M Basquin

Hôpital La Pitié Salpêtrière (Groupe Hospitalier "La Pitié Salpêtrière - Charles Foix"), Lutetia Parisorum, Île-de-France, France

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Publications (15)47.41 Total impact

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    ABSTRACT: Reading therapy has been shown to be effective in treating reading disabilities (RD) in dyslexic children, but little is known of its use in subjects with mild mental retardation (MR). Twenty adult volunteers, with both RD and mild MR, underwent 60 consecutive weeks in a cognitive remediation program, and were compared with 32 untreated control subjects. The experimental group showed a significant improvement in word identification, as measured by oral production (p=0.0004) or silent reading (p=0.023), and sentence comprehension (p=0.0002). Adults with MR appear to benefit from new approaches in the field of RD.
    Full-text · Article · Sep 2006 · Research in Developmental Disabilities
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    ABSTRACT: The aim of the study was to assess retrospectively patients’ and parents’ experiences and attitudes towards the use of electroconvulsive therapy (ECT) in adolescence. The experiences of subjects (n=10) who were administered ECT in adolescence for a severe mood disorder and their parents (n=18) were assessed using a semi-structured interview after a mean of 4.5 years (range, 19 months to 9 years). Their attitudes were mostly positive and ECT was considered a helpful treatment. Concerns were frequently expressed, probably because ECT was not fully understood by the patients and their families. Most complaints were of transitory memory impairment. The parents were satisfied with the consent procedure, while all but one patient did not remember the consent procedure. We concluded that, despite negative views about ECT in public opinion, adolescent recipients and their parents shared overall positive attitudes towards the use of ECT in this age range.
    Full-text · Article · Dec 2001 · Psychiatry Research
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    ABSTRACT: Cognitive functions of adolescents treated with ECT for mood disorder were evaluated at long-term follow-up. At an average of 3.5 years (SD=1.7) after the last ECT, 10 subjects treated during adolescence with bilateral ECT for severe mood disorder completed a clinical and cognitive evaluation, including the California Verbal Learning Test and Squire's Subjective Memory Questionnaire. The same assessments were given to 10 psychiatric comparison subjects matched for sex, age, and diagnosis. All cognitive test scores of the patients treated with ECT were similar to those of the comparison subjects and did not differ from norms from the community. Six of the 10 ECT-treated patients reported having had memory losses immediately after the ECT course, but only one complained of subjective memory impairment at follow-up. The results suggest that adolescents given ECT for severe mood disorder do not suffer measurable cognitive impairment at long-term follow-up.
    Full-text · Article · Apr 2000 · American Journal of Psychiatry
  • D Cohen · M Flament · O Taieb · C Thompson · M Basquin
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    ABSTRACT: The aim of this work is to discuss the ethical issues regarding the use of electroconvulsive therapy (ECT) in adolescents. Ethical implications of ECT in adolescents are analyzed in the light of general medical ethics, which include five prominent principles with respect to autonomy, nonmaleficence, beneficence, justice, and cautiousness. As adults, adolescents with acute psychotic impairment raise an inherent conflict between the respect for the patient's autonomy, on the one side, and the principle of beneficence on the other. However, this age group presents particular dilemmas: (i) As any adolescent suffering from a psychiatric illness is a highly vulnerable subject, society asks for particular attention. The consequence of potential overprotection is that the adolescent may remain untreated because of unrealistic fears regarding ECT. (ii) Some of these fears are linked to the cognitive secondary effects of ECT. Although preliminary data are reassuring, more empirical research on this population should be encouraged. (iii) Cautiousness recommends the use of ECT in limited indications catatonia, mood disorders, and intractable acute psychotic disorders. We conclude that there is no ethical reason to ban the use of ECT in adolescents. Ethical options in clinical practice must be evaluated empirically with respect to the consequences for the patient. Dogmatic views should be set aside.
    No preview · Article · Apr 2000 · European Child & Adolescent Psychiatry
  • David Cohen · Martine Flament · P F Dubos · Michel Basquin
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    ABSTRACT: This article reviews all recent (1977-1997) reports on catatonic adolescents and summarizes the 9 consecutive cases seen at the authors' institution during the past 6 years. Catatonia occurs infrequently in adolescents (0.6% of the inpatient population), but it appears to be a severe syndrome in adolescents of both sexes. Diagnoses associated with catatonia are diverse, including in this series: schizophrenia (n = 6), psychotic depression (n = 1), mania (n = 1), and schizophreniform disorder (n = 1). Two patients had a previous history of pervasive developmental disorder. In the literature, catatonia was also reported in children with organic condition (e.g., epilepsy, encephalitis). Therapeutic management depends on the specific causes, but several points need to be stressed: (1) the frequency of neuroleptic-induced adverse effects; (2) the potential efficacy of sedative drugs on motor signs; (3) the possible use of electroconvulsive therapy; and (4) the necessity to manage family reactions and fears, which are frequent causes of noncooperation. It is concluded that catatonia is an infrequent but severe condition in young people. While symptomatology, etiologies, complications, and treatment are similar to those reported in the adult literature, findings differ with regard to the female-male ratio and the relative frequencies of associated mental disorders.
    No preview · Article · Sep 1999 · Journal of the American Academy of Child & Adolescent Psychiatry

