[Show abstract][Hide abstract] ABSTRACT: In the present study, the plasma and erythrocyte Se concentration and the erythrocyte and leukocyte glutathione peroxidase (GSH-Px) activity in 20 patients affected by multiple sclerosis (MS) were compared with those of a group of healthy controls. The Se concentration in the food was also studied and found to be less than the minimum values suggested by the US Food and Nutrition Board. The erythrocyte Se levels were found to be similar in both MS patients and in controls, while the plasma Se values were higher in the MS patients. The Se-dependent GSH-Px activity in the erythrocytes was found to be lower in the MS patients while no difference was found in the two groups as far as the leukocytes were concerned. Our data confirm that of other authors and indicate that the modified GSH-Px activity found in erythrocytes of MS patients is independent from the Se concentration and probably due to genetic factors.
No preview · Article · Feb 1983 · European Neurology
[Show abstract][Hide abstract] ABSTRACT: 40 wistar rats were divided into two groups which had been fed one year earlier a diet in which 30% of the caloric intake consisted of rapeseed oil and peanut oil respectively. Both groups were then fed a diet of 30% peanut oil for five months and then fed a normal diet for seven months. At this time each of the two main groups was subdivided into four smaller groups, each group receiving a different diet: one of 25% rapeseed oil, one of 25% peanut oil, one of 25% butter, and one internal control group. At the end of the experiment the rats were sacrificed by decapitation. One portion of each heart was used for measuring its fatty acid content and the remaining portion was used for preparing sarcosomes on which the exigen consumption was measured polarographically. It was found that no erucic acid was present in the hearts of the rats fed rapeseed oil one year previously, and then then refed the same diet in the present experiment. The mitochondrial respiratory activity of the treated rats did not show any significant difference with respect to the found in the control groups, unlike the first experiment.
[Show abstract][Hide abstract] ABSTRACT: The role of trace elements in human nutrition has been known for a long time, but it is only in recent years that highly sophisticated techniques and equipment of analysis have made it possible to deal with this problem in concrete terms. The authors report the results of a study carried out in the People's Republic of Benin on the levels, determined by atomic absorption, of certain trace elements in the main staple foods of the local diet. Daily intakes of copper, zinc, manganese, cobalt and vanadium in Benin were calculated on the basis of a household survey and were compared with those reported for populations in some European and other countries. Relationships between serum levels of iron and copper and the levels of serum proteins, haemoglobin, haematocrit value and number of erythrocytes were also assessed in a group of newborn babies.
No preview · Article · Feb 1976 · Food and nutrition