[Show abstract][Hide abstract] ABSTRACT: The clinical differentiation of Parkinson's disease (PD) from multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) may be challenging, especially in their early stages. The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) measurement to distinguish among these degenerative disorders.
Twenty-five MSA, 20 PSP, and 17 PD patients and 18 healthy controls were retrospectively studied. Axial diffusion-weighted and T2-weighted images were obtained using a 3-T MR system. Regions of interest (ROIs) were precisely placed in the midbrain, pons, putamen, globus pallidus, caudate nucleus, thalamus, superior cerebellar peduncle, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus, and the regional ADC (rADC) value was calculated in each ROI.
In MSA, rADC values in the pons, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus were significantly higher than in PSP, PD, and controls. Furthermore, rADC values in the posterior putamen were significantly higher in MSA than in PSP and controls. In PSP, rADC values were significantly higher in the globus pallidus and midbrain than in MSA, PD, and controls. Furthermore, rADC values in the caudate nucleus and superior cerebellar peduncle were significantly higher in PSP than in MSA and controls. In PD, there were no significant differences in the rADC values compared to in MSA, PSP, and controls in all regions.
Evaluation of rADC values in characteristic lesions in MSA, PSP, and PD by placing ROIs using 3-T systems can provide useful additional information for differentiating these disorders.
[Show abstract][Hide abstract] ABSTRACT: We demonstrated 2 cases of uterine endometrial stromal sarcoma with emphasis on diffusion-weighted imaging. The tumors showed high signal intensity, and their tumor venous thrombi were clearly depicted on diffusion-weighted imaging. Diffusion-weighted imaging is a useful method not only for diagnosis of endometrial stromal sarcoma but also for preoperative planning.
No preview · Article · May 2010 · Journal of computer assisted tomography
[Show abstract][Hide abstract] ABSTRACT: It has been difficult to diagnose correctly white matter lesions in adult people because those changes are caused by many different factors. It is important to evaluate the distribution and signal changes of white matter lesions on each MRI sequence after obtaining patients'clinical information. Furthermore, it is necessary to evaluate their pathophysiological change, such as cytotoxic edema, vasogenic edema and tissue rarefaction, using diffusion weighted imaging. Also, white matter changes in elderly people without any symptoms are most often seen in daily MR-workup. They are clinically associated with aging and hypertension. Knowledge of the pathologic features and characteristic location of white matter changes often seen in elderly people helps understanding of MR imaging findings.