  • No preview · Article · Jul 1997 · Biological Psychiatry
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    ABSTRACT: Electroconvulsive therapy (ECT) is used in adolescent psychiatric practice, yet few studies have been conducted to assess its use for 13-19-year-olds. Efficacy, indications, side effects, technical characteristics, and outcome are uncertain. We retrospectively reviewed the medical records of 21 adolescents treated with bilateral ECT in our department from 1984 through 1995. In our series, ECT was effective in treating both maniac and depressive episodes, with a high rate of relapse at 1 year follow-up (approximately 40%). Clinical improvement was only partial and in schizophrenia and schizoaffective episodes. Seizure threshold was associated with gender, but not with the cumulative number of treatments. Adverse effects were frequent, but were usually transient with only moderate discomfort, even in patients with concomitant medical problems. We conclude that ECT is a safe and effective treatment for adolescents with severe and intractable mental illness, and it has the same indications and effects as in adults.
    No preview · Article · Apr 1997 · Convulsive therapy
  • D Cohen · C Cottias · M Basquin
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    ABSTRACT: We here describe a case of Cotard's syndrome in a 15-year-old girl who exhibited a short period of malignant catatonia, and the positive effect of electroconvulsive therapy (ECT) on her disorder. A psychopathological hypothesis is proposed.
    No preview · Article · Mar 1997 · Acta Psychiatrica Scandinavica
  • M. Herve · D. Cohen · M. Basquin
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    ABSTRACT: The most frequent evolution of non autistic infantile psychoses is a stabilization on a defective mode, with, at the symptomatic level, very limited affects, little mentalized phobic and obsessional manifestations, a more or less severe and often disharmonic deficit, making nevertheless a social insertion possible, for example in a working center for disabled people. However, there are cases whose evolution seemed favourable during the first years of care and treatment, with possibilities of acquisition and insertion in structures like Medico-Professional Institutions, but which present during adolescence a major psychotic, schizophrenic-like decompensation. From two clinical examples, we will evoke the gravity of the acute picture (mental automatism inducing severe automatic behaviours which can be initially regarded as an obsessional ritualization), and the collapse of the cognitive capacities. These decompensations call for, apart from long- term hospitalizations, a subsequent complex treating procedure linked to several factors: on the one hand, the difficulty of taking into account the current decompensation in relation to the childhood pathology, and on the other hand, the delicate orientation. These adolescents are too deficient to be able to integrate structures for adolescents such as day hospitals or medico-psychological institutions and too young to be admitted and treated in adult units. In such cases, adolescence seems to entail a severance in the evolution of infantile psychoses where a continuity between childhood and adulthood is usually found.
    No preview · Article · Jan 1997
  • D. Cohen · P.F. Dubos · M. Basquin
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    ABSTRACT: Despite the progress of pharmocotherapy, electroconvulsive therapy (ECT) is still used in a majority of countries to treat severe intractable mental disorders of the youth, yet few studies have been conducted to assess its use for individuals under 20-year-old. Efficacy, indications, side effects, technical characteristics and outcome are uncertain. A review of the 96 cases reported in the literature shows that : 1) its average frequency in adolescent psychiatric practice is similar throughout western nations and can be estimated around one ECT every year per million people ; 2) intractable mood disorders, both manic and depressive episodes, are its main indications, since ECT treated more than 90% of the 66 cases reported; ECT can also offer an interesting alternative in some schizoaffective and schizophrenic episodes, in particular catatonic ones ; 3) tolerance appears to be good, although secondary effects may occur. The most serious ones are unfrequent spontaneous seizures and more common memory loss. Although no prospective studies are available on the evolution of cognitive side effects, they seem to disappear within a few weeks.
    No preview · Article · Jan 1997 · L Encéphale
  • D. Cohen · P.F. Dubos · M. Herve · M. Basquin
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    ABSTRACT: If catatonia has become rare, it is not though exceptional and can be met during adolescence. In the light of six observations and a review of the recent literature, the authors attempt to define its main psychiatric etiologies, prognosis and therapeutic approach, particularly: 1) the recourse in certain cases to electro-convulsivotherapy in spite of the patients' early age; 2) the particular risks associated with the utilization of major tranquilizers at high posologies in this field.
    No preview · Article · Jan 1997
  • A ZIVI · M BASQUIN

