. There was no statistically significant difference between the cases and the controls in total daily fluid intake. Multivariate logistic regression model showed consumption of: soda (OR=8.32; 95%CI=3.18-21.76), coffee (OR=1.46; 95%CI=1.05-2.01) and spirits (OR=1.15; 95%CI=1.04-1.28) as statistically significant risk factors, while mineral water (OR=0.52; 95%CI=0.34-0.79), skim milk (OR=0.38; 95%CI=0.16-0.91), yogurt (OR=0.34; 95%CI=0.12-0.97) and frequency of daily urination (OR=0.27; 95%CI=0.18-0.41) were statistically significant protective variables. In our study no statistically significant association was observed for total fluid intake. The findings suggest consumption of soda, coffee and spirits were indicated as a risk factors for bladder cancer, while mineral water, skim milk, yogurt and frequency of urination as protective factors for bladder cancer.
    No preview · Article · Feb 2003 · Neoplasma
  • Vladan Radosavljevic · Milena Ilic · Svetlana Jankovic

    No preview · Article · Jan 2003 · Vojnosanitetski pregled. Military-medical and pharmaceutical review
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    ABSTRACT: Purpose: This study was undertaken to assess the association of some habits as risk factors for bladder cancer development. Patients and methods: A hospital-based case-control study included 130 newly diagnosed bladder cancer patients and the same number of controls matched with respect to sex, age (±2 years) and type of residence (rural - urban) from the Clinical Center of Serbia in Beograd and from the Clinical Center in Kragujevac in central Serbia. The study took place from June 1997 to March 1999. The same doctor interviewed all the participants using a targeted and detailed questionnaire about their lifestyle. Results: All factors found to be significantly related to bladder cancer according to univariate logistic regression analysis were considered for inclusion in the multivariate logistic regression model. According to conditional logistic regression analysis, significant association with bladder cancer was found for cigarette smoking (odds ratio-OR=1.55; 95% confidence interval-CI=1.17-2.05), beer consumption (OR= 1.15; 95% CI=1.00-1.33), spirits consumption (OR=1.07; 95% CI=1.00-1.15) and coffee consumption (OR=1.06; 95% CI=1.02-1.09). Conclusion: The results of our study showed that some habits (cigarette smoking, beer, spirits and coffee consumption) were significantly associated with bladder cancer. We found no association between artificial sweeteners, wine and tea consumption and risk for bladder cancer development.
    No preview · Article · Jan 2001
  • D Bukvić · S Janković · L Dukanović · J Marinković
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    ABSTRACT: The retrospective cohort study comprised 97 Balkan endemic nephropathy (BEN) and BEN-suspected patients discovered in 1971 in the field examination in the village of Sopić, one of the regions most frequently affected by the disease. Our aim was to determine the outcome of the disease in patients and to compare the survival of BEN-suspected and BEN-manifested patients and the survival of their kidneys. The mean survival time was 16.4 years for all patients (95% CI 14.51-18.21) and 23.1 years for suspected and 13.3 years for manifested patients (log-rank = 19.46; d.f. = 1; p < 0.001). According to our results, it can be concluded that BEN is characterized by slow course and prolonged evolution and that the prognosis was consistently better for BEN-suspected than for BEN-manifested patients.
    No preview · Article · Dec 2000 · Nephron
  • D Bukvic · S Jankovic · L Dukanovic · J Marinkovic
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    ABSTRACT: The retrospective cohort study comprised 97 Balkan endemic nephropathy (BEN) and BEN-suspected patients discovered in 1971 in the field examination in the village of Sopic, one of the regions most frequently affected by the disease, Our aim was to determine the outcome of the disease in patients and to compare the survival of BEN-suspected and BEN-manifested patients and the survival of their kidneys. The mean survival time was 16.4 years for all patients (95% CI 14.51-18.21) and 23.1 years for suspected and 13.3 years for manifested patients (log-rank = 19.46; d.f. = 1; p < 0.001), According to our results, it can be concluded that BEN is characterized by slow course and prolonged evolution and that the prognosis was consistently better for BEN-suspected than for BEN-manifested patients. Copyright (C) 2000 S. Karger AG, Basel.
    No preview · Article · Dec 2000 · Nephron