    No preview · Article · Jun 1990 · Journal de Pédiatrie et de Puériculture
  • M.-L. Paillere-Martinot · A. Zivi · M. Basquin
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    ABSTRACT: Few studies report the use of ECT in adolescents. Within a period of 3 years, 9 patients aged 15 to 19 were treated by ECT in our department. Indications were acute schizophrenia, delusional depression and delusional mania, resistant to usual medication. ECT proved to be a safe treatment with good short-term outcome. Long-term outcome did not seem to be modified by treatment. These results are discussed in relation to the use of ECT in adults and adolescents reported in the literature.
    No preview · Article · Jan 1990 · L Encéphale
  • M L Paillère-Martinot · A Zivi · M Basquin
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    ABSTRACT: Few studies report the use of ECT in adolescents. Within a period of 3 years, 9 patients aged 15 to 19 were treated by ECT in our department. Indications were acute schizophrenia, delusional depression and delusional mania, resistant to usual medication. ECT proved to be a safe treatment with good short-term outcome. Long-term outcome did not seem to be modified by treatment. These results are discussed in relation to the use of ECT in adults and adolescents reported in the literature.
    No preview · Article · · L Encéphale
  • D Cohen · P F Dubos · M Basquin
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    ABSTRACT: Despite the progress of pharmocotherapy, electroconvulsive therapy (ECT) is still used in a majority of countries to treat severe intractable mental disorders of the youth, yet few studies have been conducted to assess its use for individuals under 20-year-old. Efficacy, indications, side effects, technical characteristics and outcome are uncertain. A review of the 96 cases reported in the literature shows that: 1) its average frequency in adolescent psychiatric practice is similar throughout western nations and can be estimated around one ECT every year per million people; 2) intractable mood disorders, both manic and depressive episodes, are its main indications, since ECT treated more than 90% of the 66 cases reported; ECT can also offer an interesting alternative in some schizoaffective and schizophrenic episodes, in particular catatonic ones; 3) tolerance appears to be good, although secondary effects may occur. The most serious ones are infrequent spontaneous seizures and more common memory loss. Although no prospective studies are available on the evolution of cognitive side effects, they seem to disappear within a few weeks.
    No preview · Article · · L Encéphale